Search clinical trials for: JP-1366 placebo

Total 53666 results

Glycemic Index Laboratories, Inc
DSM Nutritional Products, Inc.

Completed

Effect of Consuming Oat Bran Mixed in Water Before a Meal on Glycemic Responses in Healthy Humans - a Pilot Study

Glucose Intolerance
Terumo Europe N.V.

Completed

Holmium-166 Retrospective Collection of Real-World Data (RECORD)

Hepatocellular Carcinoma | Metastatic Cancer

Netherlands, Germany, Switzerland, Belgium, Spain, Portugal, Italy
MediciNova
Wake Forest University Health Sciences

Completed

Ibudilast (MN-166) in Subjects With Amyotrophic Lateral Sclerosis (ALS) (IBU-ALS-1201)

Amyotrophic Lateral Sclerosis

United States
Beijing Chest Hospital
Shandong Chest Hospital; Zhengzhou Sixth People's Hospital

Active, not recruiting

Early Bactericidal Activity Safety Pulmonary Tuberculosis Pyrifazimine (TBI-166)

Sensitive Pulmonary Tuberculosis

China
UMC Utrecht

Unknown

Surefire Infusion System vs. Standard Microcatheter Use During Holmium-166 Radioembolization (SIM)

Liver Diseases | Digestive System Neoplasms | Neoplasm Metastasis | Colorectal Neoplasms

Netherlands
Boehringer Ingelheim

Completed

Pharmacokinetics and Pharmacodynamics of Multiple 5 mg Doses of BI 1356 p.o. Given Once Daily Compared to Multiple 2.5 mg Doses Given Twice Daily in Healthy Male and Female Volunteers

Healthy
Wyeth is now a wholly owned subsidiary of Pfizer

Withdrawn

Study Evaluating Safety and Tolerability of Vabicaserin in Patients With Sudden Worsening of Schizophrenia

Schizophrenia
Boehringer Ingelheim

Completed

Bioavailability of Combination Tablet BI 1356/Metformin Compared With Single BI 1356 and Metformin Administered Together to Healthy Male and Female Subjects

Healthy
Shanghai Shengdi Pharmaceutical Co., Ltd

Recruiting

A Study of Chemoradiotherapy With SHR-1316 For Treatment of Locally Advanced Cervical Cancer

Locally Advanced Cervical Cancer

China
Kawin Technology Share-holding Co., Ltd.
KawinGreen Biotech Co., Ltd.

Completed

Safety and Efficacy of KW-136 and Sofosbuvir for Treatment of Chronic Hepatitis C (KW-136_II)

Hepatitis C, Chronic

China
Poniard Pharmaceuticals

Terminated

Study Comparing STR (Skeletal Targeted Radiotherapy) Plus Melphalan to Melphalan Alone, With Stem Cell Transplant in Multiple Myeloma

Multiple Myeloma

United States, Canada
Boehringer Ingelheim

Completed

Bioavailability of BI 1356 and Glyburide in Healthy Male and Female Volunteers

Healthy
Boehringer Ingelheim

Completed

Bioavailability of BI 1356 With and Without Co-administration of Pioglitazone and the Bioavailability of Pioglitazone With and Without Coadministration of BI 1356 in Healthy Male and Female Volunteers

Healthy
Shanghai Zhongshan Hospital

Recruiting

NeoAdjuvant Therapy With Immunoreagent (SHR-1316) for Resectable Oesophageal Squamous Cell carciNoma (NATION1907II)

Oesophageal Squamous Cell Carcinoma

China
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating SCA-136 in Subjects With Acute Exacerbations of Schizophrenia

Schizophrenia

United States
Kawin Technology Share-holding Co., Ltd.
KawinGreen Biotech Co., Ltd.

Completed

KW-136 With Sofosbuvir for Chinese Adults With Chronic Hepatitis C (KW-136_III)

Hepatitis C, Chronic

China
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

A Study of Fluzoparib (SHR-3162) and Temozolomide With or Without SHR-1316 in Treating Patients With Replapsed Small Cell Lung Cancer

Small Cell Lung Cancer

China
LG Life Sciences

Completed

Study of LC23-1306 in Healthy Male Subjects

Acute Coronary Syndrome

Korea, Republic of
Boehringer Ingelheim

Completed

Effect of BI 1356 as Single Dose on the QT Interval in Healthy Female and Male Subjects

Healthy
Shengjing Hospital
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

Breast Cancer Study of Stereotactic Body Radiation Therapy (SBRT) Combined Neoadjuvant Treatment

Breast Cancer

China
Haukeland University Hospital

Completed

Hypertonic Saline-hetastarch in Cardiac Surgery (HH)

Postoperative Cardiorespiratory Failure

Norway
Mati Therapeutics Inc.

Completed

Safety and Intraocular Lowering Effect of Delivery of Travoprost Evolute® in Subjects With Elevated Intraocular Pressure

Elevated Intraocular Pressure (IOP)

United States
Boehringer Ingelheim

Completed

Investigation of the Metabolism and Pharmacokinetics of 10 mg [14C] BI 1356 Administered Orally Compared to 5 mg [14C] BI 1356 Administered Intravenously in Healthy Male Volunteers

Healthy
Boehringer Ingelheim

Completed

Randomized, Double-blind (db), Placebo-controlled 18 Week Study of Linagliptin (BI 1356) in Type 2 Diabetic Patients With Insufficient Glycaemic Control on a Sulfonylurea Drug

Diabetes Mellitus, Type 2

United States, Argentina, Hungary, India, Japan, Poland, Russian Federation
Boehringer Ingelheim

Completed

Safety and Efficacy in Type 2 Diabetic Patients With Severe Chronic Renal Impairment, 5 mg BI 1356 (Linagliptin) vs. Placebo, Insulin Background Inclusive

Diabetes Mellitus, Type 2

United States, Australia, Hong Kong, Israel, New Zealand, Ukraine
Jiangsu HengRui Medicine Co., Ltd.

