Search clinical trials for: Methotrexate placebo

Total 55067 results

Blokhin's Russian Cancer Research Center

Recruiting

Neoadjuvant Combination of Doxorubicin, Cisplatin and Methotrexate in Patients Aged 24-40 Years With Primary Bone Tumors

Sarcoma | Neoplasms, Connective and Soft Tissue | Osteosarcoma | Neoplasms, Connective Tissue | Sarcoma of Bone

Russian Federation
Astellas Pharma Korea, Inc.

Completed

A Study Comparing Biologics + Methotrexate With Biologics + Tacrolimus in Patients With Rheumatoid Arthritis (RA)

Rheumatoid Arthritis (RA)

Korea, Republic of
King Edward Medical University

Completed

Methotrexate and Statins With Methotrexate Alone in the Treatment of Rheumatoid Arthritis

Arthritis, Rheumatoid

Pakistan
MidAmerica Neuroscience Research Foundation at...
Biogen; Consultants in Neurology

Completed

Combination Therapy With Avonex and BiMonthly High Dose Intravenous Methotrexate in Multiple Sclerosis (MTX01)

Multiple Sclerosis
Grupo Español de Linfomas y Transplante Autólogo...

Terminated

Cyclosporine Plus Methotrexate or Alemtuzumab

Unrecognized Condition: Mature B or T-cell Neoplasm

Spain, Poland
Trans Tasman Radiation Oncology Group
Australasian Leukaemia and Lymphoma Group

Completed

Idarubicin Based Combined Modality Therapy in Primary CNS Lymphoma

Primary Central Nervous System Lymphoma

Australia, New Zealand
Centro di Riferimento Oncologico - Aviano

Unknown

Chemotherapy and Radiation Therapy in Treating Patients With HIV-Related Primary Central Nervous System Lymphoma

Lymphoma

Italy
Burzynski Research Institute

Withdrawn

Methotrexate With or Without Antineoplaston Therapy in Treating Postmenopausal Women With Advanced Refractory Breast Cancer

Stage IV Breast Cancer | Recurrent Breast Cancer

United States
University of Medicine and Dentistry of New Jersey
Ortho Biotech, Inc.

Terminated

LAMPP Trial for Peripheral and Cutaneous T-Cell Lymphoma

T-Cell Lymphoma

United States
Fred Hutchinson Cancer Center

Completed

Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer

Primary Myelofibrosis | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated... and other conditions

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI); Otsuka America Pharmaceutical

Completed

Allogeneic Hematopoietic Cell Transplantation for Patients With Busulfex-based Regimen (LCCC0510)

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Reduced-Intensity Busulfan and Fludarabine With or Without Antithymocyte Globulin Followed by Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Disease

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm

United States
Singapore National Eye Centre
International Stem Cell Forum

Completed

Thyroid Treatment Trial

Graves Ophthalmopathy

Singapore
Sun Yat-sen University

Recruiting

Modified BFM-95 Regimen as First-Line Chemotherapy in Adults With T- Lymphoblastic Lymphoma

Lymphoma, Lymphoblastic

China
George Washington University

Enrolling by invitation

Methotrexate Treatment of Arthritis Caused by Chikungunya Virus (MARCH)

Investigate the Effect(s) of Methotrexate Treatment on Arthritis Disease Severity

Colombia
Aclaris Therapeutics, Inc.

Completed

Study of ATI-450 Plus Methotrexate (MTX) vs MTX Alone in Patients With Moderate to Severe RA

Rheumatoid Arthritis

United States
GlaxoSmithKline

Withdrawn

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Proof of Mechanism of GSK2618960 in Primary Sjögren's Syndrome (pSS)

Autoimmune Diseases

United Kingdom
Smartfish AS

Completed

Pilot Study of Safety and Tolerability of Nutrifriend Cachexia in COPD Cachexia

Cachexia | COPD

Sweden
Smartfish AS

Completed

Pilot Study of Safety and Tolerability of Nutrifriend Cachexia in NSCLC Cachexia

NSCLC | Cachexia

Italy, Sweden, Croatia, Slovakia
Kuopio University Hospital

Withdrawn

Post-operative Corticosteroid Treatment After Mitral Valve Surgery (MitralPOCS)

