Search clinical trials for: Endothelial Keratoplasty

Total 827 results

Prince of Songkla University

Completed

Intraocular Pressure Change Following Intravitreal Injection of Anti-vascular Endothelial Growth Factor Agent

Intraocular Pressure

Thailand
Bettina Mittendorfer

Recruiting

Routine Validation and Reproducibility Testing of Laboratory Measures and Research Techniques Used for Metabolism Research (VAL) (VAL)

Obesity

United States
Shandong Boan Biotechnology Co., Ltd

Completed

Pharmacokinetic Characteristics, Safety, Tolerability and Immunogenicity of LY01008 and Avastin in Healthy Chinese Male Subjects

Metastatic Colorectal Cancer | Non Small Cell Lung Cancer Metastatic | Non Small Cell Lung Cancer Recurrent

China
National Cancer Institute (NCI)

Completed

VEGF Trap in Treating Patients With Recurrent Malignant Gliomas That Did Not Respond to Temozolomide

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
Huabo Biopharm Co., Ltd.

Completed

A Study of Single Intravitreal Injection HB002.1M in Subjects With Neovascular Age-Related Macular Degeneration

Neovascular Age-Related Macular Degeneration

China
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Atrasentan in Treating Patients With Locally Recurrent or Metastatic Kidney Cancer

Kidney Cancer

United States
Abbott

Completed

Atrasentan in Treating Patients With Prostate Cancer

Prostate Cancer

United States
National Cancer Institute (NCI)

Completed

Atrasentan in Treating Patients With Progressive or Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)

Completed

VEGF Trap in Treating Patients With Metastatic Breast Cancer

Metastatic Breast Cancer | Stage IV Breast Cancer | Recurrent Breast Cancer

United States
Abbott

Completed

Study of Atrasentan in Men With Non-Metastatic, Hormone-Refractory Prostate Cancer

Prostatic Neoplasms

Canada, United States, Spain, Belgium, Australia, Italy, United Kingdom, Germany, France, Sweden, South Africa, Netherlands, Ireland, New Zealand, Greece, Poland, Austria
Jaeb Center for Health Research
National Eye Institute (NEI); National Institutes of Health (NIH); Regeneron...

Completed

Anti-VEGF vs. Prompt Vitrectomy for VH From PDR (AB)

Proliferative Diabetic Retinopathy | Vitreous Hemorrhage

United States, Canada
Kim's Eye Hospital
Bayer

Completed

Intravitreal Aflibercept for Submacular Hemorrhage

Exudative Age-related Macular Degeneration

Korea, Republic of
National Cancer Institute (NCI)

Completed

VEGF Trap in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

Recurrent Melanoma | Stage IV Melanoma | Ciliary Body and Choroid Melanoma, Medium/Large Size | Iris Melanoma | Metastatic Intraocular Melanoma | Recurrent Intraocular Melanoma | Stage III Melanoma | Extraocular Extension Melanoma

United States
National Cancer Institute (NCI)

Terminated

Aflibercept in Treating Patients With Myelodysplastic Syndromes

Chronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndromes | Secondary Myelodysplastic Syndromes | Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative | Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable | de Novo Myelodysplastic Syndromes

United States
Massachusetts General Hospital
Spina, Stefano, M.D., Massachusetts General Hospital; Marrazzo, Francesco,... and other collaborators

Recruiting

Effects of Nitric Oxide on the Endothelium During Hemolysis.

Cardiovascular Diseases | Endothelial Dysfunction | Cardiovascular Risk Factor | Hemolysis Intravascular

United States
Actelion

Completed

Clinical Study to Assess the Efficacy and Safety of Macitentan in Patients With Pulmonary Hypertension After Left Ventricular Assist Device Implantation (SOPRANO)

Pulmonary Hypertension

United States
Actelion

Completed

Clinical Study to Investigate Effect of Macitentan on Riociguat Pharmacokinetics

Healthy Subjects

Germany
Actelion

Completed

The Efficacy and Safety of Initial Triple Versus Initial Dual Oral Combination Therapy in Patients With Newly Diagnosed Pulmonary Arterial Hypertension (TRITON)

