Search clinical trials for: NaCl-saline placebo

Total 64089 results

University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of Hypertonic Saline on Mucus Clearance in Children Ages 5-12 With Cystic Fibrosis

Cystic Fibrosis

United States
Hamilton Health Sciences Corporation

Completed

Hypotonic Versus Isotonic Parenteral (HIP) Fluid Trial

Hyponatremia | Hypernatremia

Canada
Karolinska Institutet
Danderyd Hospital

Completed

Endotoxin-induced Inflammatory and Behavioral Responses and Predictors of Individual Differences

Sickness Behavior
Laureate Institute for Brain Research, Inc.

Terminated

Influenza Challenge in Mood Disorders

MAJOR DEPRESSIVE DISORDER

United States
Hospital General de Niños Pedro de Elizalde

Completed

Variation in Natremia Using Two Different Maintenance Intravenous Fluids in Postsurgical Hospitalized Children (surgical-Na)

Hyponatremia

Argentina
Noveome Biotherapeutics, formerly Stemnion

Completed

Safety, Efficacy and Treatment Regimen Study of ST266 in Subjects With Moderate to Severe Periodontitis

Periodontal Disease

United States
University Hospital Inselspital, Berne

Completed

Hypertonic Saline for Fluid Resuscitation After Cardiac Surgery (HERACLES)

Cardiovascular Diseases | Valvular Heart Disease

Switzerland
Ahmed Mohamed ELbadawy

Unknown

Prophylaxis Versus Treatment for TURP Syndrome.

Transurethral Resection of Prostate Syndrome

Egypt
University of Haifa
Western Galilee Hospital-Nahariya

Recruiting

Physiological, Cognitive, and Personal Features in the Link Between Placebo-effect and Variability of Pain Reports

Chronic Back Pain

Israel
Regional Hospital Holstebro

Completed

Effect of Hypertonic Sodium Chloride on Urinary Biomarkers in Healthy Subjects and Patients With Chronic Kidney Disease (CASE)

Nephropathy

Denmark
Vasopharm GmbH

Completed

Phase 2 a Study to Assess Safety and Pharmacokinetics of VAS203 in Patients With Traumatic Brain Injury (NOSTRA)

Traumatic Brain Injury

Austria, France, Spain, Switzerland, United Kingdom
Stefania La Grutta, MD

Completed

Effects of Hypertonic Saline Solution (NACL 3%+NAHCO3) on Nasal Inflammation in Children With AR. RinASol- Pilot Study (RinASol)

Allergic Rhinitis

Italy
Marinomed Biotech AG

Completed

Efficacy and Safety Evaluation of Inhaleen Inhalation in Hospitalized COVID-19 Patients

Covid19

Austria
MiMedx Group, Inc.

Completed

Micronized dHACM Injectable for the Treatment of Plantar Fasciitis (dHACM)

Fasciitis, Plantar

United States
University of Arkansas, Fayetteville
Danone Research

Completed

The Effect of Vasopressin on Glucose Regulation (HYPERGlu)

Insulin Resistance

United States
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Hypertonic Saline Solution in Heart Failure

Heart Failure | Renal Failure | Hyponatremia

Brazil
PepTcell Limited
Norwegian Institute of Public Health; University Medical Center Groningen; University... and other collaborators

Completed

A Randomised, Double-blind, Placebo-controlled Phase IIb Trial to Test FLU-v Vaccine

Influenza

Netherlands
Arrowhead Pharmaceuticals

Completed

Study of ARO-ANG3 in Healthy Volunteers and in Dyslipidemic Patients

Dyslipidemias | Hypertriglyceridemia | Familial Hypercholesterolemia

Australia, New Zealand
Arrowhead Pharmaceuticals

Completed

Study of ARO-APOC3 in Healthy Volunteers, Hypertriglyceridemic Patients and Patients With Familial Chylomicronemia Syndrome (FCS)

