Search clinical trials for: LCZ696 matching placebo

Total 54349 results

Syneos Health
Otsuka Pharmaceutical Development & Commercialization, Inc.

Terminated

To Assess the Safety, Tolerability and Pharmacokinetics of ACH-000029 in Healthy Subjects

Healthy Volunteers

Australia
University of Chicago

Active, not recruiting

Effects of Flibanserin on the Pre- and Post-menopausal Female Brain

Hypoactive Sexual Desire Disorder

United States
CuraSen Therapeutics, Inc.

Completed

A Study of CST-2032 and CST-107 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Parkinson's or Alzheimer's Disease

Dementia | Mild Cognitive Impairment

United States, New Zealand
Regeneron Pharmaceuticals

Completed

Safety and Tolerability of Regeneron Anti-SARS-CoV-2 Monoclonal Antibody/Ies in Adult Healthy Volunteers as Related to COVID-19

Healthy

Belgium
Kallyope Inc.

Completed

A Study to Evaluate the Safety, Tolerability, and Weight Loss Efficacy of K-757 Alone and in Combination With K-833

Obesity

United States
Novartis Pharmaceuticals

Completed

randOmized stUdy Using acceleromeTry to Compare Sacubitril/valsarTan and Enalapril in Patients With Heart Failure (OUTSTEP-HF)

Chronic Heart Failure With Reduced Ejection Fraction

Belgium, Estonia, Denmark, Greece, United Kingdom, Germany, Latvia, Lithuania, Spain, Netherlands, Bulgaria, Finland, Poland, Czechia, Iceland, Sweden, France, Ireland, Norway
Regeneron Pharmaceuticals

Recruiting

A Trial to Learn if Single Ascending Intravenous (IV) Doses of REGN7508 Are Safe and Well Tolerated, and How it Works in the Body of Healthy Adult Participants

Healthy Volunteer

United Kingdom
Biogen

Recruiting

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of BIIB115

Healthy Volunteer | Muscular Atrophy, Spinal

Germany, Belgium, Italy, Poland, Netherlands, Canada, France, United Kingdom
Sun Pharma Advanced Research Company Limited

Completed

Study to Determine Safety, Tolerability and Pharmacokinetics, of SCO-120 in Healthy Male and Post-menopausal Female Subjects

Healthy Volunteer Study

United States, Canada
Jiangsu HengRui Medicine Co., Ltd.

Completed

Multicentre, Randomised Phase III Study of the Efficacy and Safety of Hetrombopag Olamine in Idiopathic Thrombocytopenic Purpura (ITP) Patient

Idiopathic Thrombocytopenic Purpura

China
Regeneron Pharmaceuticals
Sanofi

Terminated

Efficacy, Safety, and Pharmacokinetic Profiles of REGN3500 Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis

Atopic Dermatitis

United States, Hungary, Korea, Republic of, Germany, Japan, Poland, Australia, Canada, Czechia, Spain, United Kingdom
Bayer

Terminated

Assess Safety and Efficacy of Vilaprisan in Subjects With Endometriosis (VILLENDO)

Endometriosis

United States, Austria, Japan, Poland, Finland, Canada, Italy, Czechia
Cerevel Therapeutics, LLC

Completed

A Multiple Ascending Dose Trial of CVL-231 in Subjects With Schizophrenia

Schizophrenia

United States
Naurex, Inc, an affiliate of Allergan plc

Completed

A Study of Rapastinel as Adjunctive Therapy in the Prevention of Relapse in Patients With Major Depressive Disorder

Depressive Disorder, Major

United States
Regeneron Pharmaceuticals

Withdrawn

Safety and Efficacy of REGN2477+REGN1033 in Patients With Sporadic Inclusion Body Myositis

Sporadic Inclusion Body Myositis
Cyclerion Therapeutics

Completed

Trial of IW-1701 (A Stimulator of Soluble Guanylate Cyclase (sGC)) in Healthy Volunteers

Healthy

United States
Allergan

Completed

Efficacy, Safety, and Tolerability Study of Oral Ubrogepant in the Acute Treatment of Migraine (ACHIEVE I)

Migraine, With or Without Aura

United States
AbbVie

Completed

Safety and Pharmacodynamic Study of ABT-436 in Major Depressive Disorder

Major Depressive Disorder
Amgen

Completed

Safety Study of AMG 557 in Subjects With Lupus Arthritis

Lupus Arthritis, Systemic Lupus Erythematosus

United States, Taiwan, Germany, Denmark, Australia, United Kingdom, Malaysia, France
Ironwood Pharmaceuticals, Inc.

