Search clinical trials for: In Vitro Kinase Inhibitor Assay

Total 9054 results

Pfizer

Recruiting

Evaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate to Severe Ulcerative Colitis

Ulcerative Colitis

United States, Israel, Poland, Canada, Japan, Belgium, Spain, Hungary, Finland, France, United Kingdom, Australia, Germany, Italy, Sweden, Netherlands, Slovakia
Pfizer

Completed

IDentification of Factors Predictive of Tofacitinib's Survival in Patient With Rheumatoid Arthritis

Arthritis, Rheumatoid

France
Pfizer

Completed

Efficacy And Safety Of Tofacitinib In Chinese Subjects With Active Psoriatic Arthritis

Psoriatic Arthritis

China
University Hospital, Montpellier

Completed

Resistance to Oral Therapy in Lung Cancer (RESTKI)

Non Small Cell Lung Cancer

France
University Hospital, Grenoble

Not yet recruiting

Quantiferon CMV to Identify Treatment Need For Asymptomatic CMV Infection After Solid Organ Transplant (QUANTIFOT) (QUANTIFOT)

Liver Transplantation | Kidney Transplantation | Heart Transplantation | Cytomegalovirus Infections | Lung Transplantation

France
Memorial Sloan Kettering Cancer Center

Completed

Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Rare Cancer

Sarcoma | Lymphoma | Kidney Cancer | Testicular Germ Cell Tumor | Head and Neck Cancer | Ovarian Cancer | Neuroblastoma | Retinoblastoma | Liver Cancer | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

United States
Pfizer

Terminated

Study to Evaluate PF-04965842 in Patients With Moderate to Severe Psoriasis

Plaque Psoriasis

United States, Canada
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb

Completed

Phase I Dasatinib/Erlotinib in Recurrent Non-small Cell Lung Cancer (NSCLC)

Non-Small-Cell Lung Carcinoma

United States
Pfizer

Recruiting

Korean Post-marketing Surveillance for Xeljanz XR (XRPMS)

Active Psoriatic Arthritis | Active Ankylosing Spondylitis | Active Moderate to Severe Rheumatoid Arthritis

Korea, Republic of
Centre Antoine Lacassagne
Institut National de la Santé Et de la Recherche Médicale, France

Completed

ELR+CXCL Cytokines in Metastatic Kidney Cancers: Predictive Markers of Resistance to Sunitinib (SUNITRES)

Metastatic Kidney Cancers

France
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Gene Therapy and Chemotherapy in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma

Lymphoma | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Pharmacokinetic Interaction Study Between Apatinib and Rosuvastatin or Metformin in Solid Tumor Subjects.

Solid Tumor, Adult

China
Emory University
National Cancer Institute (NCI)

Recruiting

MRX-2843 and Osimertinib for the Treatment of Advanced EGFR Mutant Non-small Cell Lung Cancer

Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Advanced Lung Non-Small Cell Carcinoma

United States
University of Wuerzburg
Pfizer

Completed

Sunitinib in Refractory Adrenocortical Carcinoma (SIRAC)

Adrenocortical Carcinoma

Germany
Pfizer

Completed

Study Of SU011248 Plus Gefitinib (Iressa) In Patients With Advanced Renal Cell Carcinoma

Carcinoma, Renal Cell

United States
University of Oxford
AstraZeneca

Completed

Olaparib +/- Cediranib or Chemotherapy in Patients With Platinum-resistant Ovarian Cancer (OCTOVA)

Ovarian Cancer

United Kingdom
H. Lee Moffitt Cancer Center and Research Institute
National Comprehensive Cancer Network

Withdrawn

Sorafenib and Bavituximab Plus SBRT in Unresectable Hepatocellular Carcinoma

Liver Cancer | HepatoCellular Carcinoma | Unresectable HepatoCellular Carcinoma

United States
Pfizer

Completed

A Study Of Combined C- MET Inhibitor And PAN-HER Inhibitor (PF-02341066 And PF-00299804) In Patients With Non- Small Cell Lung Cancer

Non Small Cell Lung Cancer

United States, Australia
Shanghai Zhongshan Hospital

Recruiting

Efficiency of Methotrexate and Tofacitinib in Mild and Moderate Patients

Takayasu Arteritis | Methotrexate | Inhibition | Treatment

China
Assistance Publique - Hôpitaux de Paris
Pfizer

Completed

Clinical Trial to Assess the Importance of Nephrectomy (CARMENA)

Metastatic Renal Cell Carcinoma

France
Fondazione IRCCS Istituto Nazionale dei Tumori,...