Hypertriglyceridemia | Familial Chylomicronemia

Australia, Canada, New Zealand
Alnylam Pharmaceuticals

Completed

A Phase 1/2 Study of an Investigational Drug, ALN-CC5, in Healthy Adult Volunteers and Patients With PNH

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Spain, United Kingdom
Alnylam Pharmaceuticals

Completed

ENDEAVOUR: Phase 3 Multicenter Study of Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC)

Amyloid Neuropathies | Amyloid Neuropathies, Familial | Amyloidosis, Hereditary | Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC) | Amyloidosis, Hereditary, Transthyretin-Related | Familial Transthyretin Cardiac Amyloidosis

United States, France, Italy, Spain, Canada, Germany, Belgium, Sweden, United Kingdom
Alnylam Pharmaceuticals

Completed

A Phase 1 Study of Givosiran (ALN-AS1) in Patients With Acute Intermittent Porphyria (AIP)

Acute Intermittent Porphyria

United States, United Kingdom, Sweden
Alnylam Pharmaceuticals

Completed

A Safety and Tolerability Study of an Investigational Drug, ALN-TTRSC02, in Healthy Subjects

Transthyretin-mediated Amyloidosis (ATTR Amyloidosis)

United Kingdom
Alnylam Pharmaceuticals
The Medicines Company

Completed

A Phase 1 Study of an Investigational Drug, ALN-PCSSC, in Subjects With Elevated Low Density Lipoprotein Cholesterol (LDL-C)

Hypercholesterolemia

United Kingdom
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety, Tolerability, and Parmacokinetics of ALN-TTR02 in Healthy Volunteer Subjects

TTR-mediated Amyloidosis

United Kingdom
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety and Tolerability of ALN-PCS02 in Subjects With Elevated LDL-Cholesterol (LDL-C)

Elevated LDL-Cholesterol (LDL-C)

United Kingdom
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety and Tolerability of ALN-TTR01 in Transthyretin (TTR) Amyloidosis

Transthyretin Mediated Amyloidosis (ATTR)

United Kingdom, France, Portugal, Sweden
Medical Centre Leeuwarden

Completed

The Effect of Nitroglycerine on Microcirculatory Abnormalities During Sepsis (NISMIS)

Sepsis | Septic Shock

Netherlands
NuvOx LLC

Recruiting

A Phase 2 Study of NanO2(TM) Combined With Radiation and Temozolomide in Patients With Newly Diagnosed GBM (RESTORE)

Glioblastoma Multiforme

United States
Alnylam Pharmaceuticals

Active, not recruiting

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

United States, Poland, Argentina, Australia, Belgium, France, Germany, Japan, Netherlands, Portugal, Spain, Sweden, United Kingdom, Canada, Czechia, Denmark, Hungary, Ireland, Norway, Korea, Republic of, Austria, Croatia, Israel, Latvia, Lithuan... and more
Universitas Bali Internasional

Completed

The Effects of Intra-articular Platelet-Rich Plasma Injection on The Severity of Knee Osteoarthritis

Osteoarthritis, Knee

Indonesia
Arrowhead Pharmaceuticals

Completed

Study of ARO-HSD in Healthy Volunteers and Patients With Non-Alcoholic Steatohepatitis (NASH) or Suspected NASH

Non-alcoholic Steatohepatitis

New Zealand
Dicerna Pharmaceuticals, Inc.

Completed

Study to Evaluate Safety, Tolerability, PK and PD of DCR-PHXC in PH Type 3 Patients (PHYOX4)

Primary Hyperoxaluria Type 3

United States, Germany, Netherlands, United Kingdom
Alnylam Pharmaceuticals

Completed

A Study of the Safety, Tolerability and Pharmacokinetics of ALN-TTR02 in Japanese Healthy Volunteers

Transthyretin (TTR)-Mediated Amyloidosis

United Kingdom
Ionis Pharmaceuticals, Inc.
Akcea Therapeutics

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS APO(a)-LRx in Healthy Volunteers With Elevated Lipoprotein(a)

Elevated Lipoprotein(a)

