Search clinical trials for: Matching placebo to K-757 and K-833 BID

Total 229 results

Kallyope Inc.

Active, not recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of K-757 and K-833 in Overweight/Obese Patients With Type 2 Diabetes

Obesity | Type 2 Diabetes Mellitus (T2DM)

United States
Kallyope Inc.

Completed

A Study to Evaluate the Safety, Tolerability, and Weight Loss Efficacy of K-757 Alone and in Combination With K-833

Obesity

United States
Kallyope Inc.

Completed

A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of K-757 and K-833 in Overweight/Obese Patients With Type 2 Diabetes

Obesity | Type 2 Diabetes Mellitus in Obese

United States
Kallyope Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of K-757 in Healthy Overweight/Obese Volunteers

Obesity

United States
Kowa Company, Ltd.

Completed

A Study to Evaluate the Safety of K-755 in Healthy Volunteers

Healthy

Australia
Boryung Pharmaceutical Co., Ltd

Completed

Efficacy, Safety and Pharmacodynamic/Pharmacokinetic Study of Fimasartan (BR-A-657•K) (Fimasartan)

Essential Hypertension
Bio-K Plus International Inc.
ethica Clinical Research Inc.

Completed

Efficacy of BIO-K+ CL1285® Prophylaxis in the Prevention of Traveler's Diarrhea in Adults

Diarrhea

Canada
Bio-K Plus International Inc.
Centre Hospitalier Pierre-Le Gardeur

Withdrawn

Evaluation of the Efficacy of Bio-K+ Cl-1285® In the Nasal Decolonization of Methicillin Resistant Staphylococcus Aureus (MRSA) Carrier Patients (MRSA)

MRSA Colonization

Canada
Bio-K Plus International Inc.
Centre hospitalier de l'Université de Montréal (CHUM)

Terminated

Study of Bio-K+® in the Reduction of the Risk of Clostridium Difficile Infection and Antibiotic Associated Diarrhea

Clostridium Difficile Infection | Antibiotic Associated Diarrhea

Canada
Kowa Company, Ltd.

Completed

K-924 Phase III Confirmatory Study

Hypercholesterolemia

Japan
RenJi Hospital

Unknown

The Efficacy and Safety of K-001 in the Treatment of Advanced Pancreatic Cancer

Pancreatic Cancer

China
Optimal Acuity Corporation

Not yet recruiting

Vision Improvement for Legally Blind Dry AMD Patients

Dry Age-related Macular Degeneration | Vision Impairment and Blindness
McMaster University

Unknown

Comparison of Two Formulations of Bio-K

Antibiotic-Associated Diarrhea

Canada
Kowa Company, Ltd.

Recruiting

A Phase 3 Study to Evaluate the Efficacy and Safety of K-877 in Chinese Patients With High TG and Low HDL-C

Hyperlipidemia

China
Aldeyra Therapeutics, Inc.

Completed

The RENEW Trial: A Multi-Center, Randomized, Double-Masked, Parallel-Group, Vehicle-Controlled, Adaptive Phase 3 Clinical Trial to Assess the Safety and Efficacy of Subjects With Dry Eye Disease

Dry Eye

United States
Kowa Research Institute, Inc.

Recruiting

Study to Evaluate the Efficacy and Safety of K-808 (Pemafibrate) in Participants With Primary Biliary Cholangitis (PBC) With Inadequate Response to Ursodeoxycholic Acid (UDCA) and/or Obeticholic Acid (OCA) Treatment.

Primary Biliary Cholangitis

United States, Japan
Optimal Acuity Corporation
Bochner Eye Institute

Not yet recruiting

Vision Improvement for Patients With Age-Related Macular Degeneration (AMD)

Age-related Macular Degeneration

Canada
Bio-K Plus International Inc.
Sprim Advanced Life Sciences

Completed

Efficacy and Safety Study in the Prevention of Antibiotic-Associated Diarrhea (AAD) and Clostridium Difficile-Associated Diarrhea (CDAD) in Hospitalized Adult Patients Exposed to Nosocomial Infection

Clostridium Difficile-Associated Diarrhea | Antibiotic-Associated Diarrhea
Kowa Research Institute, Inc.

