Search clinical trials for: Freund's Adjuvant

Total 8266 results

Novavax
Bill and Melinda Gates Foundation

Completed

A Study to Determine the Safety and Efficacy of the RSV F Vaccine to Protect Infants Via Maternal Immunization

Respiratory Syncytial Virus Infections

United States, Argentina, Australia, Bangladesh, Chile, Mexico, New Zealand, Philippines, South Africa, Spain, United Kingdom
PepTcell Limited

Completed

Influenza Vaccine Challenge Study in Healthy Subjects

Influenza

United Kingdom
European Organisation for Research and Treatment...

Completed

BCG With or Without Mitomycin in Treating Patients With Bladder Cancer

Bladder Cancer

Netherlands, Belgium, United Kingdom, Italy, Portugal, Turkey
Guangxi Medical University

Not yet recruiting

Adjuvant Tislelizumab Plus Lenvatinib for Patients at High-risk of HCC Recurrence After Curative Resection or Ablation (PREVENT-2)

Recurrence | Hepatocellular Carcinoma | Immune Checkpoint Inhibitor

China
GlaxoSmithKline

Completed

Evaluation of Immunogenicity, Reactogenicity and Safety of Herpes Simplex (gD) Candidate Vaccine With/Without Adjuvant

Prophylaxis Herpes Simplex

Belgium
National Cancer Institute (NCI)

Recruiting

Phase I/II Evaluation of a Cancer Lysate Vaccine and Montanide(R) ISA-51 VG With Entinostat and Nivolumab as Adjuvant Therapy Following Chemoradiation Therapy With or Without Surgery for Locally Advanced Esophageal Cancer

Neoplasms | Esophageal Neoplasms | Esophagus Cancer | Esophagus Neoplasm | Neoplasms, Esophageal | Esophageal Cancer (EsC)

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Shenzhen Sixth People's Hospital; Zhongshan People's Hospital, Guangdong, China

Recruiting

Tislelizumab Combined With Chemotherapy Followed by Surgery Versus Up-front Surgery in Resectable Head and Neck Squamous Cell Carcinoma (REDUCTION-I)

Head and Neck Squamous Cell Carcinomas

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Tislelizumab Combined With Chemotherapy Followed by Surgery Versus Up-front Surgery in Resectable Clinically Node-negative Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma

China
Clover Biopharmaceuticals AUS Pty Ltd
International Vaccine Institute; Coalition for Epidemic Preparedness Innovations

Completed

A Controlled Phase 2/3 Study of Adjuvanted Recombinant SARS-CoV-2 Trimeric S-protein Vaccine (SCB-2019) for the Prevention of COVID-19 (SCB-2019)

COVID-19

Colombia, Belgium, Brazil, Philippines, South Africa
Ludwig Institute for Cancer Research
Institute of Cancer Research, United Kingdom

Completed

Study of NY-ESO-1 ISCOMATRIX® in Patients With High-risk, Resected Melanoma

Melanoma

United Kingdom, Australia, New Zealand
National Institute of Allergy and Infectious Diseases...

Completed

H5N8 Mix and Match With or Without AS03 or MF59 in Healthy Adults: Immunology

Avian Influenza

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Immunotoxin Therapy Before and After Surgery in Treating Patients With Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
Severance Hospital

Unknown

A Phase III Trial of Carboplatin as Adjuvant Chemotherapy in Triple Negative Breast Cancer

Breast Cancer
Seqirus

Completed

Clinical Study to Evaluate Safety, Immunogenicity of Investigational Flu Vaccine Compared to an Approved Flu Vaccine in Children Previously Vaccinated in Trial V118_05 (NCT01964989)

Influenza

Finland, Philippines, Thailand
Novartis
Novartis Vaccines

Completed

A Dose Ranging Study Comparing Different Combinations of Adjuvanted and Non-adjuvanted Influenza Vaccines in Healthy Children 6 to <36 Months of Age

Influenza

Belgium
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Intraperitoneal Chemotherapy Guided by the Detection of DNA in Peritoneal Lavage Fluid in Patients With Gastric Cancer

Gastric Cancer

China
Lei Li

Recruiting

Prognosis of Low-grade Endometrial Stromal Sarcoma

Recurrence | Survival Outcomes | Adjuvant Therapy | Hormone Therapy | Low Grade Endometrial Stromal Sarcoma of Uterus (Diagnosis) | Fertility-sparing Surgery | Fertility Outcomes

China
Agenus Inc.

