Search clinical trials for: Intravenous (IV) single dose

Total 1129 results

Emerald Health Pharmaceuticals

Completed

To Evaluate the Safety and Tolerability, Pharmacokinetics, Food-effect and Pharmacodynamics of EHP-101 in Healthy Volunteers

Healthy

Australia
J2H Biotech

Completed

Phase 1 Study to Investigate Safety, Tolerability, PK/PK of J2H-1702 in Healthy Males

Non-alcoholic Steatohepatitis

Korea, Republic of
Radboud University Medical Center

Completed

Anidulafungin Pharmacokinetics Given as a Single Intravenous Dose to Obese Patients (ADOPT) (ADOPT)

Obesity Morbid

Netherlands
Instituto de Investigación Sanitaria de la Fundación...
Effice Servicios Para la Investigacion S.L.

Active, not recruiting

Clinical Trial to Evaluate Safety and Efficacy of Cell Therapy in Patients With Cicatricial Conjuntivitis. (CELOPHIN)

Stevens-Johnson Syndrome | Lyell Syndrome | Pemphigoid | Chronic Conjunctivitis

Spain
Respivert Ltd

Completed

A Study to Investigate the Safety and Tolerability of a New Inhaled Formulation of RV568 in Healthy Volunteers

Healthy Volunteers | COPD

United Kingdom
C2N Diagnostics

Completed

Safety, Tolerability, and Pharmacokinetics of C2N-8E12 in Subjects With Progressive Supranuclear Palsy

Progressive Supranuclear Palsy

United States
Jair Bar, M.D., Ph.D.
Merck Sharp & Dohme LLC

Completed

Anti PD-1 Neo-adjuvant Treatment for NSCLC (MK3475-223)

Non Small Cell Lung Carcinoma | Stage II | Stage I

Israel
Novartis Pharmaceuticals

Completed

Study of Diagnostic Performance of [18F]CTT1057 for PSMA-positive Tumors Detection (GuideView)

Prostatic Neoplasms | Prostate Cancer

Spain, Italy, France, Switzerland, United States
Knopp Biosciences
Biogen

Completed

Dexpramipexole Japanese PK Study

Amyotrophic Lateral Sclerosis

United Kingdom
Human Genome Sciences Inc.
GlaxoSmithKline

Completed

Study of Belimumab Administered Subcutaneously to Healthy Subjects

Healthy

United States
GlaxoSmithKline

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of GSK2586184 and the Effect of Food and Gender (JAK116439)

Systemic Lupus Erythematosus

Belgium
Beijing Tongren Hospital

Recruiting

Human Placental Mesenchymal Stem Cells Treatment on Diabetic Foot Ulcer

Diabetic Foot Ulcer

China
Autoimmune Technologies, LLC

Completed

Safety Study of Flufirvitide-3 Nasal Spray in Healthy Subjects

Influenza

United States
Masaryk Memorial Cancer Institute

Recruiting

Optimization of Fractionation Schedules of Heel Spur Radiotherapy Prospective Randomized Open-label Trial

Heel Spur

Czechia
Arthrosi Therapeutics
Iqvia Pty Ltd

Completed

Pharmacokinetic Study of AR882 in Subjects With Various Degrees of Renal Impairment

Renal Impairment

United States, New Zealand
Abivax S.A.

Completed

Food Effect on Pharmacokinetic Parameters of ABX464

Healthy Volunteers

Mauritius
Melinta Therapeutics, Inc.

Completed

Open Label Study Evaluating the Effects of a Single Oritavancin Infusion on Cytochrome P450 in Healthy Volunteers (DDI)

Healthy

United States
Medicines for Malaria Venture
Cross Research S.A.

Completed

Safety Tolerability & Pharmacokinetics of Co-administered Single Doses of OZ439 & Piperaquine to Healthy Subjects

Healthy

Switzerland
Vigonvita Life Sciences
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Recruiting

a Study to Evaluate the Pharmacokinetics and Safety of TPN171H Tablets in Patients With Renal Insufficiency and Healthy Subjects

Erectile Dysfunction | Pulmonary Arterial Hypertension

China
Galapagos NV

Completed

Pharmacokinetics of GLPG3067 in Male Subjects With Cystic Fibrosis.

Cystic Fibrosis

Belgium
PhaseBio Pharmaceuticals Inc.

Completed

Pharmacokinetic Profile of Two Formulations of PB1023 Following Single Subcutaneous Injection in Subjects With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
Curacle Co., Ltd.
KCRN Research, LLC

Completed

First-In-Human Study of CU06-1004 Following Single and Multiple Ascending Doses in Healthy Volunteers

Diabetic Macular Edema

United States
Prometheus Biosciences, Inc., a subsidiary of Merck...
Altasciences Company Inc.

Completed

Bioavailability of SC Formulation and Japanese Ethnobridging Study for PRA023

Healthy

United States
Galapagos NV

Completed

Pharmacokinetics of GLPG2737 in Male Subjects With Cystic Fibrosis

Cystic Fibrosis

Belgium
Yuhan Corporation

Completed

Safety/Tolerability and Pharmacokinetics/Pharmacodynamics of YH4808 After Oral Administration in Healthy Male Subjects

Healthy

Korea, Republic of
Respivert Ltd

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of RV1729

Asthma | Healthy Volunteers

United Kingdom
Kind Pharmaceuticals LLC

Completed

A Dose-escalation Study of AND017 in Healthy Subjects

Healthy Volunteers

Australia
Nutrition Institute, Slovenia
Vizera d.o.o.; ADM, Ambulanta družinske medicine, Ljubljana, Slovenia; Adrialab... and other collaborators

Completed

Comparative Single-dose Bioavailability Study of Different CoQ10 Formulations

Bioavailability of Coenzyme Q10

Slovenia
GangaGen, Inc.