Completed

A Study to Confirm the Efficacy and Safety of K-161 Ophthalmic Solution for Treatment of Moderate to Severe Dry Eye Disease

Dry Eye Disease

United States
Kowa Company, Ltd.

Completed

A Study of Pemafibrate in Patients With Nonalcoholic Fatty Liver Disease (NAFLD)

Non-Alcoholic Fatty Liver Disease

Japan
Urovant Sciences GmbH
Dasman Diabetes Institute; Ion Channel Innovations

Completed

Phase 2A Clinical Trial Evaluating the Potential Activity and Safety of hMaxi-K Gene for ED

Erectile Dysfunction

Kuwait
Bio-K Plus International Inc.
Sprim Advanced Life Sciences

Suspended

BIO-K+ CL1285 for Prevention of Recurrent Clostridium Difficile Infection

Recurrent Clostridium Difficile Infection

United States
Kowa Research Institute, Inc.

Completed

Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Mild or Moderate Renal Impairment

Severe Hypertriglyceridemia

United States, Czechia, Belarus, Hungary, Russian Federation, Poland, Bulgaria, Georgia, Ukraine
Kowa Research Institute, Inc.

Completed

A Study to Investigate the Safety and Efficacy of Ripasudil (K-321) Eye Drops After Cataract Surgery

Corneal Edema After Cataract Surgery

United States, Puerto Rico
Kowa Research Institute, Inc.

Completed

Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Normal Renal Function

Severe Hypertriglyceridemia

United States, Hungary, Belarus, Bulgaria, Czechia, Georgia, Poland, Russian Federation, Ukraine
Kowa Research Institute, Inc.

Completed

A Study Assessing the Safety, Efficacy, and Optimum Dosage of K-161 in Subjects With Moderate to Severe Dry Eye Disease

Dry Eye Disease

United States
Kowa Research Institute, Inc.

Recruiting

A Study to Investigate the Safety and Efficacy of K-321 Eye Drops After Simultaneous Cataract Surgery and Descemetorhexis in Participants With Fuchs Endothelial Corneal Dystrophy (FECD)

Fuchs Endothelial Corneal Dystrophy

United States, United Kingdom, Spain, Germany, Canada, Denmark
Kowa Research Institute, Inc.

Recruiting

A Study to Evaluate the Safety and Efficacy of K-321 Eye Drops After Descemetorhexis in Participants With Fuchs Endothelial Corneal Dystrophy (FECD)

Fuchs Endothelial Corneal Dystrophy

United States, Germany, Spain, Canada, United Kingdom, Denmark
University of Pavia
Foundation IRCCS San Matteo Hospital

Recruiting

Effect of the Association of Berberine Fitosoma® and Monacolin K MonaKoPure® on Glyco-metabolic Parameters in Dysglycemic and Dyslipidemic Patients.

Dyslipidemias | Dysglycemia

Italy
Bispebjerg Hospital

Recruiting

The InterVitaminK Trial - Effects of Vitamin K Supplementation on Cardiovascular, Metabolic, and Bone Health (InterVitaminK)

Coronary Artery Calcification | Arterial Stiffness

Denmark
Kowa Research Institute, Inc.

Completed

Study to Investigate the Safety and Efficacy of K-321 in Patients With Fuchs Endothelial Corneal Dystrophy (FECD) Following Descemetorhexis

Fuchs' Endothelial Corneal Dystrophy

United States, Australia, Germany, Spain, Denmark
Instituto Mexicano del Seguro Social
Rodolfo Guardado Mendoza; Marco Antonio Ocampo Apolonio; Texar Alfonso Pereyra...

