Search clinical trials for: Oral immediate-released morphine

Total 510 results

Elcelyx Therapeutics, Inc.

Completed

Assessing the PK and Effect on Glucose and GI Hormone Concentrations of Metformin Delayed-Release in Subjects With T2DM

Type 2 Diabetes Mellitus

United States
Tulane University
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Building Engagement Using Financial Incentives Trial - Hypertension (BENEFIT-H)

Hypertension | Patient Engagement | Health Behavior | Adherence, Patient | Healthcare Patient Acceptance
ApoPharma

Completed

Pilot Study of the Pharmacokinetic Profile of Deferiprone Sustained-Release Formulation in Healthy Volunteers

Healthy

Canada
Velicept Therapeutics, Inc.

Completed

Evaluation of the Efficacy and Safety of Solabegron Tablets for Treatment of Overactive Bladder in Adult Women

Overactive Bladder

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A 5-treatment, Study in Healthy Volunteers to Assess The Safety, Tolerability, and Pharmacokinetics of Four Controlled Release (CR) Pregabalin Tablet Formulations and the Immediate Release (IR) Formulation Administered Fasted

Healthy

Belgium
University of Louisville
Bausch Health Americas, Inc.

Completed

Pharmacokinetics of Immediate-Release vs. Delayed-Release Omeprazole in Gastroparesis

Gastroesophageal Reflux Disease | Gastroparesis

United States
NYU Langone Health

Completed

A Within-Subject Cross-Over Comparison Between Immediate Release and Extended Release Adderall

Attention Deficit Hyperactivity Disorder

United States
Max Zeller Soehne AG

Completed

Pilot Pharmacokinetic Study of a Prolonged-release Formulation of St. John's Wort Extract Ze 117

Healthy

Germany
M. Eugenia Socias
Canadian Institutes of Health Research (CIHR); Mayne Pharma International Pty... and other collaborators

Terminated

Slow-Release Oral Morphine for the Treatment of Opioid Use Disorder (pRESTO)

Opioid-Related Disorders | Opiate Substitution Treatment | Morphine | Fentanyl | Methadone

Canada
Pouya Azar

Recruiting

Symptom-inhibited Fentanyl Induction (SIFI)

Opioid Use Disorder

Canada
Pfizer

Completed

Clinical Study to Evaluate Blood Concentrations of PF-06700841 After Oral Dose as Different Formulations

Healthy Participants

Belgium
Pfizer

Completed

Evaluation of Risk Minimization, Assessment and Outcomes in Patients With Chronic Pain Taking Avinza (ACCESS 2008)

Pain

United States, Puerto Rico
Thomas Jefferson University
National Institute on Drug Abuse (NIDA)

Completed

Buprenorphine for the Treatment of Neonatal Abstinence Syndrome

Neonatal Abstinence Syndrome

United States
Scilex Pharmaceuticals, Inc.

Completed

Study to Evaluate the Safety of SP-104

Healthy Volunteers

New Zealand
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

Study on the Safety and Effectiveness of Switching Between Two Forms of Tapentadol in Patients With Chronic Low Back Pain

Low Back Pain
Tris Pharma, Inc.

Terminated

CORAL - Cebranopadol Versus Morphine Prolonged-release in Patients With Chronic Moderate to Severe Pain Related to Cancer (CORAL)

Neoplasms | Pain | Chronic Pain

Croatia, Austria, Belgium, Bulgaria, Denmark, Germany, Hungary, Poland, Romania, Serbia, Slovakia, Chile, Spain, United Kingdom
Alcobra Ltd.

Completed

A 6 Week Study of MG01CI 1400 mg Compared With Placebo in Adults With ADHD ( Attention Deficit/Hyperactivity )

ADHD | Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type

United States, Israel
Pfizer

Completed

A Randomized, Open Label, Clinical Trial of the Pharmacokinetics of Azithromycin Following a Single Dose of Azithromycin Sustained Release (2 Gram) or Commercial Azithromycin Tablet (500 mg) to Cancer Patients That Require Lung Surgery

Pharmacokinetics

Italy
McGill University Health Centre/Research Institute...

Unknown

Efficacy and Safety of Ultra-low Dose Methadone as Adjuvant Analgesic in Cancer Patients With Pain (UDOME)

Pain, Intractable

Canada
Pfizer

Completed

A Study to Learn About the Study Medication, Zavegepant, in Healthy Volunteers

Biological Availability

United States
Universidade Federal de Alfenas
Fundação de Amparo à Pesquisa do estado de Minas Gerais

Recruiting

Epidural Association of Morphine and Ropivacaine for Cancer Pain Treatment

Quality of Life | Palliative Care | Opioid Use | Cancer Pain | Cost Analysis | Epidural Route | Morphine-ropivacaine Association | Rational Use of Medication

Brazil
Royal Brompton & Harefield NHS Foundation Trust

Completed

Morphine Sulfate/Placebo for the Treatment of PulmonAry Fibrosis Cough (PAciFy Cough)

Idiopathic Pulmonary Fibrosis

United Kingdom
Vanderbilt University Medical Center
National Institute on Drug Abuse (NIDA)

Recruiting

Low-dose Buccal Buprenorphine: Relative Abuse Potential and Analgesia

Pain | Analgesia | Abuse Opioids

United States
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Morphine for Treatment of Dyspnea in Patients With COPD (MORDYC)

Pulmonary Disease, Chronic Obstructive

Netherlands
GlaxoSmithKline

Terminated

Crossover Study to Evaluate the Comparative Bioavailability of Two Fixed Dose Combination Tablet Formulations of Extended Release Metformin and Extended Release Glimepiride in Health Volunteers

Diabetes Mellitus, Type 2

Australia
Mallinckrodt

Completed

Drug Interactions Between Morphine and Orally or IV Administered Acetaminophen

Pain

United States
Reckitt Benckiser Healthcare (UK) Limited
Premier Research Group plc

Completed

Efficacy of 300 mg Ibuprofen Prolonged-Release Tablets for the Treatment of Pain After Surgical Removal of Impacted Third Molars

Pain

United States
Heleen Grootjans
Chiesi Farmaceutici S.p.A.

