Search clinical trials for: OR-101 (Multiple ascending dose)

Total 759 results

Karolinska Institutet

Completed

Dosing of Thromboprophylaxis and Mortality in Critically Ill COVID-19 Patients

Covid19 | Thromboembolism

Sweden
AstraZeneca

Completed

Two-part Safety, Tolerability, Pharmacodynamic and -Kinetic Study of Inhaled AZD8871 in Asthmatic and COPD Subjects

Asthma (Part 1) | COPD (Part 2)

United Kingdom
Haiphong University of Medicine and Pharmacy

Completed

Comparison of Efficacy of Two Combination Regimens for the Neisseria Gonorrhoeae and Chlamydia Coinfection

Chlamydia Trachomatis Infection | Neisseria Gonorrhoeae Infection

Vietnam
Ferring Pharmaceuticals

Completed

LutrePulse Hypogonadotropic Hypogonadism

Primary Amenorrhea With Hypogonadotropic Hypogonadism

United States, Canada
Brigham and Women's Hospital
Beth Israel Deaconess Medical Center; Johns Hopkins Bloomberg School of Public... and other collaborators

Withdrawn

Enhancing Nutrition and Antenatal Infection Treatment for Maternal and Child Health in Ethiopia (ENAT)

Sexually Transmitted Diseases | Preterm Birth | Urinary Tract Infections | Low Birthweight | Maternal; Malnutrition, Affecting Fetus | Pregnancy and Infectious Disease
Faculdade de Medicina do ABC

Unknown

Phase II Clinical Trial of Uncaria Tomentosa (Cat´s Claw) in Patients With Advanced Solid Tumors (cat´sclaw)

Solid Tumors

Brazil
National Cancer Center, Korea

Unknown

Decision Aids for Tamoxifen Treatment in Breast Cancer Patients

Breast Cancer
AstraZeneca
Quintiles, Inc.

Completed

Absorption, Metabolism, Excretion and Pharmacokinetics of a Single Dose [14C]AZD2014 Followed by a Multiple Dose Phase (14C)

Solid Malignancies

United Kingdom
EpicentRx, Inc.

Completed

A Phase 2 Randomized, Open-Label Study of RRx-001 vs Regorafenib in Subjects With Metastatic Colorectal Cancer (ROCKET)

Colorectal Neoplasms

United States
Memorial Sloan Kettering Cancer Center
Ascenta Therapeutics

Terminated

Erlotinib and AT-101 in Advanced Non-Small Cell Lung Cancer (NSCLC) Patients With Epidermal Growth Factor Receptor (EGFR) Activating Mutations

Lung Cancer

United States
ANRS, Emerging Infectious Diseases

Completed

Pilot Study to Assess Efficacy and Safety of Sofosbuvir/Ledipasvir Fixed-dose Combination in Treatment Experienced Subjects With Hepatitis C Virus (HCV) Genotype 1 - HIV Co-infection

HIV | Viral Hepatitis C

France
Raymond T. Chung, MD
Merck Sharp & Dohme LLC

Withdrawn

Preemptive Zepatier Treatment in Donor HCV Positive to Recipient HCV Negative Cardiac Transplant

Hepatitis C | Cardiac Transplant Disorder

United States
Goethe University

Active, not recruiting

Capecitabine-based Chemoradiotherapy in Combination With the IL-1 Receptor Antagonist Anakinra for Rectal Cancer Patients (ACO/ARO/AIO-21)

Rectal Cancer

Germany
First Affiliated Hospital, Sun Yat-Sen University
Second Affiliated Hospital of Guangzhou Medical University

Unknown

Effect of BM-MSCs in DCD Kidney Transplantation

Kidney Transplantation | Acute Kidney Tubular Necrosis

China
Alan Barkun
Pendopharm

Completed

The Bowel CLEAnsing: A National Initiative (B-CLEAN)

Subjets Requiring a Colonoscopy

Canada
Memorial Sloan Kettering Cancer Center
GlaxoSmithKline

Completed

Sequential Chemo-Radioimmunotherapy Followed by Autologous Transplantation for Patients With Untreated Advanced Stage Mantle Cell Lymphoma

