Search clinical trials for: Metformin extended-release (XR)

Total 917 results

NYU Langone Health

Completed

Metformin Prostate Cancer Adjuvant Trial

Prostate Cancer | Prostate Cancer Recurrent

United States
University of Arizona
National Cancer Institute (NCI)

Recruiting

Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia

Oral Leukoplakia | Erythroplakia

United States, Canada
National Cancer Institute (NCI)

Recruiting

Metformin for Chemoprevention of Lung Cancer in Overweight or Obese Individuals at High Risk for Lung Cancer

Lung Carcinoma

United States, Canada
Gwendolyn Sowa

Completed

Effects of Metformin on Low Back Pain

Low Back Pain

United States
Woman's
Pfizer; American Cancer Society, Inc.; Our Lady of the Lake Regional Medical...

Withdrawn

Metformin Use to Reduce Disparities in Newly Diagnosed Breast Cancer (METBC)

Insulin Resistance | Breast Cancer Stage | Racial Bias

United States
James Wang
United States Department of Defense

Recruiting

Managing Chronic Tendon Pain by Metformin

Chronic Pain | Tendinopathy | Achilles Tendinopathy

United States
Indiana Hemophilia &Thrombosis Center, Inc.

Active, not recruiting

Metformin Use in Cardiac Fibrosis in PAI-1 Deficiency

Plasminogen Activator Inhibitor-1 Deficiency | Cardiac Fibrosis

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

Healthy

United States
Era's Lucknow Medical College

Completed

Metformin in Overweight Type 2 Diabetes Mellitus

Obesity | Type 2 Diabetes Mellitus

India
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin Extended Release Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

Healthy

United States
AstraZeneca

Completed

Bioequivalence Study of Fixed-dose Combinations and Coadministered Individual Tablets of Saxagliptin/Metformin-Brazil

Type 2 Diabetes Mellitus

Brazil
Duke University

Terminated

Metformin for the Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) (NAFLD)

Fatty Liver

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release (XR) With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

Healthy

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Metformin and Nightly Fasting in Women With Early Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Breast Ductal Carcinoma In Situ | Invasive Breast Carcinoma

United States, Italy
Brigham and Women's Hospital
Arthritis Foundation

Recruiting

Preventing Injured Knees From osteoArthritis: Severity Outcomes (PIKASO)

Osteoarthritis, Knee | Post-traumatic Osteoarthritis | ACL Tear

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin XR Tablet Co-administered With Canagliflozin in Healthy Fed and Fasted Participants

Healthy

United States
Methodist Healthcare

Completed

Envarsus XL Immunosuppression Following Liver Transplantation

Recipients of Liver Transplant

United States
LG Life Sciences

Completed

BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 1000mg in Comparison to Each Component Administered Alone

Healthy

Korea, Republic of
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Completed

Effect of Insulin Sensitizer Therapy on Atherothrombotic and Inflammatory Profiles Associated With Insulin Resistance

Metabolic Syndrome | Insulin Resistance | Type 2 Diabetes

United States
LG Life Sciences

Unknown

BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 2000mg in Comparison to Each Component Administered Alone

Healthy

Korea, Republic of
LG Life Sciences

Completed

BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 500mg in Comparison to Each Component Administered Alone

Healthy

Korea, Republic of
IPCA Laboratories Ltd.

Completed

Bioequivalence Study of Metformin Hydrochloride Extended-Release Tablets USP 750 mg Under Fasting Condition

Fasting

India
Johns Hopkins University
Baylor College of Medicine; National Heart, Lung, and Blood Institute (NHLBI); Temple University

Not yet recruiting

Metformin IN Asthma for Overweight and Obese Individuals (MINA)

Asthma | Overweight and Obesity | Asthma Chronic
AstraZeneca

Recruiting

Efficacy of FDC Regimen of Dapagliflozin/Metformin Compared to Co-administered Dual Therapy on Glycemic Control, Satisfaction and Adherence in Chinese Patients With T2DM

Type 2 Diabetes Mellitus (T2DM)

China
IPCA Laboratories Ltd.

