Search clinical trials for: Metformin placebo

Total 55544 results

University of Florida
ALS Association

Active, not recruiting

Safety and Therapeutic Potential of the FDA-approved Drug Metformin for C9orf72 ALS/FTD

Frontotemporal Dementia | C9orf72 Amyotrophic Lateral Sclerosis (ALS)

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Stereotactic Radiosurgery and Metformin in Patients With Borderline-Resectable or Locally-Advanced Pancreatic Cancer

Acinar Cell Adenocarcinoma of the Pancreas | Duct Cell Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage I-III Pancreatic Cancer

United States
Tianjin Medical University Cancer Institute and...
Innovent Biologics (Suzhou) Co. Ltd.

Unknown

Sintilimab Combined With Metformin in First-Line Chemotherapy Refractory Advanced NSCLC Patients (SMART)

Non Small Cell Lung Cancer

China
Peking University

Unknown

Metformin in Combined With Cisplatin Plus Paclitaxel With Advanced Esophageal Squamous Cell Carcinoma (ECMTPneo) (ECMTPneo)

Esophageal Squamous Cell Carcinoma

China
Poznan University of Medical Sciences
University of California, San Diego

Unknown

Androgen Responses to hCG and Ovarian Morphology in PCOS

PCOS

Poland
Novo Nordisk A/S

Completed

Comparison of Repaglinide and Metformin Administered Alone or in Combination in Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

China
Novo Nordisk A/S

Completed

Comparison of Metformin, Repaglinide or the Combination of Both in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Spain
HaEmek Medical Center, Israel

Completed

A Comparison Between Two Oral Hypoglycemics - Metformin and Glybenclamide for the Treatment of Gestational Diabetes Mellitus

Gestational Diabetes Mellitus

Israel
M.D. Anderson Cancer Center

Terminated

An Open-Labeled Pilot Study of Biomarker Response Following Short-Term Exposure to Metformin

Colorectal Carcinoma

United States
Eunice Kennedy Shriver National Institute of Child...
University of Pittsburgh; University of Washington; University of Texas; RTI International and other collaborators

Unknown

Glyburide and Metformin for Gestational Diabetes Mellitus (GDM) (GDM)

Gestational Diabetes Mellitus

United States
IlDong Pharmaceutical Co Ltd

Completed

A Open-label, Single-dose, 2-Sequence, 2-Period, Crossover Study to Assess Safety and Pharmacokinetics of a Nateglinide/Metformin HCl Combined Tablet Compared With a Nateglinide 120 mg Tablet and Metformin HCl 500 mg Tablet Under Fasting Conditions in Healthy Male Subjects

Healthy Volunteers

Korea, Republic of
GlaxoSmithKline

Completed

Drug Interactions From Simultaneous Administration Of Metformin And GSK189075 To Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Type 2 Diabetes Mellitus

Mexico
LG Life Sciences

Completed

Pharmacokinetic/Pharmacodynamic Drug-drug Interaction of LC15-0444 and Metformin After Oral Administration in Healthy Male Subjects

Healthy

Korea, Republic of
Second Affiliated Hospital, School of Medicine,...

Recruiting

Retrospective Analysis for Patients With Metabolic Syndrome

Metabolic Syndrome

China
University of Alabama at Birmingham
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Preventing Diabetes in the Deep South: Extending Partnerships and Adapting Interventions to Reach Rural Communities at High Risk.

