Search clinical trials for: Difelikefalin Injection

Total 9795 results

Vifor Fresenius Medical Care Renal Pharma
Tigermed Consulting Co., Ltd

Recruiting

Pharmacokinetics of Intravenous Difelikefalin in Chinese Adult Subjects on Haemodialysis

End Stage Renal Disease on Hemodialysis

China
Vifor Fresenius Medical Care Renal Pharma
Tigermed Consulting Co., Ltd

Active, not recruiting

Phase 3 Study of Difelikefalin in Haemodialysis Chinese Adult Subjects With Moderate-to-Severe Pruritus

Uremic Pruritus

China
Cara Therapeutics, Inc.

Approved for marketing

Intermediate-Size Patient Population Expanded Access Program for Intravenous Difelikefalin

Uremic Pruritus
Cara Therapeutics, Inc.

Completed

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis (KARE)

Pruritus | Atopic Dermatitis

United States, Canada
Cara Therapeutics, Inc.

Recruiting

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica

Pruritus | Notalgia Paresthetica

United States, Poland, Spain, Canada, Germany
Cara Therapeutics, Inc.

Completed

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica (KOMFORT)

Pruritus | Notalgia Paresthetica

United States, Canada
Cara Therapeutics, Inc.

Terminated

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis (KIND-1)

Pruritus | Atopic Dermatitis

United States
Cara Therapeutics, Inc.

Completed

CR845-CLIN3103: A Global Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-2)

Uremic Pruritus

United States, Canada, Czechia, Australia, Germany, Hungary, Korea, Republic of, New Zealand, Poland, Taiwan, United Kingdom
Cara Therapeutics, Inc.

Completed

CR845-100303: Study to Assess the Potential of Physical Withdrawal From Intravenous CR845 (Difelikefalin) in Hemodialysis Patients

Hemodialysis

United States
Cara Therapeutics, Inc.

Completed

CR845-CLIN3105: A Study to Evaluate the Safety and Effectiveness of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

Uremic Pruritus

United States, Czechia, Hungary, Poland
Cara Therapeutics, Inc.

Terminated

Study to Evaluate the Safety and Efficacy of Oral CR845 (Difelikefalin) in Patients With Primary Biliary Cholangitis (PBC) and Moderate-to-Severe Pruritus

Cholestatic Pruritus

United States
Cara Therapeutics, Inc.

Terminated

CR845-310302: A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States, Hungary, Australia, Germany, Korea, Republic of, Poland, Argentina, Brazil, Bulgaria, Italy, Mexico, Romania, Spain
Cara Therapeutics, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-1)

Uremic Pruritus

United States
Cara Therapeutics, Inc.

Terminated

A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States
Afyonkarahisar Health Sciences University

Completed

The Efficacy of PRP Injection in the Treatment of Rotator Cuff Syndrome (PRP)

Musculoskeletal Diseases | Shoulder Pain | Rotator Cuff Tendinopathy | Rotator Cuff Syndrome

Turkey
Vivozon, Inc.

Completed

Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Post-operative Pain Following Gastrectomy

Post-Operative Pain

Korea, Republic of
Vivozon, Inc.

Completed

Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Post-operative Pain Following Gastrectomy

Post-Operative Pain

Korea, Republic of
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Completed

Love Infection: A Dramatized Story Intervention (Telenovela/Soap Opera) for HIV Prevention (IA)

HIV Infections

United States
GlaxoSmithKline

Completed

In-patient Study With GSK716155 In Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
Rehabilitace MUDr. Hasan Mezian s.r.o.

Unknown

Effectiveness of Ultrasound Guided Corticoanesthetic Injection in Carpal Tunnel Syndrome

Carpal Tunnel Syndrome

Czechia
Cara Therapeutics, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of CR845 in Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States
University of Leipzig
Celgene Corporation

Recruiting

Efficacy of Luspatercept in ESA-naive LR-MDS Patients With or Without Ring Sideroblasts Who do Not Require Transfusions (LENNON)

Myelodysplastic Syndromes | Anemia

Germany
PersonGen BioTherapeutics (Suzhou) Co., Ltd.
Second Affiliated Hospital of Soochow University

Recruiting

UTAA17 Injection in the Treatment of Relapsed/Refractory Multiple Myeloma

Relapsed/Refractory Multiple Myeloma

China
Vivozon, Inc.

Completed

Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Postoperative Pain Following Total Hip Arthroplasty.

