Search clinical trials for: Human thrombin

Total 3920 results

Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Completed

Safety and Efficacy of Topical Recombinant Human Thrombin(rhThrombin) for Surgical Hemostasis

Surgical Hemostasis

China
ZymoGenetics

Completed

Study of Recombinant Human Thrombin for Bleeding During Surgery

Surgical Hemostasis

United States
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Completed

Topical rhThrombin as an Adjunct to Hemostasis During Segmental Hepatectomy

Hepatectomy

China
Vascular Solutions LLC
King Pharmaceuticals is now a wholly owned subsidiary of Pfizer

Completed

Evaluation of an Absorbable Surgical Hemostatic Agent: Thrombi-Gel® Versus Gelfoam-Thrombin (Control)

Operation Site Bleed

United States
Ethicon, Inc.
OMRIX Biopharmaceuticals

Completed

A Study to Compare Human Thrombin Against Bovine Thrombin in Its Ability to Stop Bleeding After Surgery

Cardiovascular, Neurologic (Spine), and General Surgery

United States
Nycomed

Completed

Observational Cohort Study of TachoSil (TC-018-IN)

Blood Loss, Surgical

Denmark
Nycomed

Completed

Non-interventional Trial About Treatment of Haemorrhages in Cholecystectomy With TachoSil (TC-027-DE)

Hemorrhage

Denmark
Nycomed

Completed

OSHES - Observational Study on Hemostasis in Surgery (TC-022-IT)

Blood Loss, Surgical | Hemostasis

Denmark
Takeda

Completed

TachoComb S Versus Standard Surgical Treatment in Surgical Resection of Renal Tumour (TC-015-IN)

Surgical Resection of Superficial Renal Tumour

Denmark
Nycomed

Completed

TachoSil Versus Standard Surgical Treatment for Air Leakage in Pulmonary Lobectomy (TC-021-IM)

Intraoperative Complications | Pulmonary Diseases

Denmark
Instituto Grifols, S.A.

Completed

Safety and Efficacy of Topical Thrombin (Human) Grifols as an Adjunct to Hemostasis During Surgery

Hemostasis

United States
Nycomed

Completed

TachoSil® Versus Standard Haemostatic Treatment of Haemorrhage in Cardiovascular Surgery (TC-023-IM)

Haemorrhage | Cardiovascular Surgery | Haemostasis

Denmark
Clinique Mutualiste Chirurgicale de la Loire

Unknown

Evicel Study on the Peri-operative Bleeding in Total Knee Prothesis Surgery

Thrombosis

France
Turku University Hospital
Helsinki University Central Hospital; Tampere University Hospital

Completed

Effect of Human Thrombin With Gelatin Matrix on Perioperative Blood Loss in Scoliosis Surgery

Adolescent Idiopathic Scoliosis

Finland
Germans Trias i Pujol Hospital

Completed

Observational Pilot Study With TachoSil as a Ventricular Sealant

Intraventricular Neoplasm

Spain
Oregon Health and Science University

Active, not recruiting

Prehospital Kcentra for Hemorrhagic Shock

Trauma Injury

United States
University Medical Center Groningen
Boehringer Ingelheim; CSL Behring

Unknown

Reversal of Dabigatran With Prothrombin Complex Concentrate

Drug Action Reversal

Netherlands
Janssen Research & Development, LLC

Completed

A Study to Evaluate Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamics of JNJ-64179375 in Healthy Male Subjects

Healthy

Belgium
Lee's Pharmaceutical Limited
Zhaoke Pharmaceutical (Hefei) Company Limited

Unknown

A Clinical Study to Evaluate the Efficacy and Safety of Hemocoagulase Injection

Hemoptysis

China
IRCCS Policlinico S. Donato

Terminated

ZEPLAST- PED: ZEro_PLASma Trial in Small Infants Undergoing Cardiac Surgery (ZEPLAST-PED)

Bleeding | Surgery--Complications | Congenital Heart Disease | Transfusion-Related Acute Lung Injury | Cardiac Defect | Fibrinogenopenia; Acquired | Transfusion-Associated Circulatory Overload

Italy
Chinese Academy of Medical Sciences, Fuwai Hospital
Peking Union Medical College Hospital; Guizhou Provincial People's Hospital; Beijing... and other collaborators

Not yet recruiting

Efficacy of Prothrombin Complex Concentrate Reducing Perioperative Blood Loss in Cardiac Surgery

Cardiac Surgical Procedures
Mayo Clinic
CSL Behring

Completed

PCC vs. FFP for Post Cardiopulmonary Bypass Coagulopathy and Bleeding

Bleeding | Blood Loss, Surgical | Cardiovascular Surgical Procedures | Prothrombin Complex Concentrates | Fresh Frozen Plasma

United States
CSL Behring
Kaiser Permanente

Completed

An Observational Cohort Study to Investigate the Risk of Thromboembolic Events in Patients Receiving Kcentra® or Plasma to Reverse Vitamin K Antagonist (VKA) Therapy in the Setting of Acute Major Bleeding

Hemorrhage

United States
Kathirvel Subramaniam
University of Maryland, Baltimore; CSL Behring

Recruiting

Administration of Prothrombin Complex Concentrate vs. Standard Transfusion During/After Heart Transplantation (OPSTAHT)

Heart Failure，Congestive | Heart Disease End Stage

United States
Grifols Italia S.p.A
Thrombinoscope

Unknown

Thrombin Generation Assay (TGA) as Predictive Test for Haemostatic. Effectiveness of FVIII Concentrates in Haemophiliac A With Inhibitors (PredicTGA)

Severe Hemophilia A With Inhibitor

Italy
Queen Mary Hospital, Hong Kong

Recruiting

The Use of Thrombin Generation Assay in Detection of Central Line Related Thrombosis (CRT) in Critically Ill Patients (THROM-CRIT)

Central Line Complication | Thrombosis, Venous

Hong Kong
Hospices Civils de Lyon

Recruiting

Cancer-related Thromboembolic Disease (PROSPECT)

Adenocarcinoma

France
Nycomed

Completed

Assess Efficacy and Safety of TachoComb H vs. Standard Surgical Treatment (i.e. Suturing) in Patients Undergoing Prostatectomy (TC-017-AU)

Control of Local Bleeding in Patients Undergoing Prostatectomy.

