Search clinical trials for: empagliflozin and metformin

Total 269887 results

Fasa University of Medical Sciences
Shiraz University of Medical Sciences

Completed

Effects of Metformin Plus Simvastatin on Polycystic Ovarian Syndrome (PCOS): A Prospective, Randomized, Double-Blind, Placebo-Controlled Study

Polycystic Ovary Syndrome

Iran, Islamic Republic of
Steno Diabetes Center Copenhagen
Bayer; AstraZeneca; Rigshospitalet, Denmark; The Novo Nordic Foundation

Completed

The PRE-D Trial: Effect of Dapagliflozin, Metformin and Physical Activity in Pre-diabetes

Obesity | Prediabetic State

Denmark
Shionogi

Completed

Study to Assess Safety and Pharmacokinetics of Double-Blind S-707106 Alone and in Combination With Open-Label Metformin in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
NuSirt Biopharma

Completed

An Extension Protocol to Evaluate Dose Comparisons of Leucine-Metformin Combinations in Type 2 Diabetic Patients

Type 2 Diabetes Mellitus

United States
Mitsubishi Tanabe Pharma Corporation

Completed

Efficacy and Safety of MP-513 in Combination With Metformin in Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus

Poland, United Kingdom, Germany, Romania, Hungary, Denmark, Lithuania
University Hospital, Basel, Switzerland

Completed

L-citrulline and Metformin in Becker's Muscular Dystrophy

Becker's Muscular Dystrophy (BMD)

Switzerland
EMS

Not yet recruiting

Efficacy and Safety of Piemonte Association in the Treatment of Type II Diabetes Mellitus (PIEMONTE)

Type II Diabetes
Bristol-Myers Squibb

Completed

Phase 4: Investigational Study to Evaluate Metformin XR Monotherapy Versus Metformin IR Monotherapy in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus

South Africa, United States, Canada, Puerto Rico, Hungary, Germany, Czechia, Poland, Romania, United Kingdom
Hoffmann-La Roche

Completed

A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin Alone

Diabetes Mellitus Type 2

United States, Mexico, Argentina
Hadassah Medical Organization

Withdrawn

Open-label Crossover Metformin Gum Versus Tablet in Healthy Volunteers

Healthy

Israel
Seoul National University Hospital

Unknown

Effect of Dapagliflozine on Systemic and Renal Endothelial Function

Type 2 Diabetes | Endothelial Function

Korea, Republic of
Geropharm

Completed

Bioequivalence Study of Metformin 750 mg Tablets XR Versus Glucophage® Long 750 mg Tablets XR In Normal Healthy Subjects Under Fasting and Fed Conditions

Bioequivalence

Russian Federation
Charles University, Czech Republic

Completed

Effect of Metformin on Exercise-induced Lipolysis

Diabetes Mellitus, Type 2

Czechia
Oslo University Hospital
Vestre Viken Hospital Trust; University of Oslo; The Research Council of Norway; University Hospital, Akershus and other collaborators

Recruiting

Effects of Glucose Lowering Agents in South Asian Women With Impaired Glucose Tolerance or Impaired Fasting Glucose (DIASA3)

Glucose Metabolism Disorders | Impaired Glucose Tolerance | Insulin Sensitivity

Norway
Azienda Ospedaliero-Universitaria di Parma

Active, not recruiting

Managing DIabetes Remission After Combined Therapy in EarLy Stage of DiabetEs (MIRACLE)

Newly Diagnosed Type 2 Diabetes

Italy
AstraZeneca
Bristol-Myers Squibb

Completed

A Phase III Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes Who Are Not Well Controlled With Diet and Exercise

Type 2 Diabetes

United States, Canada, Mexico, Russian Federation
German Diabetes Center
Yale University

Enrolling by invitation

"The Role of the Liver for Interorgan Metabolic Crosstalk in Type 2 Diabetes"

Type2 Diabetes

Germany
RenJi Hospital

Completed

The Effect of Metformin on Reducing Lupus Flares (Met Lupus)

Systemic Lupus Erythematosus

China
Laboratorios Silanes S.A. de C.V.

