Search clinical trials for: Identification of drug adverse effect

Total 144712 results

Wyeth is now a wholly owned subsidiary of Pfizer

Completed

An Open Parallel Study to Determine the Optimum Dosing Schedule for AS-101 in AIDS/ARC Patients

HIV Infections

United States
Janssen R&D Ireland

Completed

A Study to Investigate the Effect of Steady-State TMC278 on the Pharmacokinetics of a Single Dose of Digoxin

Healthy

Belgium
Merck Sharp & Dohme LLC

Completed

Safety and Pharmacokinetics of Oral Islatravir (MK-8591) Once Monthly in Participants at Low Risk of Human Immunodeficiency Virus 1 (HIV-1) Infection (MK-8591-016)

HIV-1 Infection

United States, Israel, South Africa
Gruppo Italiano Malattie EMatologiche dell'Adulto

Recruiting

The Incidence of Hepatitis B in Diffuse Large B-Cell Lymphoma/Chronic Lymphoid Leukemia HBsAg-positive Treated With Rituximab, Chemotherapy and Tenofovir Alafenamide (CLL1818)

Chronic Lymphoid Leukemia | Large-B-cell Diffuse Lymphoma

Italy
National Institute of Allergy and Infectious Diseases...

Completed

A Study of AS-101 in Patients With AIDS or AIDS Related Complex (ARC)

HIV Infections

United States
Queen's University

Completed

The Effect of Exercise on Recent Onset Low Back Pain in the Emergency Department

Low Back Pain

Canada
Maulana Azad Medical College

Completed

A Randomized Controlled Trial of Lamivudine in Acute Hepatitis B

Hepatitis B

India
Assiut University

Not yet recruiting

Diabetes In Relation to Hospitalized COVID-19 Patents At Assiut University Hospital

COVID-19 | Diabetes Mellitus
Erasme University Hospital

Recruiting

Study of Atelectasis by Electrical Impedance Tomography

Urologic Surgical Procedures | Gynecologic Surgical Procedures

Belgium
Tibotec Pharmaceuticals, Ireland

Completed

An Open-label Trial With TMC125 in Patients Who Have Virologically Failed in a DUET Trial (TMC125-C206 or TMC125-C216).

HIV-1

United States, Canada, France, Belgium, Germany, Spain, Argentina, Chile, Panama, Brazil, Puerto Rico, Thailand, Mexico, Australia
Tibotec Pharmaceuticals, Ireland

Completed

TMC125-C223: TMC125 in HIV-1 Infected Subjects

HIV Infection
Pharmasset

Terminated

Efficacy and Safety of Clevudine Compared With Adefovir in Patients With Chronic Hepatitis Due to Hepatitis B Virus (QUASH2)

Hepatitis B | Chronic Hepatitis

United States, Canada, China, Argentina, Taiwan, Spain, Puerto Rico, Australia, Greece, Thailand, United Kingdom
Tibotec Pharmaceuticals, Ireland

Completed

The TMC125-C214 Study Provides Early Access to TMC125 for HIV-1 Infected Patients Who Have Failed Multiple Antiretroviral Regimens and Will Also Gather Information on the Long-term Safety and Tolerability of TMC125 Combined With Other Antiretroviral Drugs

HIV-1

United States, Belgium, Germany, Taiwan, Spain, Mexico, Turkey, Canada, Netherlands, Denmark, Greece, Sweden, Korea, Republic of, Russian Federation, Puerto Rico, Luxembourg
Eisai Co., Ltd.

Completed

An Study of Efficacy and Safety of Clevudine

Chronic Hepatitis B

China
Tibotec Pharmaceuticals, Ireland

Completed

TMC125HIV1083 - Swallowability of Uncoated 200 mg Etravirine Tablets in HIV-1 Infected Patients

HIV-Infections
Tibotec Pharmaceuticals, Ireland

Completed

TMC125-C203: Phase II Randomized (Patients Are Assigned Different Treatments Based on Chance), Placebo Controlled Dose Escalating Trial of TMC125 in HIV-1 Infected Patients

HIV-1 | Anti-Retroviral Agents
First Affiliated Hospital of Guangxi Medical University

Recruiting

Combination of Henagliflozin and Continuous Subcutaneous Insulin Infusion in T2DM

Type2diabetes

China
Eisai Co., Ltd.

