Search clinical trials for: Intramuscular (IM) naloxone

Total 1080 results

The University of Texas Health Science Center,...
Zoll Medical Corporation; Vivian L. Smith Foundation for Neurologic Research

Terminated

To Study the Effect of Early Cooling in Acute Subdural Hematoma Patients (HOPES)

Subdural Hematoma, Traumatic

United States, Japan
Tianjin Chest Hospital

Unknown

Virtual Histology Intravascular Ultrasound to Evaluate Prognostic Risks of Saphenous Vein Graft Disease Before Percutaneous Coronary Intervention.

Percutaneous Coronary Intervention | Saphenous Vein Graft Disease | Major Adverse Cardiovascular Events | Virtual Histology Intravascular Ultrasound

China
Brainstorm-Cell Therapeutics
Hadassah Medical Organization

Completed

Autologous Cultured Mesenchymal Bone Marrow Stromal Cells Secreting Neurotrophic Factors (MSC-NTF), in ALS Patients.

Amyotrophic Lateral Sclerosis

Israel
The Medicines Company
The Cleveland Clinic

Completed

MDCO-216 Infusions Leading to Changes in Atherosclerosis: A Novel Therapy in Development to Improve Cardiovascular Outcomes - Proof of Concept Intravascular Ultrasound (IVUS), Lipids, and Other Surrogate Biomarkers Trial (PILOT)

Acute Coronary Syndrome

Poland, Netherlands, Hungary, Canada, Czechia
Memorial Medical Center
U.S. Army Medical Research and Development Command; Henry M. Jackson Foundation...

Terminated

Study of the Effect of Regional Nerve Blocks on Pain and Inflammation After Video Assisted Thorascopic Lung Surgery (VATS_IM)

Pain

United States
University of Alabama at Birmingham
Hospital for Special Surgery, New York

Completed

BLYS and IFN in SLE

Systemic Lupus Erythematosus

United States
Kasr El Aini Hospital

Active, not recruiting

Biologic Therapy in Pediatric JIA Uveitis

Juvenile Idiopathic Arthritis Associated Uveitis

Egypt
VA Office of Research and Development

Recruiting

A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder (VA-BRAVE)

Opioid Use Disorder

United States
University of California, Irvine

Recruiting

Effect of Ultra-low Dose Naloxone on Remifentanil-Induced Hyperalgesia

Hyperalgesia

United States
Purdue Pharma LP

Completed

A Study of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain

Low Back Pain

United States
Mundipharma Research GmbH & Co KG

Completed

A Study to Demonstrate the Analgesic Efficacy of Oxycodone/Naloxone Prolonged Release Tablets in Addition to Pregabalin Compared to Pregabalin Alone in Opioid-naïve Subjects Treated With Pregabalin Suffering From Moderate to Severe Pain Due to Diabetic Polyneuropathy

Moderate to Severe Pain Due to Diabetic Polyneuropathy

Germany
Riphah International University

Recruiting

Comparison of IMES Versus DN on ATrPs of AC

Shoulder Pain

Pakistan
University of North Carolina, Chapel Hill
National Institute on Drug Abuse (NIDA)

Completed

Nalox-Comm: Naloxone Communication Training for Pharmacists (Nalox-Comm)

Naloxone

United States
University of Washington
U.S. National Science Foundation

Completed

Naloxone Auto-injection in Healthy Volunteers

Overdose Antidote

United States
Nanjing First Hospital, Nanjing Medical University
Shanxi Provincial People's Hospital

Enrolling by invitation

IVI-guided Versus Angiography-guided PCI in Patients With Diabetes Mellitus (IVI-DIABETES)

Diabetes

China
ZOLL Circulation, Inc., USA

Completed

COOL AMI EU Pivotal Trial to Assess Cooling as an Adjunctive Therapy to PCI In Patients With Acute MI (Phase A)

Acute Myocardial Infarction

Slovenia
University Hospital, Motol
professor Josef Veselka; associate professor Petr Hájek; Martin Horváth

Completed

Long-term Follow-up NIRS-IVUS Imaging of Pre-existing Carotid Stents

Carotid Atherosclerosis | Restenosis | Carotid Artery Stenting | Near Infrared Spectroscopy | Atherosclerotic Plaque

Czechia
Brigham and Women's Hospital
EMD Serono

Completed

Comparison of Crinone 8% Intravaginal Gel and IM Progesterone Supplementation for In Vitro Fertilization (IVF)

Infertility

United States
Washington University School of Medicine
Incyte Corporation; PapiVax Biotech, Inc.

Recruiting

Neoantigen-based Personalized DNA Vaccine With Retifanlimab PD-1 Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma

Unmethylated Glioblastoma

United States
Craig L Slingluff, Jr
GlaxoSmithKline

Completed

Study to Assess Safety and Immune Response of Stage IIB-IV Resected Melanoma After Treatment With MAGE-A3 ASCI (Mel55)

Melanoma

United States
University of Maryland, Baltimore

Withdrawn

TLR-9 Adjuvanted Vaccination for Chronic Hepatitis B (BOOST-9)

Hepatitis B

United States
Alvotech Swiss AG

Completed

PK, Safety and Tolerability Study of AVT02 (Adalimumab) Pre-filled Syringe (PFS) vs, AVT02 Autoinjector (AI)

Phase 1

New Zealand
University of Maryland, Baltimore

Completed

Hepatitis B Vaccine in Seniors

Hepatitis B Vaccination

United States
AbbVie (prior sponsor, Abbott)

