Search clinical trials for: PBI-4547

Total 2433 results

National Cancer Institute (NCI)

Recruiting

Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer

Breast Cancer | Multiple Myeloma | Ovarian Cancer | Non-Small Cell Lung Cancer | Neuroendocrine Tumors | Gastrointestinal/Genitourinary Cancers | Endocrine Tumors

United States
National Cancer Institute (NCI)

Completed

T Cell Receptor Immunotherapy Targeting MAGE-A3 for Patients With Metastatic Cancer Who Are HLA-DP0401 Positive

Melanoma | Cervical Cancer | Breast Cancer | Renal Cancer | Urothelial Cancer

United States
AbbVie

Completed

Elagolix Versus Subcutaneous Depot Medroxyprogesterone Acetate for the Treatment of Endometriosis (PETAL)

Endometriosis
Neurocrine Biosciences

Completed

Study to Assess the Effect of Ketoconazole on the Pharmacokinetics of NBI-98854 in Healthy Subjects

Effect of Ketoconazole on the PK of NBI-98854 in Healthy Subjects

United States
Bristol-Myers Squibb

Terminated

Belatacept in Liver Transplant Recipients

Immunosuppression in Solid Organ Transplant

France, Germany, Italy, United States, Austria, Canada, Spain, Argentina, Brazil
B.P. Koirala Institute of Health Sciences

Unknown

Effect of Intraperitoneal Nebulisation of Magnesium Sulphate for Analgesia Following Laparoscopic Cholecystectomy

Postoperative Pain

Nepal
University Hospital of Split
Dr Ivancica Pavlicevic Family Practice Office

Completed

Interaction Between Antihypertensives and Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

Hypertension

Croatia
Celcuity, Inc.

Recruiting

Gedatolisib Plus Fulvestrant With or Without Palbociclib vs Standard-of-Care for the Treatment of Patients With Advanced or Metastatic HR+/HER2- Breast Cancer (VIKTORIA-1) (VIKTORIA-1)

Breast Cancer

Korea, Republic of, United States, Belgium, United Kingdom, Taiwan, France, Italy, Australia, Singapore, Argentina, Canada, India, Mexico, Czechia, Spain, Austria, Bulgaria, Germany, Hungary, Poland, Brazil, Greece, Romania
NYU Langone Health
National Institute on Aging (NIA)

Recruiting

Aβ Dynamics in LLMD

Alzheimer Disease | Major Depressive Disorder

United States
University of Washington
Aadi Bioscience, Inc.

Active, not recruiting

Nab-Sirolimus and Pazopanib Hydrochloride in Treating Patients With Advanced Nonadipocytic Soft Tissue Sarcomas

Advanced Soft Tissue Sarcoma | Metastatic Soft Tissue Sarcoma | Locally Advanced Soft Tissue Sarcoma

United States
LMU Klinikum

Completed

Musculoskeletal Nociceptive Pain in Participants With Neuromuscular Disorders

Healthy | Myotonic Dystrophy Type 2 | Pompe Disease (Late-onset) | Spinal Muscular Atrophy Type 3 | Myotonic Dystrophy Type 1 (DM1) | Facioscapulohumeral Muscular Dystrophy 1 | Inclusion Body Myositis, Sporadic

Germany
Chinese PLA General Hospital

Completed

Phase 2 Trial of Nab-paclitaxel Plus S-1 vs Gemcitabine Plus Cisplatin as 1-line Chemotherapy of Patients With Local Advanced and/or Metastatic Transitional Cell Carcinoma of Urothelial Tract

Carcinoma, Transitional Cell

China
Georgetown University
National Cancer Institute (NCI)

Terminated

Phase I Study of Lenalidomide, Rituximab and Ibrutinib in Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL)

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
Chinese PLA General Hospital

Unknown

Phase 2 Trial of Gemcitabine vs S-1 vs Gemcitabine Plus Nab-paclitaxel as Adjuvant Chemotherapy of Post-operative Pancreatic Cancer Patients

Cancer of Pancreas

China
Medicines for Malaria Venture
Syneos Health; Nucleus Network Ltd

Completed

Study To Investigate The Relative Bioavailability of OZ439 Formulations In Healthy Volunteers

Healthy Volunteers

Australia
Tibotec BVBA

Completed

An Open-Label Study of Telaprevir Administered Every 12 or 8 Hours in Combination With One of Two Pegylated Interferons and Ribavirin in Treatment-Naive Genotype 1 Chronic Hepatitis C Participants

