Search clinical trials for: MLN8237 (Alisertib)
Total 77 results
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Millennium Pharmaceuticals, Inc.CompletedOvarian CarcinomaUnited States
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Millennium Pharmaceuticals, Inc.Completed
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M.D. Anderson Cancer CenterMillennium Pharmaceuticals, Inc.CompletedLung Cancer | MesotheliomaUnited States
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Millennium Pharmaceuticals, Inc.CompletedAdvanced Solid Tumors | LymphomasSingapore
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The University of Texas Health Science Center at...No longer availableProstate Cancer
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Millennium Pharmaceuticals, Inc.CompletedSmall Cell Lung Cancer | Non-Small Cell Lung Cancer | Metastatic Breast Cancer | Head and Neck Squamous Cell Carcinoma | Gastroesophageal Adenocarcinoma | Advanced Nonhematological MalignanciesUnited States
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Children's Oncology GroupNational Cancer Institute (NCI)CompletedNeuroblastoma | Unspecified Childhood Solid Tumor, Excluding CNS
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Millennium Pharmaceuticals, Inc.CompletedLymphoma | Advanced Solid TumorsUnited States
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Millennium Pharmaceuticals, Inc.CompletedMultiple Myeloma | Waldenstrom's Macroglobulinemia | Anaplastic Large Cell Lymphoma | Angioimmunoblastic T-cell Lymphoma | Diffuse Large B-cell Lymphoma | B-Cell Chronic Lymphocytic Leukemia | Enteropathy Associated T-cell Lymphoma | B-cell Follicular Lymphoma | B-cell Marginal Zone Lymphoma | B-cell Mantle... and other conditionsUnited States
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Millennium Pharmaceuticals, Inc.CompletedAdvanced MalignanciesUnited States
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Millennium Pharmaceuticals, Inc.CompletedAcute Myelogenous Leukemia | High-Grade Myelodysplastic SyndromeUnited States
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Millennium Pharmaceuticals, Inc.CompletedMantle Cell Lymphoma | Diffuse Large B-cell Lymphoma | Burkitt's Lymphoma | T-cell Lymphoma, Excluding Primary Cutaneous T-cell Lymphoma | Transformed Follicular Lymphoma With ≥ 50% Diffuse Large Cell ComponentUnited States
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Weill Medical College of Cornell UniversityMillennium Pharmaceuticals, Inc.CompletedNeuroendocrine Prostate Cancer | Small Cell Prostate Cancer | Prostate Adenocarcinoma Plus > 50% Immunohistochemical Staining for Neuroendocrine MarkersUnited States
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University of Illinois at ChicagoMillennium Pharmaceuticals, Inc.CompletedMelanoma | Head and Neck Neoplasms | Malignant Neoplasm of Breast | Malignant Neoplasm of Thorax | CNS Malignancy | Malignant Neoplasm of Gastrointestinal Tract | Genitourinary Neoplasms Malignancy and Gender UnspecifiedUnited States
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M.D. Anderson Cancer CenterMillennium Pharmaceuticals, Inc.WithdrawnMalignant Neoplasms of Female Genital Organs | Malignant Neoplasms of Lip Oral Cavity and Pharynx | Malignant Neoplasms of Digestive Organs | Malignant Neoplasms of Male Genital Organs
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Puma Biotechnology, Inc.RecruitingSmall Cell Lung CancerUnited States
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Millennium Pharmaceuticals, Inc.CompletedLymphoma | Advanced Solid TumorsUnited States
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Northwestern UniversityNational Cancer Institute (NCI); Millennium Pharmaceuticals, Inc.; The Leukemia...Active, not recruitingPrimary Myelofibrosis | Myelofibrosis | Acute Megakaryoblastic LeukemiaUnited States
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National Cancer Institute (NCI)CompletedAnaplastic Large Cell Lymphoma | Recurrent Adult Non-Hodgkin Lymphoma | Angioimmunoblastic T-Cell Lymphoma | Hepatosplenic T-Cell Lymphoma | Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma | Recurrent Adult T-Cell Leukemia/Lymphoma | Adult Nasal Type Extranodal NK/T-Cell LymphomaUnited States, Canada
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National Cancer Institute (NCI)NRG OncologyCompletedRecurrent Uterine Corpus Sarcoma | Uterine Corpus LeiomyosarcomaUnited States
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National Cancer Institute (NCI)CompletedStage III Soft Tissue Sarcoma AJCC v7 | Stage IV Soft Tissue Sarcoma AJCC v7 | Recurrent Adult Soft Tissue Sarcoma | Myxofibrosarcoma | Recurrent Leiomyosarcoma | Recurrent Malignant Peripheral Nerve Sheath Tumor | Recurrent Undifferentiated Pleomorphic Sarcoma | Recurrent LiposarcomaUnited States
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Millennium Pharmaceuticals, Inc.Completed
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Millennium Pharmaceuticals, Inc.CompletedAdvanced Solid Tumors | Relapsed/Refractory LymphomaUnited States
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Children's Oncology GroupNational Cancer Institute (NCI)CompletedRecurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Myeloid Leukemia | Recurrent Neuroblastoma | Recurrent Osteosarcoma | Hepatoblastoma | Recurrent Childhood Rhabdomyosarcoma | Recurrent Childhood Kidney Neoplasm | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Childhood... and other conditionsUnited States, Canada
