Search clinical trials for: Intravitreal aflibercept injection

Total 10306 results

Geisinger Clinic

Terminated

Effect of Subcutaneous Semaglutide on Kidney Transplant Candidacy (RAISE-KT)

Obesity | Diabetic Kidney Disease | Type 2 Diabetes Mellitus in Obese | CKD | Severe Obesity

United States
Dongyang People's Hospital

Recruiting

Manage Macular Cystoid Edema With Retinal Vein Obstruction Using Traditional Chinese Medicine and Ranibizumab (JQMMT+RA)

Macular Cystoid Edema

China
Novartis Pharmaceuticals

Completed

Study to Assess the Efficacy and Safety of Brolucizumab 6mg Compared to Aflibercept 2 mg in a Treat-to-control Regimen (TALON) (TALON)

Age-related Macular Degeneration

United States, Austria, Czechia, Italy, Taiwan, Belgium, Germany, Australia, Israel, Canada, France, Spain, Korea, Republic of, United Kingdom, Portugal, Netherlands, Sweden, Argentina, Malaysia, Switzerland
Bayer
Regeneron Pharmaceuticals

Active, not recruiting

Extension Study to Evaluate the Long-term Outcomes of Subjects in Study 20090 (FIREFLEYE next)

Retinopathy of Prematurity (ROP)

Spain, Korea, Republic of, Singapore, Malaysia, Japan, Taiwan, Bulgaria, Italy, Argentina, Czechia, Greece, Israel, Netherlands, Portugal, Romania, Russian Federation, Slovakia, Sweden, Turkey, United Kingdom, Ukraine, Hungary, Belgium and more
Northern California Retina Vitreous Associates
Regeneron Pharmaceuticals

Completed

The Endurance 1 Trial (Endurance)

Diabetic Macular Edema
Arshad Khanani
Genentech, Inc.

Completed

Evaluation of Pain and Inflammation After Injection of Lucentis vs Eylea for Treatment of Wet Macular Degeneration

Neovascular Age-Related Macular Degeneration

United States
University Hospital, Basel, Switzerland

Completed

Study Comparing Ranibizumab Monotherapy With Combined Verteporfin Therapy in Subfoveal CNV

Age-Related Macular Degeneration | Choroidal Neovascularization

Switzerland
Beijing Hospital

Completed

Combination of Intravitreal Ranibizumab With or Without Micropulse Laser for the Treatment of DME

Diabetic Macular Edema

China
Bayer

Completed

A Study to Learn How Safe the Study Drug Intravitreal (Given by an Injection Into the Eye) Aflibercept is in Participants in India With Diabetic Macular Edema (VISION-AF)

Diabetic Macular Edema

India
The Emmes Company, LLC
National Eye Institute (NEI); University of Wisconsin, Madison; Milton S. Hershey...

Completed

Study of Comparative Treatments for Retinal Vein Occlusion 2 (SCORE2) (SCORE2)

Central Retinal Vein Occlusion

United States
University Hospital Inselspital, Berne

Terminated

Comparison of VA Guided Versus OCT Guided TER Using Aflibercept for Diabetic Macular Edema (AVOCT Study) (AVOCT)

Diabetic Macular Edema

Switzerland
Asociación para Evitar la Ceguera en México

Unknown

Bevacizumab and Photodynamic Therapy in Neovascular Age Related Macular Degeneration

Age Related Macular Degeneration

Mexico
Retina-Vitreous Associates Medical Group

Completed

Long-Term Efficacy and Safety of Aflibercept Intravitreal Injections for the Treatment of Diabetic Macular Edema (Endurance3)

Clinically Significant Diabetic Macular Edema
Southeast Retina Center, Georgia

Completed

IAI for Persistent DME After Treatment With Bevacizumab And Ranibizumab (ROTATED)

Diabetic Macular Edema

United States
Centre Oscar Lambret
Sanofi

Terminated

Aflibercept and Chemotherapy as First Line Treatment for Metastatic Colorectal Cancer Assessable With DCE-US (PULSAR). (PULSAR)

Metastatic Colorectal Cancer

France
Novartis Pharmaceuticals

Completed

Systemic Vascular Endothelial Growth Factor (VEGF) Protein Dynamics Following Intravitreal Injections of Ranibizumab Versus Aflibercept in Patients With Neovascular Age-related Macular Degeneration (TIDE AMD)

Wet Age-Related Macular Degeneration

Germany
Arshad Khanani
Genentech, Inc.