Chronic Hepatitis C

France, Spain, Belgium, Germany, Austria, Netherlands
ASST Fatebenefratelli Sacco

Completed

Sodium Picosulphate/Magnesium Citrate and Low-volume PEG -Ascorbic Acid as Preparation for Colonoscopy

Colon Cleansing for Colonoscopy

Italy
Glaxo Wellcome

Completed

A Phase I Trial to Evaluate the Safety, Pharmacokinetics and Antiviral Activity of 141W94 After Multiple Dosing in Patients With HIV Infection

HIV Infections

United States
National Cancer Institute (NCI)

Recruiting

Pomalidomide Treatment in Patients With Kaposi Sarcoma

Skin Kaposi Sarcoma

United States
OHSU Knight Cancer Institute
Oregon Health and Science University; Celgene Corporation

Completed

Nab-paclitaxel and Gemcitabine Hydrochloride Followed by Radiation Therapy Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery

Pancreatic Adenocarcinoma | Resectable Pancreatic Carcinoma

United States
Refnot-Pharm Ltd

Completed

Effect of Refnot on Immunity in Cancer Patients (R-2)

Solid Tumor
National Cancer Institute (NCI)

Completed

CAR T Cell Receptor Immunotherapy Targeting EGFRvIII for Patients With Malignant Gliomas Expressing EGFRvIII

Glioblastoma | Brain Cancer | Malignant Glioma | Gliosarcoma

United States
Memorial Sloan Kettering Cancer Center

Terminated

Biparental HLA Haplotype Disparate T-cell Depleted Transplants for Patients Lacking an HLACompatible Donor

Acute Leukemia | Myelodysplastic Syndrome | Non-Hodgkins Lymphoma | Chronic Leukemia

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0410 Tandem Stem Cell Transplantation in Treating Patients With Progressive or Recurrent Hodgkin's Lymphoma

Lymphoma

United States
National Cancer Institute (NCI)

Completed

Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Stage IIIA Non-small Cell Lung Cancer

Stage IIIA Non-small Cell Lung Cancer

United States
Children's Hospital of Philadelphia
Cystic Fibrosis Foundation

Terminated

Phenylbutyrate/Genistein Duotherapy in Delta F508-Heterozygotes (for Cystic Fibrosis)

Cystic Fibrosis

United States
Hannover Medical School

Unknown

Studying the Effect of Changing Immunosuppression in Case of Polyoma BK Virus Infection of the Renal Transplant (BKVIRUS)

Virus Diseases | Disorder Related to Renal Transplantation | Immunosuppression Related Infectious Disease

Germany
Children's Hospital of Philadelphia
National Center for Research Resources (NCRR); Cystic Fibrosis Foundation

Completed

Phenylbutyrate/Genistein Duotherapy in Delta F508-Homozygous(for Cystic Fibrosis)

Cystic Fibrosis
Radboud University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

The Potential Role for Adenosine in the Haemodynamic Effects of Free Fatty Acids

Obesity | Metabolic Syndrome X

Netherlands
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Not yet recruiting

A Study of Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection in Chinese Participants With Acute Gout

Acute Gout
Hadassah Medical Organization

Recruiting

Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers

Non Small Cell Lung Cancer | Metastatic Cancer | Triple Negative Breast Cancer | Sarcoma, Synovial | Ovary Cancer | Sarcoma,Soft Tissue | Melanoma Stage IV | Bladder Urothelial Carcinoma | Neuroblastoma, Metastatic

Israel
Hacettepe University
Ankara City Hospital Bilkent

Completed

Preoperative Nutritional Status and Postoperative Outcomes in Colorectal Cancer

Colorectal Cancer

Turkey
SCRI Development Innovations, LLC
Eli Lilly and Company; Celgene Corporation

Completed

Neo-adjuvant Gemcitabine, Epirubicin, ABI-007 (GEA) in Locally Advanced or Inflammatory Breast Cancer

Breast Cancer

United States
Zimmer Biomet

Terminated

A Clinical Registry to Collect Patient Outcome Date for the BIOMET® Stimulator Systems

Fractures, Ununited | Fusion of Spine (Disease)

United States
Nantes University Hospital

Completed

A Study of Mycophenolate Mofetil and Cyclosporin, Without Concomitant Corticosteroids, After a First Renal Transplant

Renal Transplantation

France
Taipei Veterans General Hospital, Taiwan

Not yet recruiting

The Application and Validation of Triple Drug Response Surface Models on Density Spectral Array in Clinical Anesthesia

