Search clinical trials for: Ezetimibe Statin (simvastatin, atorvastatin, or pravastatin)

Total 95 results

Organon and Co
Merck Sharp & Dohme LLC

Completed

Comparison of Ezetimibe Added to Ongoing Statin Therapy Versus Doubling the Dose of Statin in the Treatment of Hypercholesterolemia (P04355)

Hypercholesterolemia
Eli Lilly and Company

Completed

A Study of LY3015014 in Participants With High Cholesterol

Hypercholesterolemia

Poland, Netherlands, United States, Denmark, Canada, Japan, Czechia, Puerto Rico
Hospital Israelita Albert Einstein
Novartis; epHealth

Completed

Real World Evidence Study of Statin Use in Brazil (RWE-Statins)

Myocardial Infarction | Cardiovascular Diseases | Stroke | Hypertension | Diabetes Mellitus | Dyslipidemias

Brazil
Organon and Co

Completed

A 12 Week Study of MK0653A in Patients Who Have Been Hospitalized for a Possible Heart Problem (0653A-808)

Hypercholesterolemia
Organon and Co

Completed

Ezetimibe/Simvastatin (MK-0653A) Versus Rosuvastatin Versus Doubling Statin Dose in Participants With Cardiovascular Disease and Diabetes Mellitus (MK-0653A-133)(COMPLETED)

Diabetes Mellitus | Cardiovascular Disorder
University of Cologne
German Federal Ministry of Education and Research

Completed

Statin Recapture Therapy Before Coronary Artery Bypass Grafting (StaRT-CABG)

Coronary Artery Disease

Germany
Rockefeller University
Cornell University; Adelphi University

Terminated

Quality of Life in Patients With Statin-Associated Myopathy

Statin Adverse Reaction

United States
Hospital Universitario 12 de Octubre
Merck Sharp & Dohme LLC

Completed

Vytorin on Carotid Intima-media Thickness and Overall Rigidity (VYCTOR)

Cardiovascular Diseases
Organon and Co
Merck Shering-Plough JV Study

Completed

A Study to Assess the Cholesterol Lowering Effect of Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Elderly Patients With High Cholesterol at High or Moderately High Risk for Coronary Heart Disease (0653A-128)

Hypercholesterolemia
Mayo Clinic

Completed

Statin Interchange by Pharmacist Collaborative Practice Agreement (CPA)

Hypercholesterolemia

United States
Organon and Co

Completed

Ezetimibe/Simvastatin (10 mg/40 mg) vs. the Doubling of Atorvastatin in High Risk Participants (MK-0653A-134 AM1)(COMPLETED)

Hypercholesterolemia
Pfizer

Terminated

A Clinical Trial Comparing Torcetrapib/Atorvastatin to Ezetimibe/Simvastatin In Subjects With A Cholesterol Disorder.

Dyslipidemia | Hyperlipidemia

United States
Complexa, Inc.

Completed

A Study of the PK Interaction of CXA-10 With Pravastatin and Vytorin® in Healthy Males (DDI)

Acute Kidney Injury

United States
Organon and Co

Withdrawn

A Study to Evaluate the Efficacy and Safety of Vytorin Versus Standard Treatment of Other Statins in Moderate, Moderately High and High Risk Participants (MK-0653A-406) (VYCTORY)

Dyslipidemia
Brasilia Heart Study Group

Completed

Additive Effect of Ezetimibe Upon Simvastatin During Myocardial Infarction

Myocardial Infarction

Brazil
Organon and Co

Completed

MK0653A (Ezetimibe (+) Simvastatin) Compared to an Approved Drug (Atorvastatin) for the Treatment of High Cholesterol (0653A-051)(COMPLETED)

Hypercholesterolemia
Seoul National University Hospital
Merck Sharp & Dohme LLC

Unknown

Study to Compare the Effect of Vytorin (Simvastatin/Ezetimibe) 10/20mg Versus Atorvastatin 20mg on ApoB/ApoA1 Ratio in Subjects With Diabetes

Type 2 Diabetes Mellitus Without Insulin Treatment

Korea, Republic of
Organon and Co

Completed

EASEGO Study: Doubling of Atorvastatin/Simvastatin or INEGY in Patients With Hypercholesterolemia and Coronary Artery Disease(CAD)(0653A-089)

