Search clinical trials for: MK-0249 7.5 mg

Total 1133 results

Merck Sharp & Dohme LLC

Active, not recruiting

Pembrolizumab (MK-3475) Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630)

Carcinoma, Squamous Cell

Ukraine, United States, Argentina, Australia, Brazil, Canada, Chile, Colombia, France, Germany, Greece, Hungary, Ireland, Israel, Italy, Mexico, New Zealand, Norway, Poland, Portugal, Romania, Russian Federation, Spain, United Kingdom
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

Phase IIb Study of Evobrutinib in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Serbia, Ukraine, United States, Czechia, Poland, Argentina, Mexico, South Africa, Chile, Bulgaria, Colombia, Russian Federation
FAST BioMedical
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Completed

FAST GFR: Pilot Study to Evaluate the Safety of the FAST GFR Test in Patients.

Chronic Kidney Disease | Acute Kidney Injury

United States
GL Pharm Tech Corporation

Unknown

The Pharmacokinetics of GLA5PR Tablet According to the Renal Function

Neuropathic Pain

Korea, Republic of
Merck Sharp & Dohme LLC

Completed

Dose Response Finding Study of MK-0431/ONO-5435 in Japanese Subjects With Impaired Glucose Tolerance (MK-0431-105)

Glucose Intolerance
Pfizer

Terminated

Study Comparing 3 Dosage Levels Of SAM-531 In Outpatients With Mild To Moderate Alzheimer Disease

Alzheimer Disease

United States, Colombia, Korea, Republic of, Russian Federation, Japan, Hong Kong, South Africa, Poland, Chile, Romania, Mexico, Argentina, New Zealand
Immodulon Therapeutics Ltd
Theradex; HCA International Limited

Completed

A Clinical Study, to Evaluate the Safety and Tolerability of Intradermal IMM-101 in Adult Melanoma Cancer Patients

Melanoma

United Kingdom
Chengdu Kanghong Biotech Co., Ltd.

Terminated

Efficacy and Safety Trial of Conbercept Intravitreal Injection for Neovascular AMD (PANDA-1)

Neovascular Age-related Macular Degeneration

United States, Argentina, Australia, Austria, Belgium, Canada, Chile, Colombia, Germany, Hong Kong, Lithuania, Mexico, Netherlands, New Zealand, Peru, Philippines, Poland, Portugal, Singapore, Spain, Switzerland, Taiwan
Chengdu Kanghong Biotech Co., Ltd.

Terminated

Efficacy and Safety Trial of Conbercept Intravitreal Injection for Neovascular AMD (PANDA-2)

Neovascular Age-related Macular Degeneration

United States, Bulgaria, China, Czechia, Denmark, France, Hungary, Israel, Italy, Latvia, Slovakia, United Kingdom
University of the Ryukyus

Completed

Dose-finding Study of Colchicine in Type 2 Diabetic Patients With Coronary Artery Disease (DRC-04)

Coronary Artery Disease | Inflammation | Diabetes Mellitus, Type 2 | Diarrhea | Colchicine | White Blood Cell

Japan
Pfizer

Completed

Long Term Safety and Efficacy Study of Tanezumab in Subjects With Osteoarthritis of the Hip or Knee

Chronic Pain | Osteoarthritis, Knee | Osteoarthritis, Hip

United States, Korea, Republic of, Taiwan, Australia, Serbia, Japan, New Zealand, Philippines, Lithuania, Russian Federation, Croatia, Brazil, Bulgaria, Slovakia, Colombia, Mexico, Peru, Ukraine
Pharmtechnology LLC

Recruiting

Bioequivalence Study of Perindopril /Amlodipine/Indapamide 8 mg (10 mg)/2.5 mg/10 mg Tablets in Healthy Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation
Joseph Hazelton

Completed

A Double-Blind, Randomized, Active- and Placebo-Controlled, Multiple-Dose Multi-Center Phase 3 Study of the Safety and Efficacy of CL-108 in the Treatment of Moderate to Severe Acute Pain and Opioid-Induced Nausea and Vomiting (OINV)

Pain | Nausea | Vomiting

United States
Gazi University

Completed

Comparing the Effects of Levobupivacaine and Bupivacaine in Saddle Spinal Anesthesia

Drug Effect | Anesthesia | General Surgery | Outpatients | Anorectal Disorder
Janssen Korea, Ltd., Korea

Completed

A Study to Assess the Bioequivalence of a New ULTRACET Extended Release (ER) Tablet With Respect to a Marketed ULTRACET ER Tablet Under Fasted Condition

