Search clinical trials for: KYN-5356

Total 255 results

Bristol-Myers Squibb

Recruiting

ELEMENT-MDS: A Study to Compare the Efficacy and Safety of Luspatercept in Participants With Myelodysplastic Syndrome (MDS) and Anemia Not Receiving Blood Transfusions (ELEMENT-MDS)

Myelodysplastic Syndromes

Canada, United States, China, Australia, France, Greece, Hungary, Germany, Italy, Czechia, Poland, Spain, Brazil, Colombia, India, Mexico, Argentina, Puerto Rico
Boehringer Ingelheim

Completed

Efficacy and Safety of BI 1356 in Combination With Metformin in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Bulgaria, Denmark, France, Germany, Hong Kong, Hungary, India, Ireland, Italy, Netherlands, Norway, Poland, South Africa, Sweden, United Kingdom
Boehringer Ingelheim

Completed

Japanese P III vs Voglibose and Placebo

Diabetes Mellitus, Type 2

Japan
Julie Dawson

Completed

The Use of Topical Anaesthetic in the Banding of Internal Haemorrhoids (TAB)

Hemorrhoids

United Kingdom
Boehringer Ingelheim

Completed

Effect of BI 1356 as Single Dose on the QT Interval in Healthy Female and Male Subjects

Healthy
Generex Biotechnology Corp.
Hoffmann-La Roche; Nextrials, Inc.; eResearch Technology, Inc.; OSMOS Clinical... and other collaborators

Unknown

Active Comparator Study of Generex Oral-lyn™ Spray and Injected Human Insulin

Diabetes Mellitus

United States, Bulgaria, Canada, Ecuador, Poland, Puerto Rico, Romania, Russian Federation, Ukraine
Takeda

Completed

A Study of TAK-536 in Children From 2 to Less Than 6 Years Old With High Blood Pressure

Hypertension

Japan
University of Florida
Wakunaga Pharmaceutical Co., Ltd.

Completed

Probiotics and Health-related Quality of Life in Individuals With Seasonal Allergies (JEN)

Healthy

United States
Kyowa Kirin Co., Ltd.

Completed

A Through QT/QTc Study of KW-6356

Parkinson's Disease

Japan
Takeda

Completed

A Phase 1 Food Effect Study of Azilsartan (TAK-536) Pediatric Formulation

Healthy Volunteers

Japan
Takeda

Completed

A Phase 1, Bio-equivalence Study of TAK-536 Pediatric Formulation

Japanese Healthy Adult Male Participants

Japan
Takeda

Completed

A Phase 3 Pharmacokinetic Study of TAK-536 (Azilsartan) in Pediatric Patients 6 to Less Than 16 Years With Hypertension

Pediatric Hypertension

Japan
Florida State University

Completed

MI-CBT Adherence Program for Lifestyle Interventions in Older Adults (MI-CBT KNAP)

Mild Cognitive Impairment | Ketosis | Adherence, Patient

United States
Church & Dwight Company, Inc.

Completed

Repeated Insult Patch Test of Personal Lubricants

Edema | Erythema
Al-Iraqia University

Completed

Miswak Efficacy Compared With Chlorhexidine (MiswakChlorx)

Gingivitis

Iraq
Boehringer Ingelheim

Completed

Randomized, Double-blind (db), Placebo-controlled 18 Week Study of Linagliptin (BI 1356) in Type 2 Diabetic Patients With Insufficient Glycaemic Control on a Sulfonylurea Drug

Diabetes Mellitus, Type 2

United States, Argentina, Hungary, India, Japan, Poland, Russian Federation
Boehringer Ingelheim

Completed

Safety and Efficacy in Type 2 Diabetic Patients With Severe Chronic Renal Impairment, 5 mg BI 1356 (Linagliptin) vs. Placebo, Insulin Background Inclusive

Diabetes Mellitus, Type 2

United States, Australia, Hong Kong, Israel, New Zealand, Ukraine
Johnson & Johnson Healthcare Products Division...

Completed

Safety Study of a Sensitive Sensual Touch and Personal Lubricant

Inadequate Lubrication

United States
Takeda

Completed

A Phase 3 Long-term Study of TAK-536 in Pediatric Patients 6 to Less Than 16 Years With Hypertension

Pediatric Hypertension

Japan
Stanford University
Kyverna Therapeutics

Recruiting

A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell ( CAR-T) Therapy in Subjects With Non-relapsing and Progressive Forms of Multiple Sclerosis

Multiple Sclerosis | Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive

United States
Duke University
Foundation Fighting Blindness

Withdrawn

The Dark-Adapted Retinal Function Response in Choroideremia (DARC) Study (DARC)

Choroideremia

United States
Synthetic Biologics Inc.

Completed

A Study Evaluating the Effect of Esomeprazole on SYN-004 Degradation of Ceftriaxone In Adults With an Ileostomy

Healthy Volunteers With Ileostomy

Canada
Boehringer Ingelheim

Completed

Pharmacokinetics and Pharmacodynamics of BI 1356 in Subjects With Different Degrees of Liver Impairment as Compared to Healthy Subjects

Hepatic Insufficiency
Church & Dwight Company, Inc.

