Search clinical trials for: INS115644 Ophthalmic Solution

Total 19583 results

University of Santiago de Compostela

Unknown

Methodology Antiseptic Application, Influence on Oral Biofilm.

Periodontitis | Gingivitis | Oral Biofilm

Spain
TC Erciyes University

Completed

Controlled Hypotension During Functional Endoscopic Sinus Surgery

Hemorrhage
Fovea Pharmaceuticals SA

Completed

Evaluation of Efficacy of Coadministration of FOV1101-00 and Prednisolone Acetate in Patients With Mild Ongoing Ocular Allergic Inflammation

Allergic Conjunctivitis

United States
Hellenic Institute for the Study of Sepsis

Completed

Anti-inflammatory Action of Oral Clarithromycin in Community-acquired Pneumonia (ACCESS)

Sepsis | Mortality | Inflammatory Response | Biomarkers | SIRS | Community-acquired Pneumonia

Greece
University of Roma La Sapienza

Unknown

Effect of Allopurinol on Mono and Co-administration With Statins on Platelets Reactivity on Diabetic Patiets Treated With Aspirin and Insulin

Diabetes Mellitus Type 2 Platelets Reactivity Statin

Italy
Dizal Pharmaceuticals

Recruiting

Assessing the Effect of DZD9008 on the Pharmacokinetics of the Cocktail Probes Representative for CYP3A4, P-gp, BCRP and OATP1B1 in Patients With EGFR or HER2 Mutant Advanced Non-small Cell Lung Cancer (WU-KONG19)

Non-small Cell Lung Cancer

China
University of California, San Francisco
Research to Prevent Blindness

Active, not recruiting

Parasitic Ulcer Treatment Trial Pilot

Acanthamoeba Keratitis

India
Takeda

Completed

A Study of Soticlestat With Itraconazole and Mefenamic Acid in Healthy Adults

Healthy Volunteers

United States
University at Buffalo
The VA Western New York Healthcare System

Completed

Optimal Timing of Intercostal Nerve Blocks During Video-Assisted Thoracic Surgeries

Video-Assisted Thoracic Surgery | Video-Assisted Thoracoscopic Surgery

United States
Mogilev Regional Clinical Hospital

Completed

Sciatic Nerve Blockade by Subgluteal Access 12.5 ml of 1% Lidocaine: US Guidance Versus US Guidance With Electrical Stimulation of Peripheral Nerves (Influence of the Sciatic Nerve Blockade on the Effectiveness of Small Doses of Local Anesthetic.). (EPBwEPN)

Ultrasonography | Sciatic Nerve | Nerve Block | Efficiency | Minimum Effective Dose

Belarus
Sanofi

Completed

Comparison of Two Treatment Regimens in Patients With Type 2 Diabetes After Short-term Intensive Insulin Therapy (SWITCH)

Type 2 Diabetes Mellitus

China
Sanofi

Completed

A Trial of Caplacizumab in Japanese Patients With Acquired Thrombotic Thrombocytopenic Purpura (aTTP)

Thrombotic Thrombocytopenic Purpura

Japan
Baxalta now part of Shire

Completed

Tolerability and Safety of Immune Globulin Subcutaneous Solution (IGSC) and rHuPH20 in PID

Primary Immunodeficiency Diseases (PID)

United States
Nourhan M.Aly
Alexandria University

Completed

Nebulized Midazolam, Dexmedetomidine, and Their Combination in Sedation of Preschoolers Undergoing Dental Treatment

Dental Anxiety

Egypt
Beijing Tiantan Hospital

Unknown

Effects of Pre-emptive Scalp Infiltration With Ketorolac and Ropivacaine for Post-craniotomy Pain

Pain | Supratentorial Brain Tumor
Boehringer Ingelheim

Completed

Effectiveness of Two Different Doses of BI 1026706 on the Overall Peak-to-Peak (PtP) N2/P2-component Amplitude of Laser (Somatosensory, Radiant-heat) Evoked Potentials (LEP) in UVB(Ultraviolet)-Irradiated Skin in Healthy Male Volunteers

Healthy

Germany
St. Olavs Hospital

Completed

The Effect of Topical Administration of Common Drugs on Postoperative Bleeding and Pain

Pain, Postoperative | Postoperative Hemorrhage

Norway
Millennium Pharmaceuticals, Inc.