Recruiting

Trial Comparing Immediate Versus Extended Release Tacrolimus; Reducing Calcineurin Inhibitor Related Toxicity in Lung Transplantation Patients (REVOLUTION)

Lung Transplant; Complications

Netherlands
Mayo Clinic

Terminated

Extended-Release Melatonin in Patients With Rapid Eye Movement Sleep Behavior Disorder

Parkinson Disease | Rapid Eye Movement Sleep Behavior Disorder

United States
University Hospital Schleswig-Holstein

Completed

Safety and Pharmacokinetics of Oral Controlled-ileocolonic-release Nicotinamide (CICR-NAM)

Safety Issues | Pharmacokinetic

Germany
Pfizer

Withdrawn

A Study to Evaluate the Safety and Efficacy of Three Doses of a Controlled Release Formulation of Varenicline for Smoking Cessation

Smoking Cessation
Pfizer

Completed

A Phase 1 Study To Evaluate The Pharmacokinetics And Safety Of Three Modified Release And One Immediate Release Formulations Of Tofacitinib (CP-690,550) In Healthy Volunteers

Healthy

Singapore
University of California, Los Angeles
Veloxis Pharmaceuticals

Active, not recruiting

Envarsus XR® in Adolescent Renal Transplant Recipients (EnvarsusXR)

Kidney Transplantation | Renal Transplantation | Grafting, Kidney

United States
Pharmavite LLC
KGK Science Inc.

Completed

A Study to Investigate the Pharmacokinetics of Prolonged-release Melatonin Compared to Standard, Immediate-release Melatonin in Healthy Adults

Healthy

Canada
AstraZeneca

Completed

SR-Registration Study 1, ROW: Efficacy and Safety of Seroquel® in the Treatment of Patients With Schizophrenia

Schizophrenic Disorder

Bulgaria, Russian Federation, Romania, South Africa, Greece, Philippines, India, Indonesia
Vastra Gotaland Region
Sahlgrenska University Hospital, Sweden; The Gothenburg Society of Medicine; Åke... and other collaborators

Not yet recruiting

Treatment Study in Patients Treated With Both Insulin & Hydrocortisone (INSCORT)

Diabetes Mellitus | Adrenal Insufficiency | Polyglandular Autoimmune Syndrome

Sweden
University of Rochester

Terminated

Open-Label Trial Comparing Oxycodone Medications (OUTCOMES)

Chronic Pain

United States
AstraZeneca

Completed

Study Comparing the Tolerability of Seroquel IR With Seroquel XR in Patients With Bipolar Depression

Bipolar Depression
University of Minnesota

Completed

Comparison of the Cognitive and Motor Effects of Treatment Between an Immediate- and Extended-release Tacrolimus (Envarsus® XR) Based Immunosuppression Regimen in Kidney Transplant Recipients

Kidney Transplant Failure and Rejection

United States
Antonios Likourezos

Withdrawn

A Study Comparing Recurrent Use of MSIR, Percocet, and Vicodin at Discharge From the ED

Pain

United States
Actelion

Completed

A Study of Selexipag in Healthy Male Participant

Healthy

Belgium
Allina Health System

Completed

Perioperative Pain Management In Spine Surgery Patients: Part I

Pain

United States
Institut Bergonié

Completed

Morphine After Radiofrequency Ablation of Painful Bone Metastases in Patients With Cancer (MEDOR)

Pain | Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer

France
Pfizer

Completed

Abuse Potential of Orally Administered Crushed Embeda Compared to Crushed Controlled-Release Morphine and Placebo in Non-Dependent Recreational Opioid Users

Nondependent Opioid Abuse, Episodic

United States
NYU Langone Health

Completed

Envarsus XR in Lung Transplant

Lung Transplant

United States
GlaxoSmithKline

Completed

A Comparison of Ropinirole Immediate Release With Ropinirole Prolonged Release in Patients With Advanced Parkinson's

Parkinson Disease

Spain, France, Bulgaria, United Kingdom, Germany, Hungary, Russian Federation, South Africa, Italy, Canada, Czechia, Poland, Romania, Ukraine
Azurity Pharmaceuticals

Completed

An Abuse Potential Study of Orally Administered HORIZANT in Healthy, Non-dependent, Recreational Drug Users

Abuse Potential

United States
Johnson & Johnson Taiwan Ltd

Terminated

A Study to Compare Safety and Efficacy of Osmotic Release Oral Syytem (OROS) Hydromorphone Hydrochloride (HCl) With Morphine Sustain Release (SR) in Participants With Cancer Pain

Cancer Pain
Diurnal Limited

Completed

Comparison of Chronocort Versus Standard Hydrocortisone Replacement Therapy in Participants Aged 16 Years and Over With Congenital Adrenal Hyperplasia (CONnECT)

Congenital Adrenal Hyperplasia

France, United States, Japan
Galderma R&D

Completed

Patient Centered Outcomes in Rosacea: An Exploratory Multi-media Analysis of the Patient Experience on Oracea

Papulopustular Rosacea

United States

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