Completed

A Single and Multiple Dose Study of Dotinurad in Chinese Healthy Participants

Healthy Volunteers

China
HemCon Medical Technologies, Inc

Terminated

Chitosan Dressings to Facilitate Safe Effective Debridement of Chronic Wounds & Minimize Wound Bacterial Re-colonization

Wound Debridement

United States
Northwell Health
Cohen Children's Medical Center

Available

A Compassionate Use/Expanded Access Protocol Using 131I-MIBG Therapy for Patients With Refractory Neuroblastoma and Metastatic Pheochromocytoma

Neuroblastoma | Pheochromocytoma

United States
IRCCS Eugenio Medea
University of Rome Tor Vergata

Completed

Safety and Efficacy of Etravirine in Friedreich Ataxia Patients (FAEST1)

Friedreich Ataxia

Italy
Gilead Sciences

Completed

Observational Study of the Durability of Seroconversion Chronic HBV Patients Who Seroconverted in a Previous Gilead-Sponsored Study of ADV.

Hepatitis B
Tibotec Pharmaceuticals, Ireland

Completed

TMC125-TiDP2-C187: A Phase I, Open-label Trial to Investigate the Pharmacokinetic Interaction Between TMC125 and Two Antifungal Agents (Fluconazole and Voriconazole), All at Steady-state in Healthy Subjects.

Fungal Infection | HIV | AIDS
Tibotec Pharmaceuticals, Ireland

Completed

TMC125-C211: Trial of TMC125 in HIV-1 Infected Subjects Who Were in a Sponsor Selected TMC125 Trial

HIV Infection
Gilead Sciences

Terminated

Continued Access Study of Adefovir Dipivoxil (ADV) for Patients w/Chronic HBV Infection.

Hepatitis B
BioMAS Ltd

Unknown

Safety and Efficacy Double Blind Vehicle Controlled Study of 15% AS101 Gel to Treat External Genital Warts

External Genital Warts

Israel
PharmaKing

Completed

Efficacy and Safety of Oltipraz for Liver Fat Reduction in Patients With Non-Alcoholic Fatty Liver Disease Except for Liver Cirrhosis

Non-alcholic Fatty Liver Disease

Korea, Republic of
Chosun University Hospital

Completed

ONSD According to the Position During Laparoscopy (ONSD)

Cervical Cancer | Ovarian Cancer | Cholecystitis | Uterine Myoma | Ovarian Cyst

Korea, Republic of
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

ARQ 501 in Combination With Gemcitabine in Subjects With Pancreatic Cancer

Adenocarcinoma | Pancreatic Cancer

United States
G D Searle

Completed

Initial Phase II Efficacy and Safety Study of SC-48334 Administered in Combination With Low-Dose Zidovudine (AZT) to Symptomatic HIV-1 Infected Patients With = or > 200 to = or < 500 CD4+ Cells/mm3

HIV Infections

United States
G D Searle

Completed

Phase II Study of the Safety and Surrogate Marker Efficacy of Butyldeoxynojirimycin (SC-48334) and AZT in Symptomatic HIV-1 Infected Patients With 200 - 500 CD4+ Cells/mm3. (NOTE: Asymptomatic HIV-1 Infected Patients Also Eligible)

HIV Infections

United States
Johann Wolfgang Goethe University Hospital
Gilead Sciences

Unknown

A Pilot Study of Triple NtRTI/NsRTI Therapy in Antiretroviral Naive HIV-1 Infected Patients

HIV

Germany
Florida Atlantic University
Advanced Diabetes Treatment Centers; Global Infusions