Completed

Effects of Fluconazole and Itraconazole CYP3A-Mediated Inhibition on the Pharmacokinetics, Safety, and Tolerability of MLN4924 in Participants With Advanced Solid Tumors

Advanced Solid Tumors

United States
Palo Alto Medical Foundation

Completed

To Study the Effectiveness and Safety of Niacin and a Topical Steroid Eye Drop to Treat Retinal Vein Occlusions

Retinal Vein Occlusion

United States
Sanofi
Regeneron Pharmaceuticals

Completed

A Study Assessing the Safety and Efficacy of Sarilumab Added to Non-MTX DMARDs or as Monotherapy in Japanese Patients With Active Rheumatoid Arthritis (SARIL-RA-HARUKA)

Rheumatoid Arthritis

Japan
Medical University of Silesia
Silesian University of Medicine

Completed

SPI-directed Analgesia for Vitreoretinal Surgeries (SPIVS)

Postoperative Pain | Postoperative Nausea and Vomiting | Vitreoretinal Surgeries

Poland
Sanofi
Regeneron Pharmaceuticals

Terminated

Effect of SAR153191 (REGN88) With Methotrexate in Patients With Active Rheumatoid Arthritis Who Failed TNF-α Blockers

Rheumatoid Arthritis

United States, Italy, Mexico, Colombia, Czechia, Spain
Bristol-Myers Squibb
AbbVie

Completed

Study of Elotuzumab in Combination With Lenalidomide and Dexamethasone in Subjects With Multiple Myeloma and Various Levels of Renal Function

Multiple Myeloma

United States
Silesian University of Medicine

Completed

Thoracic Paravertebral Block in Pain Management After Renal Surgery

Postoperative Pain

Poland
Bristol-Myers Squibb

Completed

Anti-CXCR4 (BMS-936564) Alone and in Combination With Lenalidomide/Dexamethasone or Bortezomib/Dexamethasone in Relapsed/Refractory Multiple Myeloma

Multiple Myeloma

United States
Tonix Pharmaceuticals, Inc.

Completed

Comparative Bioavailability of Sublingual TNX-102, Oral and Intravenous Cyclobenzaprine in Healthy Adults

Healthy Adults

Canada
Cork University Hospital

Completed

To Compare lidocaine2%/Clonidine in Combination, With Bupivacaine 0.5 % Alone in Equal Volumes for Combined Sciatic-saphenous Nerve Block in Terms of Selectivity of Blockade

Bimalleolar Fractures of the Ankle. | Sciatic Nerve Block. | Saphenous Nerve Block. | Post Operative Analgesia Duration.

Ireland
Johann Wolfgang Goethe University Hospital

Unknown

Status of Growth Hormone/ Insulin-like Growth Factor-1 (GH/IGF-1) Axis and Growth Failure in Ataxia Telangiectasia (AT) (GHAT)

Growth Failure | Ataxia Telangiectasia

Germany
Sanofi Pasteur, a Sanofi Company

Recruiting

Co-administration Study of an Investigational Live-Attenuated Respiratory Syncytial Virus Vaccine in Infants and Toddlers (CORAL)

RSV Immunization

United States, Puerto Rico
Emory University
American Association for Hand Surgery: AAHS

Recruiting

Ketorolac in Upper Extremity Tendinopathy and Arthropathy

Osteoarthritis | Tendinopathy | Arthropathy

United States
Sohag University

Recruiting

Nebulized Magnesium Sulfate and Sildenafil for Persistent Pulmonary Hypertension of Newborn

Persistent Pulmonary Hypertension of Newborn

Egypt
Naveen Poonai

Recruiting

Intranasal Dexmedetomidine Plus Ketamine for Procedural Sedation (Ketodex)

Fracture | Dislocation

Canada
Janssen Vaccines & Prevention B.V.

Completed

A Study to Evaluate the Safety and Immunogenicity for Regimen Selection of Ad26.RSV.preF and/or RSV preF Protein Combinations Followed by Expanded Safety Evaluation in Adults Aged 60 Years and Older

Healthy

United States
mohamed
Azhar University

Completed

Comparisons Between Dexmedetomidine and Magnesium Sulfate in Controlled Hypotension During Rhinoplasty Surgeries

Hypotension

Egypt
Bristol-Myers Squibb
AbbVie

Completed

Phase III Study of Lenalidomide and Dexamethasone With or Without Elotuzumab to Treat Relapsed or Refractory Multiple Myeloma (ELOQUENT - 2)

Lymphoma | Multiple Myeloma

United States, Belgium, France, Germany, Italy, Japan, United Kingdom, Australia, Poland, Puerto Rico, Canada, Denmark, Hungary, Israel, Spain, Czechia, Ireland, Austria, Switzerland, Greece, Turkey, Romania, United Arab Emirates
Isfahan University of Medical Sciences

Completed

Peri-Articular-Multimodal Drug and Oral Celecoxib in Management of Postoperative Pain of Total Knee Arthroplasty

Postoperative Pain | Total Knee Arthroplasty

Iran, Islamic Republic of
Amphastar Pharmaceuticals, Inc.

