Search clinical trials for: Direct acting Anti-Viral Therapy using Epclusa or Zepatier

Total 275 results

Virginia Commonwealth University

Completed

Hepatitis C Virus Donor Positive Kidney Transplantation for Hepatitis C Virus Negative Recipients

Hepatitis C | Kidney Transplant

United States
Massachusetts General Hospital

Terminated

Pan-genotypic Direct Acting Antiviral Therapy in Donor HCV-positive to Recipient HCV-negative Lung Transplant

Hepatitis C | Respiratory Failure

United States
Soroka University Medical Center
Loyola University, Harel Dahari, PhD, mathematical modeling support

Completed

Response Guided Treatment With Direct Acting Anti-Viral Medications for Chronic HCV Infection

Hepatitis C

Israel
University of Zurich

Completed

Swiss HCVree Trial (HCVree)

Hepatitis C | HIV

Switzerland
Raymond T. Chung, MD
Merck Sharp & Dohme LLC

Withdrawn

Preemptive Zepatier Treatment in Donor HCV Positive to Recipient HCV Negative Cardiac Transplant

Hepatitis C | Cardiac Transplant Disorder

United States
Hospices Civils de Lyon

Completed

Anti-E1E2 (D32.10 Epitope-binding) Antibodies Status Prior Therapy Favors Direct-acting Antiviral Treatment Efficacy

Chronic Hepatitis c

France
National Taiwan University Hospital

Completed

eGFR Evolution in HCV Patients Receiving SOF-based or SOF-free DAAs

Hepatitis C | Viral Hepatitis C | Renal Disease

Taiwan
ANRS, Emerging Infectious Diseases

Not yet recruiting

Study Evaluating the Safety, in Terms of HBV Virological Control at 96 Weeks, of 2 Antiviral Treatment Relief Strategies, in Patients Co-infected With the HIV-1 and HBV Viruses (BI-LIGHT)

HIV Infections | HBV Coinfection
University of Latvia
National Institute of Public Health, Slovenia; Iuliu Hatieganu University of... and other collaborators

Recruiting

H. Pylori Screen-and-treat Study in a Population of Young Adults

Gastric Cancer | H Pylori Infection | H Pylori Eradication | H-pylori

Poland, Croatia, Ireland, Latvia, Romania, Slovenia
Ain Shams University

Completed

Early Treatment of Recurrent HCV- Infection Post Liver Transplantation in the Era of DAAs

Liver Transplantation
National Center for Global Health and Medicine,...

Completed

Safety Study of Maraviroc's Effect on Human Osteoclasts (MVC-Bone)

HIV Infections | AIDS

Japan
YingHsuanTai

Withdrawn

Multi-Strategy Intervention for Anesthesia Care of Obese Patients A Factorial Randomized Controlled Trial

Obesity | Bariatric Surgery Candidate | Tracheal Intubation Morbidity | Nausea and Vomiting, Postoperative | Gastric Reflux | Hyperglycemia Drug Induced

Taiwan
ANRS, Emerging Infectious Diseases

Completed

Study to Assess Efficacy and Safety of Grazoprevir/Elbasvir Associated With Sofosbuvir and Ribavirin in HCV Genotype 1 or 4-infected Patients Who Failed Direct Acting Antivirals (DAA) Bitherapy With Sofosbuvir

Hepatitis C
Ain Shams University

Not yet recruiting

Effect of Dapagliflozin in Non-Diabetic Patients With Nephrotic Syndrome.

Nephrotic Syndrome
CytoDyn, Inc.

No longer available

A Compassionate Use Study of Leronlimab in Breast Cancer

Metastatic Triple-Negative Breast Carcinoma
EBG MedAustron GmbH

Recruiting

Radiotherapy for Locally Advanced Pancreatic Carcinomas (Phase II Trial) (LAPC)

Pancreas Cancer

Austria
Hoffmann-La Roche

Completed

INNOVE Study: A Study of 3 Months Induction With Fuzeon (Enfuvirtide) + Optimized Background (OB) Versus OB Alone in HIV-1 Infected Patients With Virological Failure.

HIV Infections

France
Hoffmann-La Roche

Withdrawn

ESP Study: A Study to Assess the Effect of Adding Fuzeon (Enfuvirtide) to an Antiretroviral Regimen in Fuzeon-Naive Patients With Sustained HIV Viral Suppression.

