Search clinical trials for: Farnesyl Protein Transferase Inhibitor

Total 11026 results

Bristol-Myers Squibb

Completed

A Study to Evaluate the Long-term Safety and Efficacy of Deucravacitinib in Participants With Crohn's Disease or Ulcerative Colitis

Crohn Disease | Ulcerative Colitis

Romania, Italy, United States, Australia, Canada, China, Germany, Hungary, Japan, Netherlands, Poland, Portugal, Russian Federation, Spain, Taiwan, United Kingdom
Kadmon, a Sanofi Company

Terminated

Efficacy and Safety of Belumosudil in Subjects With Diffuse Cutaneous Systemic Sclerosis (dcSSC)

Diffuse Cutaneous Systemic Sclerosis

United States
Bristol-Myers Squibb

Completed

Continuing Treatment for Subjects Who Have Participated on a Prior Protocol Investigating Dasatinib

Multiple Indications Cancer

France, Poland
Chipscreen Biosciences, Ltd.
H & J CRO International, Inc.

Completed

Trial of Chiauranib Capsule on Pharmacokinetics to Assess the Effect of High Fat Diet in Healthy Volunteers

Healthy Volunteers

China
biotx.ai GmbH

Withdrawn

Phase II Safety Single-arm Study of CDK4/6 Inhibition With Palbociclib in Hospitalized, Moderate COVID-19 Cases to Prevent Thromboinflammation (CDK6COV)

COVID-19

Germany
Bo Hyun Kim

Enrolling by invitation

Efficacy and Safety of Sorafenib in Previously Treated Advanced Hepatocellular Carcinoma: SOPT Study

Advanced Hepatocellular Carcinoma

Korea, Republic of
Centre Leon Berard

Completed

Axitinib in1st Line Treatment for Patients With Advanced or Metastatic Papillary Renal Cell Carcinoma (AXIPAP)

Papillary Renal Cell Carcinoma

France
Pfizer

Completed

Study to IDEntify Patients With Advanced/Metastatic Non Small Cell Lung Cancer (NSCLC) and ALK and ROS1 Translocation and to Establish Their Therapeutic Management (IDEALK&ROS)

Non-Small Cell Lung Cancer

Spain
Fudan University

Completed

Prediction of 18F-FES-PET/CT Parameters on Palbociclib Combined With ET

Metastatic Breast Cancer

China
Bristol-Myers Squibb

No longer available

Expanded Access for Dasatinib
Jiangsu HengRui Medicine Co., Ltd.

Completed

Apatinib Dose Titration in Advanced or Metastatic Gastric Cancer

Gastric Cancer

China
AstraZeneca

Completed

Efficacy and Safety of Osimertinib for HK Chinese With Metastatic T790M Mutated NSCLC-real World Setting.

Non-small Cell Lung Cancer

China
Hangzhou ACEA Pharmaceutical Research Co., Ltd.
Guangdong Provincial People's Hospital; Acea Bio (Hangzhou) Co., Ltd.

Active, not recruiting

Safety, Pharmacokinetic and Preliminary Efficacy Study of AC0010 in Patients With EGFR T790M Positive NSCLC

Metastatic Non-small Cell Lung Cancer

China
Eisai Co., Ltd.

Completed

Pharmacokinetic Study of E7080/Lenvatinib in Chinese Patients With Unresectable Hepatocellular Carcinoma (HCC)

Unresectable Hepatocellular Carcinoma (HCC)

China
Massachusetts General Hospital
National Comprehensive Cancer Network

Unknown

Adjuvant Afatinib in Stage I-III NSCLC With EGFR Mutation

Non Small Cell Lung Cancer

United States
Memorial Sloan Kettering Cancer Center
Novartis; National Comprehensive Cancer Network

Completed

Adjuvant Dabrafenib (GSK2118436) in Patients With Surgically Resected AJCC Stage IIIC Melanoma Characterized by a BRAFV600E/K Mutation

Melanoma

United States
Boehringer Ingelheim

Completed

GIOTRIF in First Line Therapy of Advanced NSCLC With EGFR-mutations

Carcinoma, Non-Small-Cell Lung

Germany
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Unknown

Effect and Safety of Apatinib on Radiation-Induced Brain Injury

Radiation Injuries

China
University of Texas Southwestern Medical Center
Novartis

Withdrawn

Ceritinib in Mutation and Oncogene Directed Therapy in Thyroid Cancer

Metastatic Anaplastic Thyroid Cancer | Locally Advanced Anaplastic, Undifferentiated Thyroid Cancer

United States
Norman B. Gaylis, MD

Completed

An Evaluation of the Optimal Dose of Tofacitinib Needed to Achieve Low Disease Activity (LDA) or Clinical Remission in Patients With Active Rheumatoid Arthritis (RA) as Measured From a Clinical and Structural Perspective

Rheumatoid Arthritis

United States
University Health Network, Toronto

Completed

A Study of Radiation With Sorafenib in Advanced Cancer

Cancer

Canada
Hangzhou ACEA Pharmaceutical Research Co., Ltd.