Completed

Trial of IW-9179 in Patients With Diabetic Gastroparesis (DGP)

Diabetic Gastroparesis

United States
Eisai Co., Ltd.

Completed

Single/ Multiple-Dose Study of E6007 in Healthy Japanese Male Subjects

Healthy Volunteers

Japan
Eisai Co., Ltd.

Completed

A Study to Assess Safety, Tolerability, and Pharmacokinetics of E2307 in Healthy Young and Elderly Japanese Subjects

Healthy Subjects

Japan
Idorsia Pharmaceuticals Ltd.

Completed

Clinical Study to Investigate the Biological Activity, Safety, Tolerability, and Pharmacokinetics of ACT-334441 in Subjects With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States, Belarus, Bulgaria, Georgia, Russian Federation, Ukraine
Sucampo Pharma Americas, LLC
Sucampo Pharmaceuticals, Inc.

Terminated

Efficacy and Safety of Cobiprostone in Patients With Portal Hypertension

Portal Hypertension

United States
Idorsia Pharmaceuticals Ltd.

Completed

Clinical Study to Explore the Efficacy of ACT-129968 in Patients With Partly Controlled Asthma (CONTROL)

Asthma

United States, Australia, Bulgaria, Germany, Hungary, Israel, Poland, Russian Federation, Serbia, Singapore, South Africa, Sweden, Ukraine
Tsumura USA
Syneos Health

Terminated

A Safety and Efficacy Study of Daikenchuto (TU-100) to Treat Crohn's Disease

Crohn's Disease

United States
Novartis Pharmaceuticals

Completed

Efficacy and Safety of LCZ696 Compared to Olmesartan in Essential Hypertensive Patients Not Responsive to Olmesartan

Hypertension

United States, Spain, Philippines, Guatemala, Russian Federation, Argentina, Puerto Rico
Novartis Pharmaceuticals

Completed

Study of Effects of Sacubitril/Valsartan vs. Enalapril on Aortic Stiffness in Patients With Mild to Moderate HF With Reduced Ejection Fraction (EVALUATE-HF)

Heart Failure and Reduced Ejection Fraction

United States
ViiV Healthcare

Recruiting

Proof of Concept Treatment Study of Orally Administered VH4004280 or VH4011499 in HIV-1 Infected Adults (CINNAMON)

HIV Infections

United States, France, Italy, Spain, Germany, Canada, Mexico, Argentina, United Kingdom
Nathura S.p.A
Evidilya S.r.l.

Recruiting

Performance and Safety of Class IIb MD Celegyn® in VVA

Vulvovaginal Atrophy

Italy
Sun Pharmaceutical Industries Limited

Active, not recruiting

Efficacy and Safety of Tildrakizumab Compared to Placebo in Anti-TNF naïve Subjects With Active Psoriatic Arthritis II (INSPIRE 2)

Active Psoriatic Arthritis

United States, Australia, Czechia, Germany, India, Japan, Korea, Republic of, Poland, Spain
Equilibre Biopharmaceuticals B.V.

Terminated

Study of EQU-001 for Uncontrolled Focal Onset Seizures

Focal Onset Seizures

United States, Israel
Merit E. Cudkowicz, MD
Clene Nanomedicine

Completed

HEALEY ALS Platform Trial - Regimen C CNM-Au8

Amyotrophic Lateral Sclerosis

United States
Bayer

Completed

Study to Gather Information About the Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following an Acute Heart Attack (PACIFIC-AMI)

Acute Myocardial Infarction

Spain, Japan, Belgium, United States, Czechia, Hungary, Switzerland, Netherlands, Germany, Austria, Poland, Italy, Sweden, United Kingdom
Astellas Pharma Global Development, Inc.