Atherosclerosis
Yonsei University

Recruiting

Effect of High-intensity Statin With Ezetimibe COmbination theRapy Versus High-intensity sTatin Monotherapy After Percutaneous Coronary Intervention With Drug-eluting Stents; the ESCORT Trial

Coronary Artery Disease Requiring Coronary Revascularization With Newer Generation DES Implantation

Korea, Republic of
Gachon University Gil Medical Center

Completed

Differential Metabolic Effects of Statins

Hypercholesterolemia

Korea, Republic of
Organon and Co

Completed

Ezetimibe Plus (+) Simvastatin Versus Atorvastatin Comparative Study (0653A-092)(COMPLETED)

Hypercholesterolemia
Organon and Co

Completed

A Multicenter, Randomized, Open Label Study to Evaluate the Lipid Lowering Efficacy and Safety of Vytorin® 10/20 vs. Atorvastatin 10mg in Hypercholesterolemia Patients With Metabolic Syndrome in Korea (0653A-129)(COMPLETED)

Hypercholesterolemia
Novartis Pharmaceuticals

Completed

Safety, Pharmacokinetics and Pharmacodynamics of LGT209 in Healthy Volunteers With Elevated Cholesterol and in Hypercholesterolemic Patients Treated With Statins

Hypercholesterolemia | LDL Cholesterol

United States
Organon and Co

Completed

A Study to Determine the Number of Patients Who Reach Optimal Cholesterol Levels on Each of Three Different Treatments (0653A-121)

Hypercholesterolemia
Organon and Co

Completed

Vytorin (10/20 Or 10/40) Compared to Atorvastatin (10 mg or 20 mg) in Patients With Coronary Artery Disease (0653A-126)(COMPLETED)

Hypercholesterolemia
Yonsei University

Unknown

Aspirin Mono Therapy 12-months After Drug-eluting Stents Implantation (statin)

Drug-eluting Stent (DES)

Korea, Republic of
Organon and Co

Completed

Ezetimibe (+) Simvastatin vs. Atorvastatin Comparative Study in DM or Metabolic Syndrome Patients (0653A-093)

Hypercholesterolemia
Baylor College of Medicine
Merck Sharp & Dohme LLC

Completed

Effects of Ezetimibe, Simvastatin, and Vytorin on Reducing L5 a Subfraction of LDL in Patients With Metabolic Syndrome. (Merck-123)

Metabolic Syndrome

United States
McMaster University
Canadian Cancer Society (CCS); Prostate Cancer Canada

Recruiting

A RAndomizeD Intervention for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients (RADICALPC)

Cardiovascular Disease | Prostate Cancer

United States, Canada, Australia, Brazil, Israel, Turkey, Colombia
Johns Hopkins University
National Institute on Aging (NIA)

Completed

High-Density Lipoprotein (HDL) Cholesterol Increased Plaque Stabilization in the Elderly (NIA-Plaque)

Cardiovascular Disease | Atherosclerosis

United States
Organon and Co

Completed

Cholesterol Lowering Level of MK0653A+Simvastatin in Patients With Hypercholesterolemia and Atherosclerotic or Coronary Vascular Disease (0653A-806)(COMPLETED)

Coronary Disease | Hypercholesterolemia | Atherosclerotic Disease
Fundación Lindavista del Corazón AC

Terminated

Left Ventricular Hypertrophy Reduction With Statins in Hypertensives Patients (MK0653A-168)

Hypertension
Medical College of Wisconsin

Completed

Effect of Diabetes Mellitus on Cholesterol Metabolism

Type 2 Diabetes Mellitus | Hypercholesterolemia | Type 1 Diabetes Mellitus

United States
Organon and Co

Completed

Eze/Simva Switch Study in Diabetics (0653A-807)

Diabetes Mellitus, Type 2
Organon and Co

Terminated

Vytorin Treating Uncontrolled Lipids (VyTUL) Study (0653A-122)

Cardiovascular Diseases | Diabetes Mellitus
Yonsei University

Completed

Early Effects of Intensive Lipid Lowering Treatment With Ezetimibe/ Simvastatin (Vytorin®) Assessed by Virtual Histology-Intravascular Ultrasound (VH-IVUS) and Optical Coherence Tomography (OCT) on Plaque Characteristics in Patients With Acute Coronary Syndrome

Acute Coronary Syndrome

Korea, Republic of
Organon and Co

Completed

A Multicenter Study to Evaluate the Cholesterol Lowering Effects of Two Marketed Products in Patients With Type 2 Diabetes Mellitus and Hypercholesterolemia (MK-0653A-077)

Type 2 Diabetes Mellitus | Hypercholesterolemia
Kuhnil Pharmaceutical Co., Ltd.

