Search clinical trials for: Dihydroartemisinin/Piperaquine

Total 206 results

London School of Hygiene and Tropical Medicine
Medical Research Council Unit, The Gambia

Terminated

Evaluation of the Safety of Primaquine in Combination With Dihydroartemisinin-piperaquine in G6PD Deficient Males in The Gambia (SAFEPRIM-II)

Malaria

Gambia
University of Oxford
Mahidol Oxford Tropical Medicine Research Unit

Completed

P.Vivax Treatment Trial (Lao Pv)

Plasmodium Vivax

Lao People's Democratic Republic
Indonesia University

Completed

Dihydroartemisinin-piperaquine and Primaquine for Uncomplicated Plasmodium Falciparum Cases (DHP+PQ)

Malaria

Indonesia
Liverpool School of Tropical Medicine
The Research Council of Norway; Makerere University; Kenya Medical Research Institute

Completed

Post-discharge Malaria Chemoprevention(PMC) Study (PMC)

Malaria | Severe Anemia

Uganda, Kenya
Richard Mwaiswelo
National Institute for Medical Research, Tanzania; Muhimbili University of... and other collaborators

Completed

Dihydroartemisinin-piperaquine for Seasonal Malaria Chemoprophylaxis in Tanzania (SMC-DP)

Malaria | Chemoprophylaxis | Underfive Children

Tanzania
Menzies School of Health Research
World Health Organization; Eijkman Institute for Molecular Biology

Completed

Efficacy and Safety of Dihydroartemisinin-piperaquine (DHP) for the Treatment of Uncomplicated Malaria

Plasmodium Falciparum Infection | Plasmodium Vivax Infection

Indonesia
University of California, San Francisco
Mahidol University; Holley-Cotec Pharmaceuticals Co., LTD.

Completed

Pharmacokinetics of Dihydroartemisinin-Piperaquine in the Treatment of Uncomplicated Malaria in Children in Burkina Faso

Uncomplicated Malaria
National Institute for Medical Research, Tanzania
National Malaria Control Program, Tanzania

Active, not recruiting

Evaluation of the Implementation and Effectiveness of Intermittent Preventive Treatment for Malaria Using Dihydroartemisinin-piperaquine on Reducing Malaria Burden in School Aged Children in Tanzania (IPTsc)

Malaria

Tanzania
Centro de Investigação em Saúde de Manhiça
Barcelona Institute for Global Health

Completed

Mass Drug Administrations of DHA-PQP to Accelerate Towards Malaria Elimination in Magude District, Southern Mozambique (MDAM)

Malaria
London School of Hygiene and Tropical Medicine
University of Sheffield; Institute of Tropical Medicine, Belgium

Completed

RHOST-cRCT, Reactive Household-based Self-administered Treatment Against Residual Malaria Transmission (RHOST)

Malaria

Gambia
Simon Kariuki
Centers for Disease Control and Prevention

Completed

Evaluation of Community-based Mass Screening and Treatment for Malaria in Western Kenya (MSaT)

Malaria,Falciparum
Lihir Medical Centre
Barcelona Institute for Global Health; Papua New Guinea Institute of Medical... and other collaborators

Completed

Cardiac Safety of Repeated Doses of Dihydroartemisinin-Piperaquine for the Use in Mass Treatment Campaigns (ECG-Lihir)

Malaria

Papua New Guinea
INDEPTH Network
Centro de Investigação em Saúde de Manhiça; Ministry of Health, Burkina Faso; Ifakara Health Research and Development Centre and other collaborators

Unknown

Introduction of Eurartesim® in Burkina Faso, Mozambique, Ghana and Tanzania

Malaria

Burkina Faso, Ghana, Mozambique, Tanzania
London School of Hygiene and Tropical Medicine
University of California, San Francisco; Infectious Diseases Research Collaboration... and other collaborators

Completed

School-Based Treatment With ACT to Reduce Transmission (START-IPT)

Malaria

Uganda
Gadjah Mada University
Menzies School of Health Research; Eijkman Institute for Molecular Biology; Timika...

Completed

Malaria in Early Life Study

Plasmodium Falciparum Malaria | Plasmodium Vivax Malaria

Indonesia
Makerere University

Recruiting

Household-level Impact of IPT of Malaria in Schoolchildren

Malaria

Uganda
Armed Forces Research Institute of Medical Sciences...
United States Army Medical Materiel Development Activity

Completed

Malaria Active Epidemiology and Treatment Study

Malaria

Cambodia
Alfasigma S.p.A.