Terminated

Effects of Pulsatile Insulin Delivery on Diabetic Neuropathy in Patients With Types 1 and 2 Diabetes Mellitus

Diabetes Mellitus, With Complications

United States
National Institutes of Health Clinical Center (CC)

Completed

Drug Interaction Study Between Inhaled Beclomethasone and Protease Inhibitors in Healthy Volunteers

Asthma | HIV

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Tolerability of Etravirine in HIV-1 Infected Infants and Children

HIV Infections

United States, Brazil, South Africa
Tibotec Pharmaceuticals, Ireland

Completed

TMC125-C206: A Phase III Study to Investigate the Efficacy, Tolerability and Safety of TMC125 as Part of an Antiretroviral Regimen, Including TMC114/Ritonavir and an Investigator-selected Optimized Background, in HIV-1 Infected Patients With Limited to no Treatment Options.

HIV

United States, France, Argentina, Chile, Mexico, Costa Rica, Panama, Brazil, Puerto Rico, Thailand
National Institute of Allergy and Infectious Diseases...

Completed

Evaluation of the Interaction Between Acetaminophen and Zidovudine

HIV Infections

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Terminated

Surgery, Gemcitabine, Cisplatin, and Radiation Therapy in Treating Patients With Stage II or Stage III Non-Small Cell Lung Cancer

Lung Cancer
BioMAS Ltd

Suspended

Safety and Efficacy Study of AS101 to Treat Elderly Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Patients

Acute Myeloid Leukemia | Myelodysplastic Syndrome

Israel
South Plains Oncology Consortium

Terminated

Fenretinide/LXS Oral Powder Plus Ketoconazole in Recurrent Ovarian Cancer

Ovarian Cancer | Cancer of the Ovary | Primary Peritoneal Carcinoma | Ovary Neoplasms | Cancer of Ovary

United States
Medical University of Vienna

Completed

Local Tolerability of Chitosan-N-acetylcysteine Eye Drops in Healthy Young Volunteers

Dry Eye Syndromes

Austria
University of Colorado, Denver

Completed

Potential for Drug-drug Interactions Between Boceprevir and Etravirine in HIV/Hepatitis C Virus Negative Volunteers

Hepatitis C | HIV

United States
Tibotec Pharmaceuticals, Ireland

Completed

TMC125-C216: A Phase III Study to Investigate the Efficacy, Tolerability and Safety of TMC125 as Part of an Antiretroviral Regimen, Including TMC114/Ritonavir and an Investigator-selected Optimized Background, in HIV-1 Infected Patients With Limited to no Treatment Options.

HIV
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

ARQ 501 in Subjects With Cancer

Cancer

United States
National Institute of Allergy and Infectious Diseases...

Completed

Adefovir Dipivoxil to Treat Hepatitis B in HIV-Infected Patients

HIV Infection | Hepatitis B

United States
Pharmacia and Upjohn

Completed

Prospective Open-Label Study of the Emergence of Drug Resistance in Patients Infected With HIV-1 Who Are Taking Oral U-87201E

HIV Infections

United States
Instituto de Investigacion Sanitaria La Fe
Sociedad Española de Neumología y Cirugía Torácica; Sociedad Valenciana de... and other collaborators

Recruiting

Duration of Antibiotic Treatment in Community-acquired Pneumonia (ADAPT)

Community-acquired Pneumonia

Spain
Assiut University

Unknown

Effect of Direct AntiViral Drugs of Chronic HCV on eGFR in Assuit Universiry Hospital

Antiviral Drug
Shire

Terminated

A Study Comparing the Pharmacokinetics and Palatability of Two Candidate Pediatric Powder-for-Oral-Suspension Formulations of Maribavir to the Current Maribavir Tablet Formulation Administered in Healthy Adult Participants

Healthy Volunteers

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Terminated

Vaccine Therapy in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia

Leukemia

United States

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