Search clinical trials for: Lapaquistat acetate

Total 3961 results

Lexicon Pharmaceuticals

Completed

Phase 1, Open-label, Drug-drug Interaction Study With Octreotide Acetate Injection and Telotristat Etiprate in Healthy Subjects

Drug Interactions

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Octreotide in Preventing or Reducing Diarrhea in Patients Receiving Chemoradiotherapy for Anal or Rectal Cancer

Colorectal Cancer | Anal Cancer | Drug/Agent Toxicity by Tissue/Organ | Radiation Enteritis

United States
Ferring Pharmaceuticals

Terminated

A Degarelix Trial in Patients With Prostate Cancer

Prostate Cancer

United States, Netherlands, United Kingdom, Hungary, Belgium, Czech Republic, Finland, Germany, Mexico, Poland, Romania, Ukraine, Canada
Novartis Pharmaceuticals

Terminated

Extension Study of the Long-term Safety and Tolerability of Octreotide Acetate in Patients With Moderately Severe or Severe Non-proliferative Diabetic Retinopathy or Low Risk Proliferative Diabetic Retinopathy

Diabetic Retinopathy
Aldeyra Therapeutics, Inc.

Completed

A Safety and Efficacy Study of NS2 in Patients With Anterior Uveitis

Non-infectious Anterior Uveitis

United States
Bausch & Lomb Incorporated

Completed

Loteprednol vs Prednisolone for the Treatment of Intraocular Inflammation Following Cataract Surgery in Children.

Cataract

United States
Nantes University Hospital

Completed

Efficacy and Tolerance of Ultrasound-guided Needling and Lavage of Calcific Tendinitis of the Rotator Cuff Performed With or Without Subacromial Corticosteroid Injection (CALCECHO)

Calcifying Tendinitis of Shoulder

France
Bayer
RTI Health Solutions

Completed

Risk Minimisation Study for Diane-35 and Its Generics

Acne Vulgaris

France, Spain, Austria, Czech Republic, Netherlands
Indiana University School of Medicine

Completed

A Comparison of Three Different Formulations of Prednisolone Acetate 1%

Glaucoma | Cataract

United States
Paraskevi Matsota

Completed

A Comparative Study of Volume Replacement With HES 130/0.4 Versus Ringer's Lactate (RL) Regarding Their Effects on Inflammatory Biomarkers (Cytokines and Matrix Metalloproteinases) Responses to Major Abdominal Surgery.

Postoperative Inflammation

Greece
Organon and Co

Withdrawn

An Efficacy and Safety Study of Corifollitropin Alfa (MK-8962) in Contrast to Recombinant FSH for Use in Controlled Ovarian Stimulation of Indian Women (P07056, Also Known as MK-8962-029)

Infertility
Sidney Kimmel Cancer Center at Thomas Jefferson...
Astellas Pharma Inc; Medivation, Inc.

Active, not recruiting

Enzalutamide, Radiation Therapy and Hormone Therapy in Treating Patients With Intermediate or High-Risk Prostate Cancer

Recurrent Prostate Cancer | Stage III Prostate Cancer | Adenocarcinoma of the Prostate | Stage IV Prostate Cancer | Stage IIB Prostate Cancer

United States
Bayer

Completed

A Study to Learn About the Awareness and Knowledge That Doctors Have About the Safety and Safe Use Information for Androcur and Other Cyproterone Acetate Treatments in Europe (Safe-CAM)

Prostate Cancer | Signs of Androgenisation in Women, e.g. Hirsutism, Androgenetic Alopecia, Acne and Seborrhea | Hypersexuality in Men | Sexual Deviations in Men

Spain, Germany, Netherlands, Poland, France
Biocad

Completed

Efficacy and Safety of BCD-063 and Copaxone-Teva in Patients With Relapsing-Remitting Multiple Sclerosis

Relapsing-remitting Multiple Sclerosis
Bial - Portela C S.A.