Completed

Effects of Fhytomenadione on Coronary Artery Calcification of Hemodialysis Patients

Coronary Calcification

Mexico
Maastricht University Medical Center

Completed

Comparison of Efficacy of Different Dosages Vitamin K2

Carboxylation Level | Vitamin K-dependent Proteins

Netherlands
Ain Shams University

Completed

Comparative Study Evaluating the Effect of Vitamin K1 Versus Vitamin K2 on Vascular Calcification in Dialysis Patients

End Stage Renal Disease on Dialysis

Egypt
Maastricht University Medical Center

Completed

Biocomparison Study

Bone Health | Vascular Health

Netherlands
Bio-K Plus International Inc.
Sprim Advanced Life Sciences

Completed

Effect of BIO-K+ on Symptoms of Irritable Bowel Syndrome

Irritable Bowel Syndrome

United States
Catholic University of Salta

Completed

Vitamin K2 Supplementation and Vascular Calcification

Renal Disease
Tufts University
University of North Carolina, Chapel Hill; Tufts Medical Center

Recruiting

Effects of Vitamin K on Lower-extremity Function in Adults With Osteoarthritis:

Osteo Arthritis Knee

United States
National and Kapodistrian University of Athens

Recruiting

SLOW-Slower Progress of caLcificatiOn With Vitamin K2

Aortic Valve Stenosis | Mitral Valve Stenosis | Aortic Valve Calcification | Mitral Annular Calcification | Mitral Valve Calcification

Greece
Dasman Diabetes Institute
Kappa Bioscience

Recruiting

Vitamin K2 and Muscle Weakness in Type 2 Diabetes (SARK2)

Diabete Type 2

Kuwait
Biogen

Completed

Effects of Vitamin K on Redness Associated With Injection Site Reactions in Participants Treated With Plegridy (VITALITY)

Relapsing-Remitting Multiple Sclerosis

Italy
Kowa Company, Ltd.

Recruiting

A Phase III Confirmatory Study of K-877 (Pemafibrate) in Patients With Hypercholesterolemia and Statin Intolerance

Hypercholesterolemia

Japan
Duke University

Completed

The Effects of Potassium on Glucose Metabolism in African Americans

Borderline Hypokalemia

United States
Guy's and St Thomas' NHS Foundation Trust

Unknown

Vitamin K as Additive Treatment in Osteoporosis (VITKANDOP)

Post-menopausal Osteoporosis

United Kingdom
UMC Utrecht

Completed

A Randomized, Placebo-controlled, Double Blind Trial to Investigate Whether Vitamin K2 Can Influence Arterial Calcification in Patients With Type 2 Diabetes (Vitacal)

Diabetes Mellitus Type 2 | Arterial Calcification

Netherlands
Zealand University Hospital

Completed

Effect of Vitamin K2 (MK7) on Cardiovascular and Bone Disease in Dialysis Patients (RenaKvit)

Cardiovascular Disease | Bone Disease | Endstage Renal Disease | Vitamin K Supplementation

Denmark
Maastricht University Medical Center

Unknown

Bicuspid Aortic Valve Stenosis and the Effect of vItamin K2 on Calciummetabolism on 18F-NaF PET/MRI (BASIK2)

Aortic Valve Stenosis | Bicuspid Aortic Valve

Netherlands
Maastricht University Medical Center

Completed

Beneficial Effects of Long Term Menaquinone-7

Arteriosclerosis | Bone Loss

Netherlands
Ottawa Hospital Research Institute

Completed

Low Dose Supplementation to Improve Anticoagulation Control With Oral Vitamin K as an Adjuvant to Warfarin Therapy (LOCK)

Coagulation

Canada
St. Joseph's Healthcare Hamilton
McMaster University; University of Western Ontario, Canada

Completed

Does Low Dose Oral Vitamin K Improve International Normalized Ratio (INR) Stability? (OVWAC VII)

Thrombosis | Bleeding | Coagulation

Canada

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