Search clinical trials for: Mepolizumab (a-IL-5 antibody)

Total 696 results

University Hospital Inselspital, Berne

Completed

Anti-IL-5 Therapy in Bullous Pemphigoid (BP)

Pemphigoid, Bullous

Switzerland
Brigham and Women's Hospital
GlaxoSmithKline

Completed

Mepolizumab As a Steroid-sparing Treatment Option in the Churg Strauss Syndrome (MATOCSS)

Churg Strauss Syndrome

United States
National Institute of Allergy and Infectious Diseases...
GlaxoSmithKline; Rho Federal Systems Division, Inc.; Inner-City Asthma Consortium

Completed

A Trial of Mepolizumab Adjunctive Therapy for the Prevention of Asthma Exacerbations in Urban Children (MUPPITS-2)

Asthma

United States
University of Wisconsin, Madison

Completed

Eosinophilic Airway Inflammation and Mepolizumab

Asthma

United States
Shanghai Huaota Biopharmaceutical Co., Ltd.

Completed

HB0034 in Patients With Generalized Pustular Psoriasis (GPP)

Generalized Pustular Psoriasis

China
Millennium Pharmaceuticals, Inc.

Completed

Phase 2 Study of the Safety and Efficacy of LDP-02 in Mildly to Moderately Active Crohn's Patients

Crohn's Disease
Genentech, Inc.

Completed

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of UTTR1147A Compared With Placebo and With Vedolizumab in Participants With Moderate to Severe Ulcerative Colitis (UC)

Ulcerative Colitis

Italy, Spain, Serbia, Poland, Russian Federation, United States, Ukraine, Bulgaria, Georgia, Germany, Greece, Hungary, Ireland, Israel, Moldova, Republic of, United Kingdom
Keymed Biosciences Co.Ltd

Recruiting

The Study of CM310 in Patients With Atopic Dermatitis

Moderate-to-severe Atopic Dermatitis

China
Sinocelltech Ltd.

Not yet recruiting

Evaluate the Safety and Tolerability of SCT650C in Healthy Volunteers

Autoimmune Disease

Australia
Sinocelltech Ltd.

Not yet recruiting

Efficacy and Safety of SCT650C in Participants With Axial Spondyloarthritis

Axial Spondyloarthritis

Turkey
Takeda

Not yet recruiting

A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease

Crohn's Disease | Ulcerative Colitis
Takeda

Recruiting

A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)

Crohn's Disease (CD)

United States, Australia, Israel, Belgium, Hungary, Canada, China, Croatia, Czechia, Greece, Italy, Japan, Korea, Republic of, Poland, United Kingdom, Lithuania, Slovakia, Spain
National Cancer Institute (NCI)

Completed

Continuous Infusion of rhIL-15 for Adults With Advanced Cancer

Lymphoma | Carcinoma

United States
Beijing VDJBio Co., LTD.

Completed

Clinical Study of Single Dose IL-6R mAb Injection in RA Patients

Rheumatoid Arthritis

China
University Hospital, Brest

Completed

Lymphocyte and Cytokine Disturbances in Polymyalgia Rheumatica (TENOR-IMMUNO)

Polymyalgia Rheumatica

France
McMaster University
St. Joseph's Healthcare Hamilton; Teva Pharmaceuticals USA

Completed

Anti-Interleukin-5 (IL5) Monoclonal Antibody (MAb) in Prednisone-dependent Eosinophilic Asthma

Severe Persistent Asthma | Eosinophilic Bronchitis

Canada
Galderma R&D

Completed

Safety and Efficacy of Nemolizumab in PN

Prurigo Nodularis

Germany, Poland, France, Austria
Shanghai Huaota Biopharmaceutical Co., Ltd.

Recruiting

Efficacy and Safety of HB0034 in Patients With Generalized Pustular Psoriasis (GPP)

Generalized Pustular Psoriasis (GPP)

China
Medical University of Vienna
Charite University, Berlin, Germany; University of Alberta; CSL Behring

Completed

A Pilot Trial of Clazakizumab in Late ABMR

Antibody-mediated Rejection

Austria, Germany
Dow University of Health Sciences
University of Karachi

Completed

Evaluation of Root Roughness and Smear Layer Formation Using Conventional and Contemporary Dental Curettes

Dental Calculus

Pakistan
Shanghai Junshi Bioscience Co., Ltd.
Sponsor GmbH

Recruiting

Evaluate the Preliminary Efficacy, Safety, and PK of Subcutaneous JS005 in Chinese Adult Patients With Active AS

Active Ankylosing Spondylitis

China
Shanghai Junshi Bioscience Co., Ltd.
Sponsor GmbH

Recruiting

Evaluate the Preliminary Efficacy, Safety, and PK of Subcutaneous JS005 in Chinese Adult Patients With Active Nr-axSpA

Non-radiographic Axial Spondyloarthritis

China
Genrix (Shanghai) Biopharmaceutical Co., Ltd.

