Search clinical trials for: JAB-3068

Total 2374 results

Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A First-in-Human Study of JAB-3068 (SHP2 Inhibitor) in Adult Patients With Advanced Solid Tumors in China

Head and Neck Cancer | Esophageal Cancer | Non-small Cell Lung Cancer | Other Metastatic Solid Tumors

China
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A First in Human, Dose Escalation Study of JAB-3068 （SHP2 Inhibitor） in Adult Patients With Advanced Solid Tumors

Head and Neck Cancer | Esophageal Cancer | Non-small Cell Lung Cancer | Other Metastatic Solid Tumors

United States
Jacobio Pharmaceuticals Co., Ltd.
AbbVie

Recruiting

JAB-3068 Activity in Adult Patients With Advanced Solid Tumors

Non Small Cell Lung Cancer | Advanced Solid Tumor | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma

China
HK inno.N Corporation

Completed

Study to Evaluate the Pharmacokinetic Characteristics and Safety of IN-C004 in Healthy Volunteers

Healthy

Korea, Republic of
AbbVie

Completed

A Phase 2 Study of ABBV-3067 Alone and in Combination With ABBV-2222

Cystic Fibrosis

United States, Belgium, Canada, Czechia, France, Hungary, Netherlands, New Zealand, Poland, Slovakia, United Kingdom, Serbia
Genentech, Inc.

Completed

Ipatasertib (GDC-0068) Study to Evaluate Formulation Change and Food Effect on Bioavailability in Healthy Subjects

Cancer

United States
AlgoRx Pharmaceuticals

Completed

Efficacy and Safety of ALGRX 3268 in Management of Needlestick Pain in Children.

Procedural Pain

United States
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

Phase 1/2a Study of JAB-21822 Plus JAB-3312 in Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation

Colorectal Cancer | Non-small Cell Lung Cancer | Pancreatic Ductal Carcinoma | KRAS P.G12C

China
Genentech, Inc.

Completed

A Study Evaluating the Safety and Tolerability of GDC-0068 in Patients With Refractory Solid Tumors

Solid Cancers

Spain
AlgoRx Pharmaceuticals

Completed

Efficacy and Safety of ALGRX 3268 in Children Undergoing Minor Needle-Stick Procedures.

Pain

United States
AlgoRx Pharmaceuticals

Completed

Study of ALGRX 3268 for Needlestick Pain in Children

Pain

United States
University of Aarhus

Completed

Cerebral Responses During Bilateral/Unilateral Sacral Nerve Stimulation for Idiopathic Faecal Incontinence

Fecal Incontinence | Regional Cerebral Blood Flow

Denmark
Yale University

Terminated

FAAH Availability in Psychiatric Disorders: A PET Study

Post Traumatic Stress Disorder | Psychosis | Alcohol Use Disorder

United States
Genentech, Inc.

Completed

A Study of Ipatasertib in Participants With Mild, Moderate or Severe Hepatic Impairment Compared to Healthy Participants

Hepatic Insufficiency

United States
Hutchmed

Active, not recruiting

A Study of HMPL-306 in Advanced Solid Tumors With IDH Mutations

Isocitrate Dehydrogenase Gene Mutation

United States, Spain
Guy's and St Thomas' NHS Foundation Trust

Completed

Bond Failure of Two Types of Molar Buccal Tubes

Orthodontic Appliance Complication

United Kingdom
University of Michigan
National Institutes of Health (NIH)

Completed

Previously Implanted Pudendal Nerve Stimulation

Urinary Retention | Underactive Bladder

United States
University of Michigan
National Institutes of Health (NIH)

Completed

Pudendal Nerve Mapping Towards Improved Neuromodulation for Urinary Retention

Urinary Retention | Underactive Bladder

United States
Boehringer Ingelheim

Completed

Relative Bioavailability and Tolerability of Various Experimental Formulations of BIBV 308 SE in Healthy Subjects

Healthy
Jacobio Pharmaceuticals Co., Ltd.

Not yet recruiting

JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation

Solid Tumors
Jacobio Pharmaceuticals Co., Ltd.

Completed

A Food Effect Study of JAB-21822 in Healthy Subjects

Food Effect in Healthy Participants

China
Hutchmed

Recruiting

A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH

Isocitrate Dehydrogenase Gene Mutation

Spain, United States
Genentech, Inc.