Pre-diabetes

United States
King Edward Medical University

Completed

Comparison of the Effects of Metformin and Pioglitazone on Liver Enzymes and Ultrasound Changes in Non-Diabetic Non-Alcoholic Fatty Liver

NAFLD

Pakistan
Beth Israel Medical Center
St. Luke's-Roosevelt Hospital Center

Terminated

Metformin and Carbohydrate Restriction With Platinum Based Chemotherapy In Stage IIIB/IV Non-Squamous Non-Small Cell Lung Cancer (NS-NSCLC) (METRO)

Nonsquamous Nonsmall Cell Neoplasm of Lung | Non-small Cell Lung Cancer Metastatic | Non-small Cell Lung Cancer Stage IIIB/IV

United States
GlaxoSmithKline

Completed

Efficacy and Safety Study of Rosiglitazone/Metformin Therapy vs Rosiglitazone and Metformin in Type 2 Diabetes Subjects

Diabetes Mellitus, Type 2

United States, Canada, Korea, Republic of, Australia, New Zealand, Mexico, Brazil
GlaxoSmithKline

Completed

Diabetes Study With Rosiglitazone Monotherapy Versus Metformin Or Glyburide/Glibenclamide

Diabetes Mellitus, Type 2

United States, Germany, Canada, Belgium, Denmark, Spain, Ireland, Netherlands, United Kingdom, Hungary, Italy, France, Austria, Czechia, Norway, Finland, Sweden
Novo Nordisk A/S

Completed

Efficacy and Safety of Repaglinide and Metformin Combined in Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Malaysia, Thailand, China, Philippines
Caio Eduardo Gonçalves Reis
University of Brasilia; Conselho Nacional de Desenvolvimento Científico e Tecnológico and other collaborators

Completed

Metabolic Effects of a Caloric Restriction High/Low Glycemic Index Diet Plus Metformin in Overweight/Obese Subjects

Obesity

Brazil
Shengjing Hospital

Completed

CANA/Met in Non-diabetic Women With PCOS

Polycystic Ovary Syndrome

China
Brigham and Women's Hospital
Arthritis Foundation

Recruiting

Preventing Injured Knees From osteoArthritis: Severity Outcomes (PIKASO)

Osteoarthritis, Knee | Post-traumatic Osteoarthritis | ACL Tear

United States
Cairo University
German University in Cairo

Recruiting

Drug Repurposing for the Prevention of Chemotherapy-induced Peripheral Neuropathy (CIPN)

Chemotherapy-induced Peripheral Neuropathy

Egypt
AHS Cancer Control Alberta

Terminated

Prevention of Metabolic Syndrome and Increased Weight Using Metformin Concurrent to Androgen Deprivation Therapy and Radiotherapy for Locally Advanced Adenocarcinoma of the Prostate (PREMIUM)

Prostatic Neoplasm

Canada
Hospital de Clinicas de Porto Alegre

Unknown

The Hypotensive Effect of Metformin in Hypertensive Patients.

Hypertension

Brazil
Sadat City University

Recruiting

The AMPK Modulator Metformin as a Novel Adjunct to Conventional Therapy in Patients With Knee Osteoarthritis

Osteo Arthritis Knee

Egypt
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Terminated

Medical Optimization of Management of Type 2 Diabetes Complicating Pregnancy (MOMPOD) (MOMPOD)

Diabetes | Pregnancy

United States
Children's Hospital Medical Center, Cincinnati
University of Cincinnati

Completed

Metformin to Augment Low Milk Supply (MALMS) Study (MALMS)

Insulin Resistance | Pre-diabetes | Low Milk Supply | Suppressed Lactation

United States
AstraZeneca

Completed

Saxagliptin Treatment in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise

Diabetes Mellitus, Type 2

United States, Canada, Mexico, Puerto Rico, Taiwan, Australia
Gilead Sciences

Completed

A Phase 3 Study of Ranolazine in Subjects With Type 2 Diabetes Who Are Inadequately Controlled on Metformin Alone

Type 2 Diabetes Mellitus

United States, Russian Federation, Israel, South Africa, India, Hungary, Ukraine, Canada, Czech Republic, Mexico, Poland
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety of Sitagliptin/Metformin Fixed-Dose Combination (FDC) Compared to Glimepiride in Participants With Type 2 Diabetes Mellitus (MK-0431A-202)