Canada
Alnylam Pharmaceuticals

Completed

APOLLO: The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis

Amyloid Neuropathies | Amyloid Neuropathies, Familial | TTR-mediated Amyloidosis | Amyloidosis, Hereditary | Amyloidosis, Hereditary, Transthyretin-Related | Familial Amyloid Polyneuropathies

United States, Canada, Argentina, Australia, Bulgaria, Cyprus, Italy, Japan, Malaysia, Mexico, Netherlands, Portugal, Spain, Sweden, Germany, France, Brazil, Turkey, Korea, Republic of, Taiwan, United Kingdom
Alnylam Pharmaceuticals

Completed

A Phase 1, Single- and Multi-Dose, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered ALN-TTRSC (Revusiran) in Healthy Volunteers

TTR-mediated Amyloidosis

United Kingdom
Radboud University Medical Center
Exponential Biotherapies Inc.

Unknown

Immunomodulation of EA-230 Following On-pump Coronary Artery Bypass Grafting (CABG) (EASI)

Systemic Inflammatory Response Syndrome | Coronary Artery Bypass Grafting

Netherlands
MiMedx Group, Inc.

Completed

Micronized dHACM Injectable for the Treatment of Plantar Fasciitis

Fasciitis, Plantar

United States
Ospedale Regionale di Lugano
Rijnstate Ziekenhuis, Arnhem, The Netherlands; Paolo Maino, Sponsor-Investigator

Recruiting

RCT Study of the Gelstix™ Device to Treat Chronic Discogenic Low Back Pain GelStix Study (GelStix)

Degeneration of Lumbar Intervertebral Disc

Switzerland, Netherlands
MiMedx Group, Inc.

Completed

Micronized dHACM Injectable for the Treatment of Achille Tendonitis

Tendonitis;Achilles

United States
Assistance Publique - Hôpitaux de Paris

Completed

Ilomedin in Septic Shock With Persistent Microperfusion Defects (I-MICRO) (I-MICRO)

Septic Shock Hyperdynamic

France
Rawalpindi Medical College

Completed

Effect of Hot Saline Irrigation on the Operative Field During Endoscopic Sinus Surgery

Rhinosinusitis

Pakistan
Atox Bio Ltd
Biomedical Advanced Research and Development Authority

Completed

Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections (ACCUTE)

Necrotizing Fasciitis | Necrotizing Soft Tissue Infections | Fournier's Gangrene

United States, France
IRCCS National Neurological Institute "C. Mondino...
University of Pavia

Recruiting

Habituation of the Nociceptive Blink Reflex in Experimentally Induced Migraine Attack

Pain | Migraine | Migraine Disorders

Italy
Ho Cheol Shin, M.D., Ph.D.
Green Cross Corporation; Ajou University School of Medicine; Symyoo

Completed

Investigator Initiated Clinical Study to Explore the Efficacy and Safety of Human Placenta Hydrolysate in the Chronic Fatigue Patients

Chronic Fatigue Syndrome | Idiopathic Chronic Fatigue

Korea, Republic of
Mette Zander
Hvidovre University Hospital

Completed

Effect of Intact GLP-1 (7-36) and GLP-1 Metabolite (9-36) on Coronary and Peripheral Vascular Function in Adults

Coronary Microvascular Dysfunction

Denmark
Medical University of Silesia

Completed

The Platelet-Rich Plasma in the Therapy of Temporomandibular Disorders (PRP/TMD)

Myalgia | Bruxism | Temporomandibular Disorder | PRP

Poland
Radboud University Medical Center
Dutch Kidney Foundation

Recruiting

Salt Supplementation in Gitelman Syndrome

Gitelman Syndrome

Italy, Netherlands
Meshalkin Research Institute of Pathology of Circulation

Completed

The Efficacy and Safety of Hypertonic Saline in Cardiac Surgery Patients. (ESHHS)

Coronary Artery Disease | Edema

Russian Federation

Search clinical trials for: NaCl-saline placebo

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