Search clinical trials for: MK0653A, ezetimibe (+) simvastatin

Total 929 results

Abbott

Completed

A 12-week Study to Compare the Efficacy and Safety of Fixed Combinations of Fenofibrate/Simvastatin 145/20mg and Fenofibrate/Simvastatin 145/40mg Tablets Versus Fenofibrate or Simvastatin Monotherapies in Subjects With Abnormal Blood Levels of Fats (Lipids) and at High Risk of Cardiovascular Disease

Dyslipidemia

Argentina, Czech Republic, Germany, Mexico, Poland, Romania, Russian Federation
Solvay Pharmaceuticals

Completed

Interaction Study SLV337/Simvastatin

Type 2 Diabetes Mellitus

United Kingdom
Hotel Dieu de France Hospital
Pharmaline, Lebanon

Completed

Effect of Ezetimibe on Oxidized Low-density Lipoprotein (LDL) Cholesterol

Coronary Artery Disease | Diabetes

Lebanon
AstraZeneca

Completed

A Study to Assess Co-Administered AZD9056 (Steady State) and Simvastatin (Single Dose) in Healthy Volunteers

Healthy Volunteers

Germany
Organon and Co

Completed

Retrospective Survey Evaluating the Effectiveness and Safety of Dual Inhibition Lipid-lowering in the Treatment of Dyslipidemia (Study P05171)(COMPLETED)

Dyslipidemia
Organon and Co

Terminated

Investigational Drug in Patients With Hypercholesterolemia or in Patients With Sitosterolemia (0653-026)(COMPLETED)

Lipid Metabolism, Inborn Errors | Hypercholesterolemia, Familial
Indiana University

Withdrawn

The Influence of Ezetimibe on Gallbladder Function

Chronic Acalculous Cholecystitis

United States
Radiant Research

Completed

Ezetimibe Reverse Cholesterol Transport (RCT) Pilot Study

Hypercholesterolemia

United States
Sanofi

Completed

A Study Evaluating the Safety and Efficacy of AVE5530 (4 Weeks) in Patients With Mild to Moderate Hypercholesterolemia

Hypercholesterolemia

Russian Federation, Turkey, Mexico, Hungary, Korea, Republic of, Chile
University of Sao Paulo
Merck Sharp & Dohme LLC

Unknown

Evaluation of Chylomicrons Metabolism in Sub-Clinical Atherosclerosis in Patients Whit Heterozigous Familial Hypercholesterolemia (FH) Treated With Statin Plus Ezetimibe

Heterozigous Familial Hypercholesterolemia

Brazil
Daewoong Pharmaceutical Co. LTD.

Recruiting

Study to Evaluate the Management Status of Dyslipidemia Following Administration of Statin and Ezetimibe Complex Treatment Patient

Dyslipidemias

Korea, Republic of
Abbott

Completed

Safety and Efficacy Study Comparing ABT-335 Coadministered With Atorvastatin and Ezetimibe to Atorvastatin Coadministered With Ezetimibe in Subjects With Multiple Abnormal Lipid (Fat) Levels in the Blood

Dyslipidemias | Coronary Heart Disease | Mixed Dyslipidemia | Combined (Atherogenic) Dyslipidemia

United States
Cairo University
Aswan Heart Centre

Recruiting

Ezetimibe Utilization Early After Acute Myocardial Infarction, "EzAMI Trial" (EzAMI)

Dyslipidemias | Acute Myocardial Infarction

Egypt
Novartis

Completed

Efficacy and Safety Study of Fluvastatin and Ezetimibe Combined Versus Fluvastatin Alone

Dyslipidemia

Spain
Novartis Pharmaceuticals

Recruiting

Efficacy and Safety of Inclisiran as Monotherapy in Patients With Primary Hypercholesterolemia Not Receiving Lipid-lowering Therapy. (V-Mono)

Hypercholesterolemia

United States, Hungary, Mexico, Germany, Colombia
Helsinki University Central Hospital
University of Helsinki; Academy of Finland