Anesthesia | Drug Interaction | Anesthesia; Functional

Taiwan
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Ipilimumab, Nivolumab, and Radiation Therapy in Treating Patients With HPV Positive Advanced Oropharyngeal Squamous Cell Carcinoma

Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7 | Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma... and other conditions

United States
Hospices Civils de Lyon

Completed

Staphylococcal Acute Post-Operative PJI Treated With 'DAIR' And Impact Of Rifampin (IPASTAPH)

Bone and Joint Infection | Antibiotic Resistant Staphylococcus Aureus Infection

France
University of Washington
National Cancer Institute (NCI)

Completed

Sargramostim and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer That Did Not Respond to Previous Chemotherapy

Fallopian Tube Cancer | Peritoneal Cavity Cancer | Ovarian Clear Cell Cystadenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Ovarian Serous Cystadenocarcinoma | Stage IV Ovarian Epithelial Cancer | Brenner Tumor | Recurrent Ovarian Epithelial Cancer | Stage III Ovarian Epithelial Cancer | Ovarian Mucinous... and other conditions

United States
Tel-Aviv Sourasky Medical Center
Tel Aviv Medical Center

Completed

Platelet Inhibitory Effect of Clopidogrel in Patients Treated With Omeprazole, Pantoprazole, or Famotidine

Coronary Heart Disease | GI Bleeding

Israel
The 108 Military Central Hospital
Charles Drew University of Medicine and Science

Completed

Arabinoxylan Rice Bran (MGN-3/Biobran) for the Treatment of Hepatocellular Carcinoma and Hepatitis B and C Infection

Hepatitis B | Hepatocellular Carcinoma

Vietnam
National Cancer Institute (NCI)

Recruiting

Comparing the Addition of an Anti-Cancer Drug, Pomalidomide, to the Usual Chemotherapy Treatment (Daunorubicin and Cytarabine Liposome) in Newly Diagnosed Acute Myeloid Leukemia With Myelodysplastic Syndrome-Related Changes

Acute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Acute Myeloid Leukemia With Multilineage Dysplasia | Acute Myeloid Leukemia Post Cytotoxic Therapy

United States
Manuel Coelho da Rocha

Not yet recruiting

Tailored vs. Empirical Helicobacter Pylori Infection Treatment

Helicobacter Pylori Infection

Portugal
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

Gemcitabine Hydrochloride and Cisplatin With or Without Nab-Paclitaxel in Treating Patients With Newly Diagnosed Advanced Biliary Tract Cancers

Stage III Intrahepatic Cholangiocarcinoma AJCC v8 | Stage IIIA Intrahepatic Cholangiocarcinoma AJCC v8 | Stage IIIB Intrahepatic Cholangiocarcinoma AJCC v8 | Stage III Gallbladder Cancer AJCC v8 | Stage IIIA Gallbladder Cancer AJCC v8 | Stage IIIB Gallbladder Cancer AJCC v8 | Unresectable Extrahepatic... and other conditions

United States
Oncotherapeutics
Celgene Corporation

Terminated

Pomalidomide for Lenalidomide for Relapsed or Refractory Multiple Myeloma Patients

Multiple Myeloma

United States
Mayo Clinic

Recruiting

Molecular Breast Imaging Guidance for Breast Biopsy for Patients With Breast Abnormalities

Breast Neoplasm

United States
Alice Bertaina
California Institute for Regenerative Medicine (CIRM)

Recruiting

Early Trial of Allogeneic Hematopoietic Stem Cell Transplantation for Patients Who Will Receive a Kidney Transplant From the Same Donor

CKD Stage 4 | Cystinosis | FSGS | SLE Nephritis | SIOD

United States
Therapeutic Advances in Childhood Leukemia Consortium
Genzyme, a Sanofi Company

Completed

Clofarabine and Low Dose Total Body Irradiation as a Preparative Regimen for Stem Cell Transplant in Leukemia.

Acute Myeloid Leukemia | Leukemia Lymphoblastic, Acute | Neoplasm Recurrent

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Active, not recruiting

Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMTCTN1507)

Sickle Cell Disease

United States
University of Guadalajara
Hospital Civil de Guadalajara; Cell Pharma

Completed

Pirfenidone Plus M-DDO Gel in Moderate and Severe Acne

Acne Vulgaris Superficial Mixed Comedonal and Inflammatory

Mexico

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