Search clinical trials for: OTX-DP (Dexamethasone punctum plug)

Total 331 results

Ocular Therapeutix, Inc.

Completed

Phase II Study Evaluating Safety/Efficacy of OTX-DP for Treatment of Ocular Inflammation and Pain After Cataract Surgery

Ocular Inflammation and Pain

United States
Lahey Clinic

Completed

Lid Margin And Conjunctival Microbial Flora Following Punctum Occlusion

Dry Eye Syndrome

United States
Ocular Therapeutix, Inc.

Unknown

Non-Significant Risk Feasibility Study to Assess Retention and Replacement of the OTX Punctum Plug

Healthy Subjects
ReNeuron Limited

Completed

Safety Trial Of CTX Cells In Patients With Lower Limb Ischaemia

Peripheral Arterial Disease

United Kingdom
Ocular Therapeutix, Inc.

Completed

A Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Allergic Conjunctivitis

Allergic Conjunctivitis

United States
ReNeuron Limited

Completed

Pilot Investigation of Stem Cells in Stroke Phase II Efficacy (PISCES-II)

Cerebral Infarction | Hemiparesis | Ischaemic Stroke | Arm Paralysis

United Kingdom
Ocular Therapeutix, Inc.

Active, not recruiting

OTX-DED for the Short-term Treatment of the Symptoms of Dry Eye Disease (DED)

Eye Diseases | Dry Eye Syndromes

United States
Mati Therapeutics Inc.

Completed

An Open-Label, Multi-Center, Clinical Study Evaluating the Effect of the NDE L68 StableFit® Punctal Plug on the Tear Lake

Dry Eye Syndromes

United States
Allergan

Completed

Safety and Efficacy of Punctal Plug Insertion in Patients With Dry Eye

Dry Eye

Singapore
Johns Hopkins University

Terminated

Safety and Efficacy of Dexamethasone Ophthalmic Insert (Dextenza®) in the Management of Clinically Significant Dry Eye

Dry Eye

United States
Tanta University

Completed

Quality of Life Improvement in Dry Eye Patients After Intense Pulsed Light Therapy Compared to Punctal Plugs

Evaporative Dry Eye

Egypt
Ocular Therapeutix, Inc.

Completed

Phase 3 Study Evaluating Safety and Efficacy of OTX-DP for Treatment of Ocular Inflammation and Pain After Cataract Surgery

Post Ocular Surgical Inflammation and Pain

United States
University of New Mexico

Withdrawn

Punctal Plugs and Iodine Related Discomfort

Dry Eye Syndromes

United States
Ocular Therapeutix, Inc.

Completed

Multi-Arm Feasibility Study Evaluating OTX-TP Compared to Timolol in Treatment of Subjects With Open Angle Glaucoma

Glaucoma

South Africa
University of Oklahoma

Completed

The Effect of Punctal Plugs on Ocular Surface After Povidone-Iodine Preparation of Intravitreal Injection

Dry Eye | Dry Eye Syndromes | Ocular Surface Disease

United States
Shaare Zedek Medical Center

Unknown

Safety, Tolerability and Preliminary Efficacy of Unilateral Latanoprost-loaded Punctual Plug -EXP-LP (EXP-LP)

Ocular Hypertension | Glaucoma | IOP

Israel
Celgene
Stanford University

Terminated

VTX-2337 in Combination With Radiotherapy in Patients Low-Grade B-cell Lymphomas

Low Grade B Cell Lymphoma

United States
Benha University

Completed

Outcome of Omega 3 FA and Punctal Plugs on Ocular Surface Disease

Ocular Surface Disease

United Arab Emirates
Rabin Medical Center
Alpha Net Co. Ltd.

Completed

Perforated Punctal Plugs for Treatment of Papillary Conjunctivitis in Otherwise Healthy Patients

Conjunctivitis | Epiphora

Israel
Rabin Medical Center

Unknown

A Comparison Between Bandage Contact Lens, Punctal Plugs and Standard Measures in Preventing Corneal Injuries (COMLENPLSTAN)

Contact Lens and Punctal Plug in Preventing Corneal Injuries

Israel
Yonsei University

Completed

Effect of ADDE on Tear Interferometry

Dry Eye Syndromes | Tear

Korea, Republic of
Mati Therapeutics Inc.
QLT Inc.

Completed

A Study of the L-PPDS With Adjunctive Xalatan® Eye Drops in Subjects With OH or OAG

Ocular Hypertension | Open-Angle Glaucoma

United States
Mati Therapeutics Inc.

Completed

A Phase 2 Single-Masked, Randomized Study of Latanoprost PPDS in Ocular Hypertension or Open-Angle Glaucoma

Ocular Hypertension | Open-Angle Glaucoma

United States
Eximore Ltd.

Active, not recruiting

Safety, Tolerability, Plug Retention and Preliminary Efficacy of Tacrolimus-loaded Punctal Plug in Patients With Moderate to Severe Dry Eye Disease - Cohort B

Ocular Inflammation | Dry Eye | Keratoconjunctivitis Sicca

Mexico
Mati Therapeutics Inc.

Completed

Safety and Intraocular Lowering Effect of Delivery of Travoprost Evolute® in Subjects With Elevated Intraocular Pressure

Elevated Intraocular Pressure (IOP)

United States
Karolinska University Hospital

Completed

Percutaneous Plug-based Femoral Arteriotomy Closure Device Use in Surgery for Acute Type A Aortic Disection

Aortic Dissection

Sweden
Karolinska University Hospital

Completed

Percutaneous Plug-based Arteriotomy Closure Device Use in Minimally Invasive Mitral Valve Surgery

Mitral Valve Disease

Sweden
Acasti Pharma Inc.