Completed

Efficacy and Safety of Prescription Omega-3 Fatty Acid Added to Stable Statin Therapy in Patients With Type 2 Diabetes and Hypertriglyceridemia

Diabetes Mellitus, Type 2 | Hypertriglycemia

Korea, Republic of
Hamamatsu University

Completed

Effects of Statins on the Pharmacokinetics for Midazolam in Healthy Volunteers (H-17-21)

Healthy Volunteers

Japan
Federal University of São Paulo

Completed

Effect of Simvastatin and Ezetimibe on Lipid and Inflammation

Inflammation | Hypercholesterolemia | Cardiovascular Risk | Prediabetes

Brazil
Organon and Co

Completed

A Study of SCH 58235 (Ezetimibe) When Added to Ongoing Therapy With a Statin in Participants With Primary Hypercholesterolemia, Known Coronary Heart Disease, or Multiple Cardiovascular Risk Factors (P02173)

Primary Hypercholesterolemia
Kowa Research Europe

Completed

Study to Compare the Efficacy and Safety of Pitavastatin and Simvastatin

Dyslipidemia | Hypercholesterolemia

Spain, Sweden, Denmark, Netherlands
Canadian Network for Observational Drug Effect...
Canadian Institutes of Health Research (CIHR); Drug Safety and Effectiveness...

Completed

High Potency Statins and Acute Kidney Injury

Hypercholesterolemia

Canada
Canadian Network for Observational Drug Effect...
Canadian Institutes of Health Research (CIHR); Drug Safety and Effectiveness...

Completed

High Potency Statins and the Risk of Diabetes (Statins-DM)

Cardiovascular Disease | Diabetes Mellitus, Type 2
Sunnybrook Health Sciences Centre
Merck Frosst Canada Ltd.; Schering-Plough

Terminated

INdians Followed for INtensive Lipid Lowering Treatment and Its safetY (INFINITY)

Hypercholesterolemia

Canada
Instituto de Investigación Hospital Universitario...
Instituto de Salud Carlos III

Not yet recruiting

Efficacy, Safety and Cost-efficacy of a Pre-emptive Genotyping Strategy in Patients Receiving Statins (PREVESTATGx)

Cardiovascular Diseases | Dyslipidemias | Statin Adverse Reaction | Pharmacogenic Myopathy

Spain
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Active, not recruiting

Investigating the Lowest Threshold of Vascular Benefits From LDL Cholesterol Lowering in Patients With Stable CV Disease (INTENSITY-HIGH)

Cardiovascular Diseases | Atherosclerosis

United Kingdom
Sanofi
Regeneron Pharmaceuticals

Completed

Evaluation of Alirocumab Versus Ezetimibe on Top of Statin in Asia in High Cardiovascular Risk Patients With Hypercholesterolemia (ODYSSEY EAST)

Hypercholesterolemia

China, India, Thailand
Sanofi
Regeneron Pharmaceuticals

Completed

Safety, Tolerability, and Effect of Alirocumab in High Cardiovascular Risk Patients With Severe Hypercholesterolemia Not Adequately Controlled With Conventional Lipid-modifying Therapies (ODYSSEY APPRISE)

Hypercholesterolemia

France, Belgium, Austria, Canada, Czechia, Denmark, Finland, Germany, Greece, Hungary, Poland, Romania, Slovakia, Slovenia, Spain, Switzerland
Organon and Co

Completed

Ezetimibe (SCH 58235) Taken With Either Atorvastatin or Simvastatin in Participants With Familial Hypercholesterolemia (MK-0653-018)

Familial Hypercholesterolemia

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