Completed

Phase 1a Study to Evaluate Immunogenicity of ASV®

Solid Tumor, Adult

United States
National Institute of Allergy and Infectious Diseases...

Completed

H5N8 Mix and Match With or Without AS03 or MF59 in Healthy Adults

Influenza | Avian Influenza

United States
U.S. Army Medical Research and Development Command
GlaxoSmithKline; Walter Reed Army Institute of Research (WRAIR); The PATH Malaria...

Completed

Phase I/II Trial of a Malaria Vaccine in Adults Living in the United States of America

Malaria | Plasmodium Falciparum Malaria

United States
Centro Oncologico de Excelencia

Unknown

Immunotherapy After Surgery in Treating Patients With Breast Cancer, Colon Cancer, or Melanoma

Breast Cancer | Colorectal Cancer | Melanoma (Skin)

Argentina
Robert Pass, MD
National Institute of Allergy and Infectious Diseases (NIAID); MCM Vaccines...

Completed

Recombinant CMV gB Vaccine in Postpartum Women

Cytomegalovirus Infections

United States
Eye & ENT Hospital of Fudan University
Peking University Third Hospital; Zhongshan Ophthalmic Center, Sun Yat-sen... and other collaborators

Recruiting

Neoadjuvant Radiotherapy for Malignant Lacrimal Sac Tumors

Malignant Tumor of Lacrimal Drainage Structure

China
Icahn School of Medicine at Mount Sinai

Terminated

CivaSheet With Radical Prostatectomy & Adjuvant External Beam Radiation

Prostate Cancer

United States
Seoul National University Hospital

Completed

Locoregional Recurrence After Neoadjuvant Versus Adjuvant Chemotherapy

Breast Cancer

Korea, Republic of
Al-Azhar University

Active, not recruiting

Sclerotherapy and Bone Marrow Injection In Aneurysmal Bone Cyst

Orthopedic Disorder

Egypt
U.S. Army Medical Research and Development Command
GlaxoSmithKline; Walter Reed Army Institute of Research (WRAIR); The PATH Malaria...

Completed

Phase I/II Trial of a Malaria Vaccine in Adults Living in the United States of America

Plasmodium Falciparum Malaria

United States
Eli Lilly and Company

Completed

A Study in Participants With Advanced Solid Tumors

Solid Tumor

China
Fudan University

Completed

Oxaliplatine Based Adjuvant Chemotherapy for Stage II/III Colorectal Cancer: 8 Cycles Versus 12 Cycles

Colorectal Cancer

China
Sanofi Pasteur, a Sanofi Company

Completed

Study of Recombinant Influenza Vaccine Containing Different H3 Antigens Without or With Adjuvant in Healthy Adult Subjects (FBP00004)

Healthy Volunteers | Influenza Immunisation

United States
West Virginia University

Recruiting

The Role of Sugammadex in Posotoperative Urinary Retention in Patients Undergoing Pelvic Floor Reconstructive Procedures

Postoperative Urinary Retention

United States
Istituto Oncologico Veneto IRCCS

Recruiting

Pure Florid and Pleomorphic Lobular Carcinoma in Situ of the Breast: Towards an Increasingly Uniform Management

Pleomorphic Lobular Breast Carcinoma in Situ | Breast Florid Lobular Carcinoma in Situ

Italy
Janssen Vaccines & Prevention B.V.