Terminated

Third Line TKI After 2 TKIs in Patients With mRCC (Tokio Study) (TOKIO)

Renal Cancer Cell

Italy
Memorial Sloan Kettering Cancer Center

Completed

A Phase I Study of Bevacizumab and Sunitinib in Metastatic Renal Cell Carcinoma Patients

Kidney Cancer | Metastatic Renal Cell Carcinoma

United States
OHSU Knight Cancer Institute
Genentech, Inc.; Oregon Health and Science University; American Association for... and other collaborators

Recruiting

Targeted Pathway Inhibition in Patients With Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Ductal Adenocarcinoma | Locally Advanced Pancreatic Ductal Adenocarcinoma | Unresectable Pancreatic Ductal Adenocarcinoma

United States
Yanfeng Hou

Recruiting

Efficacy Study of Iguratimod Combined With Tofacitab in Patients With RF Positive/Negative Rheumatoid Arthritis

Rheumatoid Arthritis | Therapy

China
Hoffmann-La Roche

Recruiting

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors

ALK Fusion-positive Solid or CNS Tumors

United States, Korea, Republic of, China, Spain, Canada, Australia, United Kingdom, Denmark, France, Italy, Germany
University of Texas Southwestern Medical Center
Pfizer

Recruiting

Tofacitinib in Recurrent GBM Patients

Glioblastoma

United States
Memorial Sloan Kettering Cancer Center
M.D. Anderson Cancer Center; Milton S. Hershey Medical Center; Stanford University and other collaborators

Active, not recruiting

Safety and Dose Finding Study of Neratinib in Children and Young Adults With Cancer That Has Returned or Not Responded to Treatment

Lymphoma | Leukemia | Solid Tumor | Central Nervous System Tumor

United States, Canada
Pfizer

Active, not recruiting

Real World Utilization and Outcomes With Dacomitinib First Line Treatment for EGFR Mutation-positive Advanced Non Small Cell Lung Cancer Among Asian Patients - A Multi Center Chart Review

Lung Cancer

Malaysia
National Cancer Institute (NCI)

Active, not recruiting

Ibrutinib in Treating Patients With Refractory Metastatic Cutaneous Melanoma

Metastatic Melanoma | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Recurrent Cutaneous Melanoma

United States
Hutchison Medipharma Limited

Recruiting

Clinical Study of HMPL-689 for Relapsed/Refractory Marginal Zone Lymphoma and Follicular Lymphoma

Follicular Lymphoma | Marginal Zone Lymphoma

China
H. Lee Moffitt Cancer Center and Research Institute
Incyte Corporation

Completed

A Sequential Two-Stage Dose Escalation Study to Evaluate the Safety and Efficacy of Ruxolitinib

Myelomonocytic Leukemia

United States
PIQUR Therapeutics AG
Royal Marsden NHS Foundation Trust; University College London Hospitals; Weill... and other collaborators

Completed

Open-Label, Non Randomized Phase 2 Study With Safety Run-In

Lymphoma, Malignant

United States, United Kingdom, Serbia, Bosnia and Herzegovina, France, Israel
Fundación Pública Andaluza para la gestión de la...

Active, not recruiting

Ixazomib in the Prophylaxis of Chronic Graft-versus-host Disease.

