Search clinical trials for: OSI-774

Total 1497 results

Ono Pharmaceutical Co. Ltd

Completed

ONO-7746 Study in Healthy Adult Subjects

Healthy Adult Subjects

United States
Link Medicine Corporation

Completed

A Double-Blind, Placebo Controlled, Single, Escalating Dose Study to Evaluate the Preliminary Pharmacokinetics, Safety and Tolerability of LNK-754 in Healthy Elderly Volunteers

Healthy Elderly Volunteers

United States
National Cancer Institute (NCI)
Eastern Cooperative Oncology Group; NCIC Clinical Trials Group; Southwest Oncology... and other collaborators

Terminated

Pemetrexed Disodium or Erlotinib Hydrochloride as Second-Line Therapy in Treating Patients With Advanced Non-small Cell Lung Cancer (MARVEL)

Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Recurrent Non-Small Cell Lung Carcinoma | Stage IV Non-Small Cell Lung Cancer

United States, Canada
National Cancer Institute (NCI)

Completed

Celecoxib and Erlotinib in Treating Former Smokers With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

Stage IIIB Non-small Cell Lung Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer

United States
National Cancer Institute (NCI)

Completed

Bevacizumab and Erlotinib Hydrochloride in Treating Patients With Metastatic or Unresectable Biliary Tumors

Gastrointestinal Cancer | Recurrent Extrahepatic Bile Duct Cancer | Recurrent Gallbladder Cancer | Unresectable Extrahepatic Bile Duct Cancer | Unresectable Gallbladder Cancer | Cholangiocarcinoma of the Extrahepatic Bile Duct | Cholangiocarcinoma of the Gallbladder

United States
University of Aarhus

Recruiting

Proton Cranio-spinal Irradiation for Leptomeningeal Metastasis (CSI ProLong)

Leptomeningeal Metastasis

Denmark
Università degli Studi di Sassari
Dr. Dario Melodia; Dr. Milena Pisano; Dr. Aurea Lumbau; Prof. Silvio Mario Meloni; Prof. Edoardo Baldoni

Not yet recruiting

RCT GBR One Stages Comparing A-Oss and Autogenous Bone Versus A-Oss and LCR-A

Dental Implant | Guided Bone Regeneration

Italy
University of Manitoba
St. Boniface Hospital; Arterial Stiffness Incorporated

Terminated

Assessment of Three Instruments for the Non-invasive Measurement of Arterial Stiffness. (ASI-2012)

Coronary Artery Disease | Healthy | Obesity | Peripheral Arterial Disease | Diabetes Type 2

Canada
Taipei Veterans General Hospital, Taiwan

Unknown

Impact of Sleep Apnea on Sepsis Mortality

Sleep Apnea Syndromes | Sepsis | Mortality

Taiwan
Amgen

Active, not recruiting

A Phase 1 Safety, Tolerability, and Pharmacokinetics Study of AMG 794 With Claudin 6-positive Non-small Cell Lung Cancer, Epithelial Ovarian Cancer, and Other Malignant Solid Tumor Indications

Non-squamous Non-small Cell Lung Cancer | Epithelial Ovarian Cancer | Claudin 6-positive Advanced/Metastatic Malignant Solid Tumors

United States, Australia, Switzerland
Ono Pharma USA Inc

Terminated

A Study of the Safety and Efficacy of ONO-7746 in Adult Cancer Patients With Chemotherapy Induced Thrombocytopenia

Chemotherapy-Induced Thrombocytopenia

United States, Korea, Republic of, Russian Federation
Ono Pharmaceutical Co. Ltd

Completed

ONO-7746 Study in Healthy Adult Subject

Healthy Adult Subjects

United States
OriCell Therapeutics Co., Ltd.