Pulmonary Arterial Hypertension

United States, Spain, Denmark, Canada, Germany, United Kingdom, Belgium, Austria, Netherlands, Australia, France, Ireland, Sweden, Italy, Switzerland
Jae Hoon Lee
Gachon University Gil Medical Center; Daejeon University

Unknown

Efficacy and Safety of HPC-03 for Postmenopausal Symptom

Postmenopausal Period

Korea, Republic of
Radboud University Medical Center
UMC Utrecht; Catharina Ziekenhuis Eindhoven; Maasstad Hospital

Not yet recruiting

Efficacy of Endothelin Receptor Antagonism in Coronary Artery Spasm (EDIT-CAS)

Coronary Spasm

Netherlands
Xuzhou Medical University

Unknown

the Effect of Tracleer on Tourniquet-associated Hypertension

Hypertension | Tourniquets | Bosentan

China
AbbVie (prior sponsor, Abbott)

Completed

A Prospective, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate Efficacy and Safety of Atrasentan, Including Thoracic Bioimpedance, in Type 2 Diabetic Subjects With Nephropathy

Diabetic Nephropathy | Chronic Kidney Disease

United States
Abbott

Completed

A Long Term Safety Study With Atrasentan

Adenocarcinoma | Prostate Cancer

Canada, United States, France, Netherlands, United Kingdom
Glostrup University Hospital, Copenhagen

Unknown

Endothelin-1 as a Potential Trigger of Migraine Aura

Migraine With Aura

Denmark
Cedars-Sinai Medical Center
University of California, San Francisco

Completed

Vascular Aging in Flight Attendants With Occupational Secondhand Smoke Exposure

Secondhand Smoking | Vascular Aging

United States
AbbVie

Terminated

Study Of Diabetic Nephropathy With Atrasentan (SONAR)

Diabetic Nephropathy
Pfizer

Completed

Anti-angiogenesis Agent AG-013736 in Patients With Metastatic Renal Cell Carcinoma

Kidney Neoplasms

United States, Germany, France
AbbVie

Completed

Atrasentan Spermatogenesis and Testicular Function

Diabetes | Nephropathy

United States, Germany, Italy, Spain
Janssen Pharmaceutical K.K.

Completed

A Study of Macitentan, in Healthy Japanese Male Participants

Healthy

Japan
University of Exeter
North Bristol NHS Trust; Royal Devon and Exeter NHS Foundation Trust; Royal United...

Enrolling by invitation

PRospective Evaluation of Interstitial Lung DIsease Progression With Quantitative CT (PREDICT-ILD)

Interstitial Lung Disease

United Kingdom
Janssen Research & Development, LLC

Completed

A Study of Macitentan and Tadalafil as a Fixed Dose Combination and the Free Combination in Healthy Adult Participants

Healthy

United States
Actelion

Terminated

Clinical Study on the Safety and Tolerability of Macitentan in Combination With Dose-dense Temozolomide in Patients With Recurrent Glioblastoma

Glioblastoma

United States
AbbVie (prior sponsor, Abbott)

Completed

Evaluate the Efficacy and Safety of Once Daily Administration of Atrasentan Tablets (Low and High) Compared to Placebo in Reducing Residual Albuminuria in Type 2 Diabetic Patients With Nephropathy Who Are Treated With the Maximum Tolerated Labeled Dose of a Renin Angiotensin System (RAS) Inhibitor (RADAR)

Diabetic Nephropathy | Chronic Kidney Disease

United States, Canada, Puerto Rico, Taiwan
Mayo Clinic
National Institutes of Health (NIH)

Completed

Correlation of Endothelial Function and Early Coronary Artery Disease in Humans

Endothelial Dysfunction

United States
Shanghai Henlius Biotech

Completed

Evaluate the Safety and Efficacy of HLX04-O in Subjects With wAMD

Age Related Macular Degeneration

China
Mayo Clinic
National Cancer Institute (NCI)

Terminated

Lenalidomide and AT-101 in Treating Patients With Relapsed B-Cell Chronic Lymphocytic Leukemia

Recurrent Chronic Lymphocytic Leukemia

United States
Chinook Therapeutics U.S., Inc.

