Search clinical trials for: metformin HCl

Total 4863 results

Anna Maria Storniolo
National Cancer Institute (NCI)

Completed

Metformin Hydrochloride vs. Placebo in Overweight or Obese Patients at Elevated Risk for Breast Cancer

Obesity | Breast Cancer

United States
National Cancer Institute (NCI)

Completed

Metformin Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery

Recurrent Prostate Cancer | Stage I Prostate Cancer | Adenocarcinoma of the Prostate | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer

United States
New York Medical College
Albert Einstein College of Medicine; University of Tennessee

Completed

EMPOWIR:Enhance the Metabolic Profile of Women With Insulin Resistance (EMPOWIR)

Obesity | Insulin Resistance | Hyperinsulinemia

United States
GlaxoSmithKline

Completed

BE STUDY OF METFORMIN GSK 1000mg (BA/BE 199/11)

Diabetic Foot
Era's Lucknow Medical College

Completed

Metformin in Overweight Type 2 Diabetes Mellitus

Obesity | Type 2 Diabetes Mellitus

India
Munich Municipal Hospital
Aventis Pharmaceuticals

Unknown

Can Insulin Glargine Improve Myocardial Function in Patients With T2D and Coronary Artery Disease (CAD)

Coronary Artery Disease | Type 2 Diabetes

Germany
Steno Diabetes Center Copenhagen

Completed

Effect of Metformin Versus Repaglinide Treatment in Non-Obese Type 2 Diabetic Patients Uncontrolled by Diet

Diabetes Mellitus, Type 2

Denmark
Kyunghee University Medical Center
Sanofi; Korea University Guro Hospital; Hanyang University; The Catholic University... and other collaborators

Completed

Study To Evaluate Beta Cell Function and Glycemic Outcome by Intensive Insulin Therapy (KIIT)

Type 2 Diabetes Mellitus | Pancreatic Beta Cell Function | Glucotoxicity

Korea, Republic of
Fundación Fernández-Cruz

Withdrawn

A Long-term Trial to Compare the Effects of Liraglutide and Sulphonylurea (Glimepiride) Both in Combination With Metformin on Clinical, Endothelial and Image Markers of Cardiovascular Risk in Patients With Type 2 Diabetes (ADELANTE)

Type 2 Diabetes

Spain
GC Biopharma Corp

Recruiting

A Study to Evaluate the Safety, PK of GC2129A in Healthy Volunteers Under Fed Conditions

Healthy Volunteers

Korea, Republic of
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Fixed Combination Therapy of Vildagliptin and Metformin (25/1000 mg Bid) in Patients With Type 2 Diabetes Inadequately Controlled With Prior Metformin Monotherapy (HbA1c 7.0-9.5%)

Diabetes Mellitus, Type 2

United States, Hungary, Poland, Germany, France
Laboratorios Silanes S.A. de C.V.

Unknown

Sibutramine-metformin Combination Versus Sibutramine and Metformin Monotherapy in Obese Patients

Obesity

Mexico
Amicus Therapeutics

Completed

A 12-Week Safety and Pharmacodynamic Study of AT1001 (Migalastat Hydrochloride) in Female Participants With Fabry Disease

Fabry Disease

United States, Australia, France, United Kingdom, Brazil, Canada
Al-Rasheed University College

Completed

Pyridoxine Effect on the Blood Glucose Level in Type 2 Diabetic Patients

Diabetes Mellitus, Type 2

Iraq
HK inno.N Corporation

Completed

Pharmacokinetic Interactions Between Atorvastatin and Metformin in Healthy Male Subjects

Healthy

Korea, Republic of
Almirall, S.A.
Allergan

Completed

Double-Blind, Placebo-Controlled Study to Evaluate 3 Doses of a Novel Tetracycline in the Treatment of Facial Acne Vulgaris

Acne Vulgaris

United States
Boehringer Ingelheim

Completed

Safety and Efficacy of Linagliptin (BI 1356) Plus Metformin in Type 2 Diabetes, Factorial Design

Diabetes Mellitus, Type 2

Canada, Croatia, Estonia, France, Germany, India, Lithuania, Mexico, Netherlands, Romania, Russian Federation, Sweden, Tunisia, Ukraine
Sheba Medical Center

Completed

Effects of Vildagliptin/Metformin Combination on Markers of Atherosclerosis, Thrombosis, and Inflammation in Diabetics With Coronary Artery Disease (VAAST)

Type 2 Diabetes Mellitus | Ischemic Heart Disease

Israel
VA Office of Research and Development

Recruiting

Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes (VA-IMPACT)

Atherosclerosis | Prediabetic State | Metformin

United States
NYU Langone Health

Completed

Metformin Prostate Cancer Adjuvant Trial

Prostate Cancer | Prostate Cancer Recurrent

United States
Cairo University

Unknown

Cancer Chemoprevention by Metformin Hydrochloride in Oral Potentially Malignant Lesions

Oral Cancer

Egypt
Merck Sharp & Dohme LLC

Completed

A Dose-Range Finding Study in Participants With Type 2 Diabetes (MK-3102-006)

Type 2 Diabetes Mellitus
Ionis Pharmaceuticals, Inc.