Completed

Donor Simvastatin Treatment in Organ Transplantation (SIMVA)

Liver Failure | Heart Failure | Respiratory Failure | Kidney Failure | Transplantation

Finland
Steno Diabetes Center Copenhagen
Department of Clinical Physiology, Nuclear Medicine and PET at Rigshospitalet... and other collaborators

Active, not recruiting

Kidney Fat in Type 2 Diabetes and the Effects of Ezetimibe (DiaKidZ)

Diabetes Mellitus, Type 2 | Diabetic Kidney Disease

Denmark
University of Copenhagen

Unknown

Living With Statins - Interventional Exercise Study (LIFESTAT)

Cardiovascular Disease | Diabetes Mellitus

Denmark
Azienda Ospedaliero Universitaria di Sassari

Unknown

Ezetimibe/Simvastatin Combination in Proteinuric Nephropathy (VICTORY)

Hypercholesterolemia | Chronic Nephropathy

Italy
Organon and Co

Completed

A Study to Evaluate the Effects of Ezetimibe (MK-0653) on the Postprandial (Following a Meal) Lipoprotein Response in Participants With Primary Hypercholesterolemia (High Cholesterol) (MK-0653-072)(COMPLETED)

Hypercholesterolemia
Judit Pich

Completed

Simvastatin Plus Rifaximin in Decompensated Cirrhosis (LIVERHOPE)

Cirrhoses, Liver

Spain, Germany, United Kingdom, Italy, Netherlands, France
Charite University, Berlin, Germany
German Federal Ministry of Education and Research

Unknown

Trial of Simvastatin in Amnestic Mild Cognitive Impairment (MCI) Patients (SIMaMCI)

Mild Cognitive Impairment

Germany
Brasilia Heart Study Group

Completed

Effect of Statin Treatment on Insulin Sensitivity During Myocardial Infarction

Myocardial Infarction

Brazil
Misr University for Science and Technology

Active, not recruiting

Investigate the Effect of Ezetimibe, Simvastatin, and Omega 3- Fatty Acids on Dyslipidemia Patients: a Pharmacokinetics Based Study

Hyperlipidemia; Mixed

Egypt
UCSF Benioff Children's Hospital Oakland
Merck Schering-Plough

Completed

Effects of Ezetimibe on the Absorption of Oxidized Cholesterol

Hypercholesterolemia

United States
Boryung Pharmaceutical Co., Ltd

Recruiting

A Study to Evaluate the Efficacy and Safety of BR1017A and BR1017B Combination Therapy in Essential Hypertension Patients With Primary Hypercholesterolemia

Essential Hypertension | Primary Hypercholesterolemia

Korea, Republic of
Hanmi Pharmaceutical Company Limited

Completed

Investigating the Pharmacokinetic Drug Interactions Between Rosuvastatin and Ezetimibe

Healthy

Korea, Republic of
Organon and Co

Completed

Evaluation of the LDL-C Lowering Effects of Ezetimibe Achieved in Co-administration Therapy With Statins in an Indonesian Population (Study P04276)(COMPLETED)

Hypercholesterolemia
Organon and Co

Completed

Effectiveness and Safety of Ezetimibe Added to Atorvastatin in Patients With High Cholesterol and Coronary Heart Disease (Study P03740)

Hypercholesterolemia | Coronary Heart Disease
Heidelberg University

Completed

Effects on NF-κB Activity: High Dose Simvastatin Versus Combination Therapy With Ezetimibe

Inflammation | Type 2 Diabetes

Germany
Centre hospitalier de l'Université de Montréal...
Centre de Recherche du Centre Hospitalier de l'Université de Montréal

Terminated

Efficacy Study of SIMVASTATIN to Treat Chronic Rhinosinusitis After Failure of Optimal Treatment