Atrial Fibrillation

Finland
Centocor, Inc.
Schering-Plough

Completed

An Efficacy and Safety Study of Golimumab in Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy (GO-FORWARD)

Rheumatoid Arthritis

Australia, Poland, United States, Germany, Argentina, Canada, Korea, Republic of, Chile, New Zealand, Taiwan, Mexico, Hungary
Children's Cancer Group, China
Xiangya Hospital of Central South University; Tongji Hospital; Qilu Hospital... and other collaborators

Active, not recruiting

LBL-2016 for Children or Adolescents in China

Lymphoblastic Lymphoma

China
ISU Abxis Co., Ltd.

Unknown

Exploratory P2 Trial to Evaluate Efficacy and Safety of Clotinab® (Abciximab) in Acute MI Patients

Acute Myocardial Infarction

Korea, Republic of
Genentech, Inc.
Roche Pharma AG

Terminated

A Study of Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Who Don't Have a Response to Anti-TNF-α Therapy (SCRIPT) (SCRIPT)

Rheumatoid Arthritis

United States, Belgium, Canada, Hungary, Argentina, Germany, Spain, Brazil, Poland, Israel, Mexico, Japan, France, Peru, Switzerland, Sweden, Italy, Australia, New Zealand, Panama, Czechia, Netherlands, Slovakia, Slovenia, Taiwan
Bristol-Myers Squibb

Completed

Efficacy and Safety Study of BMS-986142 in Patients With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Japan, Spain, United States, Mexico, Italy, Poland, France, Brazil, Korea, Republic of, Canada, Taiwan, Russian Federation, South Africa, Argentina, Germany, Austria, Netherlands
Hoffmann-La Roche

Completed

A Study to Assess the Effect of Tocilizumab + Methotrexate on Prevention of Structural Joint Damage in Patients With Moderate to Severe Active Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

Finland, France, Italy, Poland, Spain, China, Mexico, South Africa, Denmark, Greece, Puerto Rico, United States, Switzerland, Australia, Norway, Brazil
Galapagos NV

Completed

GLPG0259 Multiple Ascending Dose and Methotrexate Drug-drug Interaction (DDI) in Healthy Subjects

Healthy

Belgium
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Institute of Allergy and Infectious...

Terminated

Donor Peripheral Stem Cell Transplant and Donor Natural Killer Cell Transplant After Total-Body Irradiation, Thiotepa, Fludarabine, and Muromonab-CD3 in Treating Patients With Leukemia or Other Blood Diseases

Myelodysplastic Syndromes | Leukemia | Graft Versus Host Disease

United States
University Hospital, Bordeaux

Recruiting

Combination of Methotrexate and Phototherapy Versus Phototherapy in Adults With Progressive Vitiligo (METVI)

Vitiligo

France
Tongji Hospital
Geneplus-Beijing Co. Ltd.; Chinese Cooperative Group of Liver Cancer (CCGLC)

Recruiting

Combined DEB-TACE, Lenvatinib and Pucotenlimab as Conversion Therapy for Unresectable Intrahepatic Cholangiocarcinoma (CCGLC-012)

Cholangiocarcinoma Non-resectable

China
Gateway Institute for Brain Research

Recruiting

Intranasal Insulin and Glutathione as an Add-On Therapy in Parkinson's Disease (NOSE-PD)

Parkinson Disease

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

Immunoclassification of Psoriasis: a Strategy for Precision Medicine

Psoriasis | Immunoclassification

China
National Cancer Institute, Naples

Completed

ELDA: Elderly Breast Cancer - Docetaxel in Adjuvant Treatment

Breast Cancer

Italy
Guangxi Medical University

Unknown

the Effects and Safety of Idarubicin-strengthened Pretreatment Program and Conventional Busulfan Cyclophosphamide Pretreatment Program on High-risk Acute Myeloid Leukemia Patient (IDBUCY)

Acute Myeloid Leukemia

China
HaEmek Medical Center, Israel

Completed

Low Dose Metronomic Poly-chemotherapy for Metastatic CRC (LDMchemoCRC)

Colorectal Cancer

Israel
Jiangsu Alphamab Biopharmaceuticals Co., Ltd

Completed

Efficacy and Safety Study of KN019 in Rheumatoid Arthritis Patients With an Inadequate Response to Methotrexate

Rheumatoid Arthritis

China
Instituto de Medicina Molecular João Lobo Antunes
Merck Sharp & Dohme LLC

Completed

Efficacy of Golimumab in Combination With Methotrexate (MTX) Versus MTX Monotherapy, in Improving Dactylitis, in MTX naïve Psoriatic Arthritis Patients (GO-DACT)

Psoriatic Arthritis

Portugal
Modern Biosciences Ltd
Covance

Completed

Safety and Tolerability Study of MBS2320 in Healthy Subjects and Subjects With Rheumatoid Arthritis

Arthritis, Rheumatoid

United Kingdom
Hoffmann-La Roche
Biogen

Completed

A Study to Evaluate the Safety and Efficacy of MabThera (Rituximab) in Combination With Methotrexate (MTX) in Participants With Active Rheumatoid Arthritis Who Failed on Anti-Tumor Necrosis Factor Alpha Therapy

Rheumatoid Arthritis

Belgium, France, Germany, Norway, United Kingdom, United States, Ireland, Canada, Israel, Netherlands, Italy
Bristol-Myers Squibb

Completed

A Phase III Study of Abatacept in Patients With Rheumatoid Arthritis and an Inadequate Response to Methotrexate

Rheumatoid Arthritis

Korea, Republic of
4SC AG

Completed

SC12267 (4SC-101) in Combination With Methotrexate in Patients With Rheumatoid Arthritis (COMPONENT)

Rheumatoid Arthritis

Bulgaria, Czech Republic, Poland, Romania
University of Aarhus

Completed

Effect of Obeticholic Acid on Transport of Bile Acids in PBC Examined by 11C-cholyl-sarcosine PET/CT

Primary Biliary Cirrhosis

Denmark
Chinese PLA General Hospital

Unknown

Cell Therapy in Patients With Chronic Ischemic Heart Disease Undergoing Cardiac Surgery

Left Ventricular Dysfunction | Chronic Myocardial Ischemia | Old Myocardial Infarction

China
Sinocelltech Ltd.

Unknown

SCT-I10A Plus Standard Chemotherapy in First-line Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma

China
National Cancer Institute (NCI)

Completed

Busulfan, Fludarabine Phosphate, and Anti-Thymocyte Globulin Followed By Donor Stem Cell Transplant and Azacitidine in Treating Patients With High-Risk Myelodysplastic Syndrome and Older Patients With Acute Myeloid Leukemia

Acute Myeloid Leukemia | Recurrent Adult Acute Myeloid Leukemia | Myelodysplastic Syndrome | Myelodysplastic Syndrome With Excess Blasts | Secondary Myelodysplastic Syndrome | de Novo Myelodysplastic Syndrome | Adult Acute Monoblastic Leukemia | Adult Acute Monocytic Leukemia | Adult Acute Myeloid Leukemia... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Fludarabine, Bendamustine, and Rituximab in Treating Participants With Lymphoid Cancers Undergoing Stem Cell Transplant

Follicular Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Recurrent Diffuse Large B-Cell Lymphoma | CD20 Positive | T-Cell Non-Hodgkin Lymphoma

United States
NextCell Pharma Ab

Completed

Wharton´s Jelly Derived Mesenchymal Stromal Cell Treatment of Adult Patients Diagnosed With Type I Diabetes

Type1 Diabetes Mellitus

Sweden
Hui Bu

Not yet recruiting

Efficacy and Safety of Recombinant Human Endostatin in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis

Leptomeningeal Metastasis
Sun Yat-sen University

Completed

Metronomic Chemotherapy in a Real-world Population of Advanced Breast Cancer Patients

Breast Cancer

China
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

High-Dose Methotrexate and Leucovorin in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States

Search clinical trials for: Methotrexate placebo

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