Search clinical trials for: LPS infusion

Total 5390 results

University of Aberdeen

Completed

Whey Protein Study - Identification of Sustainable Satiety

Satiety

United Kingdom
Barmherzige Brüder Linz

Completed

Possible Links Between Inflammation and Lipid Metabolism

Sepsis | Inflammation | Lipid Metabolism Disorder | LPS

Austria
Rigshospitalet, Denmark

Recruiting

Combined Molecular Testing for Influenza, SARS-CoV-2, and RSV RNA From Different Upper Airway Specimens.

COVID-19 | Influenza | RSV Infection

Denmark
Ewha Womans University

Completed

Comparison of Nonposterior- and Posterior-Stabilized Mobile-Bearing Total Knee Arthroplasty

Osteoarthritis

Korea, Republic of
Radboud University Medical Center

Completed

the Influence of Remote Ischemic Preconditioning on Inflammation During Human Endotoxemia (RISPENDO)

Autoimmune Diseases | Infection

Netherlands
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Inflammation and the Metabolic Syndrome in Humans (LPS)

Metabolic Syndrome X

United States
Cochlear
Avania

Not yet recruiting

Investigating Stimulation Parameter and Electrode Mode Changes on Speech Perception in Experienced Adult Cochlear Implant Recipients (DUAL)

Hearing Loss, Sensorineural

Australia
The University of New South Wales

Completed

Faecal Microbiota Transplantation in Ulcerative Colitis (FOCUS)

Ulcerative Colitis | Inflammatory Bowel Disease

Australia
Ewha Womans University

Completed

Do We Need High-Flexing Total Knee Arthroplasty to Improve the Survivorship and to Decrease the Incidence of Osteolysis?

Osteoarthritis

Korea, Republic of
Yale University
National Institute on Aging (NIA)

Completed

Peripheral Benzodiazepine Receptors (PBR28) Brain PET Imaging With Lipopolysaccharide Challenge for the Study of Microglia Function in Alzheimer's Disease

Alzheimer Disease

United States
Centre Hospitalier Universitaire Brugmann

Unknown

Inflammatory Markers in Sputum After LPS Inhalation

Inflammation

Belgium
Imperial College London
GlaxoSmithKline

Completed

Nasal LPS Challenge in Healthy Volunteers

Healthy

United Kingdom
Medical University of Vienna

Completed

Ethnic Differences in the Inflammatory Response in Systemic Inflammation

Endotoxemia

Austria
Zimmer Biomet

Completed

A Study to Compare the NexGen LPS and LPS-Flex Knee Implants

Osteoarthritis | Total Knee Arthroplasty

United States, Canada
Laureate Institute for Brain Research, Inc.

Recruiting

Neural Response to Inflammatory Challenge in Major Depressive Disorder

Major Depressive Disorder

United States
University of Maryland, Baltimore

Withdrawn

Brain Biomarker on Inflammation Response (LPS)

Schizophrenia

United States
Yale University
National Institute of Mental Health (NIMH)

Active, not recruiting

Imaging the Neuroimmune System in PTSD

Post Traumatic Stress Disorder

United States
Alteco Medical AB

Withdrawn

Remove LPS Registry

Suspected or Diagnosed Endotoxemia Casued by Gram-negative Bacteria
Boehringer Ingelheim

Completed

Effect of BIBT 986 Followed by BIBT 986 Given as IV Infusion on Tissue Factor Triggered Coagulation in Healthy Male Volunteers

Healthy
Yale University

Completed

Neuroimmune Response to Lipopolysaccharide

Healthy

United States
Fraunhofer-Institute of Toxicology and Experimental...
Hannover Medical School

Completed

Development of Novel Non-invasive Inflammometry Following Lipopolysaccharide, Endotoxin (LPS) Challenge in Healthy Volunteers

Healthy

Germany
Radboud University Medical Center
UMC Utrecht

Completed

The Effects of Human Endotoxemia on Functional Capacity of Hematopoietic Stem and Progenitor Cells (LPS-BM)

Sepsis, Endotoxemia, Immunosuppression

Netherlands
Efferon JSC

Recruiting

Selective Lipopolysaccharide Hemosorption in Maternal Sepsis (MINERVA)

Maternal sepsIs

Russian Federation
Azienda Ospedaliera Cardinale G. Panico

Completed

Continuous Locked Non-barbed Suture for Mesh Fixation During Laparoscopic Ventral Rectopexy for Severe Rectal Prolapse

Rectal Prolapse
Radboud University Medical Center

Completed

The Effects of Preceding LPS Administration on the Fluenz-induced Immune Response (LPS-Fluenz)

Innate Immune Response | Immune Tolerance
National Jewish Health

Not yet recruiting

Nasal Inflammation Following Endotoxin Challenge in Patients With Asthma (Nasal-LPS)

Asthma | Asthma; Eosinophilic

United States
Ewha Womans University

Completed

A Gender-Specific Posterior Cruciate-Substituting High-Flexion Knee Prosthesis Does Not Improve Fit and Function

Female | Osteoarthritis of the Knee

Korea, Republic of
Osprey Pharmaceuticals USA, Inc.

