Search clinical trials for: Glucagon-only bionic pancreas - placebo

Total 380 results

University Hospital, Gentofte, Copenhagen
Eli Lilly and Company

Enrolling by invitation

Delineation of the Diabetogenic Role of Extrapancreatic Glucagon in Totally Pancreatectomised Patients Using Glucagon Receptor Antagonism (PX-GRA)

Diabetes After Total Pancreatectomy
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Efficacy and Tolerability of Pancrelipase Microtablet (MT) Capsules for the Treatment of Cystic Fibrosis-dependent Exocrine Pancreatic Insufficiency

Malabsorption Syndromes | Cystic Fibrosis | Steatorrhea | Exocrine Pancreatic Insufficiency

United States, Canada
University of Aarhus

Completed

GLP-1 Infusion and Long-Time Fasting

Type 2 Diabetes

Denmark
Tel Aviv University

Completed

Attention Bias Modification Treatment (ABMT) for Anxiety Disorders in Youth

Anxiety Disorders

Israel
Chen Wei Ren, MD

Unknown

Effects of Glucagon Like Peptide-1 on No-reflow

Acute ST-segment Elevation Myocardial Infarction

China
Ionis Pharmaceuticals, Inc.

Completed

A Safety andTolerability Study of Multiple Doses of ISIS-DMPKRx in Adults With Myotonic Dystrophy Type 1

Myotonic Dystrophy Type 1

United States
Smith, Timothy R., M.D.
Ionis Pharmaceuticals, Inc.; Clinvest Research, LLC

Completed

Efficacy and Safety of IONIS-PKKRx for Preventive Treatment of Chronic Migraine

Chronic Migraine

United States
AdventHealth Translational Research Institute

Active, not recruiting

Effect of Prolonged (72 Hour) Glucagon Administration on Energy Expenditure in Healthy Obese Subjects (GIO B)

Obesity

United States
Eli Lilly and Company

Completed

Effect of LY2189265 on Insulin Secretion in Response to Intravenous Glucose

Diabetes Mellitus, Type 2

Germany
Sciwind Biosciences APAC CO Pty. Ltd.
Hangzhou Sciwind Biosciences Co., Ltd.

Completed

To Evaluate the Safety, Tolerability, PK, and PD of XW003 Injection in Healthy Adult Participants (XW003)

Obesity | Type 2 Diabetes Mellitus | Nonalcoholic Steatohepatitis

Australia
University of Copenhagen
Hvidovre University Hospital

Completed

Investigation of GLP-2 Mechanism of Action (GA-8)

Healthy

Denmark
Mayo Clinic
National Center for Research Resources (NCRR); Rose Pharma A/S

Completed

Effects of ROSE-010 on GI Transit in Constipation Predominant Irritable Bowel Syndrome (C-IBS) Patients

Irritable Bowel Syndrome Constipation Predominant

United States
Legacy Health System
Juvenile Diabetes Research Foundation; Oregon Health and Science University

Completed

Sensor-Augmented Insulin Delivery: Insulin Plus Glucagon Versus Insulin Alone

Type 1 Diabetes

United States
University of Maryland, Baltimore

Recruiting

Glucagon-like Peptide-1 in Type 1 Diabetes

Type1 Diabetes Mellitus

United States
Asan Medical Center
Samsung Medical Center; Seoul National University Hospital; Seoul National University... and other collaborators

Recruiting

Albumin and Crystalloid Administration in Septic Shock (ALCAMIST)

Septic Shock

Korea, Republic of
OliPass Corporation
Novotech (Australia) Pty Limited

Completed

Study of OLP-1002 Injections for Reducing Moderate to Severe Pain Due to Osteoarthritis in Hip and/or Knee Joint

Osteoarthritis

Australia
Pfizer

Terminated

Voxelotor Neurocognitive Function Study

Sickle Cell Disease

United States
University of Copenhagen
Hvidovre University Hospital

Completed

Effects of Gut Peptides on Bone Remodeling (KS-3)

Healthy

Denmark
Ionis Pharmaceuticals, Inc.