Rhinosinusitis

Canada
NVP Healthcare

Completed

to Investigate the Pharmacokinetic Interactions and Safety Between Rosuvastatin and Ezetimibe in Healthy Male Volunteers (NVP-1205)

Healthy
Organon and Co
Merck Sharp & Dohme LLC

Completed

Pediatric Study to Evaluate the Efficacy and Safety of Ezetimibe Monotherapy in Children With Primary Hypercholesterolemia (P05522)

Primary Hypercholesterolemia
Collegium Medicum w Bydgoszczy

Completed

Effectiveness of Treatment of Hypercholesterolemia With Rosuvastatin and Ezetimibe (ROSEZE)

Hypercholesterolemia

Poland
Medical University of Graz

Completed

Fluvastatin 80 mg Ret. vs Combination With Ezetimibe 10 mg in Patients With High Cardiovascular Risk

Hypercholesterolemia

Austria
Akeso
AD Pharmaceuticals Co., Ltd.

Completed

A Study of PCSK9 Inhibitor AK102 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)

Heterozygous Familial Hypercholesterolemia

China
Organon and Co

Completed

TWICE (Ezetimibe Together With Any Statin Cholesterol Enhancement)(0653-060)

Hypercholesterolaemia | Hyperlipidaemia
Organon and Co

Completed

Safety and Tolerability Study of Ezetimibe (SCH 058235/MK-0653) Plus Atorvastatin or Simvastatin in Homozygous Familial Hypercholesterolemia (P01417/MK-0653-019)

Hypercholesterolemia
Organon and Co

Completed

A Study to Determine the Bioequivalence of SCH 900068 Compared to Marketed Products (Protocol No. P07551)

Hyperlipidemia
Chong Kun Dang Pharmaceutical

Completed

CKD-391 Pharmacokinetic Study

Healthy

Korea, Republic of
Yonsei University

Recruiting

Effect of High-intensity Statin With Ezetimibe COmbination theRapy Versus High-intensity sTatin Monotherapy After Percutaneous Coronary Intervention With Drug-eluting Stents; the ESCORT Trial

Coronary Artery Disease Requiring Coronary Revascularization With Newer Generation DES Implantation

Korea, Republic of
University of Illinois at Chicago

Terminated

Use of Simvastatin for the Prevention of Vasospasm in Aneurysmal Subarachnoid Hemorrhage

Aneurysmal Subarachnoid Hemorrhage | Cerebral Vasospasm

United States
University of Leipzig
Institut für Gesundheits- und Praxismanagement GmbH

Withdrawn

Pioglitazone in Impaired Glucose Tolerance

Glucose Metabolism Disorders

Germany
Akeso
AD Pharmaceuticals Co., Ltd.

Completed

A Study of PCSK9 Inhibitor AK102 in Patients With Hypercholesterolemia

Hypercholesterolemia

China
Chong Kun Dang Pharmaceutical

Completed

CKD-391 Pharmacokinetic Study Phase I

Healthy
University of Washington
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Carotid Plaque Characteristics by MRI in AIM-HIGH (Carotid MRI Substudy)

Coronary Artery Disease | Atherosclerosis | Carotid Artery Diseases

United States, Canada
Radboud University Medical Center
Pfizer; Schering-Plough

Completed

Silent Cerebrovascular Lesion and Cognitive Decline Prevention by Cholesterol Lowering in Elderly AF Patients (SPACE)

Inflammation | Atrial Fibrillation | Magnetic Resonance Imaging | Hemostasis | Neuropsychology

Netherlands
St Stephens Aids Trust

Completed

Raltegravir and Ezetimibe PK Study

HIV

United Kingdom
Organon and Co

Completed

A Study of the Efficacy and Safety of MK-0653H in Japanese Participants With Hypercholesterolemia (MK-0653H-832)

Hypercholesterolemia
NVP Healthcare

Completed

Compare the Pharmacokinetics of NVP-1205 and Coadministration of Rosuvastatin and Ezetimibe (NVP-1205)

Dyslipidemia

Korea, Republic of

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