Completed

Preliminary Evaluation of Safety and Efficacy by [14C] AC0010 Trail and Subsequent AC0010 Treatment

Carcinoma，Non-Small-Cell Lung

China
Boehringer Ingelheim

Approved for marketing

Expanded Access Study of Afatinib in Treatment-naive or Chemotherapy Pre-treated Patients With Non-small Cell Lung Cancer (NSCLC)

Carcinoma, Non-Small-Cell Lung

Korea, Republic of
Xuzhou Central Hospital

Unknown

Apatinib for Advanced Lung Squmamous Carcinoma

Lung Squamous Cell Carcinoma
Cancer Research UK

Terminated

A Phase I Study of AZD0424 Alone and in Combination in Advanced Solid Tumours (AZD0424)

Advanced Solid Tumours

United Kingdom
Hebei Medical University Fourth Hospital

Unknown

Prospective, Multicenter, Observational Study of Apatinib Single or Combined Capecitabine for Treatment of Patients With Metastatic Her-2 Negative Breast Cancer

Breast Cancer Metastatic

China
Massachusetts General Hospital
Bristol-Myers Squibb; Dana-Farber Cancer Institute; Brigham and Women's Hospital

Completed

Dasatinib in Relapsed Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

United States
Anhui Provincial Hospital

Unknown

Research On the Optimized Treatment Method For Apatinib's Cure Of Advanced Gastric Cancer

Two Different Treatment Methods

China
Boehringer Ingelheim

Terminated

Afatinib in EGFR+NSCLC (Recurrent or Stage IV) - Patients With Poor Performance Status (ECOG 2 or 3)

Carcinoma, Non-Small-Cell Lung | ErbB Receptors

United States
Groupe Hospitalier Paris Saint Joseph

Withdrawn

Phase II Study of Afatinib as Third- or Further-line Treatment for Patients With Stage IV Bronchial Adenocarcinoma, Harboring Wild-type EGFR, Expressing the Neurotensin - Neurotensin Receptor Complex (THEN)

SMALL CELL LUNG CARCINOMA

France
Jean M. Tersak, M.D.
Pfizer

No longer available

Treatment With Crizotinib Single Patient Expanded Access IND 134375

Inflammatory Myofibroblastic Tumour
Shanghai Zhongshan Hospital

Unknown

Adjuvant Therapy With Apatinib for HCC Patients With PVTT Who Underwent Radical Resection

Carcinoma, Hepatocellular

China
Pfizer

Terminated

A Long Term Study To Evaluate The Safety And Tolerability Of CP-690,550 For Patients With Moderate To Severe Chronic Plaque Psoriasis

Psoriasis

United States, Spain, Korea, Republic of, Taiwan, Canada, Poland, Belgium, Denmark, Germany, Serbia, United Kingdom, France, Czechia, Hungary, Mexico, Colombia, Russian Federation, Croatia, Singapore, Australia, Austria, Slovakia, S... and more
OncoTherapy Science, Inc.

Completed

Phase 1 Study of OTS167 in Patients With Solid Tumors

Solid Tumors | Metastatic Tumors

United States
Junling Li

Unknown

The Efficacy and Safety of Apatinib Monotherapy in Maintenance Treatment of Extensive-stage Small-cell Lung Cancer

Apatinib in Maintenance Treatment

China
Yale University

Completed

Tofacitnib for the Treatment of Alopecia Areata and Variants

Alopecia Areata (AA) | Alopecia Totalis (AT) | Alopecia Universalis (AU)

United States
Samsung Medical Center

Completed

Safety and Clinical Activity of Lapatinib in Patients With HER2-positive Refractory Advanced Cancer

HER2-positive Refractory Advanced Cancer

Korea, Republic of
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Terminated

Ponatinib for Advanced Medullary Thyroid Cancer

Thyroid Neoplasms

United States
Hangzhou Cancer Hospital

Unknown

Apatinib for Metastatic Esophageal Cancer.

Esophageal Cancer | Apatinib | Metastatic Esophageal Cancer

China
Peking University Cancer Hospital & Institute
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Study of Second-line Treatment With Apatinib After TACE in Advanced Hepatocellular Carcinoma Patients

Hepatocellular Carcinoma

China
Huashan Hospital

Unknown

Targeted Therapy With Gefitinib in Patients With USP8-mutated Cushing's Disease

Cushing's Disease | Corticotrophin Adenoma

China
Pfizer

Completed

Investigation Of The Metabolism, And Excretion Of [14c]-PF-05212384 In Healthy Male Volunteers

Healthy

United Kingdom
Pfizer

Withdrawn

A Clinical Study Testing The Safety And Efficacy Of Crizotinib In East Asian Patients With Anaplastic Lymphoma Kinase (ALK) Positive Advanced Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer
Pfizer

Completed

Pharmacokinetics Of CP-690,550 In Patients With Impaired Renal Function

Renal Impairment

United States
University of Turin, Italy

Unknown

Perspective Evaluation of Hormones Involved in Serum Phosphate Homeostasis in Patients With Metastatic Renal Cells Carcinoma or Hepatocellular Carcinoma Treated With Sorafenib (SORHORM) (SORHORM)

Kidney Cancer | Liver Cancer

Italy
King's College London
Bayer

Unknown

Sorafenib in Previously Treated Malignant Mesothelioma (SMS)

Mesothelioma

United Kingdom
AstraZeneca
Cancer International Research Group (CIRG)

Completed

Ph II Early BC Pre-Surgical Biologic Study

Breast Cancer
AstraZeneca

Completed

Gefitinib in the Treatment of the First Relapse of Prostate Cancer Beyond Prostatectomy or Radiotherapy

Prostate Cancer

Finland
AstraZeneca

Completed

A Study of IRESSA in Relapsed and Refractory Small Cell Lung Cancer

Small Cell Lung Cancer

United Kingdom, Denmark
M.D. Anderson Cancer Center

Recruiting

Pembrolizumab and Lenvatinib for the Treatment of Serous Ovarian Cancer Patients

Recurrent Primary Peritoneal High Grade Serous Adenocarcinoma | High Grade Ovarian Serous Adenocarcinoma | Recurrent High Grade Fallopian Tube Serous Adenocarcinoma | Recurrent High Grade Ovarian Serous Adenocarcinoma | High Grade Fallopian Tube Serous Adenocarcinoma | Peritoneal High Grade...

United States

Search clinical trials for: Farnesyl Protein Transferase Inhibitor

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