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of IONIS FXI-LRx in up to 84 Healthy Volunteers

Healthy Participants

Canada
Ionis Pharmaceuticals, Inc.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Ionis AGT-LRx in Healthy Volunteers

Healthy Volunteers

Canada
University of Maryland, Baltimore

Active, not recruiting

GLP-1 and Hypoglycemia

Type 2 Diabetes Mellitus

United States
NovoBliss Research Pvt Ltd
Orgenetics, Inc.

Recruiting

A Clinical Study to Assess the Safety and Effectiveness of Plant-based Biotin and Plant Based Biotin With Silica in Healthy Human Subjects With Complaints of Hair Fall, Thin, Dry, & Brittle Hair, and Dry Skin

Dry Skin | Dry Hair | Hair Falling | Thin Hair | Brittle Hair

India
University of Florida
Lallemand Bio-Ingredients

Terminated

Beta-glucan and Fatigue in HSCT Survivors

Autologous Haemopoietic Stem Cell Transplant

United States
Kemin Foods LC
KGK Science Inc.

Completed

Ability of Beta-glucan Supplementation to Augment Immune Function

Stress | Flu | Cold | Flu Symptom | Cold Symptom | Gastrointestinal Tolerance | Supplement

Canada
Bionov
Seppic

Completed

Multicentre, Double-blind Study Versus Placebo on Impact and Safety of Extramel® 140 IU on Perceived Stress, Physical and Intellectual Fatigue, Pain Perception if Present, and the Impact on the Quality of Life (Ex Stress II)

Quality of Life | Pain | Fatigue | Life Stress
Shulov Innovate for Science Ltd. 2012

Recruiting

Safety, Tolerability and Efficacy of ZEP-3Na (0.1% or 1%) Compared to Placebo in Subjects With Mild to Moderate Atopic Dermatitis

Atopic Dermatitis

Israel
Xigo Health LLC

Completed

Safety and Efficacy Study of Oral XIGO Tablets to Treat The Common Cold

Common Cold

United States
MedDay Pharmaceuticals SA

Completed

Effect of MD1003 in Amyotrophic Lateral Sclerosis (MD1003-ALS)

Motor Neuron Disease | Amyotrophic Lateral Sclerosis | ALS

France
The Hong Kong Polytechnic University
Prince of Wales Hospital, Shatin, Hong Kong

Recruiting

Warmth and Transcutaneous Electrical Nerve Stimulation (TENS) in Improving Cognitive Functions in People With Dementia

Dementia

Hong Kong
Ionis Pharmaceuticals, Inc.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS-MAPTRx in Patients With Mild Alzheimer's Disease

Mild Alzheimer's Disease

United Kingdom, Netherlands, Germany, Sweden, Canada, Finland
Ionis Pharmaceuticals, Inc.

Completed

Safety, Tolerability, and Efficacy of IONIS-GHR-LRx in Participants With Acromegaly Being Treated With Long-acting Somatostatin Receptor Ligands

Acromegaly

United States, Hungary, Serbia, Romania, Russian Federation, Lithuania, Poland
University of Copenhagen
Hvidovre University Hospital

Completed

Gut Hormones and Bone Remodeling in Humans (KS-2) (KS-2)

Healthy

Denmark
Mikkel Christensen

Completed

Glucose-Dependent Insulinotropic Polypeptide - Effects on Markers of Bone Turnover in Patients With Type 1 Diabetes

Type 1 Diabetes Mellitus
Integrative Medicine Institute
Beth Israel Medical Center; Southwest College of Naturopathic Medicine; Women... and other collaborators

Completed

Zinc for the Treatment of Herpes Simplex Labialis (HSL)

Herpes Simplex Labialis

United States
Probi AB
Lund University

Completed

Probiotics Against Low Grade Inflammation and Increased Intestinal Permeability in the Elderly

Low-grade Inflammation | Increased Intestinal Permeability

Sweden
Gelesis, Inc.
inVentiv Health Clinical

Completed

Gelesis Glycemic Index Study (GLIDE)

Obesity | Diabetes | PreDiabetes

Canada
Huazhong University of Science and Technology

Unknown

The Effect of Insoluble Yeast Beta-glucan Intake on Pre-diabetic Patients

Pre-diabetic

China
National Institute of Allergy and Infectious Diseases...

