Search clinical trials for: Dopamine D2 Receptor Antagonists

Total 10561 results

Massachusetts General Hospital

Withdrawn

Open-Label Study of Latuda for the Treatment of Mania in Children and Adolescents 6-17 Years Old

Bipolar Disorder | Mania | Bipolar I | Bipolar II | Bipolar Spectrum Disorder

United States
Sunovion

Completed

Lurasidone Pediatric Autism Study

Autism

United States
UCB Pharma

Completed

A Randomized, Open-label, Two-way Crossover Trial to Determine the Pharmacokinetics of Metoclopramide When Administered as the Orally Disintegrating Tablet Compared to Reglan® Tablets in Subjects With Diabetic Gastroparesis

Diabetic Gastroparesis

United States
Luye Pharma Group Ltd.

Completed

Relative Bioavailability of LY03010 Compared to Listed Drug

Mental Disorders | Psychotic Disorders | Mood Disorders | Schizophrenia | Molecular Mechanisms of Pharmacological Action | Tranquilizing Agents | Physiological Effects of Drugs | Psychotropic Drugs | Antipsychotic Agents | Central Nervous System Depressants | Neurotransmitter Agents | Schizophrenia Spectrum

United States
Ortho-McNeil Janssen Scientific Affairs, LLC

Terminated

28-30 Month Study Comparing Paliperidone Palmitate With Oral Risperidone for Treating Adults Diagnosed With Schizophrenia Within the Past 5 Years

Schizophrenia

United States, China, Colombia, Bulgaria, India, Malaysia, Russian Federation, Ukraine, Canada, Korea, Republic of, Brazil, Czech Republic
Johnson & Johnson Pharmaceutical Research & Development...

Completed

Trial Evaluating the Efficacy and Safety of 2 Fixed Doses of Paliperidone Extended-Release (ER) Tablets in the Treatment of Adult Patients With Schizophrenia

Schizophrenia
University of California, Irvine
Janssen, LP

Unknown

Contrasting the Brain Effects of Risperidone and Invega With Functional Magnetic Resonance Imaging (fMRI) and Positron Emission Tomography (PET) Scanning

Schizophrenia

United States
Barzilai Medical Center

Unknown

Efficacy of Metoclopramide in Poor Ovarian Response IVF Patients

Poor Responders in IVF
Takeda
Theravance Biopharma

Completed

A Randomized, Double-Blind Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of a Single Dose of Intravenous TD-8954 Compared With Metoclopramide in Critically Ill Patients With Enteral Feeding Intolerance

Enteral Feeding Intolerance

Australia
University Hospital, Bordeaux

Completed

Subcutaneous Route and Pharmacology of Metoclopramide (SOPHA-Méto)

Nausea | Vomiting

France
NeuroRx, Inc.
Target Health Inc.

Active, not recruiting

NRX-101 for Maintenance of Remission From Severe Bipolar Depression in Patients With Suicidal Ideation (SBD-ASIB)

Suicidal Ideation | Bipolar Depression

United States
Sumitomo Pharma Co., Ltd.

Completed

A Phase III Study of SM-13496 in Patients With Bipolar I Depression.

Bipolar Depression

Lithuania, Malaysia, Russian Federation, Slovakia, Ukraine, Japan, Philippines, Taiwan
Sunovion

Completed

A Study Evaluating Lurasidone for The Treatment of Schizophrenia or Schizoaffective Disorder in Subjects Switched From Other Antipsychotic Agents (SWITCHCore)

Schizophrenia | Schizoaffective Disorder

United States
Sunovion

Completed

Rifampin Drug-Drug Interaction Study With Lurasidone HCl

Male, Healthy Normal Subjects

United States
Sunovion

Completed

Digoxin Drug-Drug Interaction With Lurasidone HCl

Schizophrenia

United States
Simon Fisher
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Restoration of Hypoglycemia Awareness With Metoclopramide

Hypoglycemia Unawareness

United States
The Hospital for Sick Children
The Physicians' Services Incorporated Foundation

Terminated

Metoclopramide Pilot Trial

Gastroschisis

Canada
Ain Shams University

Unknown

Itopride in Feeding Intolerance of Critically-ill Patients Receiving Enteral Nutrition

