Search clinical trials for: MK-2048A IVR (Original Dose)

Total 294 results

National Institute of Allergy and Infectious Diseases...

Completed

Pharmacokinetics of Two Intravaginal Rings (IVRs) Containing Different Dose Strengths of Vicriviroc (MK-4176) and MK-2048

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Pharmacokinetics of Intravaginal Rings Containing Vicriviroc (MK-4176) and/or MK-2048

HIV Infections

United States
Hillier, Sharon, PhD
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Safety and Pharmacokinetics of Two Vaginal Film Formulations Containing the Integrase Inhibitor MK-2048 (FAME103)

Pharmacokinetics | Safety

United States
BioNTech SE
Pfizer

Withdrawn

A Study to Learn About Bivalent COVID-19 RNA Vaccine Candidate(s) in Healthy Infants and Children

COVID-19
Merck Sharp & Dohme LLC

Withdrawn

A Single-Dose Study of MK-8351 in a Lung Allergen Challenge (MK-8351-003)

Asthma
Merck Sharp & Dohme LLC

Completed

Polysomnography Study of MK-6096 in Participants With Primary Insomnia (MK-6096-011)

Primary Insomnia
New Jersey Institute of Technology
Kessler Foundation; Rutgers University; Northeastern University

Recruiting

Robot Assisted Virtual Rehabilitation for the Hand Post Stroke (RAVR) (RAVR)

Stroke, Acute

United States
Daré Bioscience, Inc.

Completed

Study of DARE-HRT1 Over 12 Weeks in Healthy PostMenopausal Women (DARE-HRT1)

Vasomotor Symptoms | Vulvovaginal Atrophy

Australia
BioNTech SE
Pfizer

Recruiting

A Study to Learn About Variant-Adapted COVID-19 RNA Vaccine Candidate(s) in Healthy Children

COVID-19 | Severe Acute Respiratory Syndrome Coronavirus 2 | SARS-CoV-2 Virus

United States, South Africa, Brazil, Puerto Rico
Beijing Bozhiyin T&S Co., Ltd.

Unknown

To Evaluate the Efficacy and Safety of Wenxin Keli in Treating Atrial Premature Beats

Atrial Premature Beats

China
Daré Bioscience, Inc.

Completed

A Phase 1, Open-Label, Parallel Group Study to Evaluate the Pharmacokinetics and Safety of DARE-HRT1 in Healthy PostMenopausal Women

Vasomotor Symptoms | Vulvovaginal Atrophy

Australia
Merck Sharp & Dohme LLC

Terminated

A Dose Exploration Study With Birabresib (MK-8628) in Participants With Selected Hematologic Malignancies (MK-8628-005)

DLBCL | AML Including AML de Novo and AML Secondary to MDS
Rockefeller University
Brigham and Women's Hospital; Weill Medical College of Cornell University; University...

Completed

A Phase 1, Open Label, Dose-escalation Study of the Safety, Pharmacokinetics and Antiretroviral Activity of 3BNC117

Healthy | HIV

United States, Germany
Basilea Pharmaceutica

Completed

Safety, Pharmacokinetics, Bioavailability, Food Effect, Drug-Drug Interaction Study of APX001 Administered Orally

Fungal Infection

Netherlands
Biogen

Completed

Phase 1 Study to Evaluate the PK, Safety, Tolerability of BIIB023 in Chinese, Japanese, and Caucasian Healthy Volunteers

Healthy Volunteers

Australia, China
Bioxodes S.A.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Ir-CPI in Healthy Male Subjects

Healthy

Belgium
Ablynx

Completed

Caplacizumab Single and Multiple Dose Study in Healthy Japanese and White Subjects.

Healthy Volunteers

United States
Vir Biotechnology, Inc.

