Search clinical trials for: Metoprolol controlled release (CR)

Total 137 results

Hamilton Health Sciences Corporation
National Health and Medical Research Council, Australia; Canadian Institutes... and other collaborators

Terminated

POISE Trial: Perioperative Ischemic Evaluation Study (POISE)

Cardiovascular Diseases

Canada
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A 5-treatment, Study in Healthy Volunteers to Assess The Safety, Tolerability, and Pharmacokinetics of Four Controlled Release (CR) Pregabalin Tablet Formulations and the Immediate Release (IR) Formulation Administered Fasted

Healthy

Belgium
GlaxoSmithKline

Completed

Clinical Evaluation of Ropinirole CR-RLS ( SK&F101468)Tablets in Restless Legs Syndrome

Restless Legs Syndrome

Japan
Pfizer

Completed

A Single Dose Crossover Study In Healthy Subjects To Evaluate Different Formulations Of PF-06882961

Healthy Subjects

United States
Alza Corporation, DE, USA

Completed

A Study on Efficacy (Effectiveness), Safety, and Impact on Quality of Life Measures of Dilaudid CR (Controlled Release);, Hydromorphone HCl in Patients With Chronic Low Back Pain

Low Back Pain
GlaxoSmithKline

Completed

Converting From Ropinirole Immediate Release (IR) To Ropinirole Controlled-Release for RLS (Restless Legs Syndrome)

Restless Legs Syndrome | Restless Legs Syndrome (RLS)

United States
Pfizer

Withdrawn

A Study to Evaluate the Safety and Efficacy of Three Doses of a Controlled Release Formulation of Varenicline for Smoking Cessation

Smoking Cessation
University Hospital Bispebjerg and Frederiksberg

Recruiting

Two Modes of Mechanical Ventilation for Intensive Care Patients With Low Blood Oxygen Due to Breathing Difficulties

Hypoxic Respiratory Failure | Ventilators, Mechanical

Denmark
GlaxoSmithKline

Completed

Onset Motor Complications Using REQUIP CR (Ropinirole Controlled-release) As Add-on Therapy To L-dopa In Parkinson's

Parkinson's Disease | Parkinson Disease | Dyskinesias

United States
NLS Pharmaceutics

Not yet recruiting

A Eight-Week Study of NLS-2 (Mazindol Extended Release) in Participants With Narcolepsy Type 1 (AMAZE)

Narcolepsy Type 1 | Narcolepsy With Cataplexy
Zogenix, Inc.

Completed

Long-Term Study of Hydrocodone Bitartrate Controlled-release Capsules in Subjects With Chronic Pain

Chronic Pain

United States
GlaxoSmithKline

Completed

Use of Beta-blockers and Risk of New Onset Diabetes

Hypertension
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Terminated

A Long-term Safety Study With Tapentadol ER and Oxycodone CR in Patients With Moderate to Severe Pain Due to Chronic, Painful Diabetic Peripheral Neuropathy (DPN)

Diabetic Neuropathy, Painful | Diabetic Polyneuropathy

United States
Shandong Branden Med.Device Co.,Ltd
Fudan University

Unknown

Comparing the Safety and Efficacy of Paclitaxel Controlled Release Balloon Catheter in the Treatment of In-stent Restenosis of Coronary Artery Lesion With Paclitaxel Release Coronary Balloon Catheter

In-stent Restenosis

China
Janssen Research & Development, LLC

Withdrawn

A Crossover Study to Evaluate the Effect of JNJ-54452840 on Pharmacodynamics of Metoprolol Tartrate Immediate-Release in Healthy Participants

Healthy

United States
University of Florida
Food and Drug Administration (FDA)

Completed

Open-Labeled PK-PD Studies of Metoprolol ER

Blood Pressure

United States
University of Tennessee, Chattanooga

Withdrawn

Airway Pressure Release Ventilation (APRV) Compared to ARDSnet Ventilation (PRESSURE)

Acute Lung Injury | Kidney Injury | Adult Respiratory Distress Syndrome

United States
Purdue Pharma LP

Completed

A Study of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain

Low Back Pain

United States
Mahidol University

Not yet recruiting

The Study of Efficacy and Safety of Generic Methylphenidate Prolong-released Comparison With Original

Adhd
Emalex Biosciences Inc.
Psyadon Pharma

Completed

Safety and Tolerability Comparison of Immediate and Controlled Release Formulations of Ecopipam

Healthy

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

An Investigation of the Absorption and Pharmacokinetics of Multiple Doses of Three Controlled Release Pregabalin Tablets as Compared to Multiple Doses of the Immediate Release Pregabalin Capsule

Healthy

Belgium
Purdue Pharma LP

Completed

Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) for Uncontrolled Moderate - Severe Low Back Pain

Low Back Pain

United States, Poland, Czech Republic, Italy
University of Calgary
Ferring Pharmaceuticals

Not yet recruiting

Efficacy and Safety of Budesonide MMX® vs. Budesonide CR for Induction of Remission in Microscopic Colitis

Microscopic Colitis
Abbott

Completed

A Study of Pain Relief in Low Back Pain

Chronic Low Back Pain

United States
CTI-1, LLC
GlaxoSmithKline; CTI Clinical Trial and Consulting Services

Completed

A Study to Compare the Effects of Coreg CR and Coreg IR on Heart Function in Subjects With Stable Chronic Heart Failure (COMPARE)

Congestive Heart Failure

United States
European Organisation for Research and Treatment...