Critically-ill Patients

Egypt
Children's Hospital of Philadelphia

Completed

Treatment of Acute Migraine Headache in Children

Migrainous Headache

United States
Mercy Health System

Recruiting

Metoclopramide in Upper Gastrointestinal Bleed

Upper GI Bleeding | Bleeds Gastric | Bleed Ulcer | Hemorrhage Gastric | Hemorrhage; Ulcer

United States
King Chulalongkorn Memorial Hospital

Completed

Metoclopramide for Acute Upper GI Bleeding

Acute Upper Gastrointestinal Bleeding | Effect of Drug

Thailand
Winthrop University Hospital

Terminated

Study to Evaluate the Efficacy of Oral Dissolving Metoclopramide Before Video Capsule Endoscopy

Gastric Transit Time

United States
Clinical Evaluation Research Unit at Kingston General...
Nestlé Health Science

Terminated

PEP uP Protocol in Surgical Patients

Critically Ill

United States
Nathalie Charpak
Hospital Universitario San Ignacio; Pontificia Universidad Javeriana

Completed

Methoclopramide for Gastroesophageal Reflux in Premature Infants

Gastroesophageal Reflux

Colombia
Assiut University
Esam Hamed; Wafaa Hamza

Unknown

Ultrasound Assessment of Metoclopramide Effect on Gastric Volume in Cesarean Section

Aspiration Pneumonia

Egypt
Millennium Pharmaceuticals, Inc.

Terminated

TAK-954 in Critically Ill Participants With Enteral Feeding Intolerance (EFI)

Critical Illness | Enteral Nutrition | Enteral Feeding Intolerance

United States, Canada, Australia, United Kingdom
National University Hospital, Singapore
The University of Western Australia

Completed

Maxolon to Improve Breastmilk Supply in Diabetic Women: a Randomised Controlled Trial (Maxalon)

Breastfeeding

Singapore
University of California, Los Angeles
National Institute of Mental Health (NIMH); Janssen Scientific Affairs, LLC

Completed

Oral Risperidone Versus Injectable Paliperidone Palmitate for Treating First-Episode Schizophrenia

Schizophrenia (Recent-onset)

United States
Janssen-Cilag Ltd.

Completed

A Study of Transition to the Paliperidone Palmitate 3-Month Formulation In Participants With Schizophrenia Previously Stabilized on the Paliperidone Palmitate 1-Month Formulation

Schizophrenia

France, Germany, Spain, Israel, Malaysia, Turkey, Taiwan, Greece, Korea, Republic of, Russian Federation, Netherlands, United Kingdom, Croatia, Denmark, Saudi Arabia
University of Miami
Ortho-McNeil, Inc.

Withdrawn

Paliperidone Palmitate Efficacy and Safety in Bipolar Disorder Complicated by Alcoholism

Bipolar Disorder
Ortho-McNeil Janssen Scientific Affairs, LLC

Completed

Study to Measure the Safety of Paliperidone ER (Extended-release) in Patients With Liver Disease

Psychotic Disorders | Schizophrenia | Schizoaffective Disorder

United States
Janssen-Cilag G.m.b.H

Terminated

A Positron-Emission-Tomography (PET) Study to Measure the Blockade of Dopamine Receptors (D2) in Specific Areas of the Brain in Relation to the Plasma Concentrations of Paliperidone Extended Release (ER) and Oral Risperidone in Schizophrenia Patients and Healthy Controls

Schizophrenia

Germany
Uwakwe Emmanuel Chijioke

Recruiting

Metoclopramide Versus Hyoscine Butylbromide in Shortening Duration of First Stage of Labour

Duration of Labour

Nigeria
Ain Shams University
Armed Forces Hospitals, Southern Region, Saudi Arabia

Completed

Use of an Antiemetic to Shorten the Length of Labor in Nulliparous Women

Prolonged First Stage of Labor

Saudi Arabia
Janssen-Cilag International NV

Completed

Prevention of Relapse With Injectable Paliperidone Palmitate Versus Oral Antipsychotics (PROSIPAL)