Active, not recruiting

Comparative Bioavailability of Betamethasone Oral Solution Metered Spray (GTX-102) in Healthy Subjects

Ataxia Telangiectasia

Canada
Chinese PLA General Hospital

Recruiting

Decitabine and Anti-PD-1 in R/R DLBCL

Diffuse Large B Cell Lymphoma | Central Nervous System Lymphoma | Extranodal Extension | Relapse/Recurrence

China
Malaria Consortium

Recruiting

Innovative Intermittent Preventive Treatment Approaches to Reduce Malaria Burden in School-age Children in Burkina Faso (BF-IPTsc)

Malaria

Burkina Faso
Fondazione G.B. Bietti, IRCCS

Completed

Curcumin and Intravitreal Dexamethasone in Diabetic Macular Edema (DIABEC)

Diabetic Macular Edema

Italy
Eisai Inc.

Completed

A Phase II Study of the Safety and Efficacy of E7820 Plus Cetuximab in Colorectal Cancer, Preceded by a Run-in Study in Advanced Solid Tumors

Advanced Colorectal Cancer

United States, Canada
Cancer Institute and Hospital, Chinese Academy...

Recruiting

The Efficacy and Safety of Modified XELOX(mXELOX) Plus Cetuximab vs FOLFOX Plus Cetuximab in RAS and BRAF WT mCRC Pts

Colo-rectal Cancer

China
LEO Pharma

Completed

A Psoriasis Plaque Test With LEO 29102 Cream and Its Combination Products

Psoriasis Vulgaris

France
The Cleveland Clinic

Terminated

The Effect of Systemic or Perineural Dexamethasone on the Duration of Interscalene Nerve Blocks With Ropivacaine

Duration of Interscalene Block

United States
Second Affiliated Hospital, School of Medicine,...
The First Affiliated Hospital of Anhui Medical University; Huashan Hospital; China-Japan... and other collaborators

Not yet recruiting

Stereotactic Operation Integrating With Thrombolysis in Basal Ganglion Hemorrhage Evacuation II (SOITBE II)

Basal Ganglia Hemorrhage
LEO Pharma
Quintiles, Inc.

Completed

LEO 90105 Ointment in Japanese Subjects With Psoriasis

Psoriasis

Japan
LEO Pharma

Completed

Efficacy and Safety of Calcipotriol Plus Betamethasone Dipropionate Ointment in Patients With Psoriasis Vulgaris

Psoriasis Vulgaris

China
LEO Pharma

Completed

Efficacy and Safety of Calcipotriol Plus Betamethasone Gel in the Treatment of Scalp Psoriasis

Psoriasis of Scalp

Canada, Denmark, France, Norway, Portugal, Spain, Sweden, United Kingdom
LEO Pharma

Completed

Efficacy and Safety of Calcipotriol Plus Betamethasone Dipropionate Gel in Psoriasis Vulgaris

Psoriasis Vulgaris

Ireland, Germany, United Kingdom, Canada, Sweden
LEO Pharma

Completed

LEO 80185 in the Treatment of Psoriasis Vulgaris on the Non-scalp Regions of the Body (Trunk and/or Limbs)

Psoriasis Vulgaris

United States
LEO Pharma

Completed

Safety and Efficacy of TACLONEX Ointment in Adolescent Patients (Aged 12 to 17 Years) With Psoriasis Vulgaris

Psoriasis Vulgaris

United States
LEO Pharma

Completed

Efficacy and Safety of Calcipotriol Plus Betamethasone Dipropionate Gel in Scalp Psoriasis

Psoriasis of Scalp

Canada, Belgium, Finland, France, Germany, Netherlands, United Kingdom
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Low Dose Versus Standard Dose Dexamethasone for Reduction of Swelling in Patients With Primary or Metastatic Brain Tumors

Metastatic Malignant Neoplasm in the Brain | Malignant Brain Neoplasm | Recurrent Malignant Brain Neoplasm

United States
LEO Pharma

Completed

Efficacy and Safety of Calcipotriol Plus Betamethasone Dipropionate Gel for up to a Year in Scalp Psoriasis

Psoriasis of Scalp

Canada, Denmark, France, Germany, United Kingdom
Celgene

Completed

A Study of CC-5013 Plus Dexamethasone Versus Dexamethasone Alone in Previously Treated Subjects With Multiple Myeloma

Multiple Myeloma

Spain, United Kingdom, Switzerland, Australia, Israel, Italy, Poland, France, Belgium, Ireland, Austria, Germany, Ukraine, Greece, Sweden
LEO Pharma

Completed

Efficacy of Calcipotriol Plus Betamethasone Gel Versus Calcipotriol Scalp Solution in Scalp Psoriasis

Psoriasis of Scalp

France, Canada, Belgium, Denmark, Sweden
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Dexamethasone in Controlling Dyspnea in Patients With Cancer

Dyspnea | Malignant Neoplasm

United States
McMaster University
Icahn School of Medicine at Mount Sinai; Edward-Elmhurst Health System

Completed

Chalazion Conservative Treatment Trial

Chalazion Unspecified Eye, Unspecified Eyelid | Chalazion Left Eye, Unspecified Eyelid | Chalazion Right Eye, Unspecified Eyelid | Chalazion Both Eyes

United States, Canada
Sherif Mohamed Abd el moneim Soaida, MD

Completed

Dexamethasone & Bupivacaine vs Bupivacaine Alone in Combined Femoral and Sciatic Nerve Block for Perioperative Analgesia in Patients Undergoing Lower Limb Surgeries

Pain

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