Terminated

Eurartesim® in Patients With Imported Uncomplicated Plasmodium Vivax Malaria

Malaria, Vivax

Switzerland, France, Germany, Israel, Italy, Netherlands, Spain
University of Oxford
Mahidol Oxford Tropical Medicine Research Unit; Department of Medical Research...

Withdrawn

Arterolane-PQP Versus DHA-PQP in Uncomplicated Falciparum Malaria in Eastern Myanmar

Uncomplicated Falciparum Malaria | Artemisinin-resistant
Grant Dorsey, M.D, Ph.D.
National Institute of Allergy and Infectious Diseases (NIAID); Karolinska Institutet and other collaborators

Active, not recruiting

Modifying Immunity in Children With DihydROartemisinin-Piperaquine (MIC-DroP) (MIC-DroP)

Malaria

Uganda
London School of Hygiene and Tropical Medicine
Bandim Health Project; Medical Research Council Unit, The Gambia; Ministerio... and other collaborators

Recruiting

Adjunctive Ivermectin Mass Drug Administration for Malaria Control (MATAMAL)

Lymphatic Filariasis | Scabies | Malaria,Falciparum | Strongyloidiasis | Neglected Tropical Diseases | Hook Worm | Soil Transmitted Helminths

Guinea-Bissau
University of California, San Francisco
Centers for Disease Control and Prevention; Population Services International; L'université de Thiès and other collaborators

Completed

Mass Drug Administration of Dihydroartemisinin-piperaquine + Single Low-dose Primaquine to Accelerate Toward Elimination Activities

Malaria | Malaria,Falciparum

Senegal
London School of Hygiene and Tropical Medicine
Radboud University Medical Center; International Centre of Insect Physiology...

Completed

Dihydroartemisinin-piperaquine With Low Dose Primaquine to Reduce Malaria Transmission (DAPPI)

Malaria | Plasmodium Falciparum | Asymptomatic Malaria

Kenya
Grant Dorsey, M.D, Ph.D.
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Reducing the Burden of Malaria in HIV-uninfected Pregnant Women and Infants (PROMOTE-BC1)

Malaria

Uganda
University of California, San Francisco
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Dihydroartemisinin-Piperaquine in the Context of Antiretroviral Therapy (DPART)

HIV Infection | Drug-Drug Interaction

Uganda
Barcelona Institute for Global Health
Medical University of Vienna; Centro de Investigação em Saúde de Manhiça; Centre... and other collaborators

Completed

Improving Maternal heAlth by Reducing Malaria in African HIV Women (MAMAH)

HIV/AIDS | Pregnancy Related | Malaria

Gabon, Mozambique
Liverpool School of Tropical Medicine
Indonesia-MoH; Gadjah Mada University; Yayasan Pengembangan Kesehatan dan Masyarakat...

Completed

Intermittent Preventive Treatment With Dihydroartemisinin-piperaquine in Papua, Indonesia (STOPMiP-2)

Malaria in Pregnancy

Indonesia
Liverpool School of Tropical Medicine
Centers for Disease Control and Prevention; Kenya Medical Research Institute

Completed

Efficacy and Safety of High-dose Ivermectin for Reducing Malaria Transmission: A Dose Finding Study (IVERMAL)

Malaria

Kenya
Malaria Consortium
Centers for Disease Control and Prevention; World Health Organization; National... and other collaborators

Completed

Safety and Tolerability of Low Dose Primaquine

Malaria, Falciparum | G6PD Deficiency

Cambodia
University of Oxford

Completed

Pharmacokinetic and Pharmacodynamic Study of Mefloquine and Dihydroartemisinin-Piperaquine in Healthy Subjects

Healthy

Thailand
Kamuzu University of Health Sciences
London School of Hygiene and Tropical Medicine; University of Bergen; The Research... and other collaborators

Unknown

Delivery of Malaria Chemoprevention in the Post-discharge Management of Children With Severe Anaemia in Malawi (PMC)

Malaria | Severe Anemia

Malawi
University of Oxford

Completed

Comparison of the ECG Effects Related to Pharmacokinetic Profile of Chloroquine and Piperaquine

Healthy

Thailand
London School of Hygiene and Tropical Medicine

Completed

Single Low Dose Tafenoquine to Reduce P. Falciparum Transmission in Mali (NECTAR2) (NECTAR2)

Malaria, Falciparum

Mali
London School of Hygiene and Tropical Medicine
Radboud University Medical Center; Imperial College London; Institute of Tropical... and other collaborators

Completed

Mass Drug Administration of Ivermectin and Dihydroartemisinin-piperaquine as an Additional Intervention for Malaria Elimination (MASSIV)

Malaria

Gambia
National Institute of Allergy and Infectious Diseases...