Completed

Safety, Tolerability, and Efficacy of ISIS-PTP1BRx in Type 2 Diabetes

Type 2 Diabetes Mellitus | Obese

Argentina, Canada, South Africa
Sanofi

Completed

Insulin Glargine v Rosiglitazone as add-on Therapy in Patients Failing Sulfonylurea and Metformin Combination Therapy

Type 2 Diabetes Mellitus

United States
University of Zambia
University Teaching Hospital, Lusaka, Zambia

Not yet recruiting

Glycaemic & Cardiovascular Treatment Outcomes of Voglibose Vs Glibenclamide Added to Metformin in T2DM Patients (VMGMProtocol)

Diabetes Mellitus Type 2 Without Complication
University of California, Los Angeles

Recruiting

Metformin Treatment in Progressive Multiple Sclerosis

Primary Progressive Multiple Sclerosis | Secondary Progressive Multiple Sclerosis

United States
Dong-A ST Co., Ltd.

Completed

A Clinical Trial to Investigate Safety/Tolerability and Pharmacokinetics of DA-1229_01 Compared to Co-administration of Evogliptin 5 mg and Metformin XR 1000 mg, and to Evaluate the Effect of Food on the Pharmacokinetics of DA-1229_01 in Healthy Male Volunteers

Type 2 Diabetes Mellitus

Korea, Republic of
The Affiliated Hospital of Hangzhou Normal University

Not yet recruiting

Study on MAFLD-related Cirrhosis Prevention and Treatment Strategies (SMART)

Cirrhosis | Metabolic Dysfunction-associated Fatty Liver Disease
PegBio Co., Ltd.

Not yet recruiting

Study to Evaluate the Efficacy and Safety of PB-201 in Type 2 Diabetic Mellitus Patients With Poor Glycemic Control Via Metformin Hydrochloride Monotherapy

Type 2 Diabetes Mellitus

China
Instituto Nacional de Ciencias Medicas y Nutricion...

Completed

Effect of the SCL16A11 Risk Haplotype on Treatments to Prevent Type 2 Diabetes (PRED2)

PreDiabetes

Mexico
Mylan Pharmaceuticals Inc

Completed

Food BE Study Metformin Hydrochloride ER Tablets 500 mg and Glucophage XR 500 mg

Healthy

United States
Dong-A ST Co., Ltd.

Unknown

A Clinical Trial to Evaluate the Preference Regarding Convenience of Medication and Efficacy/Safety of SUGAMET®XR Tablet 5/1000mg

Diabetes Mellitus, Type 2 | Diabetes Mellitus | Endocrine System Diseases | Metabolic Disease | Renal Disease

Korea, Republic of
Takeda

Completed

Special Drug Use Surveillance of Pioglitazone/Metformin Hydrochloride Combination Tablets Survey on Long-term Use for Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus
Instituto Nacional de Cancer, Brazil

Withdrawn

The Use of Metformin in Early Breast Cancer Patients Pre-Surgery

Breast Cancer

Brazil
Samuel Lunenfeld Research Institute, Mount Sinai...
University of Western Ontario, Canada

Completed

A Lifestyle and Combination Medication Therapy Diabetes Prevention Study

Diabetes | Impaired Glucose Tolerance

Canada
National Hepatology & Tropical Medicine Research...

Not yet recruiting

Assessment of Metformin as Adjuvant Therapy in Patients With Ulcerative Colitis

Inflammatory Bowel Diseases | Ulcerative Colitis

Egypt
University Hospital, Lille

Not yet recruiting

Influence of Preprandial Metformin Administration on Carbohydrate Absorption (METTIME)

Type2 Diabetes | Impaired Glucose Tolerance
Shanghai 10th People's Hospital

Completed

Treating PCOS With Digital CBT vs. Metformin

Polycystic Ovary Syndrome

China
Temple University

Completed

Intervention to Promote Weight Loss in Latinas At-risk for Diabetes

Diabetes

United States
Merck Sharp & Dohme LLC

Terminated

A Study of the Safety and Efficacy of MK-3577 in Participants With Type 2 Diabetes Mellitus (MK-3577-009)

Type 2 Diabetes Mellitus
Aarhus University Hospital

Unknown

Metformin Pharmacokinetics in Patients With Chronic and Acute Heart Failure (MetKin)

Heart Failure, Systolic

Denmark
Ottawa Hospital Research Institute
CIHR Canadian HIV Trials Network

Withdrawn

Improving Fibrosis Outcomes With Metformin

HIV Infection | Hepatitis C

Canada
The Hospital for Sick Children

Completed

Hypothalamic Obesity Following Craniopharyngioma Surgery: A Pilot Trial of Combined Metformin and Diazoxide Therapy

Hypothalamic Obesity

Canada
Xiang Guang-da

Unknown

Metformin Induces a Dietary Restriction-like State in Human

Aging | Metformin | Overweight Subjects

China
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Withdrawn

Metformin Hydrochloride in Treating Patients With Pancreatic Cancer That Can be Removed by Surgery

Stage IIA Pancreatic Cancer | Stage IIB Pancreatic Cancer | Stage IA Pancreatic Cancer | Stage IB Pancreatic Cancer
Takeda

Completed

Efficacy of Pioglitazone and Fortamet Combination Therapy in Subjects With Type 2 Diabetes

Diabetes Mellitus
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Effects of Fats on Blood Glucose in People With and Without Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Metformin Hydrochloride Liquid 500mg/ 5 mL Under Fed Conditions

Healthy

Canada
All India Institute of Medical Sciences, Bhubaneswar
Chemical Resources

Completed

Clinical Evaluation of Fenugreek Seed Extract, a Nutraceutical in Patients With Type- 2 Diabetes

Type-2 Diabetes Mellitus

India
AstraZeneca

Completed

Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Saxagliptin as Monotherapy in Pediatric Patients With Type 2 Diabetes

Type 2 Diabetes

United States, Russian Federation, South Africa, Taiwan

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