Denmark
Medical University of Vienna
Medical Scientific Fund of the Mayor of Vienna

Completed

Thrombomodulin-modified Thrombin Generation Assay (TGA-TM) in Patients With Critical Infections

Critical Illness | Covid19 | Sars-CoV2 | Viral Infection | Disseminated Intravascular Coagulation | Coagulation Disorder, Blood

Austria
Rennes University Hospital
Medtronic

Terminated

Prevention of Endoleaks Using Autologous Platelet Gel on Unruptured Abdominal Aortic Aneurysms

Abdominal Aortic Aneurysms

France
University of Witwatersrand, South Africa

Terminated

Safety And Efficacy Of Topical Platelet Rich Plasma And Thrombin Coagulum

Stasis Ulcer

South Africa
University of Hertfordshire
East and North Hertfordshire NHS Trust

Unknown

Assessment of Thrombotic Status in Patients With Acute Coronary Syndrome

Acute Coronary Syndrome

United Kingdom
Ethicon, Inc.

Completed

Hemostatic Matrix in Endoscopic Sinus Surgery

Sinusitis

United States
Hospices Civils de Lyon

Unknown

TGA (Thrombin Generation Assay) and Prophylaxis in Haemophilia (HOPE)

Haemophilia A

France
Octapharma

Completed

Study of Octaplex (Human Prothrombin Complex Concentrate) and Fresh Frozen Plasma in Patients Under Vitamin K Therapy Antagonist Needing Urgent Surgery or Invasive Procedures

Reversal of Anticoagulant Treatment

United States
Aronora, Inc.

Completed

Safety and Tolerability Study of E-WE Thrombin in Healthy Adult Subjects

Thrombosis

United States
BILLOIR

Recruiting

Study of Erythrocyte Parameters and Hypercoagulability in Sickle Cell Disease (SCD-TGA) (SCD-TGA)

Sickle Cell Disease | Vaso-occlusive Crisis

France
Centre Hospitalier Universitaire de Saint Etienne
LEO Pharma; Ligue contre le cancer, France; Diagnostica Stago

Not yet recruiting

Thrombin Generation Parameters and Bleeding in Patients Treated With Anticoagulants for Cancer Associated Thrombosis (CATforCAT)

Cancer | Thrombosis | Pulmonary Embolism

France
Erasmus Medical Center
Roche Diagnostics

Recruiting

ADAPT Transcatheter Aortic Valve Intervention (TAVI & Chronic Total Occlusion Percutaneous Coronary Intervention (CTO PCI) (ADAPT)

Transcatheter Aortic Valve Replacement | Percutaneous Coronary Intervention

Netherlands
Enzyre B.V.
Instytut Hematologii i Transfuzjologii, Warschau, Poland

Completed

Real-life Clinical FEIBA Samples Measured Using the Version A of the HemA EnzySystem

Hemophilia A | Hemophilia A With Inhibitor

Poland
Asan Medical Center

Unknown

Effect of Thrombin-containing Collagen-based Hemostatic Matrix (TCM)

Pancreatic Tumor

Korea, Republic of
Aronora, Inc.
Celerion

Completed

Safety and Efficacy Study of AB002 (E-WE Thrombin) in End Stage Renal Disease Patients on Chronic Hemodialysis

Thrombosis | End Stage Renal Disease

United States
Asan Medical Center

Unknown

The Effect of Application of TachoSil® in Pancreatoduodenectomy

Pancreatic Neoplasm | Pancreatic Periampullary Cancer | Pancreatic Bordeline Tumor

Korea, Republic of
Queen Mary Hospital, Hong Kong

Recruiting

DIC Markers and Thrombin Generation Parameters in Patients on ECMO Support: a Pilot Study (DIC-ECMO)

Extracorporeal Membrane Oxygenation Complication | Extracorporeal Circulation; Complications

Hong Kong
Centre Hospitalier Universitaire de Saint Etienne

Recruiting

In Vitro Correction of Thrombin Generation by Concizumab (Anti-TFPI) for Severe Hemophilia Patients

Hemophilia

France
University Hospital, Geneva

Recruiting

Bleeding of Unknown Cause: a Swiss Case-control Study (SWISS-BUC)

Bleeding Disorder

Switzerland
Maisonneuve-Rosemont Hospital

Completed

FloSeal in CRS and HIPEC

Peritoneal Carcinomatosis

Canada
Lund University
Shire

Completed

Evaluation of a Standardized Protocol for Thrombin Generation Assay

Hemophilia A

Sweden
The Hospital for Sick Children
Synapse B.V. Research Institute, University of Maastricht

Unknown

Point-of-care Assessment of Thrombin Generation and Platelet Function in Children Requiring Cardiopulmonary Bypass

Platelet Function Tests | Thrombin Generation Tests | Perioperative Coagulopathy

Canada
University Hospital, Grenoble

Completed

Early Administration of Prothrombin Concentrate Complex in Patients With Acute Hemorrhage Following Severe Trauma (PROCOAG)

Shock, Hemorrhagic

France

Search clinical trials for: Human thrombin

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