Multiple Myeloma | Hematopoietic Stem Cell Transplantation

Spain
Hoffmann-La Roche

Completed

Study of Oral RXDX-101 in Adult Patients With Locally Advanced or Metastatic Cancer Targeting NTRK1, NTRK2, NTRK3, ROS1, or ALK Molecular Alterations. (STARTRK-1)

Locally Advanced Solid Tumors | Metastatic Solid Tumors

United States, Korea, Republic of
GlaxoSmithKline

Completed

Phase I/II Study of Lapatinib in Combination With Paclitaxel as 1L Chemotherapy for ErbB2-positive MBC

Neoplasms, Breast

Japan
University of Rome Tor Vergata

Completed

Effect of SARS-CoV-2 Vaccination in Liver Transplant Recipients

Liver Transplantation | SARS-CoV-2 Vaccination

Italy
Novartis Pharmaceuticals

Not yet recruiting

Clinical Study of Asciminib in Previously Treated Indian Patients With Ph+ CML-CP Without T315I Mutation and in Patients With Ph+ CML-CP With T315I Mutation (ASC4INDIA)

Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase
Ascentage Pharma Group Inc.

Not yet recruiting

A Phase 3 Registrational Study of Olverembatinib (HQP1351) in Patients With CML (POLARIS-2)

Chronic Myeloid Leukemia | CML | CML, Chronic Phase

United States
Pfizer

Completed

Comparative Effectiveness Of Tumor Necrosis Factor Inhibitors And Tofacitinib Use In Earlier Lines Of Therapy And Use As Monotherapy.

Arthritis Rheumatoid

United States
Novartis Pharmaceuticals

Completed

Special Drug Use-results Surveillance of Scemblix Tablets

Chronic Myeloid Leukemia

Japan
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Vemurafenib With Sorafenib Tosylate or Crizotinib in Treating Patients With Advanced Malignancies With BRAF Mutations

Metastatic Malignant Neoplasm | Advanced Malignant Neoplasm | Recurrent Malignant Neoplasm | Refractory Malignant Neoplasm | BRAF Gene Mutation

United States
Institute of Biomedical Chemistry, Russia
Moscow Regional Research and Clinical Institute Moniki n.a. M.F. Vladimirskiy

Completed

Predicting the Response of Patients With Rheumatoid Arthritis to Treatment With Genetically Engineered Biological Drugs and Janus (JAK) Kinase Inhibitors

Rheumatoid Arthritis

Russian Federation
Oslo University Hospital

Terminated

Whole Brain Radiation With or Without Erlotinib for Brain Metastases From Non-Small Cell Lung Cancer (RadEr)

Cancer

Norway
Roswell Park Cancer Institute
National Cancer Institute (NCI); Boehringer Ingelheim; National Comprehensive...

Completed

Nintedanib and Capecitabine in Treating Patients With Refractory Metastatic Colorectal Cancer

Recurrent Colon Carcinoma | Recurrent Rectal Carcinoma | Rectal Adenocarcinoma | Colon Adenocarcinoma | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer

United States
Peking University Cancer Hospital & Institute

Not yet recruiting

Study to Evaluate the Efficacy and Safety of Immunotherapy With Axitinib in Advanced Collecting Duct Carcinoma

Collecting Duct Carcinoma

China
Mayo Clinic
National Cancer Institute (NCI)

Completed

Ruxolitinib Phosphate and Danazol in Treating Anemia in Patients With Myelofibrosis

Primary Myelofibrosis | Anemia | Secondary Myelofibrosis

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

T-cell Depleted Bone Marrow and G-CSF Stimulated Peripheral Stem Cell Transplantation From Related Donors in Treating Patients With Leukemia, Lymphoblastic Lymphoma, Myelodysplastic Syndrome, or Aplastic Anemia

Lymphoma | Myelodysplastic Syndromes | Leukemia | Myelodysplastic/Myeloproliferative Neoplasms

United States
Hospices Civils de Lyon

Unknown

MEK and Autophagy Inhibition in Metastatic/Locally Advanced, Unresectable Neuroblastoma RAS (NRAS) Melanoma (CHLOROTRAMMEL)

Metastatic NRAS Melanoma

France
Baylor Health Care System
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Metastatic Melanoma

Melanoma (Skin)

United States
University of Birmingham
Pfizer; AstraZeneca; Mirati Therapeutics Inc.; Cancer Research UK; Experimental Cancer...

Active, not recruiting

National Lung Matrix Trial: Multi-drug Phase II Trial in Non-Small Cell Lung Cancer

Adenocarcinoma | Carcinoma, Squamous Cell | Non-Small Cell Lung Cancer

United Kingdom

Search clinical trials for: In Vitro Kinase Inhibitor Assay

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