Active, not recruiting

Atrasentan in Patients With Proteinuric Glomerular Diseases (AFFINITY)

Diabetic Kidney Disease | Focal Segmental Glomerulosclerosis | Immunoglobulin A Nephropathy | IgA Nephropathy | Diabetic Nephropathy Type 2 | Alport Syndrome

United States, Spain, Korea, Republic of, Australia, Italy, United Kingdom
Ohio State University Comprehensive Cancer Center

Active, not recruiting

Impact of E-cigarette Use on the Body

Cigarette Smoking-Related Carcinoma

United States
Actelion

Terminated

Clinical Study Evaluating the Effects of First-line Oral cOmbination theraPy of maciTentan and tadalafIl in Patients With Newly Diagnosed pulMonary Arterial Hypertension (OPTIMA) (OPTIMA)

Pulmonary Arterial Hypertension

France
Beni-Suef University

Unknown

Maternal Serum Vascular Endothelial Growth Factor in Pregnant Women With Foetal Growth Restriction (VEGF in FGR)

Foetal Growth Restriction

Egypt
Genor Biopharma Co., Ltd.

Unknown

Clinical Trial in Chinese Healthy Volunteers of GB222

Non-small Cell Lung Cancer

China
IRCCS Azienda Ospedaliero-Universitaria di Bologna
University of Bologna

Not yet recruiting

Multiparametric Assessment of Maternal Vascular Function in the Prediction of Hypertensive Disorders of Pregnancy (EDIPE)

Preeclampsia | Hypertensive Disorder of Pregnancy

Italy
University Hospital, Rouen

Completed

Role of Endothelin-1 in Flow-mediated Dilatation (Endothelin)

Healthy Conditions

France
University of Modena and Reggio Emilia

Unknown

Evaluation of the Effect of Cataract Surgery on Cognitive Function in Very Elderly Patients

Dementia | Cataract | Cataract Senile | Mild Cognitive Impairment | Post-Op Complication | Delirium in Old Age | Delirium Confusional State | Cataract in Old Age

Italy
Instituto de Investigación Sanitaria de la Fundación...

Recruiting

Hemodynamic and Functional Characteristics of the Cerebral Circulation in Obesity (HemOB)

Cerebral Arterial Diseases

Spain
Chinook Therapeutics, Inc.

Recruiting

Randomized, Double-blind, Placebo-controlled, Crossover Study of Atrasentan in Subjects With IgA Nephropathy (ASSIST)

Immunoglobulin A Nephropathy | IgA Nephropathy

Spain, United States, Australia, Korea, Republic of, Brazil, Malaysia
University of Edinburgh
Encysive Pharmaceuticals

Completed

Role of Endothelin-A (ETA) and Endothelin-B (ETB) Receptors in the Vasodilatory Response to Endothelin-3 (ET-3)

Pulmonary Arterial Hypertension | Vasodilation | Vasoconstriction

United Kingdom
Actelion

Completed

A Study to Compare the Macitentan-tadalafil Fixed Dose Combination Tablet Relative to the Concomitant Administration of the Reference Tablets of Macitentan and Tadalafil in Healthy Subjects

Healthy Subjects

Germany
National Cancer Institute (NCI)

Completed

Ziv-Aflibercept in Treating and Computed Tomography Perfusion Imaging in Predicting Response in Patients With Pancreatic Neuroendocrine Tumors That Are Metastatic or Cannot Be Removed by Surgery

Pancreatic Neuroendocrine Carcinoma | Multiple Endocrine Neoplasia Type 1

United States
I.M. Sechenov First Moscow State Medical University

Recruiting

Cardiovascular Diagnostic in Assessment of Risk HDS and HCT in Patients With Haemoblasts.

Cardiotoxicity

Russian Federation

Search clinical trials for: Endothelial Keratoplasty

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