Post-Operative Pain

Korea, Republic of
Indiana University

Completed

Prospective Study of Celiac Block Injection: 1 vs. 2

Pancreatic Cancer | Chronic Pancreatitis

United States
Labrha
Statitec

Completed

Safety of Use of Pandora for Patients Suffering From Gonarthrosis (PANDORA1)

Knee Osteoarthritis

France
Istituto Ortopedico Rizzoli

Recruiting

Homologous PRP vs Placebo in Knee Osteoarthritis in Over 65 Years Old Patients

Knee Osteoarthritis

Italy
Western Galilee Hospital-Nahariya

Recruiting

Comparing Methods for Balloon Catheter Inserting: View Guided (Speculum) Versus Manual Guided at Cervical Examination

Cervical Ripening

Israel
Rothman Institute Orthopaedics

Unknown

Study Comparing One Versus Two Cortisone Injections for Trigger Finger

Trigger Finger | Stenosing Tenosynovitis

United States
Yangzhou University

Not yet recruiting

Application of Different Modes of Esketamine Administration in Pediatric Day Circumcision

Pain
Indiana University School of Medicine

Completed

Does Inspection During Insertion Improve Adenoma Yields During Colonoscopy?

Colorectal Cancer | Colorectal Polyps

United States
Theravectys S.A.

Not yet recruiting

A Study to Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer

HPV-Related Cervical Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma

United States
Makassed General Hospital

Recruiting

Effectiveness of Single Paravertebral Blockade Injection for Herniorrhaphy in Children

Reduce Pain After Herniorrhaphy

Lebanon
Cara Therapeutics, Inc.

Completed

Study to Investigate the Effects of Single Intravenous Doses of Difelikefalin (CR845) on the QTc Interval in Healthy Subjects

Healthy

United States
Geisinger Clinic

Terminated

Effect of Subcutaneous Semaglutide on Kidney Transplant Candidacy (RAISE-KT)

Obesity | Diabetic Kidney Disease | Type 2 Diabetes Mellitus in Obese | CKD | Severe Obesity

United States
Roxall Medizin

Completed

Efficacy and Safety of Specific Immunotherapy With CLUSTOID Grass Pollen

Allergic Rhinitis

Germany
Sindolor

Suspended

Safety and Efficacy of EZ-Ject Injector a Pain-Free Subcutaneous Automatic Injection in Healthy Volunteers

Healthy

Israel
Ciusss de L'Est de l'Île de Montréal

Recruiting

Thoracic Paravertebral Block Anesthesia for Breast Cancer Surgery (TPVB)

Breast Cancer | Breast Neoplasms | Breast Neoplasm Female | Cancer, Breast

Canada
Bispebjerg Hospital

Active, not recruiting

Resistance Training and Injection Treatment for Achilles Enthesopathy

Achilles Entesopathy

Denmark
London North West Healthcare NHS Trust

Completed

Does Inspection of Colonic Mucosa During Insertion Improve Adenoma Detection? (INWARD)

Adenoma Colon | Serrated Adenoma

United Kingdom
Cellular Biomedicine Group Ltd.

Not yet recruiting

Allogenic Adipose-Derived Mesenchymal Progenitor Cells for the Treatment of Knee Osteoarthritis

Knee Osteoarthritis

China
Kyunghee University Medical Center

Completed

Efficacy of Acupuncture and Bee Venom Acupuncture on Patients With Idiopathic Parkinson's Disease

Idiopathic Parkinson's Disease

Korea, Republic of
The Filatov Institute of Eye Diseases and Tissue...
Odessa National Medical University; Mykolaiv Region Ophthalmogical Hospital; Central... and other collaborators

Recruiting

Brolucizumab for CNV Associated With Pathologic Myopia (COASTUAbaCNV)

Pathologic Myopia

Ukraine
Peking University Third Hospital

Not yet recruiting

Needle-Free Subcutaneous Injector and Conventional Intramuscular Injection of Mecobalamin in Diabetes Peripheral Neuropathy

Diabetic Peripheral Neuropathy
Brainstorm-Cell Therapeutics
Hadassah Medical Organization

Completed

Autologous Mesenchymal Bone Marrow Stromal Cells Secreting Neurotrophic Factors (MSC-NTF), in Patients With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Israel
National Taiwan University Hospital

Recruiting

Comparison of Effectiveness Between PL and PRP on Knee Osteoarthritis: a Prospective,Randomized,Placebo-controlled Trial

Osteoarthritis (OA) of the Knee

Taiwan
Jiangsu HengRui Medicine Co., Ltd.

Completed

To Compare the Pharmacokinetics and Pharmacodynamics of HR20014, INS068 and INS062 After Single Subcutaneous Injection in Healthy Subjects

Diabetes

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

Pharmacokinetics of HR17031 Injection in Healthy Subjects

Type 2 Diabetes Mellitus

China
Universitaire Ziekenhuizen KU Leuven

Withdrawn

Ictal SPECT With Intra-arterial Injection

Epilepsy

Belgium
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Enrolling by invitation

A Trial of SHR-2002 Injection or Combined With Other Anti-cancer Medication in Advanced Malignant Tumors of Patients

Advanced Malignant Tumors

China

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