Search clinical trials for: Ethambutol

Total 95 results

Pharmacia

Completed

A Study of Rifabutin, Used Alone or With Ethambutol in the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in Patients With AIDS

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Texas Tech University Health Sciences Center
University of Texas Southwestern Medical Center; National Center for Research...

Completed

Effect of Weight and/or Obesity on Ethambutol Drug Concentrations

Obesity | Tuberculosis

United States
Tuberculosis Research Centre, India
United States Agency for International Development (USAID)

Completed

Preventive Therapy for Tuberculosis in HIV Infected Persons

Tuberculosis | Human Immunodeficiency Virus

India
Pfizer

Completed

A Randomized, Double-Blind, Comparative Study of Azithromycin Versus Clarithromycin in Combination With Ethambutol for the Treatment of Disseminated Mycobacterium Avium Complex (MAC) Infection in AIDs Patients

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluation of Treatment for Mycobacterium Avium Complex (MAC) Infection in HIV-Infected Patients

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Spero Therapeutics

Completed

A Study to Evaluate the Effect of Co-administration on the Pharmacokinetics of SPR720, Azithromycin, and Ethambutol in Healthy Participants

Healthy Volunteers

United States
Pharmacia

Completed

A Three-Arm Comparative Trial for the Treatment of MAC Bacteremia in AIDS: A Clarithromycin/Ethambutol Regimen Containing Rifabutin (450 Mg) or Rifabutin (300 Mg) or Placebo

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Abbott

Completed

The Safety and Effectiveness of Clarithromycin Plus Ethambutol Used With or Without Clofazimine in the Treatment of MAC in Patients With AIDS

HIV Infections | Mycobacterium Avium-intracellular Infection

United States, Puerto Rico
Anderson Clinical Research
Hoechst Marion Roussel

Completed

Tolerance, Safety, and Activity of Rifapentine Alone and in Combination Therapy in AIDS Patients With Mycobacterium Avium Complex Bacteremia.

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

Study of Four Different Treatment Approaches for Patients Who Have Mycobacterium Avium Complex Disease (MAC) Plus AIDS

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Beijing Chest Hospital
The First Affiliated Hospital with Nanjing Medical University; Anhui Chest... and other collaborators

Recruiting

Efficacy Safety BaiDiZiYin ShenQiYiFei Adjunctive Treatments Pulmonary Tuberculosis

Tuberculosis | Treatment | Adjuvant

China
University of Zurich

Recruiting

Safety and Tolerability of Chlorquine in Addition to Anti-tuberculosis Therapy

Tuberculosis Infection

Switzerland
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Completed

Use of Pyridostigmine for Constipation in Diabetics

Diabetes Mellitus | Constipation | Gastric Emptying | Colonic Transit

United States
Tuberculosis Research Centre, India

Completed

Comparing Daily vs Intermittent Regimen of ATT in HIV With Pulmonary Tuberculosis

HIV Infection | Pulmonary TB

India
British Thoracic Society

Completed

Clarithromycin v Ciprofloxacin Added to Rifampicin + Ethambutol, for Opportunist Mycobacterial Pulmonary Disease

Pulmonary Diseases

United Kingdom
Insmed Incorporated

Completed

Validation of Patient Reported Outcome Measures in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium Complex (ARISE)

Mycobacterium Infections, Nontuberculous

United States, Argentina, Australia, Austria, Canada, Chile, Denmark, Germany, Israel, Italy, Korea, Republic of, New Zealand, Spain, Taiwan
Seoul National University Hospital
Pfizer; Seoul National University Bundang Hospital; SMG-SNU Boramae Medical Center and other collaborators

Unknown

Linezolid Instead of Ethambutol in Treatment of Drug-susceptible Tuberculosis

Pulmonary Tuberculosis Without Resistance to Rifampicin

Korea, Republic of
All India Institute of Medical Sciences, New Delhi
Ministry of Health & Family Welfare, India

Completed

Efficacy of Thrice Weekly Directly Observed Treatment, Short-course (DOTS) in HIV-associated Tuberculosis

HIV Infections | Acquired Immunodeficiency Syndrome | Tuberculosis

India
Shanghai Pulmonary Hospital, Shanghai, China
Centers for Disease Control and Prevention; Zhejiang University; Jiangsu Province... and other collaborators

Unknown

Research on New Regimens for Retreatment Pulmonary Tuberculosis

Reinfection Pulmonary Tuberculosis

China
National Institute of Allergy and Infectious Diseases...