Completed

to Evaluate the Preliminary Efficacy and Safety of GR1501 Injection in Patients With Active Axial Spondyloarthritis

Axial Spondyloarthritis

China
Kanuni Sultan Suleyman Training and Research Hospital

Completed

GDM Patients and Serum Amyloid A and Interleukin-1 (IL-1) Receptor Antagonist

Gestational Diabetes

Turkey
Centre Hospitalier Universitaire de Besancon

Recruiting

Biomedicines and Bacterial Translocation in Spondyloarthritis (TEARE-BIO)

Axial Spondyloarthritis

France
Reza Dana, MD

Completed

Topical IL-1-Ra for Treatment of Posterior Blepharitis

Posterior Blepharitis
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0354, Anti-IL-6 Chimeric Monoclonal Antibody in Patients With Metastatic Prostate Cancer That Did Not Respond to Hormone Therapy

Prostate Cancer

United States
Bio-Thera Solutions

Active, not recruiting

Assessment on Efficacy and Safety of BAT2306 and Cosentyx® in Plaque Psoriasis Patients

Plaque Psoriasis

China
Jagiellonian University

Recruiting

Activity of Chronic Inflammation in PCOS

Polycystic Ovary Syndrome

Poland
Shanghai Zhongshan Hospital

Recruiting

A Pilot Study in Severe Patients With Takayasu Arteritis.

Takayasu Arteritis | Treatment | Tocilizumab | Adalimumab

China
Margaret Ragni
Wyeth is now a wholly owned subsidiary of Pfizer; University of North Carolina

Terminated

IL-11 in Adults With Von Willebrand Disease Undergoing Surgery

Von Willebrand Disease

United States
Eli Lilly and Company

Completed

A Biomarker Study of Solanezumab in Patients With and Without Alzheimer's

Alzheimer's Disease

United States
Facet Biotech

Completed

Pilot Study in Patients With Symptomatic Steroid-Naive Asthma

Asthma

United States
Ahvaz Jundishapur University of Medical Sciences

Completed

Effect of Self Management Program on Clinical Status of COPD Patients

COPD
Eli Lilly and Company

Terminated

Progress of Mild Alzheimer's Disease in Participants on Solanezumab Versus Placebo (EXPEDITION 3)

Alzheimer's Disease

United States, Italy, France, Japan, Australia, Germany, Spain, Sweden, Canada, Poland, United Kingdom
Centre Jean Perrin

Completed

Assessment of 99mTc-NTP 15-5 Uptake on Cartilage, a New Proteoglycan Tracer (CARSPECT)

Breast Cancer | Osteoarthritis, Knee

France
National Cancer Institute (NCI)

Completed

Apolizumab in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Recurrent Small Lymphocytic Lymphoma | Refractory Chronic Lymphocytic Leukemia | Stage III Small Lymphocytic Lymphoma | Stage IV Small Lymphocytic Lymphoma | Noncontiguous Stage II Small Lymphocytic Lymphoma

United States
National Cancer Institute (NCI)

Completed

Monoclonal Antibody Therapy in Treating Patients With Chronic Lymphocytic Leukemia, Lymphocytic Lymphoma, Acute Lymphoblastic Leukemia, or Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone Lymphoma | Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent Small Lymphocytic... and other conditions

United States
Oregon Research Institute
National Institute on Drug Abuse (NIDA)

Completed

Tobacco Quitlines:Adjunct to Dental Office Tobacco Intervention

Tobacco Use Cessation

United States
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

A Clinical Study to Evaluate the Efficacy and Safety of Subcutaneous JS005 Injection in the Treatment of Adults With Moderate to Severe Chronic Plaque Psoriasis

Moderate to Severe Chronic Plaque Psoriasis

China
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Recruiting

A Phase Ib/II Study of Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection in Chinese Participants With Acute Gout

Acute Gout

China
Alimentiv Inc.
Takeda Development Center Americas, Inc.

Active, not recruiting

Determination of the Optimal Treatment Target in Ulcerative Colitis (VERDICT)

Colitis, Ulcerative

Canada, Italy, United Kingdom, Poland, Netherlands, Ukraine, Belarus, United States, Belgium, France
Biocad

Completed

First-in-human Study to Evaluate Safety, Tolerability and Pharmacokinetics of Various Doses of BCD-085 in Healthy Subjects

Healthy
The First Affiliated Hospital of Soochow University
The First Affiliated Hospital with Nanjing Medical University; The Affiliated... and other collaborators

Recruiting

Vedolizumab, Anti-CD25 Antibody, Rapid Reduction of Glucocorticoids for SR-aGVHD With Gastrointestinal Involvement

Safety and Efficacy

China
Universidad de Granada
Hospital Clinico Universitario San Cecilio; Centro de Investigación Biomédica; Instituto Mixto Universitario Deporte y Salud and other collaborators

Completed

Effects of an Exercise Program on Cognition and Brain in Overweight/Obese Preadolescent Children (ActiveBrains)

Obesity | Overweight | Mental Health Wellness 1 | Cognitive Function 1, Social
Biocad

Completed

First-in-human Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Various Doses of BCD-121 in Healthy Subjects

Healthy
Shanghai Junshi Bioscience Co., Ltd.
Sponsor GmbH

Recruiting

A Clinical Study of JS005 in Patients With Ankylosing Spondylitis

Ankylosing Spondylitis

China
University of Chicago

Completed

Study of MAGE-3/Melan-A/gp 100/NA17 and rhIL-12 With/Out Low Dose IL-2 in Metastatic Melanoma

Metastatic Melanoma

United States
Shanghai Junshi Bioscience Co., Ltd.

Unknown

Phase I Study of Comparing Single Dose JS005 (Recombinant Humanized Monoclonal Antibody Against IL-17A) With Placebo in Tolerability, Safety, Immunogenicity and Pharmacokinetic in Healthy Volunteers

Tolerability, Safety, Immunogenicity and Pharmacokinetic of JS005

China
AbbVie (prior sponsor, Abbott)

Completed

Efficacy and Safety of ABT-874 in Subjects With Moderate to Severe Chronic Plaque Psoriasis

Psoriasis

United States, Canada

Search clinical trials for: Mepolizumab (a-IL-5 antibody)

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