Enrolling by invitation

The Study is Being Conducted to Evaluate the Efficacy and Safety of SHR-1316 in Combination With Chemo-radiotherapy in Patients With LS-SCLC.

Small-cell Lung Cancer

China
Janssen Research & Development, LLC
Pharmacyclics LLC.

Completed

A Study to Assess the Absolute Bioavailability of Oral PCI-32765 and the Effect of Grapefruit Juice on the Bioavailability of PCI-32765 in Healthy Participants

Healthy Volunteer

Belgium
National Institute of Neurological Disorders and...

Completed

JP-1730 to Treat Parkinson's Disease

Parkinson Disease

United States
UCB Pharma SA

Completed

Long Term Follow up Treatment With Levetiracetam in Subjects of 4 Years and Older With Generalized Epilepsy

Generalized Epilepsy
Janssen Research & Development, LLC
GlaxoSmithKline

Completed

A Study Comparing Sirukumab (CNTO 136) Monotherapy With Adalimumab (HUMIRA®) Monotherapy in the Treatment of Active Rheumatoid Arthritis (SIRROUND-H)

Arthritis, Rheumatoid

United States, Poland, Ukraine, Germany, Spain, Colombia, Mexico, Bulgaria, Romania, Serbia, South Africa, Chile, Russian Federation, Hungary, Lithuania, Moldova, Republic of
Sir Run Run Shaw Hospital

Recruiting

The Efficacy and Safety of Short-course Radiation Combined With Adebrelimab and CAPEOX Neo-adjuvant Therapy for Organ-retention in Patients With MSS/pMMR Ultra Low Rectal Adenocarcinoma

Rectal Adenocarcinoma

China
Boehringer Ingelheim

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BI 1356 BS in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2
Dr. Yoram Shir
McGill University; Louise & Alan Edwards Foundation

Terminated

The Effect of Soy Protein on Neuropathic Pain

Neuralgia

Canada
Ege University

Completed

Care to Caregiver: The Effect of Reflexology on Sleep and Anxiety of Cancer Caregiver

Sleep | Anxiety

Turkey
The First Affiliated Hospital of Zhengzhou University

Recruiting

Study of Anti-PD-1/PD-L1 Antibody Plus Apatinib as Second-Line Treatment of Advanced Esophageal Squamous Cell

Esophageal Cancer

China
Mian XI

Recruiting

Combination of SBRT, PD-L1 Inhibitor, and Lenvatinib in Hepatocellular Carcinoma (HSBRT2401) (HSBRT2401)

Hepatocellular Carcinoma

China
Capital Medical University

Completed

The Effects of Lowering Dialysate Sodium in Hypertensive Hemodialysis Patients

Arteriosclerosis | Hypertension | Left Ventricular Hypertrophy

China
Assistance Publique - Hôpitaux de Paris
Iltoo Pharma

Completed

Low Dose IL-2 Therapy in Patients With a Depressive Episode in the Course of a Bipolar Disorder (DEPIL-2)

Bipolar Depression

France
Washington University School of Medicine

Completed

Alirocumab and Reverse Cholesterol Transport

Atherosclerosis | Coronary Heart Disease

United States
Orphan Australia

Completed

VSL#3 Versus Placebo in Maintenance of Remission in Crohn's Disease

Crohn's Disease

Australia
First Affiliated Hospital of Fujian Medical University

Recruiting

A Study of Adebrelimab in Combination With Apatinib Gemcitabine and Cisplatin in Biliary Tract Malignancies

Biliary Tract Malignancies

China
Nowarta Biopharma Inc

Completed

A Phase I/II Double-blind Safety and Efficacy Evaluation of Nowarta110 in Patients With Plantar Warts

Plantar Warts

United States
MediciNova

Active, not recruiting

Efficacy, Safety, Tolerability, and Biomarkers of MN-166 (Ibudilast) in Patients Hospitalized With COVID-19 and at Risk for ARDS

Pneumonia, Viral

United States
Chinese University of Hong Kong

Recruiting

RCT for Yinqiaosan-Maxingganshitang in the Treatment of COVID-19

COVID-19

Hong Kong
National University of Malaysia
Malaysia Palm Oil Board

Unknown

Supplementation of Oil Palm Phenolics to Healthy Participants (SPIRAL)

Cardiovascular Diseases | Hypercholesterolemia | Hyperlipidemias

Malaysia
Harbin Medical University

Not yet recruiting

HAIC+Adebrelimab+Lenvatinib for Conversion Treatment of Potentially Resectable, Locally Advanced Biliary Tract Cancer

Biliary Tract Cancer
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

A Phase I Study of HRS2300 or Combined With SHR-1316 or SHR-1701 or Trametinib or Almonertinib in Patients With Advanced Malignancies

Advanced Malignancies

China
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA); MediciNova

Completed

Effects of Ibudilast on Oxycodone Self-administration in Opioid Abusers

Opioid Dependence | Opioid Abuse

United States
MediciNova

Recruiting

Evaluation of MN-166 (Ibudilast) for 12 Months Followed by an Open-label Extension for 6 Months in Patients With ALS (COMBAT-ALS)

Amyotrophic Lateral Sclerosis

United States, Canada
Fudan University
Chongqing University Cancer Hospital; Sun Yat-sen University; Peking University... and other collaborators

Recruiting

Immune Therapy in HR-positive/HER2-negative Metastatic Breast Cancer(ENIGMA)-BCTOP-L-M02

Breast Cancer | Metastatic Cancer

China

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