Completed

A Comparison of Three Drug Combinations Containing Clarithromycin in the Treatment of Mycobacterium Avium Complex (MAC) Disease in Patients With AIDS

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States, Tanzania
National Institute of Allergy and Infectious Diseases...

Completed

Effectiveness of Anti-HIV Therapy (HAART) in HIV-Infected Patients With Tuberculosis

HIV Infections | Tuberculosis

United States
University of Minnesota
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Strategies and Treatments for Respiratory Infections & Viral Emergencies (STRIVE): Shionogi Protease Inhibitor (Ensitrelvir)

COVID-19

United States, Singapore, Japan, Ukraine, Georgia, Korea, Republic of, Australia, Denmark, Thailand, Greece, South Africa, Germany, Uganda, Spain, Puerto Rico, Argentina
University of Oxford

Completed

PK Study of Anti-TB Drugs

Tuberculosis

Thailand
Makerere University

Unknown

Evaluation of the Pharmacokinetics of Antituberculosis Drugs and Tuberculosis Treatment Outcomes (SOUTH)

AIDS With Tuberculosis

Uganda
Insmed Incorporated

Recruiting

Study to Evaluate ALIS (Amikacin Liposome Inhalation Suspension) in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium Complex (ENCORE)

Mycobacterium Infections, Nontuberculous

Belgium, New Zealand, United Kingdom, United States, Argentina, Australia, Austria, Canada, Chile, Denmark, France, Germany, Greece, Hungary, Israel, Italy, Japan, Korea, Republic of, Poland, Spain, Taiwan, Turkey, Portugal
Laboratorios Silanes S.A. de C.V.

Completed

Safety of doTBal® in Patients With Tuberculosis: Conduction of an Intensive Pharmacovigilance Program

Tuberculosis

Mexico
National Institute of Allergy and Infectious Diseases...

Completed

Phase 2a EBA Trial of AZD5847

Tuberculosis

South Africa
Tuberculosis Research Centre, India

Unknown

Short Course Intermittent Regimens for the Treatment of HIV-Associated Tuberculosis

Tuberculosis | Human Immunodeficiency Virus Infections

India
National Jewish Health

Completed

Phase II Study of Amithiozone (Thiacetazone) for Patients With Mycobacterium Avium Complex Pulmonary Disease

Mycobacterium Avium-intracellulare Infection
Global Alliance for TB Drug Development

Completed

A Phase 2 Trial to Evaluate the Efficacy and Safety of Linezolid in Tuberculosis Patients. (LIN-CL001)

Pulmonary Tuberculosis

South Africa
National Institute of Allergy and Infectious Diseases...

Completed

Using Biomarkers to Predict TB Treatment Duration

Pulmonary Tuberculosis

South Africa
Institute of Tropical Medicine, Belgium
Damien Foundation

Active, not recruiting

Novel Triple-dose Tuberculosis Retreatment Regimen (Tri-Do-Re)

Tuberculosis | Pulmonary Tuberculosis | Multidrug-resistant Tuberculosis | Resistance to Tuberculostatic Drugs

Niger
Yuria-Pharm

Terminated

Efficacy and Safety of Intravenous Treatment of Tuberculosis

Tuberculosis, Pulmonary

Ukraine
Vanderbilt University

Completed

Investigation of the Efficacy of Antibiotics on Pulmonary Sarcoidosis (CLEAR Lung)

Pulmonary Sarcoidosis | Lung Function

United States
Centers for Disease Control and Prevention
Bayer; Global Alliance for TB Drug Development

Completed

TBTC Study 28: Moxifloxacin Versus Isoniazid for TB Treatment

Tuberculosis

Uganda, United States, South Africa, Canada, Brazil, Spain
National Institute of Allergy and Infectious Diseases...