HIV Infections

Australia
University Hospital, Tours
University Hospital, Rouen; Central Hospital, Nancy, France; Poitiers University... and other collaborators

Completed

Trial to Evaluate the Interest of a Reductive Anti Retroviral Strategy Using Dual Therapy Inspite of Triple Therapy (TRULIGHT)

HIV

France
ViiV Healthcare
Pfizer

Completed

Combivir And Maraviroc In Antiretroviral Naive Subjects In Russia

HIV

Russian Federation
Catholic University of the Sacred Heart

Terminated

Switch to Darunavir/r + Maraviroc Quaque Die in Patients With R5 Tropism by Viral DNA Genotyping (GUSTA) (GUSTA)

HIV Infection

Italy
Rennes University Hospital

Completed

Trial Involving Subjects Over 70 Years of Age With Non Small-cell Lung Cancer of Stage IV and Comparing a "Classical" Strategy of Treatment Allocation, With an"Optimized" Strategy Allocating the Same Treatments (ESOGIA)

Non Small-cell Lung Cancer

France
Abramson Cancer Center of the University of Pennsylvania
National Cancer Institute (NCI)

Terminated

Nelfinavir Mesylate, Radiation Therapy, and Temozolomide in Treating Patients With Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Fundación de Investigación Biomédica - Hospital...

Recruiting

Identification of Predictive Biomarkers for Response to Biologic Therapies and Tofacitinib in Inflammatory Bowel Disease (BioIBD)

Inflammatory Bowel Diseases | Crohn Disease | Ulcerative Colitis

Spain
ViiV Healthcare
Pfizer

Completed

Trial of Maraviroc (UK-427,857) in Combination With Optimized Background Therapy Versus Optimized Background Therapy Alone for the Treatment of HIV-1 Infected Subjects (MOTIVATE 2)

HIV Infections

Netherlands, United States, Italy, Spain, United Kingdom, France, Germany, Australia, Switzerland, Belgium, Canada, Poland, Sweden
Hospital Universitario Infanta Leonor
Hospital Clinic of Barcelona; ViiV Healthcare

Terminated

Study to Evaluate the Efficacy and Safety of Maraviroc in SARS-CoV-2 Infection (COVID-19). (MARACOVID)

COVID-19

Spain
ANRS, Emerging Infectious Diseases
Janssen Pharmaceuticals

Completed

Evaluation of a Maintenance Strategy With Protease Inhibitors With or Without Lamivudine in Virologically Suppressed HIV Patients on Second Line Antiretroviral Treatment in Africa (MOBIDIP)

HIV Infection

Cameroon, Burkina Faso, Senegal
Medical Research Council
NHS Health Technology Assessment Programme

Unknown

Protease Inhibitor Monotherapy Versus Ongoing Triple-therapy in the Long Term Management of HIV Infection (PIVOT) (PIVOT)

Acquired Immunodeficiency Syndrome | HIV Infection
ANRS, Emerging Infectious Diseases

Completed

First-Line Treatment for HIV-2 (FIT-2)

HIV-2 Infection

Côte D'Ivoire, Burkina Faso, Senegal, Togo
Mahidol University

Recruiting

Effects of Transcranial Electrical Stimulation in Stroke Individuals

Ischemic Stroke | Hemorrhagic Stroke | Chronic Stroke | Subacute Stroke

Thailand
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

UNCPM 22314 - Pregnancy, Infant and Maternal Health Outcomes Study (PrIMO)

Pregnancy Related | HIV Prevention | Pre-exposure Prophylaxis

Malawi
ViiV Healthcare
Pfizer

Completed

Trial of Maraviroc (UK-427,857) in Combination With Optimized Background Therapy Versus Optimized Background Therapy Alone for the Treatment of Antiretroviral-Experienced NonCCR5-Tropic HIV-1 Infected Subjects

HIV Infections

Canada, United States, United Kingdom, Netherlands, Australia, Germany, Spain, Belgium, Switzerland
ViiV Healthcare
Pfizer

Completed

Trial of Maraviroc (UK-427,857) in Combination With Optimized Background Therapy Versus Optimized Background Therapy Alone for the Treatment of HIV-1 Infected Subjects (MOTIVATE 1)

