Search clinical trials for: Nicotine (10 mg)

Total 13417 results

Taisho Pharmaceutical Co., Ltd.

Completed

Phase III Study of TS-142 in Patients With Insomnia

Patients With Insomnia

Japan
Shaheed Zulfiqar Ali Bhutto Medical University

Completed

Tocilizumab and Cytokine Release Syndrome (CRS) In Covid-19 Pneumonia

Cytokine Release Syndrome | Covid-19 Pneumonia

Pakistan
Cantex Pharmaceuticals

Recruiting

Azeliragon and Chemoradiotherapy in Newly Diagnosed Glioblastoma

Glioblastoma

Spain
MedImmune LLC

Completed

Phase 1 Single-ascending Dose Study to Evaluate Safety and Tolerability of MEDI4920 in Healthy Adults

Healthy Volunteer

United Kingdom
Caliway Biopharmaceuticals Co., Ltd.

Completed

A Study to Evaluate the Efficacy and Safety of CBL-514 in Participants With Dercum's Disease Lipomas

Dercum's Disease

United States
Bioprojet

Completed

Dose Range Finding Study of BF2.649 Versus Placebo to Treat Excessive Daytime Sleepiness in Parkinson's Disease Patients

Parkinson's Disease | Excessive Daytime Sleepiness

France
Pfizer

Completed

A Study To Observe Safety And Blood Concentrations Of PF-04995274 During And Following the Administration of Multiple Doses Of PF-04995274 In Healthy Adult And Healthy Elderly Volunteers.

Healthy

United States
Duke University
National Institute on Drug Abuse (NIDA)

Recruiting

Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for Smoking

Nicotine Dependence, Cigarettes | Adverse Childhood Experiences

United States
Centre for Addiction and Mental Health
Ontario Ministry of Health and Long Term Care

Completed

Phase I Study: Stop Smoking Therapy for Ontario Patients (STOP)

Smoking

Canada
Eisai Inc.

Completed

BLOOM-DM: Behavioral Modification and Lorcaserin for Overweight and Obesity Management in Diabetes Mellitus

Obesity

United States
University of Minnesota

Completed

Comparison Across Treatment Conditions to Reduce Smokeless Tobacco Use

Tobacco Use Disorder

United States
University of Nebraska
Institute for Science and Health

Completed

Validation of Biomarkers of Exposure and Host Response

Cigarette Smoker

United States
University of California, Los Angeles
Philip Morris USA, Inc.

Completed

Effects of Contingency Management and Nicotine Replacement Therapy on Youth Smoking

Cigarette Smoking Behavior

United States
Manal Abdelmalek

Completed

JKB-121 for the Treatment of Nonalcoholic Steatohepatitis

Nonalcoholic Steatohepatitis

United States
Merck Sharp & Dohme LLC

Completed

MK3207 for Treatment of Acute Migraines (3207-005)

Migraine
AmtixBio Co., Ltd.
Novotech (Australia) Pty Limited

Completed

A Study of ATB1651 in Adults With Mild to Moderate Onychomycosis

Onychomycosis

New Zealand
Janssen Research & Development, LLC

Completed

A Study to Assess the Effects of Age and Gender on the Pharmacokinetics of JNJ-42847922 in Healthy Adults

Healthy

United States
H. Lundbeck A/S

Terminated

Study Investigating Effects of Foliglurax in Patients With Parkinson's Disease (PD) and Healthy Subjects

Healthy | Parkinson Disease

France
Laboratorios Andromaco S.A.

Completed

Bioavailability of Diosmin/Hesperidin (90/10) 500 mg Tablets With Regards to Reference Product

Bioequivalence

India
Yokohama City University

Recruiting

Long-term Elobixibat for Chronic Constipation (TANK-27)

Chronic Constipation

Japan
Reata, a wholly owned subsidiary of Biogen

Completed

A Study of the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of RTA 901 in Healthy Adults

Healthy

United States
Naga P. Chalasani
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Intercept Pharmaceuticals

Terminated

Trial of Obeticholic Acid in Patients With Moderately Severe Alcoholic Hepatitis (AH) (TREAT)

Alcoholic Hepatitis

United States
Eisai Inc.

Completed

BLOOM: Behavioral Modification and Lorcaserin for Overweight and Obesity Management

Obesity

United States
Janssen Research & Development, LLC

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JNJ-54861911 in Healthy Elderly Participants

Healthy

Belgium
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Alendronate Sodium Tablets (10 mg) and Fosamax Tablets (10 mg)

Healthy

United States
University of Kansas Medical Center
Patient-Centered Outcomes Research Institute

Completed

Smoking Cessation Versus Long-term Nicotine Replacement Among High-risk Smokers

Smoking | Pulmonary Disease, Chronic Obstructive | Tobacco Use Disorder

United States
James BOYD MD
Michael J. Fox Foundation for Parkinson's Research; Philipps University Marburg... and other collaborators

Unknown

Disease-modifying Potential of Transdermal NICotine in Early Parkinson's Disease (NIC-PD)

Parkinson's Disease

United States, Germany
R.J. Reynolds Vapor Company
RAI Services Company; Davita Clinical Research

Completed

Assess Biomarkers of Tobacco Exposure and Nicotine Pharmacokinetics in Smokers After a 5-Day In-Clinic Confinement Switch to an Electronic Cigarette or Nicotine Gum

Smoking

United States
Vanderbilt University Medical Center

Completed

Nicotine Treatment of Cognitive Decline in Down Syndrome

Down Syndrome | Mild Cognitive Impairment

United States
UCB Pharma

Completed

Double-blind, Randomized Study Evaluating the Efficacy and Safety of Brivaracetam in Adults With Partial Onset Seizures

Epilepsy

United States, Australia, Canada, Brazil, Mexico
Vanderbilt University Medical Center
National Institute of Mental Health (NIMH); University of Florida

Terminated

Effects of Transdermal Nicotine on Response Inhibition to Emotional Cues in Schizophrenia

Schizophrenia | Impulsive Behavior

United States
Florida International University

Recruiting

Assessing the Effect of Nicotine Reduction on ENDS User's Addiction and Exposures

Electronic Cigarette Use

United States
University College, London

Completed

Effects of GABA Modulator AZD7325 on Cortical Excitability

Healthy

United Kingdom
The Netherlands Cancer Institute

Completed

Weekly Administration of (bi-)Daily Oral Docetaxel in Combination With Ritonavir

Cancer

Netherlands
Organon and Co

Completed

Ezetimibe (EZ)/Atorvastatin (Ator) (MK-0653C) vs. Ator in Chinese Hypercholesterolemic Participants (MK-0653C-439)

Hypercholesterolemia

China
McNeil AB

Completed

Multiple-dose Nicotine Pharmacokinetics With a New Oral Nicotine Replacement Product.

Tobacco Dependence

Sweden
Janssen Scientific Affairs, LLC

Completed

A Study to Evaluate the Efficacy and Safety of (D/C/F/TAF) Once Daily Fixed Dose Combination (FDC) Regimen in Newly Diagnosed, Antiretroviral Treatment-naive Human Immunodeficiency Virus Type 1 (HIV-1) Infected Participants Receiving Care in a Test and Treat Model of Care

HIV-1

United States
Viridian Therapeutics, Inc.

Not yet recruiting

A Randomized, Active Controlled, Safety and Tolerability Study of VRDN-001 in Participants With Thyroid Eye Disease (TED)

Thyroid Eye Disease

United States
Livzon Pharmaceutical Group Inc.

Completed

Ilaprazole for the Treatment of Duodenal Ulcer in Chinese Patients

Duodenal Ulcer
Ligand Pharmaceuticals

Completed

A Study of LGD-6972 in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Pfizer

Not yet recruiting

A Study to Learn About Zavegepant as a Treatment for Multiple Migraine Attacks in Adult Participants

Migraine
Takeda

Completed

TAK-114 Single- and Multiple-Dose Phase 1 Study

Clinical Pharmacology

Japan
Yale University

Recruiting

IV Pulsed-Nicotine as a Model of Smoking: The Effects of Dose and Delivery Rate

Nicotine Dependence

United States
Ionis Pharmaceuticals, Inc.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISIS 443139 in Participants With Early Manifest Huntington's Disease

Huntington's Disease

Canada, United Kingdom, Germany
Ablynx

Completed

Study Evaluating Multiple Ascending Doses Of ATN-103 In Japanese Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Japan
Bionov
Seppic

Completed

Multicentre, Double-blind Study Versus Placebo on Impact and Safety of Extramel® 140 IU on Perceived Stress, Physical and Intellectual Fatigue, Pain Perception if Present, and the Impact on the Quality of Life (Ex Stress II)

Quality of Life | Pain | Fatigue | Life Stress
Intercept Pharmaceuticals

Completed

Study Evaluating the Efficacy and Safety of Obeticholic Acid in Subjects With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (REVERSE)

Nonalcoholic Steatohepatitis | Compensated Cirrhosis

United States, Spain, France, Australia, New Zealand, Puerto Rico, Germany, Canada, United Kingdom, Hungary, Poland, Ukraine
CymaBay Therapeutics, Inc.

Recruiting

An Open-Label Study Following Oral Dosing of Seladelpar to Subjects With Primary Biliary Cholangitis (PBC) and Hepatic Impairment (HI)

Hepatic Impairment | Compensated Cirrhosis | Primary Biliary Cholangitis

Korea, Republic of, United States, Spain, United Kingdom
Eisai Co., Ltd.

Completed

A Study of APD356 (Lorcaserin) in Healthy Japanese Adult Subjects

Healthy Subjects

Japan
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Reduced Nicotine Cigarette Purchasing Decisions

Tobacco Use Disorder

United States

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