Search clinical trials for: Immunosuppressive Agents

Total 188979 results

Meng Qiu

Recruiting

The Efficacy and Safety of a Compound Glutamine Capsule in the Prevention of Chemotherapy-induced Mucositis

Mucositis | Chemotherapeutic Toxicity

China
Grifols Therapeutics LLC

Recruiting

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Two Different Doses of Alpha1-Proteinase Inhibitor Subcutaneous (Human) 15% in Participants With Alpha1-Antitrypsin Deficiency

Alpha1-Antitrypsin Deficiency

United States
University of Birmingham
University of Oxford; University Hospital Birmingham NHS Foundation Trust; London... and other collaborators

Recruiting

Preventing Stroke, Premature Death and Cognitive Decline in a Broader Community of Patients With Atrial Fibrillation (DaRe2THINK)

Atrial Fibrillation

United Kingdom
Medical University of Warsaw

Recruiting

TMAO in Patients With Severe Aortic Stenosis (TASTE)

Heart Failure | Aortic Stenosis

Poland
AstraZeneca

Recruiting

A Study of Osimertinib With or Without Chemotherapy Versus Chemotherapy Alone as Neoadjuvant Therapy for Patients With EGFRm Positive Resectable Non-Small Cell Lung Cancer (NeoADAURA)

Non-Small Cell Lung Cancer

China, United States, Chile, Vietnam, Thailand, Brazil, Bulgaria, Canada, Germany, India, Japan, Korea, Republic of, Poland, Russian Federation, Singapore, Turkey, Austria, Israel, Spain, Taiwan, Mexico, France, Italy, Peru, Switzerland, United...
Mark Vincent
AstraZeneca

Recruiting

Osimertinib Then Chemotherapy in EGFR-mutated Lung Cancer With Osimertinib Third-line Rechallenge (OCELOT)

Non-Small Cell Lung Cancer

Canada
Actelion

Recruiting

Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension (UNISUS)

Pulmonary Arterial Hypertension

Belgium, United States, Italy, Canada, Taiwan, Greece, China, Korea, Republic of, Germany, Israel, Austria, Russian Federation, Australia, Thailand, United Kingdom, Brazil, Spain, Ukraine, Bulgaria, Colombia, Mexico, Turkey, Vietnam, ... and more
University of Alabama at Birmingham

Recruiting

Smoking Reduction In Gravid Substance Use Disorders (SIGS)

Tobacco Smoking | Tobacco Use Disorder | Tobacco Smoking in Mother Complicating Pregnancy

United States
Northwestern University

Recruiting

Aging Program Project Grant 6 (PPG6)

Improving Cardiometabolic Outcomes in Older Adults

United States
Shanghai Pulmonary Hospital, Shanghai, China

Recruiting

Surgery With or Without Chemotherapy for Stage I NSCLC With Micropapillary Component ≥ 20%

Treatment | Histological Type of Neoplasm | Lung Adenocarcinoma, Stage I | Chemotherapy, Adjuvant

China
Ohio State University Comprehensive Cancer Center

Recruiting

Beating Lung Cancer in Ohio Protocol in Improving Survival in Patients With Stage IV Non-Small Cell Lung Cancer (BLCIO)

Current Smoker | Lung Adenocarcinoma | Stage IV Non-Small Cell Lung Cancer | Squamous Cell Lung Carcinoma | Cigarette Smoker

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Ruxolitinib Phosphate and Azacytidine in Treating Patients With Myelofibrosis or Myelodysplastic Syndrome/Myeloproliferative Neoplasm

Primary Myelofibrosis | Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable | Polycythemia Vera, Post-Polycythemic Myelofibrosis Phase | Myelofibrosis Transformation in Essential Thrombocythemia

United States
Medtronic Diabetes

Active, not recruiting

Evaluation of the MiniMed 780 System in Paediatric Subjects (LENNY)

Diabetes type1 | Children, Only

Italy, United Kingdom, Finland, Slovenia
Emoled

Completed

EmoLED Medical Device Treatment of Second and Third Stage Pressure Ulcers (RISE_UP)

Pressure Ulcer | Pressure Ulcers Stage II | Pressure Ulcers Stage III | Pressure Sore

Italy
Memorial Sloan Kettering Cancer Center
M.D. Anderson Cancer Center; Mayo Clinic; Brigham and Women's Hospital; Princess...