Healthy

Korea, Republic of
Spanish Oncology Genito-Urinary Group
Apices Soluciones S.L.; Janssen, LP

Completed

Abiraterone Acetate in Combination With Docetaxel After Disease Progression to Abiraterone Acetate in Metastatic Castration Resistant Prostate Cancer. (ABIDO)

Metastatic Prostate Cancer

Spain
Grifols Therapeutics LLC

Completed

A Dose Escalation and Safety Study of Plasmin (Human) In Acute Lower Extremity Native Artery or Bypass Graft Occlusion (PRIORITY)

Arterial Occlusive Diseases

United States
Abbott

Completed

A 12-week Study to Compare the Efficacy and Safety of Fixed Combinations of Fenofibrate/Simvastatin 145/20mg and Fenofibrate/Simvastatin 145/40mg Tablets Versus Fenofibrate or Simvastatin Monotherapies in Subjects With Abnormal Blood Levels of Fats (Lipids) and at High Risk of Cardiovascular Disease

Dyslipidemia

Argentina, Czech Republic, Germany, Mexico, Poland, Romania, Russian Federation
H. Lundbeck A/S

Completed

Comparative Study of the Pharmacokinetics and Bioequivalence of Two Flupentixol Formulations

Bioequivalence Study in Healthy Subjects

Russian Federation
AbbVie

Withdrawn

A Study To Assess Adverse Events and Change in Disease Activity With Oral Cariprazine When Added to Antidepressant Therapies (ADTs) Compared to Placebo in Adult Participants With Generalized Anxiety Disorder (GAD) Who Have Had an Inadequate Response to ADTs Alone (CAR aGAD Ph 2)

Generalized Anxiety Disorder

United States
Chong Kun Dang Pharmaceutical

Completed

The Pharmacokinetic Interaction Between CKD-501 and Sulfonylurea (CKD-501 DDI)

Healthy Male Volunteer

Korea, Republic of
Merck Sharp & Dohme LLC

Completed

A Trial of Pembrolizumab (MK-3475) in Participants With Blood Cancers (MK-3475-013/KEYNOTE-013)

Follicular Lymphoma | Diffuse Large B-Cell Lymphoma | Multiple Myeloma | Hodgkin Lymphoma | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Primary Mediastinal B-Cell Lymphoma
Novo Nordisk A/S

Completed

Bleed Free Treatment of Menopausal Symptoms With New Ultra Low Dose Hormonal Combinations (CHOICE)

Menopause | Menopausal Vasomotor Symptoms

Denmark, United Kingdom, Sweden, Belgium, Switzerland, Germany, France, Finland, Austria, Norway
Kati Järvelä
Finnish Cultural Foundation

Completed

Effects of Hypertonic Saline-HES Solution on Extracellular Water in Cardiac Surgery Patients

Fluid Volume Disorder

Finland
GlaxoSmithKline

Completed

Bioequivalence - Duodart Against Avodart & Omnic

Prostatic Hyperplasia

Russian Federation
Novartis Pharmaceuticals

Completed

Systemic Vascular Endothelial Growth Factor (VEGF) Protein Dynamics Following Intravitreal Injections of Ranibizumab Versus Aflibercept in Patients With Neovascular Age-related Macular Degeneration (TIDE AMD)

Wet Age-Related Macular Degeneration

Germany
Eli Lilly and Company

Completed

Study of Tadalafil Once-a-Day for 12 Weeks in Japanese Men With Benign Prostatic Hyperplasia Followed by an Open-Label Extension

Benign Prostatic Hyperplasia

Japan
Merck Sharp & Dohme LLC
Duke Clinical Research Institute; The TIMI (Thrombolysis in Myocardial Infarction)...

Completed

Trial to Assess the Ocular Safety of Vorapaxar (SCH 530348) in Participants With Atherosclerosis (Study P05183)

Myocardial Infarction | Ischemia | Atherosclerosis | Cerebrovascular Accident
Peking University First Hospital

Unknown

A Study in Reversing Hepatic Fibrosis or Cirrhosis Related to Hepatitis B Virus and Finding Biomarkers

Hepatitis B | Liver Fibrosis

China
Novartis Pharmaceuticals

Completed

A Comparison of Ranibizumab and Aflibercept for the Development of Geographic Atrophy in (Wet) AMD Patients (RIVAL)

Age-Related Macular Degeneration

Australia
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Bioequivalence Study of 3 New Formulations of Premarin/MPA Compared With Premarin/MPA (Prempro)