Completed

Metformin Glycinate on Metabolic Control and Inflammatory Mediators in Type 2 Diabetes (COMET)

Type 2 Diabetes

Mexico
Milton S. Hershey Medical Center

Terminated

Metformin for the Treatment of Premature Pubarche in Girls

Premature Pubarche

United States
Woman's
Pfizer; American Cancer Society, Inc.; Our Lady of the Lake Regional Medical...

Withdrawn

Metformin Use to Reduce Disparities in Newly Diagnosed Breast Cancer (METBC)

Insulin Resistance | Breast Cancer Stage | Racial Bias

United States
The Affiliated Nanjing Drum Tower Hospital of Nanjing...
Nanjing First Hospital, Nanjing Medical University; Wuxi People's Hospital; Changzhou... and other collaborators

Recruiting

Effects of Liraglutide, Empagliflozin and Linagliptin on the Cognitive Function in T2DM Patients With Mild Cognitive Impairment: a Multicenter, Randomized, Parallel Controlled Clinical Trial

Type 2 Diabetes Mellitus | Mild Cognitive Impairment

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

The Drug-drug Interaction of SHR3824 and Metformin

Type 2 Diabetes
University of Texas Southwestern Medical Center

Completed

Type 2 Diabetes and Ambulatory Surgery Patients (Diabetes)

Diabetes Type 2
Garvan Institute of Medical Research
Weizmann Institute of Science

Active, not recruiting

Personalised Medicine in Pre-diabetes and Early Type 2 Diabetes (PREDICT)

Type 2 Diabetes Mellitus | Pre Diabetes

Australia
University of Virginia
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Effects of Empagliflozin on Cardiac Microvasculature and Insulin Sensitivity in Subjects With Type 2 Diabetes (EJB051)

Type2 Diabetes | Insulin Sensitivity

United States
Boehringer Ingelheim
Eli Lilly and Company

Completed

A Study to Test the Effect of Empagliflozin in Patients Who Are in Hospital for Acute Heart Failure

Heart Failure

United States, Denmark, Canada, Belgium, China, Italy, Germany, Spain, Netherlands, Hungary, Japan, Norway, Poland, Sweden, Czechia
Kobe University
Boehringer Ingelheim

Active, not recruiting

A Extension Study of Empagliflozin in Patients With Refractory Diabetes Mellitus With Insulin Resistance ( EMPIRE-02 ) (EMPIRE-02)

Insulin Resistance - Type A | Insulin Resistance - Type B | Lipoatrophic Diabetes Mellitus | Insulin Resistance Syndrome

Japan
British University In Egypt

Completed

Pharmacokinetic Evaluation of Empagliflozin

Diabetes Mellitus
Brian Zuckerbraun

Completed

Effects of Metformin in a Non-Diabetic Patient Population

Inflammatory Response

United States
GlaxoSmithKline

Terminated

An Open Study to Evaluate Whether Pack Size Affects Compliance of Metformin Treatment in Subjects With Type II Diabetes

Diabetes Mellitus, Type 2

Argentina
Dong-A Pharmaceutical Co., Ltd.

Completed

Pharmacokinetic/Pharmacodynamic Drug-drug Interaction of DA-1229 and Metformin After Oral Administration in Healthy Male Subjects

Type 2 Diabetes Mellitus

Korea, Republic of
AstraZeneca

Not yet recruiting

Efficacy, Safety and Tolerability of Balcinrenone/Dapagliflozin Compared to Dapagliflozin in Adults With Chronic Kidney Disease. (MIRO-CKD)

Chronic Kidney Disease

United States, Austria, Italy, Spain, Canada, Malaysia, Taiwan, Poland, Bulgaria
Novo Nordisk A/S

Completed

Efficacy and Safety of Oral Semaglutide Versus Empagliflozin in Subjects With Type 2 Diabetes Mellitus (PIONEER 2)

Diabetes Mellitus, Type 2 | Diabetes

United States, Croatia, Italy, Poland, Russian Federation, Spain, Greece, Serbia, Thailand, Brazil, Hungary, Argentina
Jiangsu HengRui Medicine Co., Ltd.