Terminated

A Phase 2 Study to Evaluate the Efficacy and Safety of VIR-2482 for the Prevention of Illness Due to Influenza A

Influenza A

United States
Washington University School of Medicine
Case Western Reserve University; University of Health and Allied Sciences

Completed

Safety and Efficacy of IDA for Onchocerciasis (DOLF IDA/Oncho)

Onchocerciasis

Ghana
Merck Sharp & Dohme LLC

Completed

Relative Bioavailability Study of Subcutaneous Injection Versus Intravenous Infusion of Pembrolizumab (MK-3475) in Participants With Advanced Melanoma (MK-3475-555/KEYNOTE-555)

Melanoma

Australia, South Africa, Spain, Sweden
Prometheus Biosciences, Inc., a subsidiary of Merck...
Altasciences Company Inc.

Completed

Bioavailability of SC Formulation and Japanese Ethnobridging Study for PRA023

Healthy

United States
First Affiliated Hospital Xi'an Jiaotong University
Eureka Therapeutics Inc.

Unknown

ET190L1-ARTEMIS™ T Cells in Relapsed, Refractory B Cell Leukemia and Lymphoma

CD19+ Lymphoma, B-Cell | CD19+ Leukemia, B-Cell

China
Afferent Pharmaceuticals, Inc.

Completed

A 12-Week Study in Participants With Refractory Chronic Cough (MK-7264-012)

Refractory Chronic Cough
GlaxoSmithKline

Completed

A Study to Investigate the Safety Tolerability Pharmacokinetics, and Pharmacodynamics of Inhaled and Intravenous GSK2862277 in Healthy Volunteers

Respiratory Disorders

United Kingdom
Abdul El-Rabbany

Recruiting

Antibiotics for Prevention of Infection Following Orthognathic Surgery

Orthognathic Surgical Site Infection

Canada
James Larner, MD

Completed

HDCRT Plus Pembrolizumab in Advanced Malignancies (UVA-AM-001)

Solid Tumor

United States
Memorial Sloan Kettering Cancer Center

Completed

Image-Guided Navigation for High Dose Rate Temporary Interstitial Brachytherapy in the Palliative Management of Previously Treated Tumors of the Spine and Pelvis

Metastatic or Recurrent Lesions in the Spine | Metastatic or Recurrent Lesions in the Pelvis

United States
Kowa Research Institute, Inc.

Completed

Study to Investigate the Efficacy and Pharmacokinetic Profile of K-877-ER Compared to K-877-IR

Dyslipidemia

United States
GlaxoSmithKline

Completed

A Single Dose Pharmacokinetics (PK) Study of GSK2434735 in Healthy Male Volunteers

Asthma

United Kingdom
Locus Biosciences
Parexel

Recruiting

A Study of LBP-EC01 in the Treatment of Acute Uncomplicated UTI Caused by Drug Resistant E. Coli (ELIMINATE Trial) (ELIMINATE)

Urinary Tract Infections

United States
Merck Sharp & Dohme LLC

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

Crohn's Disease
Merck Sharp & Dohme LLC
PPD, Part of Thermo Fisher Scientific

Recruiting

A Study to Evaluate Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderately to Severely Active Ulcerative Colitis (MK-7240-001)

Ulcerative Colitis

United States, Israel, Japan, Korea, Republic of, Switzerland, Chile, Dominican Republic, Canada, Netherlands
Rockefeller University
University of Cologne

Completed

A Study of the Safety, Pharmacokinetics and Antiretroviral Activity of 10-1074

Healthy | HIV

Germany, United States
Merck Sharp & Dohme LLC

Completed

An Efficacy and Safety Study of Grazoprevir (MK-5172) + Elbasvir (MK-8742) in the Treatment of Chronic Hepatitis C Virus in Participants Who Are Co-Infected With Human Immunodeficiency Virus:C-EDGE CO-INFXN (MK-5172-061)

Chronic Hepatitis C
Celularity Incorporated

Terminated

Natural Killer Cell (CYNK-001) IV Infusion or IT Administration in Adults With Recurrent GBM (CYNK001GBM01)