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Sidney Kimmel Cancer Center at Thomas Jefferson...Millennium Pharmaceuticals, Inc.CompletedAdult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Oligodendroglioma | Adult Pilocytic Astrocytoma | Adult Pineal Gland Astrocytoma | Recurrent... and other conditionsUnited States
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University of Colorado, DenverCompletedMetastatic Breast Cancer | Solid TumorsUnited States
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Puma Biotechnology, Inc.Not yet recruitingMetastatic Breast Cancer | Recurrent Breast Cancer | Hormone Receptor Positive HER-2 Negative Breast CancerUnited States
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Eric Bernicker, MDMillennium Pharmaceuticals, Inc.; The Methodist Hospital Research InstituteWithdrawnCD30-positive Lymphoma | CD30-positive Solid TumorUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingMalignant Solid Neoplasm | Head and Neck Squamous Cell CarcinomaUnited States
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University of California, DavisNational Cancer Institute (NCI); Millennium Pharmaceuticals, Inc.CompletedUnspecified Adult Solid Tumor, Protocol Specific | Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IIIA Colon Cancer | Recurrent Colon Cancer | Recurrent Rectal CancerUnited States
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Fox Chase Cancer CenterMillennium Pharmaceuticals, Inc.TerminatedNon-small Cell Lung Cancer Metastatic | Non-small Cell Lung Cancer RecurrentUnited States
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Millennium Pharmaceuticals, Inc.CompletedAdvanced Solid Tumors | Adenocarcinoma of the ProstateUnited States
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Millennium Pharmaceuticals, Inc.CompletedFallopian Tube Cancer | Breast Carcinoma | Ovarian Carcinoma | Peritoneal CancerUnited States
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Fondazione IRCCS Istituto Nazionale dei Tumori,...CompletedTransitional Cell Carcinoma | Bladder CancerItaly
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National Cancer Institute (NCI)CompletedRecurrent Adult Burkitt Lymphoma | Recurrent Adult Lymphoblastic Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone Lymphoma | Waldenstrom... and other conditionsUnited States
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Collin BlakelyPuma Biotechnology, Inc.Active, not recruitingLung Cancer Metastatic | EGFR Gene MutationUnited States
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Millennium Pharmaceuticals, Inc.CompletedSmall Cell Lung CancerUnited States, France, Germany, Spain, Belgium, Poland, Canada, Hungary, Italy, Czechia
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M.D. Anderson Cancer CenterCompletedStage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Recurrent Lung Non-Small Cell CarcinomaUnited States
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US Oncology ResearchMillennium Pharmaceuticals, Inc.Active, not recruitingBreast Cancer | Breast Tumors | Breast Carcinoma | Malignant Neoplasm of BreastUnited States
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Edward KimNational Cancer Institute (NCI); TakedaCompletedUnspecified Adult Solid Tumor, Protocol Specific | Acinar Cell Adenocarcinoma of the Pancreas | Duct Cell Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic CancerUnited States
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Ohio State University Comprehensive Cancer CenterMillennium Pharmaceuticals, Inc.TerminatedExtranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade... and other conditionsUnited States
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Mayo ClinicNational Cancer Institute (NCI)CompletedStage IV Breast Cancer | Recurrent Breast Carcinoma | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer | Estrogen Receptor Positive | Progesterone Receptor PositiveUnited States
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Millennium Pharmaceuticals, Inc.TerminatedAdvanced and Metastatic Gastric or Gastroesophageal AdenocarcinomaUnited States, Spain
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Mayo ClinicNational Cancer Institute (NCI)Active, not recruitingStage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Invasive Breast Carcinoma | Stage IIIC Breast Cancer | HER2/Neu Negative | Stage III Breast Cancer | Postmenopausal | Estrogen Receptor StatusUnited States
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Millennium Pharmaceuticals, Inc.WithdrawnAdvanced Nonhematologic MalignanciesUnited States
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Millennium Pharmaceuticals, Inc.CompletedTransformed Follicular Lymphoma | Diffuse Large B-Cell Lymphoma | Mantle Cell Lymphoma | Burkitt's LymphomaUnited States, Spain, Italy, United Kingdom
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Massachusetts General HospitalCompleted
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National Cancer Institute (NCI)CompletedAlisertib and Romidepsin in Treating Patients With Relapsed or Refractory B-Cell or T-Cell LymphomasRecurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Recurrent Mantle Cell Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma With... and other conditionsUnited States
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Mayo ClinicCompletedRefractory Multiple MyelomaUnited States
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Appalachian State UniversityNorth Carolina Agriculture & Technical State UniversityCompletedPostmenopausal Osteoporosis | Osteoporosis, OsteopeniaUnited States