Completed

Evaluation of Inflammation and Pain Post Injection of Ranibizumab vs Aflibercept in Patients With DME

Diabetic Macular Edema

United States
Bayer
Regeneron Pharmaceuticals

Completed

Efficacy and Safety of VEGF Trap Eye in Diabetic Macular Edema (DME) With Central Involvement (VIVID EAST)

Macular Edema

China, Hong Kong, Korea, Republic of, Russian Federation
Roxall Medizin

Completed

Efficacy and Safety of Specific Immunotherapy With CLUSTOID Grass Pollen

Allergic Rhinitis

Germany
Cairo University

Terminated

Effect of Ranibizumab Versus Bevacizumab on the Macular Perfusion in Diabetic Macular Edema (REBEL)

Diabetic Retinopathy | Diabetic Macular Edema | Vascular Endothelial Growth Factor Overexpression | Macular Ischemia

Egypt
University of Malaya

Unknown

Effect of Intravitreal Anti-VEGF on Retinal Vessels Diameter

Age Related Macular Degeneration

Malaysia
Novartis Pharmaceuticals

Completed

A Comparison of Ranibizumab and Aflibercept for the Development of Geographic Atrophy in (Wet) AMD Patients (RIVAL)

Age-Related Macular Degeneration

Australia
National Cancer Institute (NCI)

Completed

Ziv-Aflibercept in Treating and Computed Tomography Perfusion Imaging in Predicting Response in Patients With Pancreatic Neuroendocrine Tumors That Are Metastatic or Cannot Be Removed by Surgery

Pancreatic Neuroendocrine Carcinoma | Multiple Endocrine Neoplasia Type 1

United States
Cairo University
Kasr El Aini Hospital; AL-Nour Eye Hospital

Completed

Avastin as an Adjunct to Diode Laser in the Treatment of Neovascular Glaucoma

Neovascular Glaucoma

Egypt
H. Lee Moffitt Cancer Center and Research Institute
Regeneron Pharmaceuticals; Genzyme, a Sanofi Company

Recruiting

Study of Cemiplimab Plus Ziv-Aflibercept for Subjects With Metastatic Uveal Melanoma

Metastatic Uveal Melanoma

United States
National Cancer Institute, Naples

Recruiting

Aflibercept or Bevacizumab as Second-line Treatment of RAS Mutated Metastatic Colorectal Cancer (ARBITRATION)

Metastatic Colorectal Cancer

Italy
EyePoint Pharmaceuticals, Inc.

Active, not recruiting

Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD) (DAVIO2)

Wet Age-related Macular Degeneration

United States
Imperial College London

Withdrawn

Combined Ranibizumab and Iluvien for Diabetic Macular Oedema (CASSIE)

Diabetes | Diabetic Macular Edema
Moorfields Eye Hospital NHS Foundation Trust
King's College London; University College, London

Recruiting

A Feasibility Randomised Controlled Trial of Early Vitrectomy for Post-operative Exogenous Endophthalmitis (EVIAN)

Endophthalmitis Postoperative Acute

United Kingdom
Regeneron Pharmaceuticals

Active, not recruiting

Study to Evaluate an 8 mg Aflibercept (EYLEA®) Prefilled Syringe (PFS)

Diabetic Macular Edema (DME) | Neovascular Age-Related Macular Degeneration (nAMD)

United States
Sindolor

Suspended

Safety and Efficacy of EZ-Ject Injector a Pain-Free Subcutaneous Automatic Injection in Healthy Volunteers

Healthy

Israel
Palmetto Retina Center, LLC

Completed

A Safety and Efficacy Trial of a Treat and Extend Protocol Using Ranibizumab With and Without Laser Photocoagulation for Diabetic Macular Edema (TREX-DME)

Diabetic Macular Edema

United States
EyePoint Pharmaceuticals, Inc.