Postmenopause

United States
AB Science

Recruiting

Masitinib for the Treatment of Severe Mast Cell Activation Syndrome

Mast Cell Activation Syndrome

France, United States
Novartis Pharmaceuticals
European and Developing Countries Clinical Trials Partnership (EDCTP); Medicines... and other collaborators

Active, not recruiting

Pharmacokinetics, Safety, Tolerability and Efficacy of a New Artemether-lumefantrine Dispersible Tablet in Infants and Neonates <5 kg Body Weight With Acute Uncomplicated Plasmodium Falciparum Malaria (CALINA)

Plasmodium Falciparum Malaria

Burkina Faso, Congo, The Democratic Republic of the
Novartis

Completed

Safety and Efficacy of Ranibizumab in Diabetic Macular Edema With Center Involvement (RESOLVE)

Diabetic Macular Edema

Switzerland
Novartis

Completed

Efficacy and Safety of Ranibizumab in Patients With Subfoveal Choroidal Neovascularization (CNV) Secondary to Age-related Macular Degeneration (AMD) (EXCITE)

Age Related Macular Degeneration

Switzerland
Akros Pharma Inc.

Completed

Safety and Efficacy Study of JTT-705 in Combination With Simvastatin 40 mg in Patients With Low High-Density Lipoprotein (HDL) Levels

Dyslipidemia

Netherlands
Akros Pharma Inc.

Completed

Safety and Efficacy Study of JTT-705 in Combination With Atorvastatin 20 mg in Patients With Low High-Density Lipoprotein (HDL) Levels

Dyslipidemia

Netherlands
University of Texas Southwestern Medical Center
GlaxoSmithKline

Recruiting

Phase 1/2a Study of Belantamab Mafodotin in Relapsed or Refractory AL Amyloidosis

AL Amyloidosis | Amyloidosis

United States
Merck Sharp & Dohme LLC

Completed

Trial to Assess the Safety of Vorapaxar in Japanese Subjects With Cerebral Infarction (P05005; MK-5348-017)

Cerebral Infarction
Labopharm Inc.

Completed

A Comparative Bioavailability/Food Effect Study of Immediate-Release and Extended-Release Tramadol HCl/Acetaminophen Combination Products Following Single-Dose and Multiple-Dose Administration in Healthy Adult Volunteers

Healthy

United Kingdom
Alexza Pharmaceuticals, Inc.

Completed

Staccato Loxapine Single Dose PK

Schizophrenia

United States
Sumitomo Pharma Co., Ltd.

Completed

A Pharmacodynamics and Safety Study of DSP-9632P in Patients With Levodopa-Induced Dyskinesia in Parkinson's Disease

Parkinson's Disease | Levodopa-induced Dyskinesia

Japan
Afferent Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Effect of Gefapixant (AF-219/MK-7264) on Methacholine Hyper-reactivity in Participants With Asthma (MK-7264-009)

Asthma
Boehringer Ingelheim
Eli Lilly and Company

Completed

Relative Bioavailability of 2 Fixed Dose Combinations of Linagliptin/Metformin Compared With Single Tablets

Healthy

United States
Instituto de Investigación Sanitaria Aragón
Hospital Miguel Servet

Completed

Diaphragmatic Paralysis Comparison Between Local Anesthetic Volumen Doses After Interscalene Block (REDOLEV-2019)

Brachial Plexus Block | Diaphragmatic Paralysis

Spain
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Letrozole Tablets 2.5 mg and Femara® Tablets 2.5 mg

Healthy

United States
Thomas Schricker
Merck Sharp & Dohme LLC

Terminated

Surgical Conditions During Vocal Cord Surgery Requiring Jet Ventilation With Moderate vs. Deep Neuromuscular Block

High-Frequency Jet Ventilation | Vocal Cord Resection

Canada
Merck Sharp & Dohme LLC

Completed

Study of the Safety, Tolerability, and Efficacy of Relebactam (MK-7655) + Imipenem/Cilastatin Versus Imipenem/Cilastatin Alone to Treat Complicated Intra-Abdominal Infection [cIAI] (MK-7655-004)

Intra-abdominal Infections
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Effect of MK-8669 (Ridaforolimus) on QTc Interval in Participants With Advanced Cancer (MK-8669-037)

Metastatic or Locally Advanced Cancer
Mylan Pharmaceuticals Inc

Completed

Food Study of Letrozole Tablets 2.5 mg and Femara® Tablets 2.5 mg

Healthy

United States

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