Completed

Effect of Eslicarbazepine Acetate on the Pharmacokinetics of Gliclazide in Healthy Volunteers

Epilepsy

Portugal
Scott and White Hospital & Clinic

Unknown

Pretreatment With Norethindrone Acetate Prior to Levonorgestrel IUS Insertion for Heavy Menstrual Bleeding (Mirena IUD)

Menorrhagia | Heavy Menstrual Bleeding | Hypermenorrhea

United States
ORA, Inc.

Completed

Evaluation of the Efficacy of Topical Ophthalmic Steroids in a Modified Conjunctival Allergen Challenge (CAC) Model

Allergic Conjunctivitis

United States
Novartis Pharmaceuticals

Terminated

Extension Study of Long-term Safety and Tolerability of Octreotide Acetate in Patients With Moderately Severe or Severe Non-proliferative Diabetic Retinopathy or Low Risk Proliferative Diabetic Retinopathy

Diabetic Retinopathy
Ottawa Hospital Research Institute

Completed

Crystalloid FLUID Choices for Resuscitation of Hospital Patients (FLUID)

Fluid Therapy

Canada
Erasmus Medical Center
Albert Schweitzer Hospital; Sint Franciscus Gasthuis; Medical Center Rijnmond... and other collaborators

Completed

Early Lactate-Directed Therapy in the Intensive Care Unit (ICU)

Hyperlactatemia | Tissue Hypoxia

Netherlands
Children's Hospital of Fudan University

Completed

Clinical Trial of Rapid Progressive Central Precocious Puberty With Integrative Chinese and Western Medicine

Idiopathic Precocious Puberty

China
Sight Medical Doctors PLLC
Ocular Therapeutix, Inc.

Completed

Intracanalicular Dexamethasone Insert for Post-Corneal Cross-Linking Inflammation and Pain- The LINK Study

Postoperative Pain | Keratoconus, Unstable | Collagen Crosslinking

United States
Wyse Eyecare

Enrolling by invitation

A Study for Post op Inflammation After Cataract Surgery

Cataract

United States
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

A Trial of SHR3162 Combined With Apatinib Mesylate Tablets or SHR3162 Monotherapy in Patients With Metastatic Castration Resistant Prostate Cancer

Metastatic Castration Resistant Prostate Cancer

China
Lakehead University

Unknown

Calcific Tendinitis: Comparing Minimally Invasive Modalities

Calcific Tendinitis

Canada
Endo Pharmaceuticals
Quintiles, Inc.

Completed

Evaluate Weight Gain Using 2 Different Formulations of Megestrol Acetate Oral Suspension for AIDS-related Weight Loss

HIV Infections | Anorexia | Cachexia | HIV Wasting Syndrome | AIDS Wasting Syndrome

United States, India, South Africa
Kwong Wah Hospital

Completed

Efficacy Study of Local Steroid Injection and Wrist Splinting for Carpal Tunnel Syndrome

Carpal Tunnel Syndrome | Local Steroid Injection | Wrist Splinting

China
Cornea Research Foundation of America

Completed

Comparison of Corticosteroid Dosing Regimens After Endothelial Keratoplasty

Corneal Edema | Fuchs' Dystrophy

United States
Alcon Research

Completed

Safety and Efficacy of Difluprednate 0.05% for the Treatment of Anterior Uveitis

Endogenous Anterior Uveitis

United States
Teva Pharmaceuticals USA

Completed

Estradiol/Norethindrone Acetate Tablets, 1/0.5 mg Under Fed Conditions

Healthy

Canada
Oncotherapeutics
Amgen

Terminated

Weekly 70 mg/m2 Carfilzomib for Multiple Myeloma Patients Refractory to 27 mg/m2 Carfilzomib

Multiple Myeloma

United States
Federal University of São Paulo
Allergan

Completed

Non-Inferiority of Gatifloxacin/Prednisolone Association vs Isolated Administration in Prevention of Ocular Infection/Inflammation