Completed

Quadrivalent HPV Vaccine to Prevent Anal HPV in HIV-infected Men and Women

HIV Infections

United States, Puerto Rico, Brazil
Ionis Pharmaceuticals, Inc.
Akcea Therapeutics

Completed

The APPROACH Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Patients With Familial Chylomicronemia Syndrome

Familial Chylomicronemia Syndrome

United States, Brazil, Canada, France, Germany, Hungary, Israel, Italy, Netherlands, South Africa, Spain, United Kingdom
Government Dental College and Research Institute...

Completed

Clinical Efficacy of 0.75% Boric Acid Gel in Chronic Periodontitis

Chronic Periodontitis

India
Case Western Reserve University
Medical University of South Carolina; National Institute of Diabetes and Digestive...

Active, not recruiting

Effects of Semaglutide in HIV-Associated Lipohypertrophy

Obesity | HIV/AIDS | Lipohypertrophy

United States
Sciwind Biosciences APAC CO Pty. Ltd.
Hangzhou Sciwind Biosciences Co., Ltd.; Sciwind Biosciences USA Co., Ltd.

Recruiting

XW004 To Evaluate the Safety, Tolerability, PK, and PD of Oral Ecnoglutide Tablet in Healthy Adults

Obesity | Type 2 Diabetes Mellitus

Australia
Nutrition 21, Inc.
ALS Beauty and Personal Care

Recruiting

Effectiveness of a Novel Dietary Ingredient on Hair Growth and Skin's Appearance

Hair Thinning | Facial Skin Texture | Skin Ageing

United States
Akcea Therapeutics
Ionis Pharmaceuticals, Inc.

Terminated

The BROADEN Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familial Partial Lipodystrophy

Familial Partial Lipodystrophy

United States, Netherlands, Belgium, Brazil, Canada, Germany, Russian Federation
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-809 Alone and in Combination With VX-770 in Cystic Fibrosis (CF) Patients Homozygous or Heterozygous for the F508del-CFTR Mutation

Cystic Fibrosis

United States, France, United Kingdom, Germany, Australia, New Zealand, Belgium
University Hospital, Gentofte, Copenhagen

Completed

The Effect of GIP and GLP-1 on Insulin and Glucagon Secretion in Patients With HNF1A-diabetes Treated With or Without Sulphonylurea (HNF1A-Clamp)

Maturity-Onset Diabetes of the Young, Type 3

Denmark
GlyPharma Therapeutics
VectivBio AG

Completed

Safety, Efficacy, PD of FE203799 in Short Bowel Syndrome on Parenteral Support

Short Bowel Syndrome

Denmark
PepTcell Limited

Completed

Influenza Vaccine Challenge Study in Healthy Subjects

Influenza

United Kingdom
University Hospital Rijeka
Institute AllergoSan

Recruiting

The Effect of a Probiotic Mixture in Obese Patients With Irritable Bowel Syndrome

Obesity | IBS - Irritable Bowel Syndrome

Croatia
Ionis Pharmaceuticals, Inc.

Active, not recruiting

CARDIO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Participants With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)

Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)

United States, Australia, Spain, Canada, Germany, Japan, Italy, Israel, Argentina, France, Portugal, Austria, Brazil, Greece, United Kingdom, Czechia, Sweden, Belgium, Denmark, Poland, Puerto Rico

Search clinical trials for: Glucagon-only bionic pancreas - placebo

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