Search clinical trials for: JAK Inhibitor

Total 65019 results

Takeda

Completed

A Study of Danavorexton (TAK-925) in Adults With Obstructive Sleep Apnea

Sleep Apnea

Australia
Millennium Pharmaceuticals, Inc.

Completed

Dose Escalation Study of MLN0128 in Participants With Advanced Malignancies

Advanced Solid Malignancies

United States, Spain
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability of TAK-788 Followed by Evaluation of the Effects of a Low-Fat Meal on TAK-788 PK and Evaluation of Relative Bioavailability of TAK-788 Capsules in Healthy Participants

Healthy Volunteers

United States
United States Naval Medical Center, San Diego

Completed

Jaw Elevation Device in Deep Sedation Study

Airway Obstruction

United States
Takeda

Terminated

Efficacy and Safety of Resatorvid in Patients With Sepsis-induced Cardiovascular and Respiratory Failure

Sepsis

Japan
Takeda

Completed

Efficacy of Ramelteon in Subjects With Chronic Insomnia

Sleep Initiation and Maintenance Disorders

United States
Akros Pharma Inc.

Completed

Safety, Tolerability and Pharmacokinetics Study Assessing Ascending Single Oral JTK-853 Doses in Healthy Subjects

Healthy

United States
Takeda

Completed

Safety and Efficacy of Dexlansoprazole Delayed-Release Capsules in Treating Symptomatic Non-Erosive Gastroesophageal Reflux Disease in Adolescents

Gastroesophageal Reflux Disease

United States, Poland, Belgium, Portugal, Italy, Hungary, Mexico, Brazil
Takeda

Completed

A Unblinded Study of TAK-438 (20 mg) for Prevention of Recurrence of Gastric or Duodenal Ulcer During Long-Term Low-Dose Aspirin Therapy

Gastric Ulcer | Duodenal Ulcer

Japan
Millennium Pharmaceuticals, Inc.

Completed

MLN0128 and MLN0128 + MLN1117 Compared With Everolimus in the Treatment of Adults With Advanced or Metastatic Clear-Cell Renal Cell Carcinoma

Clear-cell Metastatic Renal Cell Carcinoma

Spain, Czechia, United States, Canada, Italy, United Kingdom, France, Poland
University of Reading

Recruiting

Impact of Consumption of Cowpea Leaves on Blood Glucose

Blood Glucose

United Kingdom
Millennium Pharmaceuticals, Inc.
European Network of Translational Research in Ovarian Cancer - EUTROC; European...

Completed

A Study of Sapanisertib, Combination of Sapanisertib With MLN1117, Paclitaxel and Combination of Sapanisertib With Paclitaxel in Women With Endometrial Cancer

Endometrial Neoplasms

United States, Canada, Netherlands, Spain, Belgium, United Kingdom, Italy, Australia, Germany, Norway
Candan DOGAN
Ataturk University

Not yet recruiting

The Effect of Sujok Therapy on Symptom Burden and Comfort Level in Patients Undergoing Hemodialysis Treatment

Dialysis; Complications
Jacobio Pharmaceuticals Co., Ltd.

Recruiting

A Study of JAB-3312 in Adult Patients With Advanced Solid Tumors in China

Breast Cancer | Colorectal Cancer | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Other Solid Tumors | Pancreatic Ductal Carcinoma

China
Neurocrine Biosciences

Active, not recruiting

Study to Evaluate the Efficacy, Safety, and Tolerability of Luvadaxistat in Participants With Cognitive Impairment Associated With Schizophrenia (ERUDITE)

Schizophrenia

United States, Spain, Serbia, Czechia, Bulgaria, Mexico
Takeda

Available

Post-trial Access Program of Idursulfase-IT Along With Elaprase in Children With Hunter Syndrome

Hunter Syndrome

United States, Australia, Mexico, Spain, United Kingdom
Neurocrine Biosciences
Takeda

Completed

A Study to Evaluate 3 Dose Levels of Luvadaxistat of Adults With Negative Symptoms of Schizophrenia

Schizophrenia

Spain, United States, Bulgaria, Czechia, Germany, Italy, Poland, Ukraine
Takeda

Terminated

Fasiglifam 25 mg BID vs 50 mg QD

Type 2 Diabetes Mellitus

United States, Poland, Ukraine, Taiwan, Bulgaria, Romania, Slovakia
Takeda

Completed

Phase III Study of Intramuscular TAK-816 in Healthy Infants

Healthy Volunteers | Haemophilus Influenzae Type b, Prevention

Japan
Takeda

Completed

A Phase 1/2 Study of a Intramuscular Injection of TAK-850 in Healthy Adult Subjects

Influenza

Japan
Takeda

Completed

A Randomized, Double-Blind, Multicenter Study to Evaluate the Acid-inhibitory and Dose-response Efficacy of TAK-438 (20 mg, 40 mg) in Patients With Proton Pump Inhibitor (PPI) - Resistant Erosive Esophagitis

Erosive Esophagitis

Japan
Takeda

Completed

Ramelteon in Adults With Chronic Insomnia

Chronic Insomnia

United States
Takeda

Completed

Study of Efficacy of Ramelteon in Adults With Chronic Insomnia

Chronic Insomnia

United States
Takeda

Completed

Safety and Efficacy of Ramelteon in Healthy Subjects

Sleep Disorder

United States
Takeda

Completed

Efficacy of Ramelteon on Insomnia Symptoms Associated With Jet Lag in Healthy Adult Volunteers

