Search clinical trials for: nucleoside analogues

Total 398 results

NuCana plc

Completed

A Safety, Pharmacokinetic and Efficacy Study of NUC-3373 in Combination With Standard Agents Used in Colorectal Cancer Treatment

Colorectal Neoplasms | Colorectal Cancer | Colorectal Tumors | Colorectal Carcinoma | Neoplasms, Colorectal

United States, France, United Kingdom
Mitsubishi Tanabe Pharma Corporation

Completed

Long-Term Safety Study of Canagliflozin (TA-7284) in Combination With GLP-1 Analogue in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Japan
Medical University of Graz

Completed

Calcipotriol and Polymorphic Light Eruption

Polymorphic Light Eruption

Austria
University of Bologna
Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone

Not yet recruiting

Detection and Prevention of Cancer-Related Cardiovascular Toxicity Registry

Cancer Related Cardiovascular Toxicity

Italy, North Macedonia, Serbia
Bial - Portela C S.A.

Terminated

Eslicarbazepine Acetate as Therapy in Diabetic Neuropathic Pain

Painful Diabetic Neuropathy

Portugal
H. Lee Moffitt Cancer Center and Research Institute
Aprea Therapeutics

Completed

Phase 1b/2 Safety and Efficacy of APR-246 w/Azacitidine for tx of TP53 Mutant Myeloid Neoplasms

Acute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | Myeloproliferative Neoplasm

United States
Tehran University of Medical Sciences

Unknown

Assessment Vitamin D Analogues Intake Pathways on the Proteins Which Involved in Metabolic Rate in Obese Subjects

Obesity

Iran, Islamic Republic of
Seng Gee Lim
Singapore General Hospital; Tan Tock Seng Hospital; Changi General Hospital

Unknown

Halting Nucleoside Analogues in Chronic Hepatitis B (HALT-NUCS)

Chronic Hepatitis B

Singapore
Ain Shams Maternity Hospital
Dr. Ahmed S. Abd El-Hameed; Prof. Abdel-Megeeed I. Abdel- Megeeed

Completed

Nitroglycerin Skin Patches for Facilitating Cervical Ripening: A Randomized Controlled Trial

Induction of Labor Affected Fetus / Newborn

Egypt
Pusan National University Hospital

Unknown

HBsAg Decline After Pegylated-interferon-α in e Antigen Positive Chronic Hepatitis B With Nucleoside Maintenance

Chronic Hepatitis B

Korea, Republic of
Poznan University of Medical Sciences

Recruiting

Pericapsular Nerve Group Block Chemical Neurolysis in Advanced Hip Osteoarthritis (PENG)

Osteoarthritis | Osteoarthritis, Hip

Poland
Federal University of Rio Grande do Sul

Recruiting

PSLT Compared to Prostaglandin Analogue Eye Drops

Ocular Hypertension | Open Angle Glaucoma

Brazil
University of Copenhagen
Copenhagen University Hospital, Denmark

Completed

Interaction Between Immune Cells and Bacteria Associated With Periodontitis

Inflammation | Rheumatoid Arthritis | Periodontitis | Periodontal Diseases | Dysbiosis | Aggressive Periodontitis | Chronic Periodontitis | Periodontal Pocket | Generalized Chronic Periodontitis | Microbial Disease | Inflammation Gum | Immunologic Disease | Generalized Aggressive Periodontitis

Denmark
GlaxoSmithKline

Completed

Study To Evaluate Long Term Maintenance With TRIZIVIR After Boosted Protease Inhibitor (PI) Or Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) In HIV-1 Infected Adults

HIV Infections
Pär Johansson

Completed

Endothelial Dysfunction in Resuscitated Cardiac Arrest (ENDO-RCA)

Cardiac Arrest

Denmark
Groupe Francophone des Myelodysplasies
Aprea Therapeutics

Unknown

Study of the Safety and Efficacy of APR-246 in Combination With Azacitidine

Chronic Myelomonocytic Leukemia | Myeloproliferative Neoplasm | Acute Myeloid Leukemia With Gene Mutations | Myelodysplastic Syndrome With Gene Mutation