Mantle Cell Lymphoma

United States
Lykos Therapeutics

Completed

Dose-Response Study of MDMA-assisted Psychotherapy in People With PTSD

Posttraumatic Stress Disorder

United States
Shenox Pharmaceuticals, LLC

Unknown

Ketamine for Major Depressive Disorder

Major Depressive Disorder

United States
Assistance Publique - Hôpitaux de Paris
Aventis Pharmaceuticals

Completed

Celiprolol in Patients With Ehlers-Danlos Syndrome, Vascular Type

EHLERS-DANLOS SYNDROME, TYPE IV, AUTOSOMAL DOMINANT | CHROMOSOME 2q31.2 DELETION SYNDROME
Arkansas Children's Hospital Research Institute

Completed

Preservation of Pancreatic Beta Cell Function Through Insulin Pump Therapy (ktpump)

Diabetes Mellitus

United States
University Hospital, Angers

Completed

Sildenafil Efficacy Study on Time Walk From Peripheral Arterial Desease Patients (Stade II) With Arterial Claudication (ARTERIOFIL)

Peripheral Arterial Occlusive Disease
University of Colorado, Denver
National Institute of Allergy and Infectious Diseases (NIAID); University of...

Completed

Effect of Gender and HIV Infection on Zidovudine and Lamivudine Pharmacokinetics

HIV

United States
S1 Biopharma, Inc.

Completed

Phase 1b/2a Unblinded Study of Responses in Premenopausal Women With HSDD to Lorexys Evaluating Efficacy and Safety (PURPLE)

Hypoactive Sexual Desire Disorder (DSM-IV-TR Defined) | Sexual Interest/Arousal Disorder (DSM-5 Defined)

United States
Hadassah Medical Organization

Terminated

TSO in Pediatric Autistic Spectrum Disorders (TSO)

Autistic Spectrum Disorders

Israel
Medical College of Wisconsin
Barbara Ann Karmanos Cancer Institute; Cornerstone Pharmaceuticals

Recruiting

CPI-613 (Devimistat) in Combination With Chemoradiation in Patients With Pancreatic Adenocarcinoma

Pancreas Adenocarcinoma

United States
Auzone Biological Technology Pty Ltd
TIGERMED AUSTRALIA PTY LIMITED; CMAX Clinical Research Pty Ltd

Completed

A Study of TTYP01 in Healthy Adult Subjects

Healthy Adult Subjects

Australia
University of Michigan
Food and Drug Administration (FDA)

Completed

Correlation of Mesalamine Pharmacokinetics With Local Availability

Local Drug Concentration in Gastrointestinal Tract

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (Explores What the Body Does to the Drug), and Pharmacodynamics (Explores What a Drug Does to the Body) of JNJ-38431055 in Volunteers With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
AstraZeneca

Completed

A Study to Assess the Bioavailability and to Compare the Pharmacokinetics of AZD7594 Inhaled Via Monodose Inhaler and Multiple-dose Dry Powder Inhalers (DPI) or Pressurized Metered-dose Inhaler (pMDI) in Healthy Male Subjects

Asthma | Chronic Obstructive Pulmonary Disease (COPD)

United States
HeNan Sincere Biotech Co., Ltd
Beijing YouAn Hospital; Beijing Ditan Hospital; Peking Union Medical College... and other collaborators

Completed

A Drug Safety and Dose-exploratory Clinical Study of Azvudine Tablets in Patients Who Have Not Received Anti-HIV Treatment (FNC)

AIDS

China
Danat Al Emarat Hospital

Not yet recruiting

Quadratus Lumborum Block After Cesarean Section: Analgesic Efficacy of Different Concentrations of Local Anesthetics

Outcome Measures
Northwestern University
National Cancer Institute (NCI); Merck Sharp & Dohme LLC; Astex Pharmaceuticals...

Completed

Guadecitabine and Pembrolizumab in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma

United States
Novartis Pharmaceuticals
European and Developing Countries Clinical Trials Partnership (EDCTP); Medicines... and other collaborators

Active, not recruiting

Pharmacokinetics, Safety, Tolerability and Efficacy of a New Artemether-lumefantrine Dispersible Tablet in Infants and Neonates <5 kg Body Weight With Acute Uncomplicated Plasmodium Falciparum Malaria (CALINA)

Plasmodium Falciparum Malaria

Burkina Faso, Congo, The Democratic Republic of the
Meir Medical Center

Completed

Anti-factor Xa Based Venous Thromboembolism Prophylaxis

Dose Adjustment of Enoxaparin in ICU Patients

Israel
Eisai Limited

Terminated

A Study to Evaluate the Safety and Tolerability and Explore the Efficacy of Zonisamide as add-on Therapy in Elderly Patients With Refractory Partial Seizures

Epilepsy

United Kingdom, Germany, Hungary, Switzerland, Italy, Netherlands, Poland
Centre de recherche du Centre hospitalier universitaire...