HIV Infections

United States, Canada
University of Maryland, Baltimore

Completed

Switch to Maraviroc + Integrase Inhibitor

HIV

United States
BioXcellerator
Clinical Somer

Recruiting

Safety and Efficacy of Intravenous Wharton's Jelly Derived Mesenchymal Stem Cells in Acute Respiratory Distress Syndrome Due to COVID 19

Acute Respiratory Distress Syndrome

Colombia
Shandong University

Unknown

The Associations Between the Gastric Mucosal Pathology and the Eradication Rate of H.Pylori :A Multicenter Study

Helicobacter Pylori

China
Abbott Medical Devices

Terminated

Safety Study on Stopping Anticoagulation Medication in Patients With a History of Atrial Fibrillation (TACTIC AF)

Atrial Fibrillation

United States
Nanjing First Hospital, Nanjing Medical University

Not yet recruiting

Efficacy and Safety of Tegoprazan Dual Therapy and Furazolidone-based Bismuth Quadruple Therapy for Helicobacter Pylori Eradication: A Prospective, Multicenter, Open-label, Randomized Controlled Clinical Study

Helicobacter Pylori Infection | Tegoprazan | Furazolidone
University of Florida
Patient-Centered Outcomes Research Institute; Merck Sharp & Dohme LLC; AbbVie

Completed

Study of Oral Treatments for Hepatitis C (PRIORITIZE)

Chronic Hepatitis C

United States
Tata Memorial Hospital

Recruiting

Radiosensitizing Effect of Nelfinavir in Locally Advanced Carcinoma of Cervix (NELCER)

Carcinoma Cervix,Stage III

India
Radboud University Medical Center

Completed

Pharmacokinetic and Safety Study of Raltegravir and Atazanavir in a Once Daily Dose Regimen in HIV-1 Infected Patients (PRADA)

HIV Infections | HIV Infection

Germany, Netherlands
University of Utah

Terminated

Chemoradiation +Gemcitabine +Continuous 5-FU (Fluorouracil) Followed by High Dose Brachytherapy/Stereotactic Radiation Boost in Locally Advanced Intra/Extrahepatic Cholangiocarcinoma

Cancer

United States
Bristol-Myers Squibb

Completed

Taste Properties of Atazanavir and Cobicistat

HIV in Adults

United States
University of Athens
KAT Hospital of Athens

Completed

Teicoplanin Prophylaxis for Total Hip or Knee Arthroplasty

Total Hip and Knee Arthroplasties

Greece
University of California, Los Angeles

Terminated

Maraviroc to Augment Rehabilitation Outcomes After Stroke (MAROS)

Stroke

United States
University of Birmingham
University of Oxford; University Hospital Birmingham NHS Foundation Trust; London... and other collaborators

Recruiting

Preventing Stroke, Premature Death and Cognitive Decline in a Broader Community of Patients With Atrial Fibrillation (DaRe2THINK)

Atrial Fibrillation

United Kingdom
Fundacion SEIMC-GESIDA
Janssen, LP

Completed

Study to Evaluate Darunavir/Ritonavir + Lamivudine Versus Continuing With Darunavir/Ritonavir + Tenofovir/Emtricitabine or Abacavir/Lamivudine in HIV Infected Subject (DUAL)

HIV Infection

Spain
Hospital General de México Dr. Eduardo Liceaga
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran; CCINSHAE... and other collaborators

Terminated

Safety and Efficacy of Maraviroc and/or Favipiravir With Standard Therapy in Severe COVID-19 Adults (COMVIVIR)

COVID-19

Mexico
International Maternal Pediatric Adolescent AIDS...
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy...

Terminated

Evaluation of 3TC or FTC Mono-therapy Compared to Continuing HAART as a Bridging Strategy (P1094)

HIV Disease

United States, Puerto Rico, Argentina, Brazil, Thailand
Sociedad Andaluza de Enfermedades Infecciosas

Completed

Clinical Trial, Open-label, Randomised, in Order to Compare the Quality of Life for Those VIH+ Patients That Start With Monotherapy on LPV/r Tablets Vs. Triple Therapy With a Boosted Protease Inhibitor (QoLKAMON)

HIV Infection

Spain

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