Completed

Surgery and BCG in Treating Patients With Bladder Cancer

Bladder Cancer

Netherlands, Belgium, France, Austria, United Kingdom, Israel, Italy, Turkey, Greece, Portugal, Romania
Impax Laboratories, LLC

Completed

Comparison of IPX054, IR Carbidopa-Levodopa, and CR Carbidopa-Levodopa in Subjects With Parkinson's Disease

Idiopathic Parkinson's Disease

United States
State University of New York - Downstate Medical...

Unknown

Coreg CR, Blood Vessel Stiffness and Blood Vessel Function

Hypertension | Diabetes Mellitus | Endothelial Function

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

An Investigation Of The Absorption And Pharmacokinetics Of A Single Dose Of A Controlled Release (CR) Pregabalin Tablet Following A Low, Medium, And High-Fat Evening Meal As Compared To A Single Dose Of The Immediate Release (IR) Pregabalin Capsule In Healthy Volunteers

Healthy

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Investigation Of Absorption And Pharmacokinetics Of A Single Dose Of Controlled Release Pregabalin Tablet Administered Fasted At Bedtime Or Immediately Following A 400-500 or 600-750 Calorie Evening Meal As Compared To Single Dose Of Immediate Release Pregabalin Capsule In Healthy Volunteers

Healthy

United States
Synerx Pharma, LLC

Completed

Comparative Bioavailability Study of Synerx and Verelan PM 300 mg Verapamil HCl ER Capsules Under Fed Conditions

Healthy
The Rogosin Institute

Terminated

Combined Renin Inhibition/Beta-blockade

Hypertension

United States
University Health Network, Toronto
Canadian Society of Hospital Pharmacists

Withdrawn

Dosing Intervals of Opioid Medication for Chronic Pain

Chronic Pain

Canada
University Hospital Schleswig-Holstein

Completed

Safety and Pharmacokinetics of Oral Controlled-ileocolonic-release Nicotinamide (CICR-NAM)

Safety Issues | Pharmacokinetic

Germany
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

An Investigation Of The Absorption And Pharmacokinetics Of A Single Dose Of A Controlled Release (CR) Pregabalin Tablet Following Various Sized Lunches As Compared To A Single Dose Of The Immediate Release (IR) Pregabalin Capsule In Healthy Volunteers

Healthy

United States
Research Foundation for Mental Hygiene, Inc.
National Institute of Mental Health (NIMH)

Completed

Combination Treatment for Posttraumatic Stress Disorder (PTSD) After the World Trade Center (WTC) Attack

Posttraumatic Stress Disorder

United States
University at Buffalo
GlaxoSmithKline

Terminated

Vascular Benefits of Adding CarvedilolCR to Type2 Diabetic Patients on ACEI.

Hypertension | Diabetes Mellitus, Type 2

United States
University of Parma

Terminated

Controlled-Release Oxycodone For Postoperative Analgesia After Video-Assisted Thoracic Surgery

Pain, Postoperative | Anesthesia Recovery Period

Italy
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

An Investigation Of The Absorption And Pharmacokinetics Of Multiple Doses Of Two Controlled Release Pregabalin Tablets As Compared To Multiple Doses Of The Immediate Release Pregabalin Capsule

Healthy

Belgium
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

An Investigation Of The Absorption And Pharmacokinetics Of Multiple Doses Of Two Controlled Release Pregabalin Tablets As Compared To Multiple Doses Of The Immediate Release Pregabalin Capsule In Healthy Volunteers

Healthy

Belgium
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Paroxetine Hydrochloride Controlled-Release Tablets 25 mg to Paxil CR™ Tablets 25 mg

Healthy

United States
UCB Pharma

Completed

Levetiracetam Versus Standard Antiepileptic Drugs (Carbamazepine and Valproate) Used as Monotherapy in Patients With Newly Diagnosed Epilepsy

Epilepsy

Australia, France, Germany, Italy, Poland, United Kingdom, Belgium, Spain, Switzerland, Austria, Bulgaria, Romania, Turkey, Denmark, Greece, Russian Federation, Netherlands, Hungary, Ireland, Slovakia, Sweden, Norway, Finland, Czech Republic
Sumitomo Pharma (Suzhou) Co., Ltd.

Completed

Efficacy and Safety of Arotinolol Hydrochloride on Morning Blood Pressure and Heart Rate (ESAHOM)

Essential Hypertension

China
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Investigation Of Absorption And Pharmacokinetics Of A Single Dose Of Controlled Release Pregabalin Tablet Administered Fasted In The Evening or Immediately Following A 600-750 Calorie Evening Meal As Compared To Single Dose Of Immediate Release Pregabalin Capsule In Healthy Volunteers

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study of Paroxetine Hydrochloride Controlled-Release Tablets 25 mg to Paxil CR™ Tablets 25 mg

Healthy

United States
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Phase Ⅲ Study of Extended-Release Carvedilol Sulfate for the Treatment of Heart Failure

Heart Failure

China
University of Rochester NCORP Research Base
National Cancer Institute (NCI)

Recruiting

Bupropion to Reduce Cancer Related Fatigue in Cancer Survivors

Be Diagnosed With Cancer and Have Completed Systemic Therapy

United States
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Phase Ⅲ Study of Extended-Release Carvedilol Sulfate for the Treatment of Hypertension

Hypertension

China
Pfizer

Completed

A Randomized, Two-way, Crossover Study to Estimate the Relative Bioavailability of a Controlled-release Formulation of Oxycodone (40 mg) With Sequestered Naltrexone Compared With Immediate-release Oxycodone Tablets (20 mg) in Healthy Volunteers

Healthy

United States
Intec Pharma Ltd.

Unknown

Study to Assess Pharmacokinetics of Accordion Pill Carbidopa-Levodopa Compared to Immediate Release Carbidopa-Levodopa in Parkinson's Disease Patients

Parkinson Disease

3

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