Search clinical trials for: Naloxone HCl PR tablets

Total 213 results

Develco Pharma Schweiz AG

Unknown

Naloxone HCl PR Tablets in Patients With Opioid Induced Constipation (Naxos)

Opioid-Induced Constipation

United Kingdom, Bulgaria, Czechia, Germany, Poland, Portugal, Serbia, Slovakia, Spain
Mundipharma Research GmbH & Co KG

Completed

Optimisation of Hydromorphone - Naloxone Ratio for the Treatment of Pain (HMX3501)

Constipation

Romania, Switzerland, Israel, Belgium, Germany, Australia, Austria, Czech Republic, Denmark, Finland, France, Netherlands, Poland, United Kingdom
Mundipharma Research GmbH & Co KG

Completed

A Study to Demonstrate Improvement in Symptoms of Constipation in Subjects That Require Around-the-clock Opioid Pain Killer Therapy

Pain | Constipation

United Kingdom
Mundipharma SAS

Terminated

Efficacy of Oxycodone/Naloxone(OXN), Versus Oxycodone (OXY), for the Reduction of Intensity of Opioid-induced Constipation in Pain Patients (OXN3505)

Pain | Constipation

France
Grünenthal GmbH

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GRT9906 Prolonged Release Tablets After Dose Escalation in Healthy Subjects

Pharmacokinetics

Germany
Mundipharma Research GmbH & Co KG

Completed

Oxycodone/Naloxone Prolonged Release (OXN PR) Compared to Placebo to Demonstrate Improvement in Symptoms of Restless Legs Syndrome (RLS) in Subjects With Moderate to Severe Idiopathic RLS With Daytime Symptoms

Moderate to Severe Idiopathic RLS With Daytime Symptoms

Spain, Sweden, Germany
Mundipharma Research GmbH & Co KG

Completed

OXN PR Compared to OxyPR to Demonstrate Non-inferiority in Pain & Locomotor Function & Improvement in Symptoms of Constipation in OA Subjects

Chronic Osteoarthritis

Spain, Belgium, Finland, Czechia, Germany, Hungary
INSYS Therapeutics Inc

Completed

A Study to Compare Bioavailability of Naloxone Nasal Spray, Naloxone Hydrochloride (HCl) Intravenous (IV) and Intramuscular Injection (IM) in Healthy Volunteers

Healthy Volunteer

United States
Mundipharma Oy

Completed

OXN PR Compared to OXY PR in Subjects With Postoperative Pain After Knee Arthroplasty (OXN4505)

Post Operative Pain

Finland
Mundipharma Research GmbH & Co KG

Completed

A Study to Explore the Influence of Two Opioid Pain Medications on Bacterial Composition in the Gut and Other Gastrointestinal Aspects

Severe Chronic Pain

Germany
University of New Mexico

Not yet recruiting

Nalmefene vs Naloxone for the Treatment of Recurrent Respiratory Depression After Opioid Overdose

Opioid Overdose | Opiate Overdose

United States
NanoSHIFT LLC

Completed

Study to Assess the PK Profile of NanoBUP Capsules Relative to Suboxone

Healthy

United States
INSYS Therapeutics Inc

Completed

A Study to Compare Bioavailability of Naloxone Nasal Spray and Naloxone Hydrochloride (HCl) Intramuscular Injection (IM) in Healthy Volunteers

Healthy Volunteer

United States
Indivior Inc.

Completed

Pharmacokinetics, Safety, and Tolerability of Depot Buprenorphine at Three Different Molecular Weights in Treatment-Seeking Subjects With Opioid Use Disorder

Opioid Use Disorder

United States
Grünenthal GmbH

Completed

A Clinical Study in Healthy Women Which Aims to Explore the Intestinal Uptake of Two Different Tablets of GRTA9906 Into the Body and the Effect of Food on it

Pain | Chronic Pain | Neuropathic Pain | Visceral Pain

Germany
Kubota Vision Inc.

Completed

Pharmacokinetic and Pharmacodynamic Study of Emixustat in Subjects With Geographic Atrophy Associated With Dry Age-Related Macular Degeneration

Age-Related Macular Degeneration | Geographic Atrophy

United States
Mundipharma (China) Pharmaceutical Co. Ltd

Completed

Determine the Safety and Efficacy of Oxy/Nal Tablets Compared to Oxy PR in Subjects With Cancer Pain

Pain | Cancer

China
Indivior Inc.

Completed

Transfer of Subjects From Subutex/Suboxone to RBP-6300

Opioid Related Disorder

Austria, Czech Republic, Germany, Sweden
University of Southern California

Not yet recruiting

Ketamine HCl Prolonged Release Oral Tablets for CRPS

Complex Regional Pain Syndromes

United States
Helsinn Healthcare SA

Completed

A Study to Evaluate the Efficacy and Safety of Anamorelin HCl for the Treatment of Malignancy Associated Weight Loss and Anorexia in Adult Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer | Cachexia; Cancer

United States, Croatia, Australia, Belgium, Russian Federation, Poland, Romania, Ukraine
Orexo AB
Worldwide Clinical Trials

Completed

Multi-Center, Open-Label, 24-Week Study of OX219 Safety and Efficacy for Maintenance Treatment of Opioid Dependence

Opioid Dependence, on Agonist Therapy

United States
Gedeon Richter Plc.

Completed

Cariprazine: Comparison of Slow- and Immediate-release Forms

Pharmacokinetic Profile

United Kingdom
Adamas Pharmaceuticals, Inc.

Terminated

Efficacy and Safety of Amantadine Hydrochloride (HCl) ER Tablets to Treat Parkinson's Disease Patients With LID. (ALLAY-LID-I)

Parkinson's Disease | Levodopa Induced Dyskinesias (LID)

France, Spain, Germany, Canada, United States
Mundipharma Research GmbH & Co KG

Completed

OXN PR vs Placebo in Opioid-naive Subjects Suffering From Severe Pain Due to Bladder Pain Syndrome (BPS)

Pain | Interstitial Cystitis | Painful Bladder Syndrome

Poland, Germany, Hungary, Czechia, United Kingdom
Daiichi Sankyo, Inc.

Completed

A Study to Determine the Effect of WelChol Tablets on Cholesterol in Patients Who Have Been Taking Atorvastatin for at Least 4 Weeks.

Hypercholesterolemia

United States
Mundipharma (China) Pharmaceutical Co. Ltd

Completed

OXN PR Tablet 5/2.5 mg and20/10 mg PK Study in Chinese Moderate to Severe Chronic Non-malignant Patients

Chronic Pain

China
Seoul National University Hospital
Kuhnil Pharmaceutical Co., Ltd.

Unknown

Efficacy and Safety of Melatonin PR and Clonazepam in Patients With REM Sleep Behavior Disorder in Parkinson Disease

Parkinson Disease | REM Sleep Behavior Disorder

Korea, Republic of
University of Vermont

Unknown

Interim Buprenorphine Treatment to Bridge Waitlist Delays: Stage II Evaluation

Opioid-use Disorder

United States
Orexo AB
Worldwide Clinical Trials

Completed

Study to Assess Efficacy and Safety of BNX Sublingual Tablets for the Induction of Treatment of Opioid Dependence

Opioid-Related Disorders | Opiate Dependence

United States
Daiichi Sankyo, Inc.

Completed

A Study to Determine the Effect of WelChol Tablets on Cholesterol in Patients Who Have Been Taking Simvastatin for at Least 4 Weeks.

Hypercholesterolemia

United States
Humanis Saglık Anonim Sirketi
Novagenix Bioanalytical Drug R&D Center; Farmagen Ar-Ge Biyot. Ltd. Sti

Completed

Bioequivalence Study of Feniramidol HCl 400 mg Film Tablet (Pharmactive, Turkey) Under Fed Conditions (PHENYRAMIDOL)

Bioequivalence

Turkey
Indivior Inc.