Recruiting

Ori-C101Chimeric Antigen Receptor (CAR) Modified T Cells for the Treatment of HCC

Hepatocellular Carcinoma

China
Kodiak Sciences Inc

Terminated

Exploratory Study to Investigate the Bioactivity, Ocular and Systemic Safety, Tolerability, and Pharmacokinetics Following Single and Multiple Intravitreal Administrations of KSI-301 in Subjects With wAMD, DME and RVO

Diabetic Macular Edema | Retinal Vein Occlusion | Wet Age-related Macular Degeneration

United States
Beth Israel Deaconess Medical Center
Dana-Farber Cancer Institute; Radiological Society of North America

Active, not recruiting

Comparing Restriction Spectrum Imaging (RSI) to Conventional and Abbreviated Breast MRI for Breast Cancer Screening

Breast Cancer

United States
Seoul National University Hospital

Completed

Oxygen Reserve Index in Airway Surgery in Children

Hypoxemia During Surgery

Korea, Republic of
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety and Pharmacokinetics of a Single Dose of GSI-953

Healthy

Japan
Taipei Veterans General Hospital, Taiwan

Unknown

Age and Sleep Apnea Syndrome

OSA | Age Problem

Taiwan
Suzhou Neuralstem Biopharmaceuticals

Unknown

Intracerebral Transplantation of Neural Stem Cells for the Treatment of Ischemic Stroke

Ischemic Motor Stroke, Chronic

China
Neelesh Sharma MD PhD

Completed

Erlotinib Hydrochloride and Quinacrine Dihydrochloride in Stage IIIB-IV Non-Small Cell Lung Cancer

Stage IIIB Non-small Cell Lung Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer

United States
National Cancer Institute (NCI)

Completed

Erlotinib and Celecoxib in Treating Patients With Stage IIIB or Stage IV Recurrent Non-Small Cell Lung Cancer

Stage IIIB Non-small Cell Lung Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer

United States
National Cancer Institute (NCI)

Completed

S0727 Gemcitabine Hydrochloride and Erlotinib Hydrochloride With or Without Monoclonal Antibody Therapy in Treating Patients With Metastatic Pancreatic Cancer That Cannot Be Removed By Surgery

Stage IV Pancreatic Cancer

United States
National Cancer Institute (NCI)

Completed

Bevacizumab and Erlotinib in Treating Patients With Advanced Liver Cancer

Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Adult Primary Hepatocellular Carcinoma

United States
Statens Serum Institut
Bill and Melinda Gates Foundation; Syneos Health; Larix A/S; AJ Vaccines A/S

Completed

Safety and Immunogenicity of Adjuvanted Reduced Dose Inactivated Polio Vaccine Given at 6, 10, 14 Weeks and 9 Months (VIPV-06)

Poliomyelitis

Philippines
Statens Serum Institut
Bill and Melinda Gates Foundation; Larix A/S; Vaxtrials S.A.; AJ Vaccines A/S

Completed

Safety and Immunogenicity of Adjuvanted Reduced Dose Inactivated Polio Vaccine in 2, 4, 6 Months of Age (VIPV-07)

Poliomyelitis

Panama
Vedic Lifesciences Pvt. Ltd.

Recruiting

A Study to Evaluate the Efficacy of EQ-778 on Upper Respiratory Tract Health Status in Healthy Adults

Upper Respiratory Tract Infection

India
Amgen

Completed

Study to Evaluate the Efficacy and Safety of AMG 714 in Adult Patients With Type II Refractory Celiac Disease

Type II Refractory Celiac Disease (RCD-II) | In-situ Small Bowel T-cell Lymphoma

Spain, United States, Finland, France, Netherlands
Amgen

Terminated

20101299: Study to Evaluate the Effect of AMG 747 on Schizophrenia Negative Symptoms

Schizophrenia

United States, Canada, Spain, Australia, New Zealand, Russian Federation, Singapore
Amgen

Terminated

20110165: Study to Evaluate the Effect of AMG 747 on Schizophrenia Negative Symptoms (Study 165)

Schizophrenia

United States, France, United Kingdom, Malaysia, Poland, Czech Republic
National Taiwan University Hospital

Recruiting

To Evaluate OBI-833/OBI-821 in Patients With Locally Advanced, Globo H-Positive Esophageal Cancer for Recurrence

Esophageal Cancer

Taiwan
Amgen

Available

AMG 714 Expanded Access Program

Celiac Disease
AbbVie

Terminated

A Study Evaluating the Safety and Pharmacokinetics of ABBV-744 in Participants With Relapsed/Refractory Acute Myeloid Leukemia (AML) Cancer

Acute Myeloid Leukemia (AML)

United States
Rambam Health Care Campus

Recruiting

The Use of Bio-Oss Collagen for Sinus Augmentation Using the Transcrestal Approach.

Bone Loss | Missing Teeth

Israel
Wake Forest University Health Sciences
Carolinas Fertility Institute (CFI); Wake Forest Institute for Regenerative... and other collaborators

Recruiting

Experimental Round Spermatid Injection (ROSI) to Treat Infertile Couples (ROSI)

Infertility, Male

United States
Sándor Beniczky
Hospital del Mar; Centro Hospitalar e Universitário de Coimbra, E.P.E.; Motol... and other collaborators

Active, not recruiting

Clinical Utility of Automated Electric Source Imaging in Presurgical Evaluation (PROMAESIS)

Surgery | Refractory Epilepsy | Electroencephalography | Brain Imaging

Spain, Portugal, Austria, Czechia, Denmark, Germany, Italy, Romania
BioNTech SE
Pfizer

Completed

To Evaluate the Safety, Tolerability, Efficacy and Immunogenicity of BNT162b2 Boosting Strategies Against COVID-19 in Participants ≥12 Years of Age.

COVID-19 | SARS-CoV-2 Infection

United States, Brazil, South Africa, Germany, Canada, Israel
Virginia Commonwealth University

Completed

Intervention Effectiveness on the Neurocognitive Functioning of Children and Adolescents With Neurofibromatosis Type 1 (OPTIMAL-SSI)

Neurofibromatosis 1 | Neurocognitive Deficit | Mental Health Impairment

United States
Biosion, Inc.
Southern Star Research Pty Ltd.

Completed

Safety and Tolerability of BSI-045B in Healthy Adult Subjects and Patients With Atopic Dermatitis

Atopic Dermatitis

Australia
Masimo Corporation

Completed

Correlation of Changes in PaO2 and ORi in Adult Patients

Hyperoxia

United States
Astes

Completed

Inter Scorers Agreement for OSA Screening Scores.

Sleep Apnea, Obstructive

Belgium
Qu Biologics Inc.

Completed

Exploratory Study of QBKPN SSI in Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

Canada
Astes

Withdrawn

Interest of the OSA (Obstructive Sleep Apnea) Predictive Scores in the Prognosis of Postoperative Mortality of Femoral Neck Fractures

Femoral Neck Fracture

Belgium
Assistance Publique Hopitaux De Marseille

Completed

Assessment of Fistula Closure by OTSC Clip After Bariatric Surgery

Bariatric Surgery (Sleeve Gastrectomy )

France
BioNTech SE
Pfizer

Completed

A Study to Learn About New COVID-19 RNA Vaccine Candidates in COVID-19 Vaccine-Experienced Healthy Individuals

COVID-19 | SARS-CoV-2 Infection

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

Study to Test AKR1C3-Activated Prodrug OBI-3424 (OBI-3424) in Patients With Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Refractory T Acute Lymphoblastic Leukemia | Recurrent T Acute Lymphoblastic Leukemia

United States
National Cancer Institute (NCI)

Completed

Bevacizumab and Erlotinib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous Cell Carcinoma of the Oropharynx | Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal... and other conditions

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI); OSI Pharmaceuticals

Completed

Docetaxel, Cisplatin, Pegfilgrastim, and Erlotinib Hydrochloride in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

Non-small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer | Squamous Cell Lung Cancer | Adenocarcinoma of the Lung | Bronchoalveolar Cell Lung Cancer | Large Cell Lung Cancer | Adenosquamous Cell Lung Cancer

United States
University Hospital, Angers

Completed

ORI2 : ORI for hyperOxia Reduction in ICU (ORI2)

Intensive Care Units

France
Academisch Medisch Centrum - Universiteit van Amsterdam...
DexCom, Inc.

Completed

Factors in Accuracy Studies Influencing Measured CGM Performance. (FACT-CGM)

Diabetes Mellitus, Type 1

Netherlands
JS InnoPharm, LLC

Recruiting

ERK Inhibitor JSI-1187 in Advanced Solid Tumors

Melanoma | NSCLC | Solid Tumor

China

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