Terminated

Safety Study of of Intravenous CCL2-LPM in Patients With IgA Nephropathy

Proteinuria | IGA Nephropathy

Canada
Karolinska Institutet
The Swedish Research Council; University of California, San Francisco; Swedish... and other collaborators

Completed

Inflammation and Brain Function - Main Study

Sickness Behavior
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Terminated

Range of Neutrophil Response to 20,000 EU of Clinical Center Reference Endotoxin in Otherwise Healthy Smokers

Healthy Smokers

United States
John Sundy

Terminated

Genetics of Asthma - Bronchoscopy Studies

Healthy | Atopic Asthma

United States
Imperial College London

Withdrawn

Endotoxin and Inflammatory Markers in Healthy Non-Smokers and Current Smokers Including Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United Kingdom
Karolinska Institutet
The Swedish Research Council; University of California, San Francisco; Swedish... and other collaborators

Completed

Inflammation and Brain Function - Pilot Study

Sickness Behavior
Alteco Medical AB
Uppsala University; TFS Trial Form Support

Terminated

ASSET - a Double-Blind, Randomized Placebo-Controlled Clinical Investigation With Alteco® LPS Adsorber (ASSET)

Septic Shock

Finland, Norway, Sweden
Zimmer Biomet

Withdrawn

LPS Flex Porous Femoral Components

Osteoarthritis | Rheumatoid Arthritis | Traumatic Arthritis | Collagen Disorders | Avascular Necrosis of Femoral Condyle | Poly Arthritis
Pfizer

Terminated

A Study To Evaluate The Safety And Effects On The Body Of An Investigational Drug Using An Endotoxin-Induced Inflammatory Response Model (POM)

Healthy

United States
Hvidovre University Hospital

Unknown

Comparing Clinical Outcome of 2 Different Total Knee Prostheses: Nexgen LPS-Flex Versus AGC

Osteoarthritis, Knee

Denmark
Patrick Wagner, MD, FACS
List Biological Laboratories, Inc

Recruiting

Feasibility Study of Intra-Tumoral Lipopolysaccharide Immunotherapy for Intra-Abdominal (LPS)

Abdominal Cancer | Malignancy

United States
Radboud University Medical Center

Completed

The Effects of Concentration/Meditation on the Innate Immune Response During Human Endotoxemia

Innate Immune Response

Netherlands
University of North Carolina, Chapel Hill
National Institute of Environmental Health Sciences (NIEHS)

Terminated

Response of Airway Cells to 20,000 EU of Endotoxin in Normal Adults

Healthy Controls

United States
Efferon JSC
Ligand Research, LLC

Completed

Lipopolisaccharide Adsorption at Septic Shock (LASSO)

Septic Shock

Russian Federation
Seoul National University Hospital

Unknown

Comparison of Outcomes in Mobile and Fixed-bearing Total Knee Arthroplasty

Osteoarthritis of Knee

Korea, Republic of
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of a 10,000 EU Dose of Endotoxin in Allergic and Mildly Asthmatic Adults

Asthma | Rhinitis, Allergic, Perennial | Rhinitis, Allergic, Seasonal

United States
Arizona Heart Institute

Unknown

Clinical Study of Abdominal Aortic Aneurysm Exclusion (TALENT Abdominal) (l)

Abdominal Aortic Aneurysm

United States
Radboud University Medical Center
Exponential Biotherapies Inc.

Completed

PK/PD of EA-230 During Endotoxemia

Endotoxemia | Systemic Inflammatory Response

Netherlands
Charite University, Berlin, Germany
German Research Foundation; adexter GmbH

Completed

Immunoadsorption of LPS, C5a and IL-6 in Severe Sepsis and Septic Shock (ISASS-1)

Septicemia

Germany
University of Aarhus

Completed

A Study of Intracellular Signaling in Muscle and Fat Cells During Ketosis

Diabetes Mellitus Type 1 | Ketoacidosis

Denmark
Karolinska Institutet
Danderyd Hospital

Completed

Endotoxin-induced Inflammatory and Behavioral Responses and Predictors of Individual Differences

Sickness Behavior
Radboud University Medical Center

Completed

Effects of Oxygen Status on Endotoxemia Induced Inflammation and Hypoxia Inducible Factor-1α

Hypoxia | Hyperoxia | Normoxia

Netherlands
Ottawa Hospital Research Institute
University of Ottawa

Recruiting

How TKA Implants Affect Muscle Quality and Activity During Daily Living and Immunological Response

Osteoarthritis, Knee | Inflammation Knees

Canada

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