Circadian Dysregulation

United States
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of TAK-906 in Adult Participants With Symptomatic Idiopathic or Diabetic Gastroparesis

Diabetic Gastroparesis | Idiopathic Gastroparesis

United States, Belgium, Japan, Poland
Ethicon Endo-Surgery

Completed

A Study of the ENSEAL® X1 Curved Jaw Tissue Sealer and Generator G11 in Thoracic, Urologic, and Ear, Nose, and Throat (ENT) Procedures

Thoracic Procedure | Urologic Procedure | Ear, Nose and Throat Procedure

United Kingdom, Japan, United States, Netherlands
Keimyung University Dongsan Medical Center

Completed

Two Handed Jaw-thrust on Postoperative Sore Throat After Double-lumen Endotracheal Tube Insertion

Lung Surgery

Korea, Republic of
Takeda

Withdrawn

A Phase 2 Study of a Subcutaneous Injection of TAK-850 in Healthy Adult Participants

Influenza Prevention

Japan
Takeda

Completed

Comparison of Vonoprazan to Esomeprazole in Participants With Symptomatic GERD Who Responded Partially to a High Dose of Proton Pump Inhibitor (PPI)

Gastroesophageal Reflux

Belgium, Bulgaria, Poland, Estonia, United Kingdom, Czechia
Takeda

Completed

Efficacy of TAK-438 Compared to AG-1749 (Lansoprazole) in the Maintenance Treatment of Healed Erosive Esophagitis

Erosive Esophagitis

Japan
Takeda

Completed

Study to Evaluate the Pharmacokinetics and Safety of Dexlansoprazole in Pediatric Subjects With Symptomatic Gastroesophageal Reflux Disease

Gastroesophageal Reflux

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of Ruxolitinib to the Usual Treatment (Tyrosine Kinase Inhibitors) for Chronic Myeloid Leukemia

Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive

United States
Clinica Universidad de Navarra, Universidad de...
Spanish National Health System

Unknown

Rituximab and Autologous Effector Lymphocytes in Non-Hodgkin Follicular Lymphoma in Response to First Line Chemotherapy

Follicular Lymphoma | Follicular Non-Hodgkin´s Lymphoma | Autologous Effector Lymphocytes

Spain
Millennium Pharmaceuticals, Inc.

Terminated

Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of Investigational Treatments in Combination With Standard of Care Immune Checkpoint Inhibitors in Participants With Advanced Melanoma

Melanoma

United States
Avera McKennan Hospital & University Health Center

Active, not recruiting

Evaluation of the Safety and Tolerability of TAK-228 With TAK-117 and Paclitaxel in Advanced Solid Tumors

Advanced Solid Tumor

United States
Takeda

Recruiting

An Absorption, Distribution, Metabolism, Excretion (ADME) Study of [14C]Subasumstat in Adults With Advanced or Metastatic Solid Tumors

Solid Tumors

Hungary
Takeda
Nimbus Lakshmi, Inc.

Completed

A Study to Evaluate the Efficacy, Safety, and Tolerability of NDI-034858 in Participants With Active Psoriatic Arthritis

Psoriatic Arthritis

United States, Czechia, Germany, Poland
Takeda

Completed

A Study of REPLAGAL® in Treatment-naive Chinese Participants With Fabry Disease

Fabry Disease

China
Takeda

Completed

Expanded Access Program With Lanadelumab for Japanese People With Hereditary Angioedema

Hereditary Angioedema

Japan
Takeda

Completed

Special Drug Use Surveillance of Vonoprazan for "Maintenance Therapy of Reflux Esophagitis: Long-term Use"

Reflux Esophagitis

Japan
Takeda

Completed

A Phase 2 Efficacy and Safety Study of TAK-063 in Participants With an Acute Exacerbation of Schizophrenia

Schizophrenia

United States
Takeda

Terminated

Efficacy and Safety of Ramelteon Sublingual as Adjunctive Therapy for Maintenance Treatment of Bipolar I Disorder

Bipolar Disorder

United States, Argentina, Chile, Colombia, Mexico
Takeda

Terminated

Safety and Efficacy Study of Ramelteon (TAK-375) Tablets for Sublingual Administration (SL) in Adults With Bipolar 1 Disorder

Bipolar Disorder

United States, Ukraine, United Kingdom, Germany, Bulgaria, Romania, Serbia, Russian Federation, Czech Republic, Poland
Takeda

Terminated

Efficacy of Lapaquistat Acetate in Subjects With Hypercholesterolemia

Hypercholesterolemia

United States
Hama University

Completed

The Efficacy of Tow Mechanics for Total-maxillary-arch-distalization

Malocclusion | Class II Division 1 Malocclusion

Syrian Arab Republic
Takeda

Completed

A Study to Evaluate the Bioequivalence (BE) and the Food Effect of TAK-438ASA Tablet

Healthy Volunteers

Japan
Takeda

Completed

TAK-438_110 Drug Interaction With Cytochrome P450 3A4 (CYP3A4) Inhibitor Clarithromycin

Healthy Volunteers
Takeda

Active, not recruiting

A Study of TAK-062 in Treatment of Active Celiac Disease in Participants Attempting a Gluten-Free Diet

Celiac Disease

United States, Belgium, Poland, Italy, Canada, United Kingdom, France, Spain
Takeda

Completed

Efficacy of TAK-438 Compared to AG-1749 (Lansoprazole) in the Treatment of Erosive Esophagitis

Erosive Esophagitis

Japan

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