Active, not recruiting

Pleurectomy/Decortication (Neo) Adjuvant Chemotherapy and Intensity Modulated Radiation Therapy to the Pleura in Patients With Locally Advanced Malignant Pleural Mesothelioma

Mesothelioma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

mTORC1/2 Inhibitor AZD2014 or the Oral AKT Inhibitor AZD5363 for Recurrent Endometrial and Ovarian

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Uterine Corpus Carcinoma | Endometrial Adenocarcinoma | Recurrent Breast Carcinoma | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Aurora Kinase Inhibitor LY3295668 in Combination With Osimertinib for the Treatment of Advanced or Metastatic EGFR-Mutant Non-squamous Non-small Cell Lung Cancer

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Advanced Lung Non-Squamous Non-Small Cell Carcinoma | Metastatic Lung Non-Squamous Non-Small Cell Carcinoma and other conditions

United States
University of Udine
Wageningen University and Research

Completed

Glycemic and Insulinemic Response of Durum Wheat Bread

Glycemic Index | Oral Processing | Glucose Response | Insulin Response

Italy
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Finasteride Tablets 5 mg and Proscar Tablets 5 mg

Healthy

United States
Superior University

Active, not recruiting

Comparison Of Resistance Training And Core Strengthening Exercises Vitamin D In Postmenopausal Women With Low Back Pain

Menopausal | Pain, Low Back

Pakistan
Sanofi

Completed

Comparison of SAR341402 to NovoLog in Adult Patients With Type 1 Diabetes Mellitus Also Using Insulin Glargine (GEMELLI X)

Type 1 Diabetes Mellitus

United States
National Cancer Institute (NCI)

Completed

Erlotinib Hydrochloride in Preventing Liver Cancer in Patients With Cirrhosis of the Liver

Hepatocellular Carcinoma | Cirrhosis

United States
University Hospital, Bordeaux

Active, not recruiting

Optimisation of Response for Organ Preservation in Rectal Cancer : Neoadjuvant Chemotherapy and Radiochemotherapy vs. Radiochemotherapy (GRECCAR12)

Rectal Cancer

France
Novartis Pharmaceuticals

Terminated

Study Evaluating Efficacy and Safety of Capmatinib in Combination With Osimertinib in Adult Subjects With Non-small Cell Lung Cancers as Second Line Therapy (GEOMETRY-E)

Carcinoma, Non-Small-Cell Lung

Japan, Korea, Republic of, Singapore
Barts & The London NHS Trust

Active, not recruiting

A Mechanistic Exploratory Study of AF-induced Cardiac Dysfunction and Symptoms

Heart Failure | Atrial Fibrillation

United Kingdom
University of Alabama at Birmingham

Completed

The Role of Pre-deployment Retraction in Decreasing Biopsy Clip Migration During Stereotactic Breast Biopsies

Breast Biopsy

United States
SCRI Development Innovations, LLC
Pfizer

Withdrawn

Lorlatinib in Combination With Chemotherapy in Participants With Metastatic Anaplastic Lymphoma Kinase Positive (ALK+) Non-small Cell Lung Cancer (NSCLC) Who Progressed on Single-agent Lorlatinib (NSCLC)

Lung Cancer | Non-small Cell Lung Cancer

United States
Sumitomo Pharma America, Inc.

Terminated

A Phase 1b/2 Study of Alvocidib Plus Decitabine or Azacitidine in Patients With MDS

Myelodysplastic Syndromes (MDS)

United States
The University of Texas Health Science Center at...
National Institute on Aging (NIA)

Withdrawn

Vestibular Function Using Mitochondrial Antioxidant Therapy

Vestibular Function Disorder

United States
Robert Wesolowski

Completed

Vaccine Therapy in Treating Patients With Metastatic Solid Tumors

Breast Cancer | Ovarian Cancer | Malignant Solid Tumour | GIST | Malignant Tumor of Colon

United States
The University of Texas Health Science Center at...

Completed

Impact of Omega 3 Fatty Acid Supplementation on Aromatase in Obese Subjects

Breast Cancer

United States
Paul S. Bernstein

Completed

Lutein & Zeaxanthin in Pregnancy - Carotenoid Supplementation During Pregnancy: Ocular and Systemic Effects (L-ZIP)

Pregnancy Related | Nutrient Deficiency

United States
Genuine Research Center, Egypt
Chemipharm Pharmaceutical Industries, Egypt

Completed

Bioequivalence Study of Modafinil From Bravamax 200 mg Scored Tablets (Chemipharm Pharmaceutical Industries, Egypt) Versus Vigil 200 mg Tablets (Teva GmbH, Germany)

Healthy

Egypt
Pfizer

Active, not recruiting

A Study Of Palbociclib (PD-0332991) + Letrozole VS. Placebo+ Letrozole For 1st Line Treatment Of Asian Postmenopausal Women With ER+/HER2- Advanced Breast Cancer [PALOMA-4]

Breast Neoplasms

China, Taiwan, Hong Kong, Singapore, Thailand
Takeda

Withdrawn

A Study of RYMPHYSIA for Alpha1-Proteinase Inhibitor (A1PI) Therapy in Adults With A1PI Deficiency and Chronic Obstructive Pulmonary Disease (COPD)-Emphysema

Chronic Obstructive Pulmonary Disease (COPD) | Alpha1-Antitrypsin Deficiency
Grifols Therapeutics LLC

Terminated

Study to Evaluate the Safety and Efficacy of Liquid Alpha1-Proteinase Inhibitor (Human) in Hospitalized Participants With Coronavirus Disease (COVID-19)

COVID-19

United States, Brazil, Chile, Colombia, Mexico
National Institute of Allergy and Infectious Diseases...