Ocular Infection and Inflammation

Brazil
Merck Sharp & Dohme LLC

Completed

Clinical Trial of Ridaforolimus Compared to Progestin or Chemotherapy for Advanced Endometrial Carcinoma (MK-8669-007 AM6)

Endometrial Cancer
Symetis SA

Completed

ACURATE TA™ Valve Implantation Registry: SAVI 2 (TA-SAVI2)

Aortic Stenosis

Germany, Austria, Italy, Switzerland
Nepean Blue Mountains Local Health District
Innogene Kalbiotech Pte. Ltd

Completed

0.5M Na Lactate Solution in Acute Heart Failure (AHF) (SOLACE1)

Acute Heart Failure

Australia
AstraZeneca

Completed

Comparative Study of Oestradiol Suppression: Zoladex 10.8mg/3 Month vs. 3.6mg/Month in ER +ve EBC Pre-menopausal Patients

Breast Cancer

Japan
Pfizer
Astellas Pharma Inc

Active, not recruiting

A Study to Learn About the Study Medicines Called Enzalutamide and Abiraterone in People With Metastatic Castration-resistant Prostate Cancer

Prostatic Neoplasms, Castration-Resistant

United States
Sunovion

Completed

A Study of a Drug to be Used in Addition With Another Drug to Treat Adults With Uncontrolled Partial-onset Seizures

Epilepsy With Partial On-set Seizures

United States, Canada
AbbVie

Completed

Efficacy and Safety Study of Elagolix Versus Placebo or Leuprorelin Acetate in Endometriosis

Endometriosis
Aurelius Omlin
University Hospital, Basel, Switzerland; Cantonal Hospital of St. Gallen

Terminated

Abiraterone-Rechallenge Study for CRPC Patients (ABI-RE)

Prostate Cancer

Switzerland
Cancer Research UK

Completed

Abiraterone Acetate in Treating Postmenopausal Women With Advanced or Metastatic Breast Cancer

Breast Cancer

United Kingdom
Alkeus Pharmaceuticals, Inc.

Completed

Phase 1 Safety Study of ALK-001 in Healthy Volunteers

Age-related Macular Degeneration | Stargardt Disease | Other Retinal Dystrophies
Mansoura University

Completed

Efficacy of LNG-IUS for Treatment of Non-atypical Endometrial Hyperplasia in Perimenopausal Women

Endometrial Hyperplasia

Egypt
Windtree Therapeutics
Momentum Research, Inc.

Not yet recruiting

A Safety and Efficacy Trial of Istaroxime for Cardiogenic Shock Stage C (SEISMiC-C)

Cardiogenic Shock
International Centre for Diarrhoeal Disease Research...

Recruiting

Saving Lives by Early Detection and Treatment of Sepsis and Septic Shock by Point of Care Lactate Test in Adults (POCLactate)

Lactate Blood Increase | Severe Sepsis With Septic Shock

Bangladesh
First Affiliated Hospital, Sun Yat-Sen University

Completed

Effects of Continuous Veno-venous Haemofiltration on Plasma Lactate in Critically Ill Patients

Kidney Injury, Acute

China
Radboud University Medical Center

Unknown

The Effect Lactate Administration on Cerebral Blood Flow During Hypoglycemia

Type1diabetes | Hypoglycemia Unawareness

Netherlands
Medical University of Vienna

Completed

Goal Directed Fluid Therapy (FLO1)

Goal Directed Fluid Therapy

Austria
Universitas Padjadjaran

Completed

Effect of Exogenous Lactate on Neurocognitive in Brain Trauma

Traumatic Brain Injury

Indonesia
Alexandria University

Completed

Supplemental Perioperative Intravenous Crystalloids for Postoperative Nausea and Vomiting in Children Undergoing Oncological Surgery

Nausea and Vomiting, Postoperative

Egypt

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