Search clinical trials for: Infliximab methotrexate (IFX MTX)

Total 422 results

Merck Sharp & Dohme LLC
Integrated Therapeutics Group

Completed

Remicade Study in Psoriatic Arthritis Patients Of Methotrexate-Naïve Disease (RESPOND) (Study P04422)

Arthritis, Psoriatic
Children's Hospital of Fudan University

Recruiting

Combined Immunosuppression for Pediatric Crohn's Disease

Crohn Disease | Immunosuppression | Children, Only | Infliximab

China
Children's Memorial Health Institute, Poland

Unknown

Efficacy and Safety of Two Regimens of Maintenance Therapy in Children With Crohn Disease

Crohn Disease

Poland
Helsinki University Central Hospital
Foundation for Paediatric Research, Finland; Päivikki and Sakari Sohlberg Foundation... and other collaborators

Completed

Aggressive Combination Drug Therapy in Very Early Polyarticular Juvenile Idiopathic Arthritis (ACUTE-JIA)

Juvenile Idiopathic Arthritis

Finland
Bristol-Myers Squibb

Completed

Abatacept and Infliximab in Combination With Methotrexate in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Spain, United States, Argentina, Brazil, Canada, Mexico, Peru, Korea, Republic of, Sweden, Australia, Russian Federation, Poland, Puerto Rico, Czech Republic, Denmark, South Africa, Switzerland
Centocor Ortho Biotech Services, L.L.C.
Schering-Plough

Completed

Trial Comparing Infliximab and Infliximab and Azathioprine in the Treatment of Patients With Crohn's Disease na�ve to Both Immunomodulators and Biologic Therapy (Study of Biologic and Immunomodulator Naive Patients in Chrohn's Disease: SONIC

Crohn Disease

United States, France, United Kingdom, Germany, Spain, Belgium, Israel, Greece, Canada, Netherlands, Austria, Norway, Denmark, Sweden, Portugal
Groupe d'Etude Therapeutique des Affections Inflammatoires...

Completed

Study Investigating Tailored Treatment With Infliximab for Active Crohn's Disease (TAILORIX)

Crohn's Disease

France
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

A Cohort Study Comparing IFX to CS for Moderate to Severe UC (INSURE)

Moderate to Severe Ulcerative Colitis

China
Chinese University of Hong Kong

Completed

Combination Methotrexate and Infliximab

Ankylosing Spondylitis
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety of ITX 5061 in Treatment-Naive Hepatitis C (HCV)-Infected Adults

Hepatitis C

United States, Puerto Rico
Shanghai Biomabs Pharmaceutical Co., Ltd.

Completed

CMAB008 With MTX Therapy in Adult Patients With Moderately to Severely Active Rheumatoid Arthritis

Rheumatoid Arthritis

China
Merck Sharp & Dohme LLC

Completed

A Trial of Anti-TNF Chimeric Monoclonal Antibody (cA2) in Korean Patients With Active Rheumatoid Arthritis Despite Methorexate (Extension Part)(Study P05645)(COMPLETED)

Arthritis, Rheumatoid
Rehab Werida

Completed

Infliximab and Adalimumab in Inflammatory Bowel Disease Patients.

Inflammatory Bowel Diseases

Egypt
Karolinska Institutet

Completed

Comparison of MTX+Anti-TNF to MTX+Conventional DMARDs in Patients With Early Rheumatoid Arthritis (RA) Who Failed MTX Alone (SWEFOT) (SWEFOT)

Rheumatoid Arthritis
Janssen Research & Development, LLC

Completed

A Study of the Effectiveness and Safety of Ustekinumab (STELARA) and CNTO 1959 Administered Under the Skin of Patients With Active Rheumatoid Arthritis, Despite Existing Methotrexate Therapy

Arthritis, Rheumatoid

Poland, Ukraine, Colombia, Bulgaria, United States, Singapore, Russian Federation, Argentina, Hungary, Chile, Czech Republic
Merck Sharp & Dohme LLC

Completed

A Placebo-Controlled, Double-Blinded, Randomized Trial of Remicade in Korean Patients With Rheumatoid Arthritis Despite Methotrexate (Study P04280)(COMPLETED)

Arthritis, Rheumatoid
UCB Pharma

Completed

A Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Certolizumab Pegol in Combination With Methotrexate in the Treatment of Disease Modifying Antirheumatic Drugs (DMARD)-naïve Adults With Early Active Rheumatoid Arthritis (C-early)

Rheumatoid Arthritis

Germany, United States, Argentina, Australia, Austria, Belgium, Canada, Colombia, Czechia, France, Hungary, Ireland, Italy, Mexico, Monaco, Netherlands, Poland, Romania, Spain, Sweden, Switzerland, United Kingdom
Schiano, Thomas D., MD
iTherX Pharmaceuticals Inc.