Type 2 Diabetes Mellitus
Novo Nordisk A/S

Completed

To Compare the Effect of Liraglutide When Given Together With Metformin With the Effect of Metformin Given Alone and With the Effect of Glimepiride and Metformin Given Together (LEAD-2)

Diabetes Mellitus, Type 2 | Diabetes

Slovakia, India, Italy, Russian Federation, Spain, Denmark, United Kingdom, Sweden, Belgium, Ireland, Argentina, Hungary, Norway, South Africa, Germany, Croatia, Netherlands, Bulgaria, Australia, Romania
LG Chem

Completed

BE Study of the Combinations of Gemigliptin/Metformin HCl Extended Release 50/1000mg(25/500mg x 2 Tablets) in Comparison to Each Component Administered Alone

Healthy Male Volunteers

Korea, Republic of
Boehringer Ingelheim
Eli Lilly and Company

Completed

Relative Bioavailability of 2 Fixed Dose Combinations of Empagliflozin/Metformin Extended Release (XR) Compared With Single Tablets

Healthy

United States
University of Southern Denmark

Completed

Inter- and Intra-individual Variations in Metformin Pharmacokinetics - The Importance of Genes and Drug Interactions

Metformin | Organic Cation Transporter 1 | Codeine

Denmark
National Institute of Diabetes and Digestive and...

Completed

Prebiotics and Metformin Improve Gut and Hormones in Type 2 Diabetes in Youth (MIGHTY-fiber)

Diabetes

United States
Merck Sharp & Dohme LLC

Completed

MK0431 (Sitagliptin) and Metformin Co-Administration Factorial Study in Patients With Type 2 Diabetes Mellitus (0431-036)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC

Completed

A Study to Assess the Safety and Efficacy of Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (T2DM) and Inadequate Glycemic Control (MK-3102-011)

Type 2 Diabetes Mellitus
University of Stellenbosch
University of Rochester; Fogarty International Center of the National Institute...

Recruiting

A Pilot Study of Metformin to Reduce Cerebrovascular Dysfunction in Participants With HIV and Metabolic Syndrome. (SMART)

Metabolic Syndrome | HIV Seropositivity

South Africa
Merck KGaA, Darmstadt, Germany

Completed

Bioequivalence and Drug - Drug Interaction Study of Metformin/Gliclazide in Healthy Participants

Healthy

Germany
Sanofi

Completed

A Phase I Study to Assess the Pharmacokinetics of Metformin When Administered Alone and in Combination With Vandetanib (Vandetanib)

Healthy

United States
Xiang Guang-da

Completed

Pioglitazone Regress Left Ventricular Mass in Type 2 Diabetes With Ischeamia Heart Disease

Endothelial Function | LVM | Type 2 Diabetic Patients With IHD

China
National Institute of Allergy and Infectious Diseases...

Completed

Metformin and Rosiglitazone, Alone or in Combination, in HIV-Infected Patients With Insulin and Fat Abnormalities

HIV Infections | Hyperinsulinemia | Lipodystrophy

United States
University of New Mexico

Completed

Metformin Compared to Glyburide in Gestational Diabetes

Gestational Diabetes

United States
Anji Pharma

Completed

A Phase 1 Study of ANJ900 Chinese Healthy Subjects

Healthy

China
Cairo University

Completed

Effect of Aerobic Exercise on Polycystic Ovary Syndrome

Polycystic Ovary Syndrome

Egypt
Khyber Medical University Peshawar

Completed

Treatment With Metformin and Combination of Metformin and Pioglitazone in Polycystic Ovarian Syndrome

Polycystic Ovarian Syndrome

Pakistan
Merck KGaA, Darmstadt, Germany

Completed

Glucophage Extended Release (GXR) China Bioequivalence Study (Nantong - Darmstadt)

Healthy

China
Taipei Medical University WanFang Hospital

Terminated

The Combination Effect of Statin Plus Metformin on Relapse-free

Hepatocellular Carcinoma

Taiwan

Search clinical trials for: Metformin placebo

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Cambodia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations