Search clinical trials for: OR-101 (Multiple ascending dose)

Total 758 results

Adare Pharmaceuticals, Inc.

Completed

Efficacy, Safety, and Pharmacokinetics of APT-1011 in Subjects With Eosinophilic Esophagitis (EoE) (FLUTE)

Eosinophilic Esophagitis

Spain, United States, Belgium, Switzerland, Germany, Canada
Eli Lilly and Company
CoLucid Pharmaceuticals

Completed

Lasmiditan Compared to Placebo in the Acute Treatment of Migraine: (SAMURAI)

Acute Migraine

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Terminated

Study Evaluating of Calcineurin Inhibitor and Sirolimus (Rapamune) Treatment in Liver Transplant Recipients

Liver Transplantation

Italy, Belgium, Spain, France, Canada, Germany, United States, United Kingdom, Portugal, Czech Republic, Switzerland, Netherlands
Whanin Pharmaceutical Company

Completed

Bioequivalence Study in Patients With Schizophrenia by Using Clozaril 100 mg Tablet (Clozapine) and WID-CLZ18

Schizophrenia

Korea, Republic of
Poznan University of Medical Sciences

Recruiting

Perineural Dexamethasone in Supraclavicular Brachial Plexus Block for Anesthesia After Pediatric Hand/Wrist Surgery

Wrist Injuries | Hand Injuries | Hand Injuries and Disorders | Hand Disease | Wrist Disease

Poland
Poznan University of Medical Sciences

Recruiting

Dexamethasone in Supraclavicular Brachial Plexus Block for Anesthesia After Pediatric Hand/Wrist Surgery

Hand Injuries and Disorders | Wrist Disease

Poland
Poznan University of Medical Sciences

Completed

Perineural Dexamethasone on the Duration of Popliteal Nerve Block for Anesthesia After Pediatric Ankle Surgery

Foot Diseases | Ankle Injuries | Ankle Disease | Foot Injury

Poland
Parameswaran Hari

Completed

Study of Bendamustine and IXAZOMIB (MLN9708) Plus Dexamethasone in Relapsed/Refractory Multiple Myeloma

Multiple Myeloma

United States
Craig Hospital
Allergan; The Craig H. Neilsen Foundation

Completed

Investigating Botulinum Toxin A to Treat Acute Neck/Upper Shoulder Pain Following a New Spinal Cord Injury.

Pain | Spinal Cord Injury

United States
Novartis Pharmaceuticals

Completed

Treatment of Canadian Men and Pre/Peri/Post-menopausal Women With ER+ Advanced Breast Cancer in the Real-World Setting With Hormone Therapy ± Targeted Therapy (Treat ER+ight)

HR+ HER2- Men, Pre/Postmenopausal Advanced Breast Cancer

Canada
Melissa K Accordino
Novartis Pharmaceuticals

Active, not recruiting

Study of Efficacy of Ribociclib After Progression on CDK4/6 Inhibition in Patients With HR+ HER2- Advanced Breast Cancer (MAINTAIN)

Metastatic Breast Cancer | Breast Carcinoma

United States
Assiut University

Completed

Detection of Bloodstream Pathogens in Hematological Malignancies

Bloodstream Infection

Egypt
IBSA Institut Biochimique SA

Recruiting

A New Sildenafil Oral Film in Patients With Erectile Dysfunction

Erectile Dysfunction

United States
Isfahan University of Medical Sciences
Mashhad University of Medical Sciences

Completed

Effect of Topical Dexamethasone on Histologic Response of Human Dental Pulp

Vital Pulp Therapy
Poznan University of Medical Sciences

Completed

Effect of Systematic Dexamethasone on the Duration of Popliteal Nerve Block for Anesthesia After Pediatric Ankle Surgery

Cerebral Palsy | Foot Diseases | Foot Deformities | Ankle Disease

Poland
Yu-Li Hospital
National Health Research Institutes, Taiwan; Department of Health, Executive...

Completed

The Pharmacogenetic Study , Readiness to Change, and Pharmacological Intervention for Smoking Cessation in Schizophrenia (PSIAARP)

Schizophrenia | Tobacco Dependence

Taiwan
Neutec Ar-Ge San ve Tic A.Ş

Withdrawn

Acute Bronchodilator Effects of Ipratropium/Levosalbutamol 20/50 mcg Fixed Dose Combination vs Salbutamol 100 mcg Inhaler Plus Ipratropium 20 mcg Inhalation Aerosol Free Combination in Patients With Stable COPD

Chronic Obstructive Pulmonary Disease
CymaBay Therapeutics, Inc.

Terminated

Study to Evaluate the Effects of Two Doses of MBX-8025 in Subjects With Primary Biliary Cirrhosis (PBC)

Primary Biliary Cirrhosis (PBC)

Germany, United States, Canada, United Kingdom, Poland
University of Florida
Gateway for Cancer Research; Cellworks Group Inc.

Withdrawn

iCare 2: Personalized Genomic Mutation Informed Treatment of Patients With Myelodysplastic Syndromes

Myelodysplastic Syndromes

United States
Merck Sharp & Dohme LLC
Eisai Inc.

Active, not recruiting

Efficacy and Safety of Lenvatinib (E7080/MK-7902) Plus Pembrolizumab (MK-3475) Plus Chemotherapy in Participants With Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-7902-015/E7080-G000-321/LEAP-015) (LEAP-015)

Advanced/Metastatic Gastroesophageal Adenocarcinoma

China, Japan, Poland, Hong Kong, Korea, Republic of, Canada, United States, Argentina, Australia, Belgium, Chile, Colombia, Costa Rica, France, Germany, Guatemala, Ireland, Israel, Italy, Russian Federation, Spain, Taiwan, Turkey, United...
Karolinska University Hospital
Muhimbili University of Health and Allied Sciences

Completed

Treatment of Uncomplicated Childhood Malaria in Tanzania by Artemether+Lumefantrine - Efficacy and Genotyping

Malaria

Tanzania
Postgraduate Institute of Medical Education and...

Unknown

Impact of Obesity on the Efficacy of Endocrine Therapy With Aromatase Inhibitors

Breast Cancer

India
Tonix Pharmaceuticals, Inc.

Withdrawn

Safety and Efficacy Study of TNX-102 SL in Participants With PTSD

PTSD

Kenya
Samsung Medical Center

Completed

Kidney Graft Function Under the Immunosuppression Strategies (MyLowCsA)

Chronic Renal Disease
Women's College Hospital

Completed

Analgesic Effect of Preoperative Dexamethasone in Gynecological Laparotomies - a Dose-ranging Study

Fatigue | Postoperative Pain | Postoperative Nausea and Vomiting

Canada
Chiesi Farmaceutici S.p.A.

Completed

Efficacy of Fixed Combination of Beclometasone + Formoterol + Glycopyrrolate Versus Foster® in COPD

Chronic Obstructive Pulmonary Disease

Hungary
Tonix Pharmaceuticals, Inc.

Completed

BEdtime Sublingual TNX-102 SL as Fibromyalgia Intervention Therapy (BESTFIT) (BESTFIT)

Primary Fibromyalgia

United States
Cairo University

Unknown

Dexamethasone With TAP Block Increasing the Duration of the Peripheral Nerve Block in Caesarian Section

Pain

Egypt
Peking University People's Hospital

Unknown

The Combination of High-dose Dexamethasone and Acetylcysteine as the Treatment of Newly-diagnosed ITP

Immune Thrombocytopenia

China
National Taiwan University Hospital

Completed

Efficacy of High-dose Dual Therapy vs Bismuth-containing Quadruple Therapy for Rescue Treatment of Hp Infection

Helicobacter Pylori Infection

Taiwan
Tonix Pharmaceuticals, Inc.

Completed

A Study To Evaluate The Efficacy And Safety Of TNX-102 SL In Patients With Fibromyalgia (RELIEF)

Fibromyalgia

United States
Rambam Health Care Campus

Unknown

Evaluation of Safety and Effectiveness of 2 Lower Dose Combined PDE5i's Versus Single Maximal Dose PDE5i Treatment (PDE5i)

Erectile Dysfunction

Israel
Actavis Inc.

Completed

A Relative Bioavailability Study of Bupropion Extended-Released 150 mg Tablets Under Fasting Conditions

Healthy

United States
Korea University Guro Hospital

Terminated

Antithrombotic Treatment in Patients With Effectively Maintained Sinus Rhythm After Atrial Fibrillation Ablation (ATEMS-AF)

Atrial Fibrillation

Korea, Republic of
Tonix Pharmaceuticals, Inc.

Completed

A Phase 3 Study To Evaluate The Efficacy And Safety Of TNX-102 SL In Patients With Fibromyalgia (RALLY)

Fibromyalgia

United States
Yale University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Diagnosing and Targeting Mechanisms of Diuretic Resistance in Heart Failure

Heart Failure

United States
Rajavithi Hospital

Completed

Neubotulinum Toxin Injection in Cerivical Dystonia (NTCD)

Cervical Dystonia

Thailand
Irish Research Radiation Oncology Group

Recruiting

Optimising Patient Experience in Head and Neck Radiotherapy (OPEN)

Head and Neck Cancer

Ireland
Tonix Pharmaceuticals, Inc.
Premier Research Group plc

Terminated

Safety and Efficacy Study of TNX-102 SL in Patients With Military-related PTSD (HONOR)

PTSD

United States
NEAT ID Foundation
ViiV Healthcare

Completed

An Open-Label, Multi-Centre, Randomised, Switch Study to Evaluate the Virological Efficacy Over 96 Weeks Of 2-Drug Therapy With DTG/RPV FDC in Antiretroviral Treatment-Experienced HIV-1 Infected Subjects Virologically Suppressed With NNRTIs Resistance Mutation K103N (WISARD)

HIV-1-infection

Spain, Belgium, France, Germany, Italy, United Kingdom
Tonix Pharmaceuticals, Inc.

Terminated

Repeat of: A Study to Evaluate Efficacy and Safety of Sublingual TNX-102 SL Tablet Taken at Bedtime in Patients With Fibromyalgia (RE-AFFIRM)

Nervous System Diseases | Musculoskeletal Diseases | Rheumatic Diseases | Muscular Diseases | Neuromuscular Diseases | Fibromyalgia | Myofascial Pain Syndromes

United States
Tonix Pharmaceuticals, Inc.

Completed

A Study to Evaluate eFFIcacy and Safety of Sublingual TNX-102 SL Tablet Taken at Bedtime in Patients With fibRoMyalgia (AFFIRM)

Nervous System Diseases | Musculoskeletal Diseases | Rheumatic Diseases | Muscular Diseases | Neuromuscular Diseases | Fibromyalgia | Myofascial Pain Syndromes

United States
Federal State Budgetary Institution, V. A. Almazov...

Recruiting

Prospective, Post-registration, Interventional, Randomized, in Parallel Groups, Multicenter Eurasian Clinical Study of DERIVO®/DERIVO® Mini Aneurysm Embolization Device, Europe-Asia

Intracranial Aneurysm

Russian Federation
Intech Biopharm Ltd.

Recruiting

Pharmacodynamic Equivalence of the Test and Reference Metered Dose Inhalers (MDIs) Containing Albuterol Sulfate in Adult Patients With Stable Mild Asthma

Mild Asthma

Taiwan, India
Memorial Sloan Kettering Cancer Center

Completed

Controlled Trial Comparing Nomogram-based Versus Standard Allocation of Acute Normovolemic Hemodilution (ANH) During Hepatic Resection

Liver Cancer

United States
GlaxoSmithKline

Completed

A Phase III Parallel Group Study, Comparing the Efficacy, Safety and Tolerability of the Fixed Dose Combination (FDC) of Fluticasone Furoate+Umeclidinium Bromide+Vilanterol (FF/UMEC/VI) With the FDC of FF/VI in Subjects With Inadequately Controlled Asthma

Asthma

Australia, United States, Argentina, Canada, Germany, Japan, Korea, Republic of, Romania, Russian Federation, Spain, South Africa, Netherlands, Poland, Italy, United Kingdom
Rafa Laboratories
Teva Branded Pharmaceutical Products R&D, Inc.

Terminated

Comparison of Delta-8-THC to Ondansetron in the Prevention of Acute Nausea From Moderately Emetogenic Chemotherapy

Cancer

Israel
Centre Hospitalier Departemental Vendee

Recruiting

Maintaining or Stopping Immunosuppressive Therapy in Patients With ANCA Vasculitis and End-stage Renal Disease (MASTER-ANCA)

End Stage Renal Disease | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

France
Biocad

Unknown

Efficacy and Safety of BCD-100 (Anti-PD-1) in Combination With Platinum-Based Chemotherapy and Bevacizumab in Patients With Recurrent, Persistent or Metastatic Cervical Cancer (CAESURA)

Cervical Cancer | Cervical Cancer Recurrent | Cervical Cancer Metastatic

Russian Federation
GWT-TUD GmbH

Completed

ASTRAL- a Clinical Study to Assess the Efficacy and Toxicity of High-dose Chemotherapy

Lymphoma, B-Cell | Lymphoma, T-Cell | Aggressive Non-hodgkin Lymphoma (aNHL)

Germany

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