Completed

A Safety, Tolerability and Immunogenicity Study of 2 Different Regimens of Tetravalent Ad26.Mos4.HIV Prime Followed by Boost With Tetravalent Ad26.Mos4.HIV Along With Either Clade C gp140 Plus Adjuvant OR With a Combination of Mosaic and Clade C gp140 Plus Adjuvant in Healthy HIV Uninfected Adults (IPCAVD-012)

Healthy

United States, Rwanda, Kenya
Zhejiang University

Recruiting

Transarterial Neoadjuvant Chemotherapy vs.Traditional Intravenous Chemotherapy For Locally Advanced Gastric Cancer With SOX+PD-1 (TACTIC)

Locally Advanced Gastric Carcinoma

China
Onyvax

Unknown

Monoclonal Antibody Therapy and/or Vaccine Therapy in Treating Patients With Locally Advanced or Metastatic Colorectal Cancer

Colorectal Cancer

United Kingdom
PepTcell Limited
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Efficacy of FLU-v in an H1N1 Influenza Human Challenge Model

Influenza

United Kingdom
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Shanghai Public Health Clinical Center; Beijing Simoonrecord Pharmaceutical...

Completed

A Phase ⅠStudy of the Recombinant Mycobacterium Tuberculosis Vaccine Freeze-dried (AEC/BC02)

Tuberculosis

China
GlaxoSmithKline

Active, not recruiting

Safety, Immunogenicity and Efficacy of GSK S. Aureus Candidate Vaccine (GSK3878858A) When Administered to Healthy Adults (Dose-escalation) and to Adults 18 to 64 Years of Age With a Recent S. Aureus Skin and Soft Tissue Infection (SSTI)

Infections, Soft Tissue

United States, South Africa, Australia, India, New Zealand, United Kingdom, Poland
Region Skane

Completed

Cerebral Changes Following CTS Treated With Guided Plasticity

Carpal Tunnel Syndrome
Institut Curie
Servier; UNICANCER

Completed

Comparison Between Fotemustin to Intensive Surveillance in Patients With High Risk Uveal Melanoma (FOTEADJ)

Uveal Melanoma

France, Switzerland
Massachusetts General Hospital

Recruiting

Culturally Aware AET Non-Initiation Intervention

Breast Cancer | Treatment Adherence | Survivorship | Treatment Refusal | Treatment Compliance

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Clinical Trial in Healthy, HIV-1-Uninfected Adult Participants to Compare the Safety, Tolerability and Immunogenicity of CH505TF gp120 Produced From Stably Transfected Cells to CH505TF gp120 Produced From Transiently Transfected Cells

HIV Infections

United States
Sun Yat-sen University
Zhejiang Cancer Hospital; Fudan University; Tianjin Medical University Cancer... and other collaborators

Unknown

Phase III Study of Neo-adjuvant Chemoradiotherapy Followed by Surgery for Squamous Cell Esophageal Cancer

Squamous Cell Esophageal Carcinoma

China
Novavax
Department of Health and Human Services

Completed

A/H5N1 Virus-Like Particle Antigen Dose Ranging Study With Adjuvant 1

Influenza (Pandemic)

United States
Myrexis Inc.

Unknown

R-Flurbiprofen in Treating Patients With Localized Prostate Cancer at Risk of Recurrence

Prostate Cancer

United States
Tehran University of Medical Sciences

Completed

Safety Assessment of a Multipeptide-gene Vaccine in CML

Leukemia, Myeloid, Chronic

Iran, Islamic Republic of
BioTech Tools S.A.

Completed

Clinical Safety and Tolerability Study of gpASIT+TM and gpASIT+TM/Immunoregulating Adjuvant to Treat Seasonal Grass Pollen Rhinoconjunctivitis

Seasonal Allergic Rhinoconjunctivitis

Belgium
ETOP IBCSG Partners Foundation
AstraZeneca AG Switzerland

Not yet recruiting

A Study to Evaluate the Benefit of Adding Durvalumab After Chemotherapy, Durvalumab and Surgery in Patients With Early-stage, Operable, Non-small Cell Lung Cancer. (ADOPT-lung)

Non Small Cell Lung Cancer
Sir Run Run Shaw Hospital
Hangzhou Neoantigen Therapeutics Co., Ltd.

Recruiting

Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Subjects With Resected Digestive System Neoplasms

Digestive System Neoplasms

China
Lars Olaf Cardell

Completed

Is Intralymphatic Allergen Immunotherapy Effective and Safe?

Allergic Rhinitis Due to Grass Pollen

Sweden

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