Not yet recruiting

Study of EYP-1901 in Patients With Diabetic Macular Edema (DME) (VERONA)

Diabetic Macular Edema
AbbVie

Recruiting

Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD (ASCENT)

CNV | AMD | nAMD | Wet Age-related Macular Degeneration | wAMD | WetAMD

United States, Puerto Rico, Canada
Università degli Studi di Brescia

Completed

Treatment of CNV With Aflibercept Combined With Pranoprofen Eye Drops or Nutraceutical Support With Omega-3

Macular Edema
Hoffmann-La Roche

Completed

A Phase III Study to Evaluate the Port Delivery System With Ranibizumab Compared With Monthly Ranibizumab Injections in Participants With Wet Age-Related Macular Degeneration (Archway)

Neovascular Age-Related Macular Degeneration

United States
Bispebjerg Hospital

Active, not recruiting

Resistance Training and Injection Treatment for Achilles Enthesopathy

Achilles Entesopathy

Denmark
Regeneron Pharmaceuticals

Completed

Study to Assess the Efficacy, Safety, and Tolerability of Intravitreal Aflibercept Compared to Laser Photocoagulation in Patients With Retinopathy of Prematurity (BUTTERFLEYE)

Retinopathy of Prematurity

United States, Bulgaria, Hungary, Russian Federation, Thailand, Turkey, Colombia, Czechia, Korea, Republic of, Romania, Slovakia, Taiwan, Vietnam
Sanofi
Regeneron Pharmaceuticals

Terminated

Aflibercept Compared to Placebo in Term of Efficacy in Patients Treated With Gemcitabine for Metastatic Pancreatic Cancer (VANILLA)

Pancreatic Neoplasm

United States, France, Canada, Poland, Romania, Russian Federation, Germany, Italy, Spain, Switzerland, Bulgaria, India, Belgium, Czech Republic, Mexico, Argentina, Hungary, Colombia, Slovakia, Chile, Austria, Greece, Puerto Rico, Cyprus
Ciusss de L'Est de l'Île de Montréal

Recruiting

Thoracic Paravertebral Block Anesthesia for Breast Cancer Surgery (TPVB)

Breast Cancer | Breast Neoplasms | Breast Neoplasm Female | Cancer, Breast

Canada
Konya Meram State Hospital

Completed

Does Erector Spinal Block Improve Quality of Recovery After Laparoscopic Cholecystectomy

Postoperative Recovery

Turkey
University of Sao Paulo

Unknown

PASCAL Laser Versus ETDRS Laser Associated With Intravitreal Ranibizumab (IVR) Versus Only IVR for Proliferative Diabetic Retinopathy

Proliferative Diabetic Retinopathy

Brazil
Boehringer Ingelheim

Recruiting

A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy

Diabetic Retinopathy

United States
London North West Healthcare NHS Trust

Completed

Does Inspection of Colonic Mucosa During Insertion Improve Adenoma Detection? (INWARD)

Adenoma Colon | Serrated Adenoma

United Kingdom
Cellular Biomedicine Group Ltd.

Not yet recruiting

Allogenic Adipose-Derived Mesenchymal Progenitor Cells for the Treatment of Knee Osteoarthritis

Knee Osteoarthritis

China
National Taiwan University Hospital

Completed

Vitreous Levels of Cysteine-rich 61 in Patients With Proliferative Diabetic Retinopathy (VL)

Proliferative Diabetic Retinopathy

Taiwan
National Cancer Institute (NCI)

Terminated

Ganetespib and Ziv-Aflibercept in Refractory Gastrointestinal Carcinomas, Non-Squamous Non-Small Cell Lung Carcinomas, Urothelial Carcinomas, and Sarcomas

Neoplasms

United States
Assiut University

Active, not recruiting

Functional and Anatomical Outcomes of Dexamethasone Intra-vitreal Implant in Patients With Resistant Macular Edema Secondary to Retinal Vein Occlusion After Intravitreal Anti-VEGF Injection

Macular Edema | Retinal Vein Occlusion

Egypt
Prince of Songkla University

Completed

Intraocular Pressure Change Following Intravitreal Injection of Anti-vascular Endothelial Growth Factor Agent

Intraocular Pressure

Thailand
Inje University
Allergan

Unknown

Effect of Dexamethasone Implant in Hard Exudate Complicated With Diabetic Macular Edema

Diabetes Mellitus | Macular Edema | Retinal Exudates and Deposits

Korea, Republic of

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