Terminated

A Study to Find a Suitable Dose of ASP8731 and Check for Medical Problems at Each Dose in Healthy Adults

Healthy Participants

United States
Janssen Pharmaceutical K.K.

Completed

A Study of JNJ-40411813 in Healthy Japanese Male Participants

Healthy

Japan
Kangpu Biopharmaceuticals, Ltd.

Completed

Safety, Tolerability and Pharmacokinetics of KPG-818 in Healthy Subjects

Systemic Lupus Erythematosus

United States
Merck Sharp & Dohme LLC

Completed

Single Rising Dose Study of MK-8723 in Healthy Participants and Participants With Immune Thrombocytopenia Purpura (MK-8723-001)

Immune Thrombocytopenia Purpura
Axikin Pharmaceuticals, Inc.

Completed

A Phase IIa Repeat Dose AXP1275 vs Placebo Cross-over Trial With Pulmonary Allergen Challenge in Adults With Asthma

Atopic Asthma

Canada
Topokine Therapeutics, Inc.

Unknown

Phase 2 Study of TAT4 Gel for Reduction of Nasolabial Folds

Nasolabial Folds

United States
Glenmark Pharmaceuticals Ltd. India
Glenmark Pharmaceuticals S.A.

Completed

A Clinical Trial to Study the Effects GRC 17536 in Patients With Painful Diabetic Peripheral Neuropathy (Painful Extremities Due to Peripheral Nerve Damage in Diabetic Patients).

Painful Diabetic Peripheral Neuropathy

India, Czech Republic, Germany, United Kingdom
Boehringer Ingelheim

Completed

Single Rising Oral Doses of BI 1021958 in Healthy Chinese and Japanese Male Volunteers

Healthy

Korea, Republic of
RSPR Pharma AB

Completed

CRD007 for the Treatment of Abdominal Aorta Aneurysm (The AORTA Trial)

Abdominal Aortic Aneurysm

Sweden, United Kingdom, Denmark
Kubota Vision Inc.

Completed

Safety and Tolerability of ACU-4429

Healthy

United States
Addex Pharma S.A.

Completed

ADX10059 as a Monotherapy in Patients With Gastroesophageal Reflux (GERD)

Gastroesophageal Reflux

Austria, Belgium, France, Germany
Novartis Pharmaceuticals

Completed

Efficacy and Safety of LCZ696 Compared to Valsartan on Cognitive Function in Patients With Chronic Heart Failure and Preserved Ejection Fraction (PERSPECTIVE)

Chronic Heart Failure (CHF)

Spain, Croatia, Taiwan, Germany, Italy, United States, Australia, Netherlands, Switzerland, Belgium, United Kingdom, Bulgaria, Lithuania, Russian Federation, France, Argentina, Korea, Republic of, Poland, Canada, Turkey
ChemoCentryx
Medpace, Inc.

Completed

Controlled Trial Evaluating Avacopan in C3 Glomerulopathy (ACCOLADE)

C3 Glomerulopathy (C3G)

United States, Spain, France, Netherlands, Belgium, Canada, Denmark, Germany, Ireland, Italy, United Kingdom
Cognition Therapeutics
National Institute on Aging (NIA)

Active, not recruiting

A Study to Evaluate the Safety and Efficacy of CT1812 in Subjects With Mild to Moderate Alzheimer's Disease.

Mild to Moderate Alzheimer's Disease

United States, Australia, Netherlands, Czechia, Spain
9 Meters Biopharma, Inc.

Terminated

Study to Evaluate the Efficacy and Safety of Larazotide Acetate for the Relief of CeD Symptoms

Celiac Disease

United States
Daiichi Sankyo Co., Ltd.

Completed

Study of Mirogabalin for Central Neuropathic Pain

Central Neuropathic Pain

Japan, Korea, Republic of, Taiwan

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