Terminated

Study of Hepatitis C Virus (HCV) Entry Inhibitor in Liver Transplant Recipients With HCV Infection

Hepatitis C Infection

United States
Chugai Pharma Taiwan

Completed

Study of Tocilizumab in Combination With Methotrexate for Treatment of Moderate to Severe Rheumatoid Arthritis Patients

Rheumatoid Arthritis (RA)

Taiwan
RemeGen Co., Ltd.

Terminated

A Study of the Efficacy and Safety of TACI-antibody Fusion Protein Injection (RC18) in Subjects With Inadequate Response to TNF-α Antagonists Due to Treat Moderate and Severe Rheumatoid Arthritis

Moderate and Severe Rheumatoid Arthritis

China
RemeGen Co., Ltd.

Completed

A Study of the Efficacy and Safety of TACI-antibody Fusion Protein Injection (RC18) in Subjects With Inadequate Response to MTX Due to Treat Moderate and Severe Rheumatoid Arthritis.

Moderate and Severe RheumatoId Arthritis

China
Merck Sharp & Dohme LLC

Terminated

Efficacy & Safety of Infliximab Monotherapy Vs Combination Therapy Vs AZA Monotherapy in Ulcerative Colitis (Part 1) Maintenance Vs Intermittent Therapy for Maintaining Remission (Part 2)(Study P04807)

Ulcerative Colitis
University of Birmingham
National Institute for Health Research, United Kingdom; University Hospital...

Completed

Pilot Study of Hepatitis C Virus Entry Inhibitor (ITX 5061) in Liver Transplant Recipients (ITX5061)

Hepatitis C | Evidence of Liver Transplantation

United Kingdom
Université Catholique de Louvain

Completed

A Comparison of Methotrexate Alone or Combined to Infliximab or to Pulse Methylprednisolone in Early Rheumatoid Arthritis: A Magnetic Resonance Imaging Study

Rheumatoid Arthritis

Belgium
Association de Recherche Clinique en Rhumatologie

Completed

Study of Two Schedules of Infliximab Maintenance Therapy in Ankylosing Spondylitis

Ankylosing Spondylitis

France
Geistlich Pharma AG

Withdrawn

AMIC vs. MFx in the Ankle (AMARTA)

Chondral Defect | Osteochondral Lesion of Talus | Microfracture

United Kingdom
Antares Pharma Inc.

Completed

Exposure Study Comparing 3 Routes of Methotrexate (MTX) Administration

Rheumatoid Arthritis

United States
Merck Sharp & Dohme LLC

Terminated

Dose Optimization of Infliximab in Moderate to Severe Plaque Psoriasis (Study P05315) (DOSE)

Psoriasis
University Hospital, Rouen

Completed

Gene Expression Profiling in PBMCs as a Tool for Prediction of Infliximab Responsiveness in Rheumatoid Arthritis

Rheumatoid Arthritis

France
Merck Sharp & Dohme LLC

Completed

The Effects of Infliximab Versus Methotrexate in the Treatment of Moderate to Severe Psoriasis (Study P04271AM2)(COMPLETED)

Psoriasis
Genor Biopharma Co., Ltd.

Unknown

Clinical Comparative Study to Evaluate the Efficacy and Safety of Recombinant Anti-TNF-alpha Antibodies for Injection

Rheumatoid Arthritis

China
Fen Li

Unknown

Predictability Studies on the Efficacy of TNF-α Inhibitors in Chinese RA From "Real World"

Rheumatoid Arthritis
Chinese University of Hong Kong

Completed

The Chinese University of Hong Kong Early Arthritis Study (ERA)

Rheumatoid Arthritis

China
Women's Hospital School Of Medicine Zhejiang University
Qilu Hospital of Shandong University; Huazhong University of Science and Technology and other collaborators

Recruiting

Combination of Methotrexate(MTX) and Actinomycin(ACTD) in the Low Risk Gestational Trophoblastic Neoplasma （GTN） Patients With Score of 5-6

Gestational Trophoblastic Tumor | Effects of Chemotherapy | Drug Toxicity

China
Stanford University

Completed

Regorafenib and Methotrexate in Treating Participants With Recurrent or Metastatic KRAS Mutated Non-Small Cell Lung Cancer

Recurrent Non-Small Cell Lung Carcinoma | KRAS Gene Mutation | Metastatic Malignant Neoplasm in the Brain | Stage IV Non-Small Cell Lung Cancer AJCC v7