Completed

Study of Drug Exposure in Systemic Circulation of Primatene Mist by Oral Inhalation, Versus Epinephrine Injection by Intramuscular Injection and ProAir by Oral Inhalation in Healthy Individuals

Asthma | Pharmacokinetics | Anaphylaxis | Epinephrine | Albuterol

United States
Sanofi
Regeneron Pharmaceuticals

Completed

An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemia

Hypercholesterolemia

Slovenia, Taiwan, Russian Federation, Canada, Netherlands, Brazil, Denmark, Mexico, Spain, Turkey
FibroGen

Completed

Evaluate the Safety and Efficacy of FG-3019 (Pamrevlumab) in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis

United States, New Zealand, India, South Africa, Australia, Bulgaria, Canada
GlaxoSmithKline

Withdrawn

Effectiveness of Fluticasone Furoate/ Umeclidinium/ Vilanterol (FF/UMEC/VI) Using the Connected Inhaler System (CIS) as Compared With Fluticasone Proprionate/ Salmeterol (FP/SAL) Plus Tiotropium (TIO) in Inadequately Controlled Asthma

Asthma
Vastra Gotaland Region
Uppsala University; Gothia Forum - Center for Clinical Trial

Completed

A Study of the Effect of Epinephrine on Platelet Reactivity in Subjects Treated With Ticagrelor

Healthy Volunteers

Sweden
Massachusetts Eye and Ear Infirmary

Completed

Safety and Efficacy of Topical Tacrolimus 0.05% in the Treatment of Ocular Graft-Versus-Host Disease

Ocular GVHD

United States
British Columbia Cancer Agency
Hoffmann-La Roche

Completed

Systemic and Topical Treatments for Rash Secondary to Erlotinib in Lung Cancer (LUTRAERL)

Rash

Canada
Egalet Ltd

Completed

Study to Assess the PK of Ketorolac Tromethamine Intranasal and to Assess the Effects of a Oxymetazoline Hydrochloride on the PK of Ketorolac Tromethamine

Assess Pharmacokinetics of Ketorolac Tromethamine Intranasal and Assess Effects of a Oxymetazoline Hydrochloride on the PK of Ketorolac Tromethamine

United Kingdom
maximiliano barahona vasquez

Unknown

Gonyautoxins Local Periarticular Injection for Pain Management After Total Knee Arthroplasty (Toxin)

Pain Management | Knee Arthroplasty

Chile
Medical University of Vienna

Terminated

Perioperative Fluid Management in Patients Receiving Major Abdominal Surgery - Effects of Normal Saline Versus an Acetate Buffered Balanced Infusion Solution on the Necessity of Catecholamines for Cardiocirculatory Support (KATECHOL)

Critical Illness

Austria
Janssen R&D Ireland

Completed

A Study to Evaluate the Safety, Tolerability, and Effectiveness of a 12-Week Combination Therapy of TMC647055 and TMC435 With and Without GSK23336805 With a Pharmacokinetic Enhancer With and Without Ribavirin in Patients Infected With Chronic Genotype 1 Hepatitis C Virus

Chronic Hepatitis C

Belgium, Germany
Novartis Vaccines

Completed

Prevention, Randomized, Open Label, Active Control, Parallel Assignment, Safety/Efficacy Study

Healthy

United Kingdom
Emergency NGO Onlus

Withdrawn

Clinical Study to Assess Efficacy and Safety of Amiodarone in Treating Patients With Ebola. Virus Disease (EVD) in Sierra Leone. EASE (EMERGENCY Amiodarone Study Against Ebola) (EASE)

Ebola Virus Disease
Tesaro, Inc.

Completed

An Open Label, Single Dose, Three Part Study to Assess the Effects of Rolapitant (2 mg/mL IV Solution) on the Pharmacokinetics of Digoxin; Sulfasalazine; and the Cooperstown Cocktail (Midazolam, Omeprazole, Warfarin, Caffeine, and Dextromethorphan in Healthy Subjects

Chemotherapy-induced Nausea and Vomiting

United States

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