Completed

Bioequivalence Study of Metformin Hydrochloride Extended-Release Tablets USP 750 mg Under Fed Condition

Fasting

India
GlaxoSmithKline

Terminated

Crossover Study to Evaluate the Comparative Bioavailability of Two Fixed Dose Combination Tablet Formulations of Extended Release Metformin and Extended Release Glimepiride in Health Volunteers

Diabetes Mellitus, Type 2

Australia
Sandoz

Completed

To Demonstrate the Relative Bioavailability of Metformin HCL 500 mg Extended Release (XR) Tablets Under Fasting Conditions

Type II Diabetes
Pauls Stradins Clinical University Hospital

Completed

Coronary Artery Disease Progression in Patients With Prediabetes

Coronary Artery Disease | Atherosclerosis | Prediabetic State

Latvia
UCB Pharma

Completed

A Study to Look at the Efficacy and Safety of Keppra® Extended Release Formulation - XR

Epilepsy

Brazil, Finland, India, Mexico, Russian Federation, South Africa, Ukraine
Actavis Inc.

Completed

A Relative Bioavailability Study of Metformin HCl 750 mg ER Tablets Under Fasting Conditions

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Metformin HCl 750 mg ER Tablets Under Non-fasting Conditions

Healthy

United States
University of Colorado, Denver

Withdrawn

Oxtellar Extended Release (Oxcarbazepine Extended Release) Patients With Trigeminal Neuralgia

Trigeminal Neuralgia
University of Calgary
AstraZeneca

Completed

Serotonin Transporter Genetic Variation and Amygdala Responses to Antidepressant Medications in Major Depression

Major Depressive Disorder

Canada
LG Life Sciences

Completed

BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 1000mg in Comparison to Each Component Administered Alone.

Healthy

Korea, Republic of
University of Hawaii
National Institute of General Medical Sciences (NIGMS)

Unknown

Metformin for HIV Inflammation

Coronary Artery Disease | HIV

United States
Dexa Medica Group

Completed

Bioequivalence Study of Two Formulations of 500 mg Metformin Extended Release Tablet

Metformin XR BE Study in Healthy Volunteers With Single and Multiple Dose

Indonesia
Trisha Wise-Draper
American Cancer Society, Inc.

Active, not recruiting

Combining Pembrolizumab and Metformin in Metastatic Head and Neck Cancer Patients

Head and Neck Squamous Cell Carcinoma

United States
Matthew Neal MD
Berry Consultants; University of Pittsburgh Medical Center

Completed

REMAP Trial for Optimizing Surgical Outcomes at UPMC (UPMCREMAP)

Aging

United States
Joint Stock Company "Farmak"

Completed

Fed Bioequivalence Study of 2 Metformin 1000 mg Prolonged Release Tablets in 28 Healthy Male and Female Volunteers

Pharmacokinetics

Czechia
Laboratorios Silanes S.A. de C.V.

Completed

Tolerability and Pharmacokinetics of Metformin and Metformin Extended Release (ER)

Healthy

Mexico
University of Stellenbosch
University of Rochester; Fogarty International Center of the National Institute...

Recruiting

A Pilot Study of Metformin to Reduce Cerebrovascular Dysfunction in Participants With HIV and Metabolic Syndrome. (SMART)

Metabolic Syndrome | HIV Seropositivity

South Africa
McMaster University

Completed

Quetiapine Extended Release (XR) for the Treatment of Menopausal Depression

Insomnia | Hot Flashes | Major Depressive Disorder

Canada
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Metformin HCl 750 mg XR Under Fasting Conditions

Healthy

United States
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Metformin HCl 750 mg XR Tablets Under Non Fasting Conditions

Healthy

United States
Columbia University
Boston University; Johns Hopkins University; University of California, Berkeley; University of Miami and other collaborators

Recruiting

Metformin in Alzheimer's Dementia Prevention (MAP)

Mild Cognitive Impairment

United States
Bristol-Myers Squibb

Completed

Phase 4: Investigational Study to Evaluate Metformin XR Monotherapy Versus Metformin IR Monotherapy in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus

South Africa, United States, Canada, Puerto Rico, Hungary, Germany, Czechia, Poland, Romania, United Kingdom
LG Chem

Completed

BE Study of the Combinations of Gemigliptin/Metformin HCl Extended Release 50/1000mg(25/500mg x 2 Tablets) in Comparison to Each Component Administered Alone

Healthy Male Volunteers

Korea, Republic of
Weill Medical College of Cornell University
Agency for Healthcare Research and Quality (AHRQ)

Completed

Trial of an Intervention to Improve Metformin Persistence and Adherence (TreatMet)

Tolerance | Metformin Adverse Reaction

United States
Friends Research Institute, Inc.

Recruiting

Extended Release Naltrexone Versus Extended Release Buprenorphine With Individuals Leaving Jail

Opioid-use Disorder

United States
GlaxoSmithKline

Terminated

Effects Of Rosiglitazone (Extended Release Tablets) On Cerebral Glucose Utilisation And Cognition Alzheimers Disease

Alzheimer's Disease

United Kingdom

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