Search clinical trials for: HIV Protease Inhibitors

Total 69636 results

ViiV Healthcare
Pfizer

Terminated

Pharmacokinetic Interaction Between Maraviroc And Fosamprenavir/Ritonavir In Healthy Subjects

Healthy

Singapore
Mayo Clinic

Withdrawn

Lopinavir and Ritonavir in Improving Immune Response to Vaccines in Patients With Complete Remission Following A Bone Marrow Transplant for Hodgkin Lymphoma

Hodgkin Lymphoma | Stage III Adult Hodgkin Lymphoma | Stage IV Adult Hodgkin Lymphoma | Stage I Adult Hodgkin Lymphoma | Stage II Adult Hodgkin Lymphoma

United States
The HIV Netherlands Australia Thailand Research...
Chulalongkorn University; Bamrasnaradura Infectious Diseases Institute

Completed

Pharmacokinetics and Safety of Rifabutin 150 mg Once Daily Versus Rifabutin 300 mg Thrice Weekly

HIV | Tuberculosis

Thailand
Boehringer Ingelheim

Completed

Investigation of Ritonavir Effects on Afatinib Exposure in Healthy Subjects

Healthy

Germany
National Institute of Allergy and Infectious Diseases...

Completed

The Effectiveness of Ritonavir Plus Zidovudine Plus Lamivudine in HIV-Infected Patients

HIV Infections

United States
The Rogosin Institute
Weill Medical College of Cornell University

Withdrawn

Velcade for Proliferative Lupus Nephritis

Proteinuria | Lupus Nephritis | Hematuria

United States
Centre Hospitalier Universitaire Vaudois

Completed

Drug-drug Interactions Between Antiretroviral Drugs and Cardiovascular Drugs in Elderly Patients

Cardiovascular Diseases | HIV Infections | Drug Interactions

Switzerland
University of Iowa
Holden Comprehensive Cancer Center

Terminated

Evaluation of Nelfinavir and Chemoradiation for Pancreatic Cancer

Pancreatic Neoplasms
Chinese University of Hong Kong

Completed

Safety and Clinical and Virologic Outcomes in CKD Patients Treated With Nirmatrelvir-ritonavir

COVID-19 | Chronic Kidney Disease stage4 | Chronc Kidney Disease Stage 5

Hong Kong
Pfizer

Completed

A Study to Learn About the Study Medicines (Nirmatrelvir Plus Ritonavir) in People Aged 12 Years or Older With COVID-19 and a Compromised Immune System

COVID-19

Spain, United States, Australia, Canada, Bulgaria, Slovakia, Mexico, Hungary, Brazil
Obafemi Awolowo University
University of Liverpool

Completed

Pharmacokinetic Interaction Between Nitazoxanide and Atazanavir/Ritonavir in Healthy Volunteers

Drug Interaction

Nigeria
National Institute of Allergy and Infectious Diseases...

Completed

A Study of 141W94 Used Alone or in Combination With Zidovudine Plus 3TC in HIV-Infected Patients

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Randomized Trial of the Efficacy and Safety of a Strategy of Starting With Nelfinavir Versus Ritonavir Added to Background Antiretroviral (AR) Nucleoside Therapy in HIV-Infected Individuals With CD4+ Cell Counts Less Than or Equal to 200/mm3

HIV Infections

United States, Canada
Hospital of Prato

Unknown

Baricitinib in Symptomatic Patients Infected by COVID-19: an Open-label, Pilot Study. (BARI-COVID)

Pharmacological Action

Italy
Shanghai Public Health Clinical Center

Unknown

Efficacy and Safety of Darunavir and Cobicistat for Treatment of COVID-19 (DC-COVID-19)

Coronavirus | Pneumonia, Pneumocystis

China
American Research Corporation
AbbVie

Completed

A Study to Investigate HCV Response Rates in Real World Patients: HEARTLAND Study (HEARTLAND)

Chronic Hepatitis C
Willem Daniel Francois Venter
Medical Research Council, South Africa

Completed

Evaluation of Low-dose Darunavir in a Switch Study (DRV)

HIV Infections

South Africa
Hepa C

Completed

Effectiveness, Safety and Clinical Outcomes of Paritaprevir/Ombitasvir/r+Dasabuvir 8 Weeks (3D8)

Hepatitis C Infection

Spain
GlaxoSmithKline

Completed

Drug Interaction Study Between Eltrombopag and Lopinavir/Ritonavir in Healthy Adult Subjects.

Hepatitis C

United States
Indiana University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of the HIV Protease Inhibitors Atazanavir and Lopinavir/Ritonavir on Cardiovascular Disease Risk Factors

Endothelial Dysfunction

United States
University of Modena and Reggio Emilia

Unknown

Efficacy Study to Evaluate the Effect of New Antiviral Drugs on HCV Infection.

Chronic Hepatitis, C Virus

Italy
Catholic University of the Sacred Heart

Completed

Atazanavir and Lamivudine for Treatment Simplification (AtLaS)

HIV Infections

Italy
Phoenix Children's Hospital
Abbott

Completed

Comparison of Liquid Kaletra and Low Dose Kaletra Tablets

HIV Infections

United States
Germans Trias i Pujol Hospital

Completed

Clinical Study to Evaluate the Efficacy and Safety of Lopinavir/Ritonavir Monotherapy Versus Darunavir/Ritonavir Monotherapies as Simplification Switching Strategies of PI/NNRTI-Triple Therapy Based-Regimens

HIV Infections

Spain
National Institute of Allergy and Infectious Diseases...