Completed

A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0973 in Combination With GDC-0068 When Administered in Participants With Locally Advanced or Metastatic Solid Tumors

Neoplasms

United States, Spain
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A Study of JAB-21822 in Advanced or Metastatic NSCLC With KRAS p.G12C and STK11 Co-mutation and Wild-type KEAP1

Non-small Cell Lung Cancer

China
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

FIH Study of JAB-21822 in Adult Patients With Advanced Solid Tumors Harboring KRAS G12C Mutation in China

NSCLC | Solid Tumor | CRC

China
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Recruiting

Phase Ib/II Study of SHR-8068 Injection in the Treatment of Advanced Non-small Cell Lung Cancer

Advanced Non-small Cell Lung Cancer

China
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors

NSCLC | AML | SCLC | Ovarian Carcinoma | Malignant Tumor | ESCC | CRPC | MF

China
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A First-in-Human Study of JAB-8263 in Adult Patients With Advanced Solid Tumors

Solid Tumors, Adult

United States
Molecular NeuroImaging

Terminated

Evaluation of [123I] MNI-308 and SPECT as a Marker of Beta-amyloid Protein Deposition in AD Subjects Compared to HC

Alzheimer Disease

United States
Hutchison Medipharma Limited

Unknown

A Study of HMPL-306 in Patients With IDH1 and/or IDH2 Mutation of Relapsed/Refractory Myeloid Leukemia/Neoplasms

Acute Myeloid Leukemia

China
AbbVie

Completed

A Study to Assess How Food Affects the Safety and Pharmacokinetics of Galicaftor and Navocaftor (M23-492 FE)

Healthy Volunteers

United States
Eli Lilly and Company

Completed

A Study of the Effects of Multiple Doses of LY3372689 on the Brain in Healthy Participants

Healthy

United States
Eli Lilly and Company

Completed

A Study of the Effects of LY3372689 on the Brain in Healthy Participants

Healthy

United States
University of Aarhus
MEDTRONIC DANMARK A/S Arne Jacobsens Alle 17 DK-2300 København S Danmark

Terminated

Treatment of Faecal Incontinence With Sacral Nerve Stimulation - Improved Function With Stimulation Bilaterally? (SNS)

Fecal Incontinence

Denmark
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A Study of JAB-21822 in Patients With KRAS p.G12C Mutated Pancreatic Cancer

Pancreatic Cancer | KRAS P.G12C

China
Boehringer Ingelheim

Completed

Relative Bioavailability and Tolerability of Two New Different Extended Release Capsules of BIBV 308 SE, Versus a Solution of BIBV 308 SE in Healthy Subjects

Healthy
Jacobio Pharmaceuticals Co., Ltd.

Completed

Mass Balance Study of [14C]JAB-21822

Mass Balance Study in Healthy Subjects

China
Polichem S.A.

Completed

Clinical Trial on Onychomycosis With P-3058 Nail Solution in Pediatric Population

Onychomycosis

Belgium, Germany, Italy, Latvia, Spain
Air Force Military Medical University, China

Completed

Optimal Treatment Frequency of 308-Nm Excimer Laser for Vitiligo on the Face and Neck

Vitiligo

China
Tianjin Medical University Second Hospital

Not yet recruiting

Sintilimab After Stereotactic Ablation Brachytherapy for Refractory Oligometastatic Non-Small Cell Lung Cancer

Lung Neoplasms | Oligometastasis
University Hospital of North Norway

Completed

Treatment of Fecal Incontinence After Obstetric Anal Sphincter Injuries (KISS)

Fecal Incontinence

Norway
Dongkook Pharmaceutical Co., Ltd.

Recruiting

Efficacy and Safety of DKF-306 in Patients With Periodontal Diseases

Periodontal Diseases

Korea, Republic of
Celgene

Completed

Positron Emission Tomography (PET) Imaging Study to Evaluate Enzyme Availability in the Central Nervous System Before and After CC-97489 Administration in Healthy Participants

Healthy Volunteers

Belgium
AbbVie

Completed

A Study of the Safety, Tolerability and Pharmacokinetics of ABBV-368 as a Single Agent and Combination in Subjects With Locally Advanced or Metastatic Solid Tumors

Advanced Solid Tumors Cancer

United States, France, Japan, Puerto Rico, Spain, Taiwan
Chulalongkorn University
Ratchadapiseksompotch Fund

Unknown

Efficacy of 308-nm Excimer Laser for Primary Localized Cutaneous Amyloidosis Treatment in Asians

Lichen Amyloidosis

Thailand
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

JAB-2485 Activity in Adult Patients With Advanced Solid Tumors

Solid Tumors | ER+ Breast Cancer | ARID1A Gene Mutation | Triple Negative Breast Cancer, TNBC | Small Cell Lung Cancer, SCLC

United States, China
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A Study of JAB-3312 in Adult Patients With Advanced Solid Tumors in China

Breast Cancer | Colorectal Cancer | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Other Solid Tumors | Pancreatic Ductal Carcinoma

China
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

Safety and Efficacy of IBI389 Single Agent, and in Combination With Sintilimab, in Patients With Advanced Malignancies

Advanced Solid Tumors

China
AbbVie

Terminated

A Study to Assess the Effects of Multiple Study Drug Regimens in Subjects With Newly Diagnosed Locally Advanced Head and Neck Squamous Cell Carcinoma

Head and Neck Cancer

United States
The Catholic University of Korea

Unknown

Maintenance Therapy of 308-nm Excimer Laser Therapy in Patients With Vitiligo

Recurrence | Vitiligo | Maintenance Therapy | the 308-nm Excimer Laser

Korea, Republic of

Search clinical trials for: JAB-3068

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