Schizophrenia

France, Ukraine, United Kingdom, Germany, Taiwan, Spain, Poland, Bulgaria, Romania, Russian Federation, South Africa, Greece, Israel, Korea, Republic of, Belgium, Estonia, Turkey, Czech Republic, Austria, Hungary, Lithuania, Slovakia and more
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Safety and Pharmacokinetic Study of Paliperidone Palmitate in Patients With Schizophrenia

Schizophrenia

Poland, United States, Belgium, Taiwan, Spain, Malaysia, Korea, Republic of, Thailand, Slovakia, Croatia
Janssen Korea, Ltd., Korea

Completed

PaliperidoNe Extended-Release [ER] Dosing and Clinical Response in Acute Schizophrenia (PANDORA)

Schizophrenia

Korea, Republic of
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A 52-week, Open-label Extension Study Following a 6-week, Double-blind, Placebo- and Active- Controlled Study (R076477-SCH-303) to Evaluate the Safety and Tolerability of Paliperidone ER in Subjects With Schizophrenia

Schizophrenia
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of Paliperidone Enantiomer Disposition With Different Formulations and the Bioavailability of Immediate- and Extended-release Paliperidone

Schizophrenia
Pamukkale University

Completed

Efficacy and Akathisia Incidence of Slow Infusion Metoclopramide

Nausea | Akathisia
National University Hospital, Singapore

Completed

Metoclopramide to Aid Establishment of Breastfeeding:a Randomised Controlled Trial

Breastfeeding

Singapore
Luye Pharma Group Ltd.
Alliance for Clinical Trials in Oncology; Evolution Research Group

Completed

Evaluate the PK of LY03010 Process 1 and Process 2 Drug Product vs INVEGA SUSTENNA After Intramuscular Injection in Schizophrenia Patients

Schizophrenia Patients

United States
Janssen-Cilag International NV

Completed

A Survey to Collect Treatment Experience Feedback From Patients, Physicians, Nurses and Carers After Switching to Paliperidone Palmitate 3-monthly

Schizophrenia

Germany, Spain, Belgium, Hungary, France, Italy, United Kingdom
Janssen Cilag N.V./S.A.

Completed

IMPACT: A Study to Explore the Efficacy and Safety of Paliperidone ER in Patients With Acute Agitation

Psychomotor Agitation | Acute Disease

Belgium
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Long-term Safety and Tolerability and the Long-term Effectiveness of Extended-release Oral Paliperidone in Patients Diagnosed With Schizophrenia

Schizophrenia
Xijing Hospital
Xi'an Central Hospital; First Affiliated Hospital Xi'an Jiaotong University; Tang-Du... and other collaborators

Terminated

Optimizing Early Enteral Nutrition in Severe Stroke (OPENS)

Dysphagia | Acute Stroke | Severe Stroke

China
Korea Otsuka Pharmaceutical Co., Ltd.

Recruiting

A Study of Abilify® Tablet(Aripiprazole) as an Adjunctive Treatment in the Bipolar Depression (APOLLO)

Depression, Bipolar

Korea, Republic of
Otsuka Pharmaceutical Co., Ltd.

Completed

Bioequivalence Between Single Administration of ASC-01 (Aripiprazole/Sertraline Combination Drug) and Concomitant Single Administration of Aripiprazole and Sertraline, and Food Effect on Pharmacokinetics of ASC-01 in Healthy Male Adults

Healthy Male Adults

Japan
UMC Utrecht

Completed

European Long-acting Antipsychotics in Schizophrenia Trial (EULAST)

Schizophrenia

Netherlands, Norway, Austria, Belgium, Bulgaria, Czechia, Denmark, Germany, Greece, Hungary, Israel, Italy, Poland, Romania, Spain, United Kingdom
Northwell Health

Terminated

1/2-MC4R Genotype and Pediatric Antipsychotic Drug- Induced Weight Gain

High Risk MC4R Genotype | Low Risk MC4R Genotype | One Week or Less Antipsychotic Lifetime Exposure

United States

Search clinical trials for: Dopamine D2 Receptor Antagonists

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Türkiye

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations