Search clinical trials for: Narcotic Antagonists

Total 43172 results

Teva Pharmaceuticals USA

Withdrawn

An Open-Label, Single-Center Study to Evaluate the Exposure-Response Relationship Between the Plasma Drug Concentrations and the Change From Baseline in QTc at Steady State Following Once-daily Administration of CASSIPA® in Opioid Dependent Subjects.

Evaluation of QTc Interval
Yale University
National Institute on Drug Abuse (NIDA)

Completed

HIV Risk Reduction and Drug Abuse Treatment in Malaysia

Opiate Dependence

United States, Malaysia
Mundipharma (China) Pharmaceutical Co. Ltd

Unknown

A Study to Evaluate Buprenorphine Transdermal Patch in Chinese Subjects With Moderate to Severe Chronic Cancer Pain

Cancer Pain

China
NanoSHIFT LLC

Completed

A Single-Dose Study of an Investigational Capsule Formulation of 2 mg/0.5 mg Buprenorphine/Naloxone

Healthy

United States
University of California, Los Angeles

Completed

Buprenorphine/Naloxone Versus Clonidine for Inpatient Opiate Detoxification - 1

Heroin Dependence | Substance Withdrawal Syndrome | Morphine Dependence

United States
Mundipharma Korea Ltd

Completed

A Study to Assess the Efficacy and Safety of Oxycodone/Naloxone in Korean Patients With Chemotherapy-Induced Peripheral Neuropathy (CIPN)

Cancer

Korea, Republic of
Pain Therapeutics

Completed

Study to Evaluate the Subjective Effects of PTI-801 in Non-Physically Dependent Subjects With a History of Drug Abuse

Opioid-Related Disorders

United States
Mundipharma Pharmaceuticals B.V.

Completed

Oxycodone/Naloxone (OXN) Combination in Moderate to Severe Non-malignant Pain

Pain

Netherlands
IRCCS Policlinico S. Matteo

Withdrawn

Treatment of Chronic Pain From Osteoarthritis

Chronic Pain

Italy
National Institute of Allergy and Infectious Diseases...
National Institute on Drug Abuse (NIDA)

Terminated

Drug Treatment Combined With Drug and Risk Reduction Counseling to Prevent of HIV Infection and Death Among Injection Drug Users

HIV Infections | Opioid-Related Disorders

China, Thailand
University of Chicago

Completed

The Effects of Buprenorphine on Responses to Verbal Tasks

Basic Science

United States
New York State Psychiatric Institute

Completed

Prescription Opioid Abuse Among Pain Patients: Predictors of Relapse (PAIN)

Opioid Dependence

United States
Titan Pharmaceuticals
National Institute on Drug Abuse (NIDA)

Completed

A Six-Month Randomized Controlled Trial (RCT) of Probuphine Safety and Efficacy in Opioid Addiction

Opioid Dependency

United States
Mundipharma Research GmbH & Co KG

Completed

A Randomised, Double Blind, Placebo and Active Controlled, Double Dummy,Parallel Group Study to Determine the Safety and Efficacy of Oxycodone/Naloxone Prolonged Release Tablets in Subjects With Moderate to Severe, Chronic Nonmalignant Pain

Subjects With Moderate to Severe, Chronic Nonmalignant Pain
Thomas Jefferson University
National Institute on Drug Abuse (NIDA)

Completed

Buprenorphine for the Treatment of Neonatal Abstinence Syndrome

Neonatal Abstinence Syndrome

United States
Kaiser Permanente
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Completed

PRimary Care Opioid Use Disorders Treatment (PROUD) Trial (PROUD)

Opioid-use Disorder

United States
April M Young
National Institute on Drug Abuse (NIDA); Emory University; Centers for Disease... and other collaborators

Completed

Kentucky Communities and Researchers Engaging to Halt the Opioid Epidemic (CARE2HOPE)

HIV Infections | Substance Use | Opioid Use | HCV Infection | Sexually Transmitted Infections (Not HIV or Hepatitis) | Overdose, Drug

United States
University of Southern California
National Institute on Aging (NIA)

Completed

Encouraging Judicious Prescribing of Opioids in Los Angeles County

Substance-Related Disorders

United States
University of Washington
National Institute on Drug Abuse (NIDA); emocha Mobile Health, Inc.

Completed

Trial of Adherence App for Buprenorphine Treatment (TAAB) Study

Opioid-Related Disorders

United States
New York State Psychiatric Institute

Completed

Lorcaserin in Combination With XR-Naltrexone for Relapse Prevention in Opioid Use Disorder

Opioid-use Disorder

United States
Mundipharma (China) Pharmaceutical Co. Ltd

Completed

OXN PR Tablet 5/2.5 mg and20/10 mg PK Study in Chinese Moderate to Severe Chronic Non-malignant Patients

Chronic Pain

China
Butler Hospital

Completed

Linking Opioid Dependent Patients From Inpatient Detoxification to Primary Care

Illicit Opioid Drug Use

United States
Butler Hospital

Completed

Distress Tolerance and Buprenorphine (TRUST)

Opioid Dependence

United States
State University of New York - Upstate Medical...
University at Buffalo

Completed

Neuropsychoanalytic Treatment of Failed Back Surgery Syndrome-Opioid Dependence

Pain
Fox Chase Cancer Center

Recruiting

Buprenorphine for Cancer Pain

Cancer-Related Pain

United States
University of British Columbia

Recruiting

Evaluating Buprenorphine/Naloxone Microdosing vs. Standard Dosing in Emergency Departments

Opioid-use Disorder

Canada
NYU Langone Health
National Institute on Drug Abuse (NIDA)

Recruiting

Long-acting Buprenorphine vs. Naltrexone Opioid Treatments in CJS-involved Adults

Opioid-use Disorder

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Suspended

Extended-Release Buprenorphine vs. Sublingual Buprenorphine for the Treatment of Opioid Use Disorder

Opioid-use Disorder

United States
University of Alabama at Birmingham

Completed

Increasing Naloxone Access for Persons Who Use Opioids

Naloxone

United States
Indivior Inc.

Completed

Observational Study of Misuse of High Dose Buprenorphine (Subutex® or Generic) in Opiate-Addicted Patients in France (Study P05186AM1)(COMPLETED) (OPUS R)

Naloxone | Drug Abuse | Opiate Dependence | Buprenorphine | Opiate-related Disorders
Tongji Hospital

Unknown

The Analgesic Effect of Butorphanol After Cesarean Section

Analgesia
Indivior Inc.

Completed

Safety and Tolerability of Buprenorphine/Naloxone Film Strips

Opioid-Related Disorders

United States
State University of New York at Buffalo

Terminated

Buprenorphine as a Treatment in Opiate Dependent Pain Patients

Opiate Addiction | Refractory Pain

United States
VA Office of Research and Development

Recruiting

A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder (VA-BRAVE)

Opioid Use Disorder

United States
University of California, Irvine

Recruiting

Effect of Ultra-low Dose Naloxone on Remifentanil-Induced Hyperalgesia

Hyperalgesia

United States
Bibo Wang
Eastern Hepatobiliary Surgery Hospital

Completed

Butorphanol in Pain Following Ablation for Hepatic Tumor

Visceral Pain | Hepatic Tumor | Microwave Ablation

China
Butler Hospital

Completed

Neuroimaging Predictors of Relapse During Treatment for Opiate Dependence

Opioid Addiction

United States
Nassima Ait-Daoud Tiouririne

Unknown

Measures to Improve Outcomes After an Opioid Overdose

Opioid Overdose

United States
Pfizer

Completed

Healthy Volunteers Study to Estimate the Effects of Food on the Bioavailability of Oxycodone and Naltrexone/6- Β -Naltrexol From a Extended Release Formulation of Oxycodone With Sequestered Naltrexone

Healthy

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

RCT Comparing Methadone and Buprenorphine in Pregnant Women

Pregnancy | Opioid Dependence | Opioid Related Disorders

United States, Canada, Austria
Purdue Pharma LP

Completed

A Study of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain

Low Back Pain

United States
Mundipharma Research GmbH & Co KG

Completed

A Study to Demonstrate the Analgesic Efficacy of Oxycodone/Naloxone Prolonged Release Tablets in Addition to Pregabalin Compared to Pregabalin Alone in Opioid-naïve Subjects Treated With Pregabalin Suffering From Moderate to Severe Pain Due to Diabetic Polyneuropathy

Moderate to Severe Pain Due to Diabetic Polyneuropathy

Germany
Vertex Pharmaceuticals Incorporated
Tibotec BVBA

Completed

Drug-Drug Interaction Study Between Telaprevir and Buprenorphine

Hepatitis C | Opioid-Related Disorders

United States
Prisma Health-Upstate
National Institute on Drug Abuse (NIDA); Clemson University

Recruiting

An Integrated Intervention Involving Recovery Coaching and Cognitive Behavioral Therapy for Opioid Use Disorder (OVERCOME 2)

Standard of Care | Standard of Care + CBT4CBT | Standard of Care + CBT4CBT + RC

United States
Massachusetts General Hospital

Not yet recruiting

A Prospective, Randomized Trial of the Effect of Standard of Care Reduced Dose Versus Full Dose Buprenorphine/Naloxone in the Perioperative Period on Pain Control and Post-Operative Opioid Use Disorder Symptoms

Opioid-use Disorder | Opioid Use Disorder, Mild
Orexo AB
Worldwide Clinical Trials

Completed

Efficacy of BNX Sublingual Tablets Versus BNX Sublingual Film for Treatment of Opioid-Dependent Adults (ISTART)

Opioid Dependence, on Agonist Therapy

United States
University of Aarhus

Completed

Investigation of Analgesic and Anti-hyperalgesic Effect of Opioids in Experimental Pain

Pain

Denmark
University Hospital, Toulouse

Completed

On-site Evaluation of Substances Consumption on Opiate Maintenance (ESUB-MG)

Opiate Addiction

France
Indivior Inc.

Completed

An Observational Study of Environmental and SocioEconomic Factors in Opioid Recovery (RECOVER®)

Opioid-use Disorder | Opioid-related Disorders

United States
University of Wisconsin, Madison
AIDS Resource Center of Wisconsin

Completed

A Community-based, Behavioral Intervention to Improve Screening for Hepatitis C Among High-risk Young Adults in Wisconsin (Hep-Net)

Hepatitis C

3

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