Recruiting

Impact in Older Adults of Reducing Anticholinergic and Sedative Rx Burden on Physical Function Measured by Wearables

Physical Function | Deprescribing Anticholinergic and Sedative Medications

Canada
Memorial Sloan Kettering Cancer Center
Bristol-Myers Squibb

Completed

Induction Therapy With Cytarabine, High-Dose Mitoxantrone and Dasatinib for Patients With Philadelphia-Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia

Leukemia | Acute Lymphoblastic Leukemia

United States
Chang Gung Memorial Hospital

Recruiting

Dose Escalation and Dose Expansion Study of GAS in Subjects With Metastatic Pancreatic Adenocarcinoma (GAS)

Metastatic Pancreatic Adenocarcinoma

Taiwan
Memorial Sloan Kettering Cancer Center
Tufts Medical Center; Lahey Clinic

Completed

Lenalidomide (Revlimid®) Plus Low-dose Dexamethasone (Ld x 4 Cycles) Then Stem Cell Collection Followed by Randomization to Continued Ld or Stem Cell Transplantation (SCT) Plus Maintenance L

Multiple Myeloma

United States
Biocad

Recruiting

Efficacy and Safety of BCD-100 (Anti-PD-1) in Combination With Platinum-Based Chemotherapy as First Line Treatment in Patients With Advanced Non-Squamous NSCLC (DOMAJOR)

Non-Squamous Non-Small Cell Neoplasm of Lung

Czechia, Romania, Georgia, Hungary, Russian Federation, Slovakia
Amgen

Completed

Double-Blind Randomized Crossover Trial to Access Electrocardiogram Effects of HPN-100

Drug Toxicity

United States
Millennium Pharmaceuticals, Inc.

Completed

A Study of PVP001, PVP002, and PVP003 in Healthy Adults and PVP001 and PVP002 in Adults With Celiac Disease

Digestive System Disease

United States
Emergo Therapeutics, Inc.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Norketotifen in Healthy Subjects

Healthy Subjects

United States
Georgetown University
University of Chicago; Thomas Jefferson University

Completed

Palbociclib / Letrozole or Fulvestrant in African American Women With HR+ HER2- Breast Cancer (PALINA)

Hormone Receptor Positive HER-2 Negative Breast Cancer

United States
Harvard School of Public Health (HSPH)
Centre de Recherche en Sante de Nouna, Burkina Faso

Completed

School-Based Assessment of Micronutrient Interventions in Adolescents in Burkina Faso (SAMIA)

Anemia

Burkina Faso
The HIV Netherlands Australia Thailand Research...
Ministry of Education, Thailand

Completed

Efficacy and Safety of Single Versus Double Ritonavir-boosted Protease Inhibitor (PI)-Based Antiretroviral Therapy (ART) Regimens

HIV Infections | HIV Infection

Thailand
University of Michigan

Terminated

OPTIMA-TBI Pilot Study (OPTIMA)

Mild Traumatic Brain Injury

United States
Hospital Regional de Alta Especialidad del Bajio
Braulio Omar Manzo Pérez; Edson Dazaeb Flores Hernández; Pompeyo Stalin Alarcón...

Unknown

Holmium Vs Trilogy Kidney Stones GUY's 1-2 (TriHolmium)

Kidney Diseases | Kidney Calculi | Kidney Stone

Mexico
Dana-Farber Cancer Institute
Novartis

Terminated

Ribociclib + PDR001 in Breast Cancer and Ovarian Cancer

Metastatic Hormone-Receptor-Positive (HR+) Breast Cancer | HER2-Negative Breast Cancer | Metastatic Epithelial Ovarian Cancer

United States
Amsterdam UMC, location VUmc

Completed

High Dose Rate Brachytherapy for Treatment of Keloids

Keloid

Netherlands

Search clinical trials for: OR-101 (Multiple ascending dose)

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