Completed

Virologic and Immunologic Activity of Continued Lamivudine (3TC) vs Delavirdine (DLV) in Combination With Indinavir (IDV) and Zidovudine (ZDV) or Stavudine (d4T) in 3TC-Experienced Subjects

HIV Infections

United States, Puerto Rico
AbbVie (prior sponsor, Abbott)

Completed

Safety of Lopinavir/Ritonavir (Kaletra) in HIV/HCV Co-infected Subjects vs Baseline Liver Biopsy Metavir Score

HIV Infection

Puerto Rico
Glaxo Wellcome

Completed

A Study of Retrovir and Epivir Alone or in Combination With 141W94 in HIV-Infected Patients

HIV Infections

United States
Pharmacia and Upjohn

Completed

A Study of Two Anti-HIV Drug Combinations in HIV-Infected Patients

HIV Infections

United States
Merck Sharp & Dohme LLC

Completed

The Effectiveness of HIV RNA Viral Load Testing in Determining Treatment Type in HIV-Infected Patients

HIV Infections

United States
Makerere University
Infectious Diseases Institute, Uganda

Unknown

Nucleosides And Darunavir/Dolutegravir In Africa (NADIA)

Human Immunodeficiency Virus

Uganda
ADRIANO LAZZARIN, MD
Ministero della Salute, Italy

Unknown

Implication for Strategies of Long Term Control of Viral Replication in Patient With Primary HIV Infection (PHI). (P25-INACTION)

HIV-1-infection

Italy
Hospital Clinic of Barcelona

Completed

Study Comparing Two Alternatives of Antiretroviral Therapy as Post-exposure Prophylaxis to HIV-1: Tenofovir + Emtricitabine + Lopinavir/Ritonavir Versus Tenofovir + Emtricitabine + Raltegravir (RAL-PEP) (RAL-PEP)

HIV Infection

Spain
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Safety and Effectiveness of Ritonavir Plus Lamivudine Plus Zidovudine in HIV-Infected Pregnant Women and Their Babies

HIV Infections | Pregnancy

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

A Study of Ritonavir (an Anti-HIV Drug) in HIV-Positive Infants and Children

HIV Infections

United States
Hoffmann-La Roche

Completed

A Study of Saquinavir Soft Gelatin Capsules Plus Zidovudine Plus Lamivudine in the Treatment of HIV-1 Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States
Hoffmann-La Roche

Completed

A Study of Zidovudine (AZT) Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected Patients With Little or No Previous Treatment

HIV Infections

United States, Puerto Rico
Assiut University

Unknown

Acute Kidney Injury in Newborns With Perinatal Asphyxia

Acute Kidney Injury
Abramson Cancer Center of the University of Pennsylvania
National Cancer Institute (NCI)

Terminated

Nelfinavir Mesylate, Radiation Therapy, and Temozolomide in Treating Patients With Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Bristol-Myers Squibb

Completed

Taste Assessment Study of 2 Atazanavir Powder Formulations in Healthy Subjects

HIV

United States
National Cancer Institute (NCI)

Completed

A Pilot Study of Autologous T-Cell Transplantation With Vaccine Driven Expansion of Anti-Tumor Effectors After Cytoreductive Therapy in Metastatic Pediatric Sarcomas

Rhabdomyosarcoma | Ewing's Sarcoma

United States
Dallas VA Medical Center
Merck Sharp & Dohme LLC; Tibotec Pharmaceutical Limited

Completed

Raltegravir And Darunavir Antiretroviral in Antiretroviral Naive Patients (RADAR)

HIV Infections

United States
Bristol-Myers Squibb

Completed

Study of Reyataz in HIV-infected Patients With Lipodystrophy Syndrome

HIV-Associated Lipodystrophy Syndrome

Spain, Italy, United States, Canada, France, Mexico, United Kingdom, Poland, Germany
Centre de Recherches et d'Etude sur la Pathologie...
INSERM UMR S 1136

Completed

Study Evaluating the Efficacy of a Reduced Dose Atazanavir in HIV-1-infected Patients (ATALOW)

HIV-1 Infection

France
AbbVie (prior sponsor, Abbott)

Completed

Study to Assess the Safety, Tolerability, Pharmacokinetics and Antiviral Activity of ABT-267 in HCV Infected Subjects

Chronic Hepatitis C Infection

United States
GlaxoSmithKline

Terminated

A Single Dose Pharmacokinetic (PK) and Safety Study of GSK2838232 With and Without Ritonavir (RTV) Conducted in Healthy Subjects

Infection, Human Immunodeficiency Virus

United States
University Hospital, Basel, Switzerland

Terminated

Effect of Cobicistat Versus Ritonavir Boosting on the Brain Permeation of Darunavir in HIV-infected Individuals

AIDS-related Dementia Complex

Switzerland
AbbVie

Completed

Pharmacokinetics and Safety of the Co-administration of ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 in Healthy Chinese Subjects

Healthy Volunteer

China
Fundación Huésped
Abbott

Completed

Induction-maintenance of Lopinavir/r in HIV-infected Subjects

HIV Infections

Canada, Argentina, Mexico
Boehringer Ingelheim

Completed

Dose Escalation Study of the Safety, Tolerability and Pharmacokinetics of BILR 355 BS Plus Low Dose Ritonavir in HIV-uninfected Male Volunteers

Healthy
Boehringer Ingelheim

Completed

The Pharmacodynamic/Pharmacokinetic Interaction of Tipranavir and Ritonavir With Loperamide in Healthy Volunteers

Healthy

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