Glioblastoma Multiforme | Molecular Mechanisms of Pharmacological Action | Giant Cell Glioblastoma | Astrocytoma, Grade IV | Physiological Effects of Drugs | Peripheral Nervous System Agents | Analgesics | Analgesics, Non-narcotic | Cyclophosphamide | Immunosuppressive Agents | Immunologic Factors | Antiviral... and other conditions

United States
Bayer

Completed

A Study to Learn How the Study Treatment BAY3283142 Taken as Single Dose by Mouth Moves Into, Through, and Out of the Body, How Safe it is, and How it Affects the Body in Participants With Reduced Kidney Function Compared to Participants With Normal Kidney Function of Similar Age, Gender, and Weight

Renal Impairment | Chronic Kidney Disease | Healthy Volunteers

Germany
Janssen Research & Development, LLC

Completed

Study of Guselkumab and Ustekinumab Following a Single Intravenous or Subcutaneous Administration in Healthy Chinese Participants

Healthy

China
AGC Biologics S.p.A.

Completed

A Modified Phase I Study of NGR-hTNF in Advanced Solid Tumors

Advanced Solid Tumors

Italy
Melinta Therapeutics, Inc.

Completed

Drug-Drug Interaction Potential of Orbactiv (Oritavancin) Co-Administered With Warfarin in Healthy Subjects

Healthy

United States
Prana Biotechnology Limited

Completed

Absorption, Metabolism and Excretion Study of [14C]PBT2 and Absolute Bioavailability of PBT2

Healthy Volunteers

United Kingdom
Suzanna L Attia
Fogarty International Center of the National Institute of Health

Completed

Nutritional Impact of Moringa Oleifera Leaf Supplementation in Mothers and Children

Malnutrition | Wasting | Growth Failure

Kenya
GlaxoSmithKline

Completed

A Study to Determine the Excretion Balance and Pharmacokinetics of 14C-GSK573719

Pulmonary Disease, Chronic Obstructive

Netherlands
Far Eastern Memorial Hospital

Completed

Different Dose of Intravenous Omeprazole to Treat Bleeding Ulcer With Adherent Clot

Hemorrhage | Peptic Ulcer

Taiwan
Universitätsklinikum Hamburg-Eppendorf

Completed

Hamburg Edoxaban for Anticoagulation in COVID-19 Study (HERO-19)

Covid19

Germany
National and Kapodistrian University of Athens

Unknown

Single Dose of Tranexamic Acid and Blood Loss, in Elderly Patients With Hip Fracture

Hip Fractures | Blood Loss, Surgical | Complication, Postoperative

Greece
Prolong Pharmaceuticals

Recruiting

Safety Study of PP-007 in Subjects With Acute Ischemic Stroke (HEMERA-1)

Acute Ischemic Stroke

United States
Naurex, Inc, an affiliate of Allergan plc

Terminated

Open Label Extension for GLYX13-C-202, NCT01684163

Major Depressive Disorder

United States
American Heart Association

Completed

Improving Outcomes In Diabetic Patients During CABG Surgery By Optimizing Glycemic Control

Glycemic Control

United States
Genuine Research Center, Egypt
Hikma Pharmaceuticals LLC

Completed

Bioequivalence Study of Budesonide From Ekmasonid 9 mg Extended Release FCT (Hikma Pharma, Egypt) Versus Uceris 9 mg Extended Release Tablets (Man. for: Salix Pharm., a Division of Valeant Pharm. LLC, USA, by: Cosmo S.P.A., Italy by License of Cosmo Tech. Ltd., Ireland, Product of France)

Healthy

Egypt
Murdoch Childrens Research Institute
Royal Children's Hospital

Recruiting

Single Dose Intravenous Antibiotics for Complicated Urinary Tract Infections in Children (CHOICE UTI)

Infection | Pediatric Infectious Disease | Complicated Urinary Tract Infection

Australia, New Zealand

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