Completed

Usability of Zubsolv Sublingual Tablets 5.7/1.4 to Suboxone Sublingual Film 8/2 In Buprenorphine/Naloxone Treated Opioid Dependent Population

Opioid Dependence

United States
Yale University
National Institute on Drug Abuse (NIDA); Howard University; George Mason University

Completed

HIV, Buprenorphine, and the Criminal Justice System (STRIDE)

Acquired Immunodeficiency Syndrome | Human Immunodeficiency Virus | Opiate Addiction | Drug Dependence

United States
Purdue Pharma LP

Completed

Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) for Uncontrolled Moderate - Severe Low Back Pain

Low Back Pain

United States, Poland, Czech Republic, Italy
Mundipharma (China) Pharmaceutical Co. Ltd

Completed

Targin for Non-cancer Pain

Non Cancer Pain

China
Purdue Pharma LP

Completed

A Study of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain

Low Back Pain

United States
Mundipharma Research GmbH & Co KG

Completed

Oxycodone-naloxone Prolonged Release Tablets in Relieving Opioid-related Constipation

Pain
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Pioglitazone HCl Tablets 45 mg and Actos® Tablets 45 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study of Pioglitazone HCl Tablets 45 mg to Actos® Tablets 45 mg

Healthy

United States
Trevi Therapeutics

Completed

Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritus

Pruritus | Uremic Pruritus

United States, Poland, Romania
Terran Biosciences Australia Pty Ltd

Recruiting

A Study of Idazoxan in Healthy Participants

Healthy

Australia
Wayne State University

Completed

Effects of Buprenorphine/Naloxone Dose on Experimental Stress Reactivity and Opioid Abstinence (BOS)

Heroin Dependence | Opioid Use Disorder

United States
Daiichi Sankyo, Inc.

Completed

Study to Compare Welchol and TriCor to TriCor Alone in Patients With High Cholesterol

Hypercholesterolemia | Hyperlipidemia, Familial Combined

United States
Trevi Therapeutics

Completed

Study of Nalbuphine HCl ER Tablets in Patients With Prurigo Nodularis

Pruritus | Prurigo Nodularis | Prurigo | Nodularis Prurigo

United States, Germany, Poland
Mundipharma Research GmbH & Co KG

Completed

A Randomised Placebo Controlled Study of OXN PR for Severe Parkinson's Disease Associated Pain

Parkinson's Disease With Severe Pain

United Kingdom, Spain, Germany, Hungary, Czech Republic, Poland, Romania
Massachusetts General Hospital
Food and Drug Administration (FDA); Center for Psychiatry And Behavioral Medicine...

Completed

PK/PD Pediatric ADHD Classroom Study

Attention Deficit Hyperactivity Disorder

United States
Mundipharma Research GmbH & Co KG

Completed

A Study to Demonstrate the Analgesic Efficacy of Oxycodone/Naloxone Prolonged Release Tablets in Addition to Pregabalin Compared to Pregabalin Alone in Opioid-naïve Subjects Treated With Pregabalin Suffering From Moderate to Severe Pain Due to Diabetic Polyneuropathy

Moderate to Severe Pain Due to Diabetic Polyneuropathy

Germany
New York State Psychiatric Institute
Schering-Plough

Completed

Abuse Liability of Suboxone Versus Subutex

Opioid-related Disorders

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Fasting Conditions

Healthy

United States
Daiichi Sankyo, Inc.

Completed

Effects of Metformin Hydrochloride (HCl) in Combination With Colesevelam HCl, Compared to Metformin HCl Alone, in Patients With Type 2 Diabetes Mellitus and the Effects of Colesevelam HCl on Lipids and Glucose on Pre-diabetic Patients.

Type 2 Diabetes Mellitus | Hypercholesterolemia | Pre-diabetes

United States, Colombia, India, Mexico

3

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