Completed

Study on the Safety and Immunogenicity of Boostrix Vaccine in Pregnant Malian Women and Their Infants

Pertussis | Tetanus | Diphtheria | Diphtheria Immunisation | Tetanus Immunisation | Clostridium Difficile Immunisation

Mali
Lexicon Pharmaceuticals
Sanofi

Terminated

Effect of Sotagliflozin on Cardiovascular and Renal Events in Participants With Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular Risk (SCORED)

Heart Failure | Chronic Kidney Diseases | Type 2 Diabetes Mellitus

Estonia, Belgium, Sweden, Italy, China, United States, Canada, Bulgaria, Chile, Denmark, Hungary, Latvia, Mexico, Russian Federation, Serbia, Spain, Portugal, Romania, Turkey, Poland, Lithuania, Argentina, Australia, Brazil, Czechia, France, Georg... and more
Lexicon Pharmaceuticals
Sanofi

Terminated

Effect of Sotagliflozin on Cardiovascular Events in Participants With Type 2 Diabetes Post Worsening Heart Failure (SOLOIST-WHF Trial)

Heart Failure | Type 2 Diabetes Mellitus

Belgium, Canada, Israel, Spain, Germany, Argentina, Chile, Hungary, Korea, Republic of, Latvia, Lithuania, Russian Federation, Sweden, Romania, Poland, Brazil, Denmark, United States, Australia, Austria, Czechia, Finland, France, Greece, Ita... and more
Istanbul University

Completed

The Effectiveness of Different Doses of Hyaluronic Acid Injections in Knee Osteoarthritis.

Knee Osteoarthritis

Turkey
Hospital Universitari Vall d'Hebron Research Institute
Vitae Health Innovation

Completed

Coenzyme Q10 Plus NADH Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CONNeCT)

Chronic Fatigue Syndrome

Spain
Narendranath Epperla

Withdrawn

Acalabrutinib and Duvelisib for the Treatment of Relapsed/Refractory Indolent Non-Hodgkin Lymphoma

Recurrent Marginal Zone Lymphoma | Recurrent Follicular Lymphoma | Refractory Follicular Lymphoma | Refractory Marginal Zone Lymphoma | Refractory Nodal Marginal Zone Lymphoma | Recurrent Nodal Marginal Zone Lymphoma | Recurrent Splenic Marginal Zone Lymphoma | Refractory Splenic Marginal Zone Lymphoma and other conditions
The First Hospital of Qinhuangdao

Completed

Effects of Thoracic Paravertebral Block Combined With S-ketamine on Postoperative Pain and Cognitive Function After Thoracoscopic Surgery

Postoperative Cognitive Dysfunction

China
Sanofi

Completed

A Bioequivalence Study Testing Two Formulations of Sotagliflozin in Healthy Male and Female Subjects Under Fasted Conditions

Type 2 Diabetes Mellitus | Healthy Subjects

United States
Sanofi

Completed

Comparison of Sotagliflozin Prototype Tablets With Reference Tablet in Healthy Subjects

Type 2 Diabetes Mellitus | Type 1 Diabetes Mellitus

Germany
University of California, Davis

Completed

Efficacy of Lipid-Based Nutrient Supplements (LNS) for Pregnant and Lactating Women and Their Infants

Anemia | Malnutrition | Stunting

Ghana
Peking University Cancer Hospital & Institute

Completed

Tailored Operative or Non-operative Management for Low-risk Rectal Cancer After Intensive Neoadjuvant Treatment

Rectal Cancer

China
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Improving Pregnancy Outcomes With Progesterone (IPOP)

HIV-1-infection | Pre-term Birth

Zambia
Lexicon Pharmaceuticals
Sanofi

Completed

Safety and Efficacy Study of Sotagliflozin on Glucose Control in Participants With Type 2 Diabetes, Moderate Impairment of Kidney Function, and Inadequate Blood Sugar Control (SOTA-CKD3)

Type 2 Diabetes Mellitus | Chronic Kidney Disease Stage 3

United States, Argentina, Brazil, Canada, Colombia, Germany, Hungary, Israel, Italy, Mexico, Poland, Romania, Russian Federation, South Africa, Spain, Ukraine
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Ethyl Icosapentate and Physical Activity in Treating Fatigue in Patients With Advanced Cancer

Fatigue | Advanced Malignant Neoplasm

United States

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