Completed

Safety & Efficacy of an Antibacterial Protein Molecule Applied Topically to the Nostrils of Volunteers and Patients

Bacterial Infections | Infectious Disease

Singapore
Estetra

Completed

Safety, Tolerability and Pharmacokinetics of Estetrol (E4) After Single and Multiple Oral Doses in Healthy Female Volunteers

Menopause | Contraception

Bulgaria
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Safety, Tolerability and Effects of Single and Multiple Ascending Doses of ASP1707 in Healthy Male and Pre-menopausal Female Subjects, Including a Comparison of the Effects Under Fasted and Fed Conditions in Healthy Young Male Subjects

Pharmacokinetics of ASP1707 | Pharmacodynamics of ASP1707

France
GlaxoSmithKline

Completed

Safety Study of GSK1995057 Given as Single and Repeat Intravenous Doses in Healthy Subjects.

Respiratory Disorders

United Kingdom
Menarini Group

Completed

Oral Treatment for Gynaecological Post-operative Pain With Dexketoprofen Trometamol and Tramadol Hydrochloride (DAVID lap)

Acute Pain

Romania, Poland, Hungary, Latvia, Lithuania, Russian Federation, Slovakia, Spain
Dartmouth-Hitchcock Medical Center

Completed

Neuraceq™ PET for Detection of Brain Changes in Young Athletes Post-concussion

Concussion, Brain

United States
Guangzhou Henovcom Bioscience Co. Ltd.

Completed

A Study of HNC664 in Healthy Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetics

Healthy

United States
Amsterdam UMC, location VUmc
Dutch Cancer Society

Recruiting

Single-dose Preoperative Partial Breast Irradiation in Low-risk Breast Cancer Patients (ABLATIVE-2)

Breast Cancer

Netherlands
Fundacao Champalimaud

Unknown

Single Dose Radiotherapy (SDRT) in Oligometatstasis Ablation (OLIGO)

Metastatic Cancer

Portugal
UMC Utrecht

Completed

Single Dose Ablative Radiation Treatment for Early-Stage Breast Cancer (ABLATIVE)

Breast Neoplasm

Netherlands
Galapagos NV
Pharmaceutical Research Associates; SGS S.A.

Completed

A Study to Assess Safety, Tolerability and Pharmacokinetics of GLPG2451 in Healthy Female Subjects

Healthy

Belgium
Menarini Group

Completed

Oral Treatment for Orthopaedic Post-operative Pain With Dexketoprofen Trometamol and Tramadol Hydrochloride (DAVID-art)

Acute Pain

Serbia, Latvia, Spain, Hungary, Lithuania, Poland, Taiwan, Czech Republic, Germany, Ukraine
PHARMENTERPRISES LLC

Completed

Double-blind, Randomized, Placebo-controlled Study of the Safety, Tolerability and Pharmacokinetics of Ascending Doses of XC243 After Single and Multiple Oral Administration in Healthy Volunteers.

Healthy Volunteers

Russian Federation
GlaxoSmithKline

Completed

Phase I Study of GW856553 (Losmapimod)

Acute Coronary Syndrome

Australia
Gilead Sciences

Completed

A Study Evaluating GS-9620 in Virologically Suppressed Subjects With Chronic Hepatitis B Virus Infection

Hepatitis B

Korea, Republic of, United States, Canada, Australia, New Zealand
Dairy A Day, Inc.

Completed

"Fermented Dairy Beverage on Inflammation/Immune Function in Stressful Exercise" (DAD)

Healthy Subjects

United States
Vanderbilt University
Vanderbilt University Medical Center

Completed

Putative Cognitive Enhancer VU319

Cognitive Impairment

United States
Stanford University
Washington University School of Medicine; Duke University; University of Washington and other collaborators

Enrolling by invitation

Antibiotic Prophylaxis in Rhinoplasty

Nasal Obstruction | Nasal Surgical Procedures

United States
Imperial College London
Cambridge University Hospitals NHS Foundation Trust; University of Manchester; Food Standards Agency, United Kingdom

Completed

Mechanisms Underlying Peanut Allergic Reactions in TRACE Peanut Study Participants: Extension Study (TRACEextension)

Food Hypersensitivity | Peanut Hypersensitivity
Pfizer

Completed

Study in Healthy Adults Evaluating PF-07202954

Liver Fibrosis | Non-Alcoholic Fatty Liver Disease

United States
Chiesi Farmaceutici S.p.A.

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Inhaled CHF6001 (CHF6001Ext)

Chronic Obstructive Pulmonary Disease

United Kingdom
First Affiliated Hospital Xi'an Jiaotong University
Eureka Therapeutics Inc.

Unknown

ET190L1-ARTEMIS™ T Cells in Relapsed, Refractory B Cell Leukemia and Lymphoma

CD19+ Lymphoma, B-Cell | CD19+ Leukemia, B-Cell

China

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