France
Kirby Institute

Active, not recruiting

Body Composition Sub-study of the D2EFT Trial

HIV Infections

Malaysia, Zimbabwe, India, South Africa, Thailand
xjpfW
Cancer Institute and Hospital, Chinese Academy of Medical Sciences; First Hospital... and other collaborators

Completed

Efficacy and Safety of Total Glucosides of Paeony Combined With NB-UVB on Treating Vitiligo

Vitiligo

China
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID); Merck Sharp... and other collaborators

Completed

A5288/MULTI-OCTAVE: Management Using Latest Technologies to Optimize Combination Therapy After Viral Failure (MULTI-OCTAVE)

HIV-1 Infection

Kenya, Brazil, South Africa, Uganda, Zimbabwe, India, Malawi, Haiti, Thailand, Peru
Zealand Pharma

Completed

Single Doses of ZP4207 Adm. sc to Hypoglycemic TD1 pt. to Describe the PK and PD of ZP4207 as Comp. to Marketed Glucagon

Hypoglycemia

Germany
Endo Pharmaceuticals

Terminated

Efficacy and Safety Study of Octreotide Implant in Patients With Acromegaly

Acromegaly

United States, Czech Republic, Germany, Hungary, Poland, Russian Federation, Serbia, Slovakia, Spain
Athenex, Inc.

Completed

Safety, Tolerability & PK of KX2-361 in Subjects w Adv. Malignancies Refractory to Conventional Therapies

Advance Malignancies

United States
Central Institute of Mental Health, Mannheim

Completed

Processing of Salient Emotional Stimuli as a Function of Tetrahydrocannabinol (THC) and Cannabidiol (CBD) (AB_THC_CBD)

Healthy Humans

Germany
Ohio State University

Recruiting

Strategies to Augment Ketosis: Optimization of Ketone Delivery Strategies (STAK: OK'd)

Ketosis

United States
University Hospital Tuebingen

Unknown

Observational Study of Analgesia and Cost-efficiency of Analgetic Medication Pumps (Zalviso and PCA-syringe Pump (PCA=Patient Controlled Analgesia)) After Urogenital Intervention at the Clinical Daily Routine

Mobility | Analgesic Quality

Germany
Assiut University

Unknown

Impact of Gonadotrophin Releasing Hormone Analogues on Oocyte and Embryo Quality

Infertility, Female
First Affiliated Hospital, Sun Yat-Sen University

Unknown

Impact of Blood Glucose at the First Trimester of Pregnant Women With Gestational Diabetes on Maternal and Fetal Outcomes and Metabolic Disorders: a Multi-central Prospective Cohort Study

Gestational Diabetes

China
Novartis Pharmaceuticals

Completed

A 6-month, Randomized, Open-label, Patient OutComes, Safety and Tolerability Study of Fingolimod (FTY720) 0.5 mg/Day vs. Comparator in Patients With Relapsing Forms of Multiple Sclerosis (EPOC)

Relapsing Forms of Multiple Sclerosis

United States, Canada, Puerto Rico
University of California, San Francisco
Forest Laboratories

Completed

A 52 Week Open Label Trial of Memantine for Frontotemporal Lobar Degeneration

Frontotemporal Lobar Degeneration
Dermaliq Therapeutics, Inc.

Completed

Safety and Efficacy Study of Topical DLQ01 in the Treatment of Androgenetic Alopecia (AGA) in Men

Androgenetic Alopecia

Australia
German Breast Group
Pfizer

Completed

Tamoxifen +/- GnRH Analogue vs Aromatase Inhibitor + GnRH Analogue in Male Breast Cancer Patients (MALE)

Male Breast Cancer

Germany
Nantes University Hospital

Completed

Efficacy and Tolerability of Memantine in Frontotemporal Dementia (FTD) Patients

Dementia

France
Société des Produits Nestlé (SPN)

Active, not recruiting

Effect of Oral NAD+ Precursors Administration on Blood NAD+ Concentration in Healthy Adults (NICO)

Healthy

Switzerland
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy of a Switch to Doravirine, Tenofovir, Lamivudine (MK-1439A) in Human Immunodeficiency Virus (HIV-1)-Infected Participants Virologically Suppressed on an Anti-retroviral Regimen in Combination With Two Nucleoside Reverse Transcriptase Inhibitors (MK-1439A-024) (DRIVE-SHIFT)

HIV-1 Infection
Second Affiliated Hospital, School of Medicine,...
The First Affiliated Hospital of Anhui Medical University; Peking Union Medical... and other collaborators

Recruiting

A Study of Efficacy and Safety of Idebenone vs. Placebo in Prodromal Parkinson Disease (SEASEiPPD)

Parkinson Disease | REM Sleep Behavior Disorder

China
Xiangya Hospital of Central South University

Recruiting

Efficacy and Safety Of Different Regimens In Patients With Type 2 Diabetes Receiving Intensive Insulin Therapy

Type 2 Diabetes Mellitus

China
Mclean Hospital
Forest Laboratories

Completed

An Open-Label Trial of Memantine in the Treatment of Binge Eating Disorder

Binge Eating Disorder

United States
Kenya Medical Research Institute
Dafra Pharma

Completed

A Randomised Trial of Artesunate-sulfamethoxypyrazine/Pyrimethamine Versus Praziquantel for the Treatment of S. Mansoni

Schistosoma Mansoni

Kenya
Eskisehir Osmangazi University

Completed

Pain and Anxiety Levels of Sleeperone Electronic Anesthesia System in Pediatric Patients

Pain | Dental Anxiety

Turkey
King Faisal Specialist Hospital & Research Center

Unknown

The Combination of GnRh Analogue and Aromatase Inhibitor in Receptor Positive Premenopausal Women With Advanced Breast Cancer

Advanced Breast Cancer

Saudi Arabia
Sciwind Biosciences APAC CO Pty. Ltd.
Hangzhou Sciwind Biosciences Co., Ltd.

Completed

Effects of XW003 Versus Liraglutide on Body Weight of Adult Participants With Obesity

Obesity

Australia
Olympion Medical Center
University of Ulm; University of Eastern Finland; University of Ioannina

Unknown

Disulfiram/Copper Combination In The Treatment of Newly Diagnosed Glioblastoma Multiform (GLIODIS)

Glioblastoma Multiforme

Greece
Sciwind Biosciences APAC CO Pty. Ltd.
Hangzhou Sciwind Biosciences Co., Ltd.

Completed

To Evaluate the Safety, Tolerability, PK, and PD of XW003 Injection in Healthy Adult Participants (XW003)

Obesity | Type 2 Diabetes Mellitus | Nonalcoholic Steatohepatitis

Australia
Eric Lenze
National Institute of Mental Health (NIMH)

Completed

Memantine Treatment for Improving Rehabilitation Outcomes and Preventing Depression in Older Adults

Depression

United States
Prof. Dr. Cemil Tascıoglu Education and Research...

Completed

Effect of Low Flow Anesthetics on Neurocognitive Decline in the Elderly

Neurocognitive Disorders | Inhalation; Vapor

Turkey
University of Nottingham

Unknown

Systemic Hormones and Muscle Protein Synthesis

Sarcopenia | Muscle Atrophy | Muscle Hypotrophy

United Kingdom
University of California, Davis
Forest Laboratories

Withdrawn

Efficacy and Safety of the Use of Memantine for Preserving Cognition in Adult Patients With Epilepsy (Forest)

Epilepsy

United States
University of Maryland, Baltimore
Food and Drug Administration (FDA)

Completed

Cimetidine Biowaivers

Healthy

United States
Second Affiliated Hospital, School of Medicine,...
Zhejiang Provincial Hospital of TCM; Guiyang Hospital of Stomatology

Recruiting

Head Yuanshi Dian Therapy in Burning Mouth Syndrome

Burning Mouth Syndrome | Oral Mucosa Disease

China
Johns Hopkins Bloomberg School of Public Health
University of California, Davis; Newcastle University; HarvestPlus

Completed

Efficacy of Biofortified Maize to Improve Maternal and Infant Vitamin A Status

Vitamin A Deficiency

Zambia

Search clinical trials for: nucleoside analogues

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