Recruiting

Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents With Tuberculous Meningitis

Tuberculous Meningitis

South Africa, Zimbabwe, India, Kenya, Malawi, Mexico, Peru, Brazil, Philippines, Tanzania, Thailand, Vietnam
University Hospital, Linkoeping
Linkoeping University

Suspended

Drug Exposure and Safety of a Shorter Tuberculosis Treatment Based on High-Dose Rifampicin and Pyrazinamide (HIGHSHORT-RP)

Tuberculosis, Pulmonary

Sweden
National Institute of Allergy and Infectious Diseases...

Completed

A Phase II/III Trial of Rifampin, Ciprofloxacin, Clofazimine, Ethambutol, and Amikacin in the Treatment of Disseminated Mycobacterium Avium Infection in HIV-Infected Individuals.

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Johns Hopkins University
Universidade Federal do Rio de Janeiro

Terminated

Rifapentine Plus Moxifloxacin for Treatment of Pulmonary Tuberculosis

Tuberculosis

Brazil
University of California, Davis
Unilever R&D

Completed

Feeding Trial to Determine How Combinations of Different Dietary Bioactive Ingredients Influence High Density Lipoprotein (HDL) Metabolism (HDL)

Dyslipidemia

United States
Global Alliance for TB Drug Development

Completed

Trial to Evaluate the Efficacy, Safety and Tolerability of BPaMZ in Drug-Sensitive (DS-TB) Adult Patients and Drug-Resistant (DR-TB) Adult Patients

Tuberculosis | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Tuberculosis, MDR | Drug-Resistant Tuberculosis

Tanzania, Georgia, Russian Federation, Brazil, Malaysia, Philippines, South Africa, Uganda
Michael Hoelscher
Radboud University Medical Center; German Federal Ministry of Education and... and other collaborators

Completed

BTZ-043 - Multiple Ascending Dose (MAD) to Evaluate Safety, Tolerability and Early Bactericidal Activity (EBA)

Pulmonary Tuberculoses | Other Specified Pulmonary Tuberculosis

South Africa
Tuberculosis Research Centre, India
National Institutes of Health (NIH)

Completed

Latency in Pulmonary Tuberculosis

Pulmonary Tuberculosis

India
Global Alliance for TB Drug Development
Sanofi; University College, London; European and Developing Countries Clinical... and other collaborators

Completed

Controlled Comparison of Two Moxifloxacin Containing Treatment Shortening Regimens in Pulmonary Tuberculosis (REMoxTB)

Pulmonary Tuberculosis

China, Zambia, Tanzania, India, Kenya, Malaysia, Mexico, South Africa, Thailand
National Institute of Allergy and Infectious Diseases...

Completed

Metabolism of Antituberculosis Drugs in HIV-Infected Persons With Tuberculosis

HIV Infections | Tuberculosis

United States
Fifth Affiliated Hospital, Sun Yat-Sen University

Not yet recruiting

Efficacy and Safety of Isoniazid, Rifampicin and Moxifloxacin for the Intensive Phase of Initial Therapy of PTB

Pulmonary Tuberculosis

China
Global Alliance for TB Drug Development

Completed

A Phase 2 to Evaluate the Efficacy, Safety and Tolerability of Combinations of Bedaquiline, Moxifloxacin, PA-824 and Pyrazinamide in Adult Subjects With Drug-Sensitive or Multi Drug-Resistant Pulmonary Tuberculosis. (NC-005)

Tuberculosis

Tanzania, South Africa, Uganda
Global Alliance for TB Drug Development

Completed

Shortening Treatment by Advancing Novel Drugs (STAND)

Tuberculosis, Pulmonary, Drug Sensitive | Tuberculosis, Pulmonary, Multi Drug-resistant

South Africa, Zambia, Georgia, Philippines, Kenya, Malaysia, Tanzania, Uganda
Vanderbilt University

Completed

Trial of Antimycobacterial Therapy in Sarcoidosis (CLEAR)

Sarcoidosis

United States
Michael Hoelscher
Radboud University Medical Center; German Federal Ministry of Education and... and other collaborators

Completed

Evaluation of SQ109, High-dose Rifampicin, and Moxifloxacin in Adults With Smear-positive Pulmonary TB in a MAMS Design

Tuberculosis, Pulmonary

South Africa, Tanzania

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