Completed

Efficacy and Safety Study of SP2086 in Combination With Metformin in Patients With Type 2 Diabetes

Type 2 Diabetes

China
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Phase III Study of SP2086 in Combination With Metformin in Patients With Type 2 Diabetes

Type 2 Diabetes

China
Shanghai Yinnuo Pharmaceutical Technology Co.,...

Active, not recruiting

A Study of Efficacy and Safety of Supaglutide in Type 2 Diabetes Patients On Metformin Treatment

Type2 Diabetes

China
NuSirt Biopharma

Completed

Dose Comparisons of Leucine-Metformin Combinations on Blood Glucose Levels In Type 2 Diabetic Patients

Type 2 Diabetes Mellitus

United States
Elcelyx Therapeutics, Inc.

Completed

Assessing the PK and Effect on Glucose and GI Hormone Concentrations of Metformin Delayed-Release in Subjects With T2DM

Type 2 Diabetes Mellitus

United States
Haisco Pharmaceutical Group Co., Ltd.
The Fourth Hospital of Hebei Medical University

Recruiting

A Study Evaluating Drug-Drug Interaction (DDI) Between HSK16149 Capsules and Metformin Hydrochloride Tablets

Diabetic Neuropathies | Diabetic Neuropathy Peripheral

China
Central Hospital, Nancy, France

Not yet recruiting

Effect at 3 Months of Early Empagliflozin Initiation in Cardiogenic Shock Patients on Mortality, Rehospitalization, Left Ventricular Ejection Fraction and Renal Function. (EMPASHOCK)

Cardiogenic Shock

France
University of Sao Paulo

Recruiting

Effect of Empagliflozin on Ventricular Repolarization. (EMPATHYHEART)

Diabetes Mellitus, Type 2 | Coronary Heart Disease | Arrythmia, Cardiac

Brazil
Boehringer Ingelheim
Eli Lilly and Company

Active, not recruiting

Post Marketing Surveillance (PMS) of JARDIANCE in Chronic Heart Failure (CHF)

Heart Failure

Japan
Vanderbilt University Medical Center

Completed

SGLT2 Inhibitor Effects on Inflammation and Heart Disease in Obesity Pilot

Obesity | Pre-diabetes

United States
Stanford University

Completed

Empagliflozin in Diuretic Refractory Ascites (DRAin-Em 01)

Liver Cirrhosis | Cirrhosis | Ascites | Ascites Hepatic | Sodium-Glucose Transporter 2 Inhibitors

United States
Zhijun Sun

Enrolling by invitation

EMPAGUM: Effects of Empagliflozin on Gut Microbiota in Heart Failure With a Preserved Ejection Fraction

Heart Failure | Heart Failure With Preserved Ejection Fraction

China
University Hospital, Basel, Switzerland

Completed

Effects of the SGLT2-inhibitor Empagliflozin on Patients With Chronic SIADH - the SANDx Study (SANDx)

Hyponatremia | SIAD - Syndrome of Inappropriate Antidiuresis

Switzerland
Kobe University
Boehringer Ingelheim

Active, not recruiting

A Study of Empagliflozin in Patients With Refractory Diabetes Mellitus With Insulin Resistance (EMPIRE-01)

Insulin Resistance - Type A | Insulin Resistance - Type B | Lipoatrophic Diabetes Mellitus | Insulin Resistance Syndrome

Japan
Rajaie Cardiovascular Medical and Research Center
Tehran Heart Center

Recruiting

Empagliflozin to Prevent Post-Operative Atrial Fibrillation (EMPOAF)

CABG | Post-operative Atrial Fibrillation

Iran, Islamic Republic of
Yale University

Recruiting

Effects of Acute and Chronic Empagliflozin Heart Failure (EMPA HF)

Heart Failure

United States

Search clinical trials for: empagliflozin and metformin

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