Completed

Efficacy, Safety, and Tolerability of Dihydroartemisinin-piperaquine + Mefloquine Compared to Dihydroartemisinin-piperaquine or Artesunate-mefloquine in Patients With Uncomplicated Falciparum Malaria in Cambodia

Acute Falciparum Malaria

Cambodia
Oxford University Clinical Research Unit, Vietnam
Wellcome Trust; Agency for Science, Technology and Research; Hospital for Tropical... and other collaborators

Completed

Antimalarial Drug Susceptibility and Molecular Characterization of Plasmodium Vivax Isolates in Vietnam

Plasmodium Vivax Malaria

Vietnam
Jhpiego
United States Agency for International Development (USAID); Centers for Disease... and other collaborators

Completed

Malaria Therapeutic Efficacy Study (TES) Kenya (Kenya-TES)

Uncomplicated Malaria

Kenya
Liverpool School of Tropical Medicine
University of Copenhagen; University of Toronto; Centers for Disease Control... and other collaborators

Completed

Improving PRegnancy Outcomes With PReVEntive Therapy in Africa-2 (IMPROVE-2) (IMPROVE-2)

Pregnancy; HIV; Malaria

Kenya
University of California, San Francisco
University of Texas; Ministry of Health, Swaziland; Clinton Health Access Initiative...

Completed

Evaluation of Reactive Focal Mass Drug Administration for Malaria Elimination in Swaziland (fMDA)

Malaria

Swaziland
Liverpool School of Tropical Medicine
University of Bergen; Indiana University; Makerere University; University of Malawi and other collaborators

Completed

Dihydroartemisinin-Piperaquine or Sulphadoxine-Pyrimethamine for the Chemoprevention of Malaria in Sickle Cell Anaemia (CHEMCHA)

Malaria | Sickle Cell Anemia in Children

Uganda, Malawi
National Institute for Medical Research, Tanzania
World Health Organization; Muhimbili University of Health and Allied Sciences

Completed

Efficacy and Safety of ASAQ and PD for the Treatment of Uncomplicated Falciparum Malaria in Mainland Tanzania (GF-TES-2017)

Uncomplicated Falciparum Malaria

Tanzania
Indonesia University

Completed

Impact of Dihydroartemisinin-piperaquine Plus Primaquine on Malaria Transmission in Lampung Province, Sumatra

Malaria

Indonesia
Liverpool School of Tropical Medicine
London School of Hygiene and Tropical Medicine; University of Bergen; Kamuzu... and other collaborators

Completed

Acceptability and Feasibility in the Context of the IMPROVE Trial in Kenya

Malaria in Pregnancy | Adherence, Treatment

Kenya
sigma-tau i.f.r. S.p.A.

Completed

A Pharmacokinetic/Pharmacodynamic Study of Eurartesim Dispersible Formulation in Infants With P.Falciparum Malaria

Malaria,Falciparum

Burkina Faso, Congo, The Democratic Republic of the, Gambia, Mozambique, Tanzania
Indonesia University
Walter and Eliza Hall Institute of Medical Research

Completed

Surveillance and Treatment With Dihydroartemisinin-piperaquine Plus Primaquine

Malaria

Indonesia
Makerere University
Bill and Melinda Gates Foundation

Completed

School Based Malaria Control in Ugandan Schoolchildren (SBMC)

Malaria

Uganda
Oxford University Clinical Research Unit, Vietnam
World Health Organization

Completed

Study of Malaria Treatment at Phuoc Long Hospital, Binh Phuoc Province, Vietnam

Malaria

Vietnam
National Institute for Medical Research, Tanzania
World Health Organization; Ministry of Health and Social Welfare, Tanzania

Completed

In-vivo Efficacy and Safety of Artemether/Lumefantrine Vs Dihydroartemisinin-piperaquine for Treatment of Uncomplicated Malaria and Assessment of Parasite Genetic Factors Associated With Parasite Clearance or Treatment Failure (WB-Malaria)

Malaria

Tanzania
University of Maryland, Baltimore
Kamuzu University of Health Sciences; Doris Duke Charitable Foundation

Completed

Comparing Chemoprevention Approaches for School-based Malaria Control

Malaria,Falciparum | Anemia in Children

Malawi
Ifakara Health Institute

Completed

Safety, Tolerability, Pharmacokinetics and Efficacy of ARCO

Malaria, Falciparum | Plasmodium Falciparum

Tanzania

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