Completed

14-Day Cumulative Irritation Patch Test in Subjects With Normal Skin

Cumulative Irritation

United States
David Porter
Kyverna Therapeutics

Not yet recruiting

CARTIMMUNE: Study of Patients With Autoimmune Diseases Receiving KYV-101 (CARTIMMUNE)

Diffuse Cutaneous Systemic Sclerosis | ANCA Associated Vasculitis | Idiopathic Inflammatory Myopathies | SLE Nephritis
Boehringer Ingelheim

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BI 1356 BS in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2
Teva takeda

Active, not recruiting

A Study of Azilsartan in Children From 6 to Less Than 16 Years Old With High Blood Pressure

Hypertension

Japan
Boehringer Ingelheim

Completed

Pharmacokinetics of Single and Multiple Oral Doses of BI 1356 in Healthy Chinese Volunteers

Healthy
Boehringer Ingelheim

Completed

Bioavailability of BI 1356 Administered With and Without Food to Healthy Male and Female Subjects

Healthy
Boehringer Ingelheim

Completed

Bioavailability of BI 1356 BS and Metformin After Co-administration Compared to the Bioavailability of BI 1356 BS Alone and Metformin Alone in Healthy Male Volunteers

Healthy
Boehringer Ingelheim

Completed

Bioavailability of Warfarin After Coadministration With Multiple Doses of BI 1356 Compared to the Bioavailability of Warfarin Alone in Healthy Male Volunteers

Healthy
Sangart

Completed

Phase III Study of Hemospan® to Prevent Hypotension in Hip Arthroplasty

Ischemia | Hypotension

Netherlands, Belgium, Czech Republic, Sweden, Poland, United Kingdom
Boehringer Ingelheim

Completed

Pharmacokinetics, Safety and Tolerability of Digoxin With or Without Co-administration of BI 1356 in Healthy Volunteers

Healthy
Lyndra Inc.

Completed

Study to Evaluate the Pharmacokinetics (PK) and Safety/Tolerability of Long-Acting Oral LYN-005

Schizophrenia | Schizoaffective Disorder

United States
Mikkael Sekeres, MD
Bristol-Myers Squibb; Celgene

Recruiting

Luspatercept and Lenalidomide (L2) in Lower-risk, Non-del(5q) MDS Patients

Myelodysplastic Syndromes

United States
Kyverna Therapeutics

Not yet recruiting

A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Systemic Sclerosis

Systemic Sclerosis | Systemic Sclerosis - Diffuse Cutaneous | Systemic Sclerosis - 2013 ACR/EULAR Classification Criteria
Takeda

Completed

Efficacy and Safety of Azilsartan in Participants With Mild to Moderate Uncomplicated Essential Hypertension

Essential Hypertension
Assistance Publique - Hôpitaux de Paris
GIS EPI-PHARE

Unknown

Long-term Use of Drugs That Could Prevent the Risk of Serious COVID-19 Infections or Make it Worse (TRAPSAH)

AMD, ACEi's/ARB Prevent/Worsen Risk of COVID-19 Infection

France
Chong Kun Dang Pharmaceutical

Completed

Study to Evaluate the Bioequivalence of Astellas Phama Korea Inc. "Harnal-D" in Healthy Volunteers

Benign Prostatic Hyperplasia

Korea, Republic of
Chong Kun Dang Pharmaceutical

Completed

Study to Evaluate the Bioequivalence of Astellas Phama Korea Inc. "Harnal-D" in Healthy Volunteers After Meal

Benign Prostatic Hyperplasia

Korea, Republic of
Kyverna Therapeutics

Not yet recruiting

A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, in Subjects With Refractory Generalized Myasthenia Gravis

Generalized Myasthenia Gravis | Myasthenia Gravis
Takeda

Completed

Efficacy and Safety of Azilsartan in Subjects With Essential Hypertension

Hypertension
Lyndra Inc.
Worldwide Clinical Trials

Completed

A Multiple Dose Study to Assess the Safety, Tolerability and PK of Risperidone Extended Release Capsules

Schizophrenia Schizoaffective

United States
Yale University
Celgene; Kyowa Kirin Co., Ltd.

Completed

Combination of Lenalidomide and Autologous Mature Dendritic Cells Pulsed With KRN7000 in Myeloma

Myeloma

United States
Islamic Azad University, Tehran

Completed

A Comparison of Mouth Rinse Containing Alcohol-free Chlorhexidine With a Cetylpyridinium Chloride in Periodontal Diseases

Periodontal Diseases
Takeda

Terminated

Efficacy, Safety and Tolerability of Pioglitazone-Azilsartan in Subjects With Type 2 Diabetes Mellitus

Type 2 Diabetes

United States, Argentina, Mexico, Chile, Peru
Kyverna Therapeutics

Recruiting

A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis (KYSA-3)

Lupus Nephritis | Lupus Nephritis - WHO Class IV | Lupus Nephritis - WHO Class III

Germany
Kyverna Therapeutics

Recruiting

A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis

Lupus Nephritis | Lupus Nephritis - World Health Organization (WHO) Class III | Lupus Nephritis - WHO Class IV

United States
Roswell Park Cancer Institute

Completed

Comparing Nicotine Delivery, Subjective Effects, and Sensory Experiences of Tobacco Users Using Oral Nicotine Products and Electronic Cigarettes [ZYN Study]

Tobacco Use | Tobacco Smoking | Cigarette Smoking | Smokeless Tobacco Cessation

United States
Takeda

Completed

Efficacy and Safety of Pioglitazone and Azilsartan in Treating Subjects With Type 2 Diabetes Mellitus

Diabetes Mellitus

United States, Argentina, Mexico, Peru, Chile

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