United States
University of Cincinnati

Unknown

Use of Immunosuppressive Therapy for Sarcoidosis

Sarcoidosis

United States
Chelsea Therapeutics

Completed

A Study to Assess CH1504 in Patients With Active Rheumatoid Arthritis (CH-1504-201)

Arthritis, Rheumatoid

Canada
Groupe d'Etude Therapeutique des Affections Inflammatoires...
Celltrion

Recruiting

Management of Moderate POstoperative Recurrence in Crohn's Disease: a randoMizEd contROLled Trial of Therapeutic Escalation, the POMEROL Trial. (POMEROL) (POMEROL)

Crohn Disease

France
Janssen Korea, Ltd., Korea

Completed

An Observational Study of Infliximab Injection in Ankylosing Spondylitis, Rheumatoid Arthritis, Psoriatic Arthritis and Psoriasis Participants

Arthritis, Rheumatoid | Psoriasis | Arthritis, Psoriatic | Spondylitis, Ankylosing
University of Sao Paulo General Hospital
Hospital Santa Marcelina

Recruiting

Treatment of Patients With Mild Coronavirus-19 (COVID-19) Disease With Methotrexate Associated to LDL Like Nanoparticles (Nano-COVID19) (Nano-COVID19)

Inflammation | Covid19 | Coronavirus

Brazil
Memorial Sloan Kettering Cancer Center
Pharmacyclics LLC.; Janssen Biotech, Inc.

Recruiting

Bruton's Tyrosine Kinase (BTK) Inhibitor, Ibrutinib, in Patients With Newly Diagnosed or Refractory/Recurrent Primary Central Nervous System Lymphoma (PCNSL) and Refractory/Recurrent Secondary Central Nervous System Lymphoma (SCNSL)

Adult Patients With Newly Diagnosed or Relapsed or Refractory Primary Central Nervous System Lymphoma (PCNSL) | Or Relapsed or Refractory Secondary Central Nervous System Lymphoma (SCNSL)

United States
Sixth Affiliated Hospital, Sun Yat-sen University

Not yet recruiting

N-3 Polyunsaturated Fatty Acids Prevent Postoperative Recurrence of Crohn's Disease

Inflammatory Bowel Diseases | Crohn Disease | Polyunsaturated Acid Lipidosis
Fudan University

Terminated

Study on VCD/IE in the Patients With Ewing's Sarcoma Family of Tumors (ESFT)

Ewing's Sarcoma

China
UCB Pharma SA
Parexel

Completed

Study to Assess the Short- and Long-term Efficacy of Certolizumab Pegol Plus Methotrexate Compared to Adalimumab Plus Methotrexate in Subjects With Moderate to Severe Rheumatoid Arthritis (RA) Inadequately Responding to Methotrexate

Rheumatoid Arthritis

Romania, United States, Australia, Austria, Bulgaria, Canada, Czechia, France, Germany, Greece, Hungary, Ireland, Italy, Mexico, Monaco, Poland, Portugal, Spain, Switzerland, United Kingdom
IGF Oncology, LLC

Terminated

IGF-MTX Conjugate in the Treatment of Myelodysplastic Syndrome

Myelodysplastic Syndromes | Leukemia, Myelomonocytic, Chronic | Anemia, Refractory, With Excess of Blasts

United States
Centocor, Inc.
Centocor BV

Completed

An Efficacy and Safety Study of CNTO 148 Subcutaneous Injection Compared With Placebo in Patients With Active Rheumatoid Arthritis

Rheumatoid Arthritis
Centre de Recherche Médicale de Lambaréné
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); Institute...

Recruiting

Treatment of Tuberculosis Multidrug Resistance Treatment of Tuberculosis Multidrug Resistance (TB-MR)

Multi-drug Resistant Tuberculosis

Gabon
Groupe d'Etude Therapeutique des Affections Inflammatoires...
Saint-Louis Hospital, Paris, France

Completed

A proSpective Randomized Controlled Trial comParing infliximAb-antimetabolites Combination Therapy to Anti-metabolites monotheRapy and Infliximab monothErapy in Crohn's Disease Patients in Sustained Steroid-free Remission on Combination Therapy (SPARE)

Crohn's Disease

Australia, Belgium, France
Shanghai Henlius Biotech

Completed

Study of Safety and Efficacy of HLX01+MTX in Patients With Rheumatoid Arthritis

Moderately to Severely Active Rheumatoid Arthritis

China
Chugai Pharma Taiwan

Completed

Extension Study of Tocilizumab Long Term Treatment of Moderate to Severe Rheumatoid Arthritis Patients

Rheumatoid Arthritis

Taiwan

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