Completed

A Study to Evaluate the Impact of Adalimumab on Quality of Life, Health Care Utilization and Costs of Ulcerative Colitis Subjects in the Usual Clinical Practice Setting (InspirAda)

Ulcerative Colitis
Hospital Universitari Vall d'Hebron Research Institute

Completed

Intravitreal Adalimumab in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration

Age-Related Macular Degeneration | Choroidal Neovascularization

Spain
Abbott

Approved for marketing

Early Access Program of the Safety of Human Anti-TNF Monoclonal Antibody Adalimumab in Subjects With Active Rheumatoid Arthritis (ReAct)

Rheumatoid Arthritis
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Recruiting

Assessing a Clinically-meaningful Opioid Withdrawal Phenotype

Opioid Use Disorder | Opioid Withdrawal | Opioid Craving

United States
Virginia Commonwealth University
National Institute on Drug Abuse (NIDA)

Completed

Drug-drug Interaction Study of Lemborexant as an Adjunctive Treatment for Buprenorphine/Naloxone for Opioid Use Disorder

Drug Interaction | Analgesics, Opioid

United States
Ullevaal University Hospital
University of Oslo

Terminated

Reversal of Ketamine Pharmacodynamic Effects With Naloxone

Pain

Norway
AbbVie

Completed

Study to Investigate Efficacy and Safety of Adalimumab in Japanese Subjects With Generalized Pustular Psoriasis (GPP)

Generalized Pustular Psoriasis (GPP) | Adalimumab | Japanese
University of Alabama at Birmingham
Merck Sharp & Dohme LLC; University of Washington; Wits Reproductive Health and...

Active, not recruiting

Evaluation of Pharmacokinetic Drug-drug Interactions Between Hormonal Contraceptives and Doravirine-containing ART Among Women Living With HIV in South Africa (EPIC)

HIV Infections | Contraception | Drug-drug Interaction

South Africa
Mundipharma Korea Ltd

Completed

A Study to Evaluate Efficacy and Safety of Oxycodone/Naloxone Compared to OxyContin in Korean Cancer Patients (TOP)

Cancer

Korea, Republic of
University Hospital Inselspital, Berne

Completed

Early Postoperative Administration of Oxycodone +/- Naloxone and Duration of Epidural Analgesia

Epidural Analgesia | Radical Cystectomy | Postoperative Pain Management | Oral Oxycodone With/Without Naloxone | Return of the Bowel Function

Switzerland
Medical University of Vienna

Completed

Oral Oxycodone After Major Cardiac Surgery

Heart; Dysfunction Postoperative, Cardiac Surgery

Austria
Mundipharma Oy

Completed

OXN PR Compared to OXY PR in Subjects With Postoperative Pain After Knee Arthroplasty (OXN4505)

Post Operative Pain

Finland
Tanta University

Completed

Effect of Intrathecal Naloxone in the Incidence of Pruritis After C.S

Pruritis

Egypt
Centre for Addiction and Mental Health
Academic Health Science Centres

Completed

Feasibility Study of Oral Naloxone for Treatment of Methadone-induced Constipation

Constipation

Canada
NuPulseCV

Unknown

Feasibility Study of the Intravascular Ventricular Assist System (iVAS)

Heart Failure NYHA Class III | Heart Failure NYHA Class IV

United States
Centers for Disease Control and Prevention
Ministry of Health, Thailand

Unknown

Immunogenicity of Influenza Vaccines in HIV-infected Persons in Thailand

Influenza

Thailand
Albert Einstein College of Medicine
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Active, not recruiting

Novel Approach for the Prevention of Hypoglycemia Associated Autonomic Failure (HAAF)

Hypoglycemia | Diabetes Mellitus, Type 1 | Hypoglycemia Unawareness

United States
Janssen-Cilag A.G., Switzerland

Completed

Comparison of Two Dosage Strengths of Transdermal Fentanyl Versus Transdermal Buprenorphine and Placebo in Acute Pain Models in Healthy Volunteers.

Pain
Infraredx

Completed

An Observational Study of Cholesterol in Coronary Arteries (COLOR)

Myocardial Infarction | Myocardial Ischemia | Coronary Artery Disease | Angina

United States
Abbott

Completed

Efficacy and Safety of Adalimumab in Adult Chinese Subjects With Active Ankylosing Spondylitis

Ankylosing Spondylitis

China
Stanford University
National Institute on Drug Abuse (NIDA)

Completed

5HT3 Antagonists to Treat Opioid Withdrawal and to Prevent the Progression of Physical Dependence

Opioid Withdrawal | Physical Dependence

United States
Artoss Inc.

Active, not recruiting

Artoss Foot and Ankle Surgery Registry (ARK)

Trauma Injury | Deformity; Bone | Arthritis Foot

United States
Artoss Inc.

Active, not recruiting

Artoss Prospective Spine Registry Outcomes (ASTRO)

Spinal Fusion

United States
Ajou University School of Medicine

Terminated

Fractional Flow Reserve (FFR) Versus Intravascular Ultrasound (IVUS) in Intermediate Coronary Artery Disease (FAVOR)

Coronary Artery Stenosis

Korea, Republic of
TC Erciyes University

Completed

Impact of Active Heating on Maternal and Neonatal Well-being

Hypothermia

Turkey
Medipol University

Completed

Effectiveness of Chiropractic Application for Acute Low Back Pain

Low Back Pain, Mechanical

Turkey
Fluart Innovative Vaccine Ltd, Hungary

Completed

Immunogenicity and Tolerability Study of Fluval AB Novo Suspension for Injection for Children and Adolescents

Human Influenza

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